EC: 2.6.1.1

aspartate transaminase (L-aspartate:2-oxoglutarate aminotransferase)

enzyme lambda metabolic reaction experiment
uniprot:E9L7A5 [aspartate transaminase(Enzyme)]

Oxaloacetate + L_Glutamate -> 2_Oxoglutarate + L_Aspartate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM sodium phosphate
PH: 8
Temperature: 37
uniprot:Q9SIE1 [aspartate transaminase(Enzyme)]

Oxaloacetate + L_Glutamate -> L_Aspartate + 2_Oxoglutarate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM sodium phosphate
PH: 8
Temperature: 37
uniprot:Q9SIE1 [aspartate transaminase(Enzyme)]

Prephenate + L_Aspartate -> Oxaloacetate + L_Arogenate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM sodium phosphate
PH: 8
Temperature: 37
uniprot:E9L7A5 [aspartate transaminase(Enzyme)]

2_Oxoglutarate + L_Arogenate -> Prephenate + L_Glutamate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM sodium phosphate
PH: 8
Temperature: 37
uniprot:Q9SIE1 [aspartate transaminase(Enzyme)]

L_Glutamate + Prephenate -> 2_Oxoglutarate + L_Arogenate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM sodium phosphate
PH: 8
Temperature: 37
uniprot:Q9SIE1 [aspartate transaminase(Enzyme)]

L_Glutamate + Oxaloacetate -> L_Aspartate + 2_Oxoglutarate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM sodium phosphate
PH: 8
Temperature: 37
uniprot:E9L7A5 [aspartate transaminase(Enzyme)]

Oxaloacetate + L_Glutamate -> 2_Oxoglutarate + L_Aspartate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM sodium phosphate
PH: 8
Temperature: 37
uniprot:E9L7A5 [aspartate transaminase(Enzyme)]

L_Aspartate + Prephenate -> Oxaloacetate + L_Arogenate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM sodium phosphate
PH: 8
Temperature: 37
uniprot:E9L7A5 [aspartate transaminase(Enzyme)]

L_Glutamate + Prephenate -> 2_Oxoglutarate + L_Arogenate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM sodium phosphate
PH: 8
Temperature: 37
- [aspartate transaminase(Enzyme) wildtype isoform I]

L_Aspartate + 2_Oxoglutarate -> L_Glutamate + Oxaloacetate		 (( (( (Vmax * A) ) * B) ) / (( (( (Km_A * B) ) + (Km_B * A)) ) + (A * B))) buffer: 0.1 M Tris-Cl, 6.5 U/ml pig heart malate dehydrogenase, 0.13 mM NADH
PH: 7.5
Temperature: 30
- [aspartate transaminase(Enzyme) wildtype isoform II]

2_Oxoglutarate + L_Aspartate -> Oxaloacetate + L_Glutamate		 (( (( (Vmax * A) ) * B) ) / (( (( (Km_A * B) ) + (Km_B * A)) ) + (A * B))) buffer: 0.1 M Tris-Cl, 6.5 U/ml pig heart malate dehydrogenase, 0.13 mM NADH
PH: 7.5
Temperature: 30
- [aspartate transaminase(Enzyme) wildtype isoform I]

Oxaloacetate + L_Glutamate -> L_Aspartate + 2_Oxoglutarate		 (( (( (Vmax * A) ) * B) ) / (( (( (Km_A * B) ) + (Km_B * A)) ) + (A * B))) buffer: 0.1 M Tris-Cl, 6.5 U/ml pig heart malate dehydrogenase, 0.13 mM NADH
PH: 7.5
Temperature: 32
- [aspartate transaminase(Enzyme) wildtype isoform II]

L_Glutamate + Oxaloacetate -> L_Aspartate + 2_Oxoglutarate		 (( (( (Vmax * A) ) * B) ) / (( (( (Km_A * B) ) + (Km_B * A)) ) + (A * B))) buffer: 0.1 M Tris-Cl, 6.5 U/ml pig heart malate dehydrogenase, 0.13 mM NADH
PH: 7.5
Temperature: 32
uniprot:P00503 [aspartate transaminase(Enzyme) wildtype anionic isozyme]

