Glutamate and glutamine metabolism
Häussinger D. Liver glutamine metabolism. JPEN J Parenter Enteral Nutr. 1990 Jul;14(4 Suppl):56S–62S. doi: 10.1177/014860719001400405. PMID: 2205732.; Owen OE, Reichard GA, Patel MS, Boden G. Energy metabolism in feasting and fasting. Adv Exp Med Biol. 1979;111():169–88. doi: 10.1007/978-1-4757-0734-2_8. PMID: 371355.; Felig P. Amino acid metabolism in man. Annu Rev Biochem. 1975;44():933–55. doi: 10.1146/annurev.bi.44.070175.004441. PMID: 1094924.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.4.1.3 | glutamate dehydrogenase [NAD(P)+] | L-glutamate:NAD(P)+ oxidoreductase (deaminating) | |
| 1.5.1.2 | pyrroline-5-carboxylate reductase | L-proline:NAD(P)+ 5-oxidoreductase | |
| 2.3.1.225 | protein S-acyltransferase | palmitoyl-CoA:[protein]-L-cysteine S-palmitoyltransferase | |
| 2.6.1.1 | aspartate transaminase | L-aspartate:2-oxoglutarate aminotransferase | |
| 2.6.1.13 | ornithine aminotransferase | L-ornithine:2-oxo-acid aminotransferase | |
| 2.6.1.64 | glutamine-phenylpyruvate transaminase | L-glutamine:phenylpyruvate aminotransferase | |
| 2.6.1.7 | kynurenine-oxoglutarate transaminase | L-kynurenine:2-oxoglutarate aminotransferase | |
| 3.5.1.2 | glutaminase | L-glutamine amidohydrolase | |
| 4.4.1.13 | cysteine-S-conjugate beta-lyase | L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming) | |
| 6.3.1.2 | glutamine synthetase | L-glutamate:ammonia ligase (ADP-forming) |
Proteins
| Protein ID | name | full name |
|---|