KEGG:R00014
2-oxoglutarate dehydrogenase complex: pyruvate dehydrogenase (see R01699), subsequently R03270
pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)
Pyruvate[C3H4O3] + Thiamin diphosphate[C12H19N4O7P2S] = 2-(alpha-Hydroxyethyl)thiamine diphosphate[C14H23N4O8P2S] + CO2[CO2]
DB Links
Alias
Metabolites
Substrates
| metabolite | compartment | Structure |
|---|---|---|
| Pyruvate Formula: C3H4O3 |
Cytoplasm | |
| Thiamin diphosphate Formula: C12H19N4O7P2S |
Cytoplasm |
Products
| metabolite | compartment | Structure |
|---|---|---|
| 2-(alpha-Hydroxyethyl)thiamine diphosphate Formula: C14H23N4O8P2S |
Cytoplasm | |
| CO2 Formula: CO2 |
Cytoplasm |