2_Oxoglutarate + L_Aspartate -> Oxaloacetate + L_Glutamate		 (( (V_1 * (( (A * B) ) - (( (P * Q) ) / Keq))) ) / (( (( (( (( (( (( (( (Kb * A) ) + (Ka * B)) ) + (A * B)) ) + (( (( (Kia * Kb) ) * P) ) / Kip)) ) + (( (( (Ka * Kib) ) * Q) ) / Kiq)) ) + (( (( (( (Ka * Kib) ) * P) ) * Q) ) / (Kp * Kiq))) ) + (( (( (Kb * A) ) * P) ) / Kip)) ) + (( (( (Ka * B) ) * Q) ) / Kiq))) buffer: 0.1 M arsenate
PH: 7.4
Temperature: 37
uniprot:P00506 [aspartate transaminase(Enzyme) wildtype cationic isozyme]

2_Oxoglutarate + L_Aspartate -> L_Glutamate + Oxaloacetate		 (( (V_1 * (( (A * B) ) - (( (P * Q) ) / Keq))) ) / (( (( (( (( (( (( (( (Kb * A) ) + (Ka * B)) ) + (A * B)) ) + (( (( (Kia * Kb) ) * P) ) / Kip)) ) + (( (( (Ka * Kib) ) * Q) ) / Kiq)) ) + (( (( (( (Ka * Kib) ) * P) ) * Q) ) / (Kp * Kiq))) ) + (( (( (Kb * A) ) * P) ) / Kip)) ) + (( (( (Ka * B) ) * Q) ) / Kiq))) buffer: 0.1 M arsenate
PH: 7.4
Temperature: 37
uniprot:P46644 [aspartate transaminase(Enzyme)]

2_Oxoglutarate + L_Aspartate -> Oxaloacetate + L_Glutamate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate
PH: 8
Temperature: 37
uniprot:P46248 [aspartate transaminase(Enzyme)]

2_Oxoglutarate + L_Aspartate -> Oxaloacetate + L_Glutamate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate
PH: 8
Temperature: 37
uniprot:P46643 [aspartate transaminase(Enzyme)]

2_Oxoglutarate + L_Aspartate -> Oxaloacetate + L_Glutamate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate
PH: 8
Temperature: 37
- [aspartate transaminase(Enzyme) wildtype]

L_Aspartate + 2_Oxoglutarate -> Oxaloacetate + L_Glutamate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Glycylglycine, 0.15 mM NADH, 0.6 IU malate dehydrogenase
PH: 9
Temperature: 37
- [aspartate transaminase(Enzyme) wildtype]

2_Oxoglutarate + L_Aspartate -> L_Glutamate + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Glycylglycine, 0.15 mM NADH, 0.6 IU malate dehydrogenase
PH: 9
Temperature: 37
uniprot:P13221 [Pyridoxal phosphate]

2_Oxoglutarate + L_Aspartate -> L_Glutamate + Oxaloacetate		 (( (( (Vmax * A) ) * B) ) / (( (( (KmB * A) ) + (KmA * B)) ) + (A * B))) buffer: 33 mM phosphate, 66.7 µg/ml NADH, 1.67 µg/ml malic dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P13221 [Pyridoxal phosphate]

2_Oxoglutarate + L_Aspartate -> Oxaloacetate + L_Glutamate		 (( (( (Vmax * A) ) * B) ) / (( (( (KmB * A) ) + (KmA * B)) ) + (A * B))) buffer: 33 mM phosphate, 66.7 µg/ml NADH, 1.67 µg/ml malic dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P13221 [Pyridoxal phosphate]

L_Glutamate + Oxaloacetate -> L_Aspartate + 2_Oxoglutarate		 (( (( (Vmax * A) ) * B) ) / (( (( (KmB * A) ) + (KmA * B)) ) + (A * B))) buffer: 0.09 M sodium pyrophosphate
PH: 8
Temperature: 37
uniprot:P13221 [Pyridoxal phosphate]

L_Glutamate + Oxaloacetate -> 2_Oxoglutarate + L_Aspartate		 (( (( (Vmax * A) ) * B) ) / (( (( (KmB * A) ) + (KmA * B)) ) + (A * B))) buffer: 0.09 M sodium pyrophosphate
PH: 8
Temperature: 37
uniprot:P00507 [Pyridoxal phosphate]

2_Oxoglutarate + L_Aspartate -> Oxaloacetate + L_Glutamate		 (( (( (Vmax * A) ) * B) ) / (( (( (KmB * A) ) + (KmA * B)) ) + (A * B))) buffer: 33 mM phosphate, 66.7 µg/ml NADH, 1.67 µg/ml malic dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P00507 [Pyridoxal phosphate]

2_Oxoglutarate + L_Aspartate -> Oxaloacetate + L_Glutamate		 (( (( (Vmax * A) ) * B) ) / (( (( (KmB * A) ) + (KmA * B)) ) + (A * B))) buffer: 33 mM phosphate, 66.7 µg/ml NADH, 1.67 µg/ml malic dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P00507 [Pyridoxal phosphate]

L_Aspartate + 2_Oxoglutarate -> Oxaloacetate + L_Glutamate		 (( (( (Vmax * A) ) * B) ) / (( (( (KmB * A) ) + (KmA * B)) ) + (A * B))) buffer: 33 mM phosphate, 66.7 µg/ml NADH, 1.67 µg/ml malic dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P00507 [Pyridoxal phosphate]

L_Glutamate + Oxaloacetate -> L_Aspartate + 2_Oxoglutarate		 (( (( (Vmax * A) ) * B) ) / (( (( (KmB * A) ) + (KmA * B)) ) + (A * B))) buffer: 0.09 M sodium pyrophosphate
PH: 8
Temperature: 37
uniprot:P00507 [Pyridoxal phosphate]

Oxaloacetate + L_Glutamate -> L_Aspartate + 2_Oxoglutarate		 (( (( (Vmax * A) ) * B) ) / (( (( (KmB * A) ) + (KmA * B)) ) + (A * B))) buffer: 0.09 M sodium pyrophosphate
PH: 8
Temperature: 37
uniprot:P00507 [Pyridoxal phosphate]

Oxaloacetate + L_Glutamate -> L_Aspartate + 2_Oxoglutarate		 (( (( (Vmax * A) ) * B) ) / (( (( (KmB * A) ) + (KmA * B)) ) + (A * B))) buffer: 0.09 M sodium pyrophosphate
PH: 8
Temperature: 37
uniprot:P13221 [aspartate transaminase(Enzyme) wildtype]

2_Oxoglutarate + L_Aspartate -> L_Glutamate + Oxaloacetate		 (Vmax / (( (( (( (KmB / B) ) * (1 + (A / KiA))) ) + (( (KmA / A) ) * (1 + (B / KiB)))) ) + 1)) buffer: 75 mM Tris-HCl, 0.1 % bovine serum albumin, 20 µM pyridoxal phosphate
PH: 8.6
Temperature: 36
uniprot:P00507 [aspartate transaminase(Enzyme) wildtype]

2_Oxoglutarate + L_Aspartate -> L_Glutamate + Oxaloacetate		 (Vmax / (( (( (( (KmB / B) ) * (1 + (A / KiA))) ) + (( (KmA / A) ) * (1 + (B / KiB)))) ) + 1)) buffer: 75 mM Tris-HCl, 0.1 % bovine serum albumin, 20 µM pyridoxal phosphate
PH: 8.6
Temperature: 36
uniprot:P00507 [aspartate transaminase(Enzyme) wildtype]

3_Sulfino_L_alanine + 2_Oxoglutarate -> 3_Sulfinylpyruvate + Glutamate		 (Vmax / (( (( (( (KmB / B) ) * (1 + (A / KiA))) ) + (( (KmA / A) ) * (1 + (B / KiB)))) ) + 1)) buffer: 75 mM Tris-HCl, 0.1 % bovine serum albumin, 20 µM pyridoxal phosphate
PH: 8.6
Temperature: 36
uniprot:P13221 [aspartate transaminase(Enzyme) wildtype]

2_Oxoglutarate + 3_Sulfino_L_alanine -> Glutamate + 3_Sulfinylpyruvate		 (Vmax / (( (( (( (KmB / B) ) * (1 + (A / KiA))) ) + (( (KmA / A) ) * (1 + (B / KiB)))) ) + 1)) buffer: 75 mM Tris-HCl, 0.1 % bovine serum albumin, 20 µM pyridoxal phosphate
PH: 8.6
Temperature: 36
uniprot:P17174 [Maleate]

L_Aspartate + 2_Oxoglutarate -> Oxaloacetate + L_Glutamate		 (( (Vmax * S2) ) / (( (Km * (1 + (I / Ki))) ) + S2)) buffer: 16.7 mM Potassium phosphate
PH: 6.8
Temperature: 37
uniprot:P17174 [aspartate transaminase(Enzyme) wildtype]

L_Aspartate + 2_Oxoglutarate -> L_Glutamate + Oxaloacetate		 (( (Vmax * S2) ) / (Km + S2)) buffer: 16.7 mM Potassium phosphate
PH: 6.8
Temperature: 37
uniprot:P17174 [aspartate transaminase(Enzyme) wildtype]

2_Oxoglutarate + L_Aspartate -> Oxaloacetate + L_Glutamate		 (( (Vmax * S1) ) / (Km + S1)) buffer: 16.7 mM Potassium phosphate
PH: 6.8
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_MALATE-ASPARTATE-SHUTTLE-PWY malate-aspartate shuttle
BioCyc:HUMAN_ASPARAGINE-DEG1-PWY-1 asparagine degradation
BioCyc:HUMAN_PWY-5328 superpathway of methionine degradation
BioCyc:META_PWY-6628 superpathway of L-phenylalanine biosynthesis
BioCyc:META_PHESYN L-phenylalanine biosynthesis I
BioCyc:META_ASPARAGINE-DEG1-PWY-1 L-asparagine degradation III (mammalian)
BioCyc:META_ASPARTATE-DEG1-PWY L-aspartate degradation I
BioCyc:META_PWY-5345 superpathway of L-methionine biosynthesis (by sulfhydrylation)
BioCyc:META_CYSTEINE-DEG-PWY L-cysteine degradation I
BioCyc:META_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:META_PWY0-781 aspartate superpathway
BioCyc:META_HYDROXYPRODEG-PWY trans-4-hydroxy-L-proline degradation I
BioCyc:META_PWY-5328 superpathway of L-methionine salvage and degradation
BioCyc:ECO_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:ECO_GLUTDEG-PWY L-glutamate degradation II
BioCyc:YEAST_ASPBIO-PWY aspartate biosynthesis
BioCyc:ARA_PWY-3481 superpathway of L-phenylalanine and L-tyrosine biosynthesis
BioCyc:ARA_THRESYN-PWY superpathway of L-threonine biosynthesis
BioCyc:MOUSE_HYDROXYPRODEG-PWY 4-hydroxyproline degradation I
BioCyc:MOUSE_CYSTEINE-DEG-PWY L-cysteine degradation I
BioCyc:BSUB_ASPARTATE-DEG1-PWY L-aspartate degradation I
BioCyc:BSUB_PHESYN L-phenylalanine biosynthesis I
BioCyc:ECOL316407_GLUTDEG-PWY glutamate degradation II
BioCyc:ECOL316407_P4-PWY superpathway of lysine, threonine and methionine biosynthesis I
BioCyc:ECOL316407_ASPASN-PWY superpathway of aspartate and asparagine biosynthesis; interconversion of aspartate and asparagine
BioCyc:ECOL316407_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:ECOL316407_PWY0-781 aspartate superpathway
BioCyc:CORYNE_PWY0-781 aspartate superpathway
BioCyc:CORYNE_ASPARTATESYN-PWY L-aspartate biosynthesis
BioCyc:META_ASPASN-PWY superpathway of L-aspartate and L-asparagine biosynthesis
BioCyc:META_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:ECO_P4-PWY superpathway of L-lysine, L-threonine and L-methionine biosynthesis I
BioCyc:ECO_PWY0-1534 hydrogen sulfide biosynthesis I
BioCyc:ECO_ASPASN-PWY superpathway of L-aspartate and L-asparagine biosynthesis
BioCyc:MOUSE_PWY-5328 superpathway of methionine degradation
BioCyc:MOUSE_GLUTFUMARATE-PWY glutamine degradation II
BioCyc:MOUSE_GLUTOXA-PWY glutamate degradation VII
BioCyc:ECOL316407_ASPARTATESYN-PWY aspartate biosynthesis
BioCyc:ECOL316407_COMPLETE-ARO-PWY superpathway of phenylalanine, tyrosine, and tryptophan biosynthesis
BioCyc:CORYNE_PWY-5345 superpathway of L-methionine biosynthesis (by sulfhydrylation)
BioCyc:CORYNE_THRESYN-PWY superpathway of L-threonine biosynthesis
BioCyc:CORYNE_ASPARTATE-DEG1-PWY L-aspartate degradation I
BioCyc:HUMAN_PWY-6309 L-kynurenine degradation
BioCyc:HUMAN_HYDROXYPRODEG-PWY 4-hydroxyproline degradation
BioCyc:HUMAN_PWY-5329 L-cysteine degradation II
BioCyc:META_TYRSYN L-tyrosine biosynthesis I
BioCyc:META_ASPARTATESYN-PWY L-aspartate biosynthesis
BioCyc:META_GLUTDEG-PWY L-glutamate degradation II
BioCyc:META_MALATE-ASPARTATE-SHUTTLE-PWY L-aspartate degradation II
BioCyc:META_PWY-5347 superpathway of L-methionine biosynthesis (transsulfuration)
BioCyc:META_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:META_PWY-5329 L-cysteine degradation III
BioCyc:ECO_THRESYN-PWY superpathway of L-threonine biosynthesis
BioCyc:ECO_ASPARTATESYN-PWY L-aspartate biosynthesis
BioCyc:YEAST_MALATE-ASPARTATE-SHUTTLE-PWY aspartate degradation II
BioCyc:ARA_ASPARTATE-DEG1-PWY L-aspartate degradation I
BioCyc:ARA_PWY-3461 L-tyrosine biosynthesis II
BioCyc:MOUSE_MALATE-ASPARTATE-SHUTTLE-PWY aspartate degradation II
BioCyc:MOUSE_ASPBIO-PWY aspartate biosynthesis
BioCyc:BSUB_CYSTEINE-DEG-PWY L-cysteine degradation I
BioCyc:ECOL316407_PWY0-1534 hydrogen sulfide biosynthesis I
BioCyc:ECOL316407_THRESYN-PWY threonine biosynthesis
BioCyc:CORYNE_PWY-5347 superpathway of L-methionine biosynthesis (transsulfuration)
BioCyc:HUMAN_ASPARTATESYN-PWY aspartate biosynthesis
BioCyc:HUMAN_CYSTEINE-DEG-PWY L-cysteine degradation I
BioCyc:META_PWY-6318 L-phenylalanine degradation IV (mammalian, via side chain)
BioCyc:META_P4-PWY superpathway of L-lysine, L-threonine and L-methionine biosynthesis I
BioCyc:META_THRESYN-PWY superpathway of L-threonine biosynthesis
BioCyc:META_PWY-6309 L-tryptophan degradation XI (mammalian, via kynurenine)
BioCyc:META_PWY0-1534 hydrogen sulfide biosynthesis I
BioCyc:META_PWY-3001 superpathway of L-isoleucine biosynthesis I
BioCyc:ECO_TYRSYN L-tyrosine biosynthesis I
BioCyc:ECO_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:ECO_PWY0-781 aspartate superpathway
BioCyc:ECO_PHESYN L-phenylalanine biosynthesis I
BioCyc:ARA_ASPASN-ARA-PWY superpathway of aspartate and asparagine biosynthesis
BioCyc:ARA_PWY-3001 superpathway of L-isoleucine biosynthesis I
BioCyc:ARA_COMPLETE-ARO-ARA-PWY superpathway of phenylalanine, tyrosine and tryptophan biosynthesis
BioCyc:ARA_ASPARTATESYN-PWY L-aspartate biosynthesis
BioCyc:ARA_MALATE-ASPARTATE-SHUTTLE-PWY L-aspartate degradation II
BioCyc:ARA_PWY-3462 L-phenylalanine biosynthesis II
BioCyc:BSUB_GLUTDEG-PWY L-glutamate degradation II
BioCyc:ECOL316407_TYRSYN tyrosine biosynthesis I
BioCyc:ECOL316407_PHESYN phenylalanine biosynthesis I
BioCyc:CORYNE_PWY-3001 superpathway of L-isoleucine biosynthesis I
BioCyc:CORYNE_P4-PWY superpathway of L-lysine, L-threonine and L-methionine biosynthesis I
BioCyc:CORYNE_ASPASN-PWY superpathway of L-aspartate and L-asparagine biosynthesis
BioCyc:CORYNE_GLUTDEG-PWY L-glutamate degradation II
PathBank:SMP0000809 Aspartate Metabolism
PathBank:SMP0000811 L-Glutamate Metabolism
PathBank:SMP0000827 Phenylalanine Biosynthesis
PathBank:SMP0000833 Asparagine Biosynthesis
PathBank:SMP0000837 Threonine Biosynthesis
PathBank:SMP0000938 Phenylalanine Metabolism
PathBank:SMP0002078 Hydrogen Sulfide Biosynthesis I
PlantCyc:ARA_COMPLETE-ARO-ARA-PWY superpathway of phenylalanine, tyrosine and tryptophan biosynthesis
PlantCyc:ARA_ASPASN-ARA-PWY superpathway of aspartate and asparagine biosynthesis
PlantCyc:ARA_PWY-3481 superpathway of L-phenylalanine and L-tyrosine biosynthesis
PlantCyc:ARA_PWY-3462 L-phenylalanine biosynthesis II
PlantCyc:ARA_PWY-3001 superpathway of L-isoleucine biosynthesis I
PlantCyc:ARA_PWY-3461 L-tyrosine biosynthesis II
PlantCyc:PLANT_PWY-3462 L-phenylalanine biosynthesis II
PlantCyc:PLANT_PWY-3481 superpathway of L-phenylalanine and L-tyrosine biosynthesis
PlantCyc:ARA_ASPARTATESYN-PWY L-aspartate biosynthesis
PlantCyc:PLANT_PWY-3461 L-tyrosine biosynthesis II
PlantCyc:ARA_THRESYN-PWY superpathway of L-threonine biosynthesis
PlantCyc:ARA_MALATE-ASPARTATE-SHUTTLE-PWY L-aspartate degradation II
PlantCyc:ARA_ASPARTATE-DEG1-PWY L-aspartate degradation I
Reactome:R-SSC-8964539 Glutamate and glutamine metabolism
Reactome:R-RNO-8964539 Glutamate and glutamine metabolism
Reactome:R-BTA-8963693 Aspartate and asparagine metabolism
Reactome:R-SCE-8964539 Glutamate and glutamine metabolism
Reactome:R-SSC-8963693 Aspartate and asparagine metabolism
Reactome:R-GGA-8963693 Aspartate and asparagine metabolism
Reactome:R-RNO-8963693 Aspartate and asparagine metabolism
Reactome:R-SPO-8964539 Glutamate and glutamine metabolism
Reactome:R-DDI-8964539 Glutamate and glutamine metabolism
Reactome:R-SCE-8963693 Aspartate and asparagine metabolism
Reactome:R-MMU-8964539 Glutamate and glutamine metabolism
Reactome:R-CEL-8963693 Aspartate and asparagine metabolism
Reactome:R-SPO-8963693 Aspartate and asparagine metabolism
Reactome:R-DDI-8963693 Aspartate and asparagine metabolism
Reactome:R-MMU-8963693 Aspartate and asparagine metabolism
Reactome:R-HSA-8964539 Glutamate and glutamine metabolism
Reactome:R-BTA-8964539 Glutamate and glutamine metabolism
Reactome:R-HSA-8963693 Aspartate and asparagine metabolism
Reactome:R-SSC-9856872 Malate-aspartate shuttle
Reactome:R-HSA-9856872 Malate-aspartate shuttle
Reactome:R-SCE-9856872 Malate-aspartate shuttle
Reactome:R-SPO-9856872 Malate-aspartate shuttle
Reactome:R-DDI-9856872 Malate-aspartate shuttle
Reactome:R-GGA-9856872 Malate-aspartate shuttle
Reactome:R-MMU-9856872 Malate-aspartate shuttle
Reactome:R-RNO-9856872 Malate-aspartate shuttle
Reactome:R-BTA-9856872 Malate-aspartate shuttle
Reactome:R-CEL-9856872 Malate-aspartate shuttle
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-BTA-71291 Amino acid and derivative metabolism
Reactome:R-CEL-611105 Respiratory electron transport
Reactome:R-GGA-1660598 Metabolism
Reactome:R-GGA-352875 Gluconeogenesis
Reactome:R-HSA-611105 Respiratory electron transport
Reactome:R-HSA-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-HSA-1614558 Degradation of cysteine and homocysteine
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-611105 Respiratory electron transport
Reactome:R-MMU-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-RNO-611105 Respiratory electron transport
Reactome:R-RNO-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-SCE-611105 Respiratory electron transport
Reactome:R-SCE-71291 Amino acid and derivative metabolism
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-SPO-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-SSC-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-BTA-611105 Respiratory electron transport
Reactome:R-BTA-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-DDI-71291 Amino acid and derivative metabolism
Reactome:R-DDI-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-GGA-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-GGA-71291 Amino acid and derivative metabolism
Reactome:R-HSA-1237112 Methionine salvage pathway
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SPO-611105 Respiratory electron transport
Reactome:R-SPO-71291 Amino acid and derivative metabolism
Reactome:R-SSC-1430728 Metabolism
Reactome:R-CEL-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-CEL-71291 Amino acid and derivative metabolism
Reactome:R-DDI-611105 Respiratory electron transport
Reactome:R-GGA-1430728 Metabolism
Reactome:R-GGA-353098 Carbohydrate metabolism
Reactome:R-GGA-372568 Amino acid metabolism
Reactome:R-HSA-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-MMU-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-RNO-71291 Amino acid and derivative metabolism
Reactome:R-SCE-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-SCE-389661 Glyoxylate metabolism and glycine degradation
Reactome:R-SSC-611105 Respiratory electron transport
Reactome:R-SSC-71291 Amino acid and derivative metabolism
Reactome:R-CEL-1430728 Metabolism
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DDI-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-GGA-611105 Respiratory electron transport
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-1614635 Sulfur amino acid metabolism
Reactome:R-SSC-1428517 Aerobic respiration and respiratory electron transport
WikiPathways:WP4595 Urea cycle and associated pathways
WikiPathways:WP5166 Glyoxylate metabolism
WikiPathways:WP465 Tryptophan metabolism
WikiPathways:WP4583 Biomarkers for urea cycle disorders
WikiPathways:WP5220 Metabolic reprogramming in pancreatic cancer
WikiPathways:WP4504 Cysteine and methionine catabolism
PathBank:SMP0120654 Cystinosis, Ocular Nonnephropathic
PathBank:SMP0120666 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0120682 Carbamoyl Phosphate Synthetase Deficiency
PathBank:SMP0120686 Citrullinemia Type I
PathBank:SMP0120714 Homocarnosinosis
PathBank:SMP0120762 Ornithine Transcarbamylase Deficiency (OTC Deficiency)
PathBank:SMP0120850 Succinic Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0120456 Argininosuccinic Aciduria
PathBank:SMP0120496 Hyperinsulinism-Hyperammonemia Syndrome
PathBank:SMP0120540 Phenylketonuria
PathBank:SMP0120569 Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency
PathBank:SMP0000059 Urea Cycle
PathBank:SMP0000020 Arginine and Proline Metabolism
PathBank:SMP0000129 Malate-Aspartate Shuttle
PathBank:SMP0000339 Hyperinsulinism-Hyperammonemia Syndrome
PathBank:SMP0000362 Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)
PathBank:SMP0000188 Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)
PathBank:SMP0000369 Tyrosinemia Type 2 (or Richner-Hanhart Syndrome)
PathBank:SMP0000190 Hawkinsinuria
PathBank:SMP0000001 Citrullinemia Type I
PathBank:SMP0000504 Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency
PathBank:SMP0000722 Cystinosis, Ocular Nonnephropathic
PathBank:SMP0002302 Aspartate Metabolism
PathBank:SMP0002442 Phenylalanine Metabolism
PathBank:SMP0002457 Tyrosine Metabolism
PathBank:SMP0087278 Glutamate Metabolism
PathBank:SMP0087438 Malate-Aspartate Shuttle
PathBank:SMP0087450 Tyrosine Metabolism
PathBank:SMP0063596 Arginine and Proline Metabolism
PathBank:SMP0120677 Argininosuccinic Aciduria
PathBank:SMP0108760 Glutaminolysis and Cancer
PathBank:SMP0120455 Argininemia
PathBank:SMP0120491 Hawkinsinuria
PathBank:SMP0120499 Hyperprolinemia Type I
PathBank:SMP0120511 Tyrosinemia Type 3 (TYRO3)
PathBank:SMP0120539 Prolinemia Type II
PathBank:SMP0120564 beta-Mercaptolactate-Cysteine Disulfiduria
PathBank:SMP0120572 L-Arginine:Glycine Amidinotransferase Deficiency
PathBank:SMP0000385 Homocarnosinosis
PathBank:SMP0000207 Prolidase Deficiency (PD)
PathBank:SMP0000208 Prolinemia Type II
PathBank:SMP0000206 Phenylketonuria
PathBank:SMP0000169 Alkaptonuria
PathBank:SMP0000003 Argininosuccinic Aciduria
PathBank:SMP0000136 2-Hydroxyglutric Aciduria (D and L Form)
PathBank:SMP0000429 Disulfiram Action Pathway
PathBank:SMP0000499 beta-Mercaptolactate-Cysteine Disulfiduria
PathBank:SMP0000507 L-Arginine:Glycine Amidinotransferase Deficiency
PathBank:SMP0000567 Succinic Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0087301 Malate-Aspartate Shuttle
PathBank:SMP0063474 Tropane, Piperidine, and Pyridine Alkaloid Biosynthesis
PathBank:SMP0063607 Cysteine Metabolism
PathBank:SMP0063684 Tyrosine Metabolism
PathBank:SMP0120676 Argininemia
PathBank:SMP0120716 Hyperinsulinism-Hyperammonemia Syndrome
PathBank:SMP0108773 Glutaminolysis and Cancer
PathBank:SMP0120445 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0120453 Alkaptonuria
PathBank:SMP0120501 Hyperprolinemia Type II
PathBank:SMP0120509 Tyrosinemia Type I
PathBank:SMP0120513 Tyrosinemia Type 2 (or Richner-Hanhart Syndrome)
PathBank:SMP0120541 Prolidase Deficiency (PD)
PathBank:SMP0120570 Hyperornithinemia with Gyrate Atrophy (HOGA)
PathBank:SMP0120598 Monoamine Oxidase-A Deficiency (MAO-A)
PathBank:SMP0000013 Cysteine Metabolism
PathBank:SMP0000360 Hyperprolinemia Type II
PathBank:SMP0000363 Ornithine Aminotransferase Deficiency (OAT Deficiency)
PathBank:SMP0000370 Tyrosinemia Type 3 (TYRO3)
PathBank:SMP0000218 Tyrosinemia Type I
PathBank:SMP0000205 Ornithine Transcarbamylase Deficiency (OTC Deficiency)
PathBank:SMP0000505 Hyperornithinemia with Gyrate Atrophy (HOGA)
PathBank:SMP0000533 Monoamine Oxidase-A Deficiency (MAO-A)
PathBank:SMP0087428 Glutamate Metabolism
PathBank:SMP0063590 Glutamate Metabolism
PathBank:SMP0063636 Malate-Aspartate Shuttle
PathBank:SMP0120659 2-Hydroxyglutric Aciduria (D and L Form)
PathBank:SMP0120438 2-Hydroxyglutric Aciduria (D and L Form)
PathBank:SMP0120454 Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)
PathBank:SMP0120462 Carbamoyl Phosphate Synthetase Deficiency
PathBank:SMP0120466 Citrullinemia Type I
PathBank:SMP0120490 Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)
PathBank:SMP0120494 Homocarnosinosis
PathBank:SMP0120538 Ornithine Aminotransferase Deficiency (OAT Deficiency)
PathBank:SMP0120542 Ornithine Transcarbamylase Deficiency (OTC Deficiency)
PathBank:SMP0120559 Tyrosinemia, Transient, of the Newborn
PathBank:SMP0120563 Dopamine beta-Hydroxylase Deficiency
PathBank:SMP0120571 Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]
PathBank:SMP0120631 Succinic Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0000072 Glutamate Metabolism
PathBank:SMP0000006 Tyrosine Metabolism
PathBank:SMP0000008 Phenylalanine and Tyrosine Metabolism
PathBank:SMP0000243 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0000361 Hyperprolinemia Type I
PathBank:SMP0000357 Argininemia
PathBank:SMP0000002 Carbamoyl Phosphate Synthetase Deficiency
PathBank:SMP0000494 Tyrosinemia, Transient, of the Newborn
PathBank:SMP0000498 Dopamine beta-Hydroxylase Deficiency
PathBank:SMP0000506 Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]
PathBank:SMP0002206 Asparagine Metabolism
PathBank:SMP0002298 Glutaminolysis and Cancer
PathBank:SMP0002422 Aspartate Metabolism
PathBank:SMP0002444 Threonine Metabolism
PathBank:SMP0087319 Urea Cycle
PathBank:SMP0063471 Isoquinoline Alkaloid Biosynthesis
PathBank:SMP0063649 Phenylalanine and Tyrosine Metabolism
PathBank:SMP0063686 Urea Cycle