POT1 - Saccharomyces cerevisiae S288C

3-ketoacyl-CoA thiolase, peroxisomal

3D-structure Acyltransferase Fatty acid metabolism Lipid metabolism Mitochondrion Peroxisome Reference proteome Transferase Transit peptide

Peroxisome Mitochondrion intermembrane space
> POT1 - Saccharomyces cerevisiae S288C [3-ketoacyl-CoA thiolase, peroxisomal]
请在左侧输入序列并点击“更新视图”...



统计信息
序列长度 0
疏水性残基 0
极性残基 0
Legend

Metadata

Organism Source: 559292 - Saccharomyces cerevisiae S288C
EC Number: 2.3.1.16
Cluster:
Registry Model:

Reactions

reaction id name note
KEGG:R00238 acetyl-CoA:acetyl-CoA C-acetyltransferase 2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
KEGG:R00391 acyl-CoA:acetyl-CoA C-acyltransferase general reaction
KEGG:R00829 succinyl-CoA:acetyl-CoA C-acyltransferase; Succinyl-CoA + Acetyl-CoA <=> CoA + 3-Oxoadipyl-CoA
KEGG:R00927 acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA
KEGG:R01177 butanoyl-CoA:acetyl-CoA C-butanoyltransferase Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
KEGG:R03778 octanoyl-CoA:acetyl-CoA C-acyltransferase Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA
KEGG:R03858 lauroyl-CoA:acetyl-CoA C-acyltransferase Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA
KEGG:R03991 myristoyl-CoA:acetylCoA C-myristoyltransferase Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA
KEGG:R04742 decanoyl-CoA:acetyl-CoA C-acyltransferase Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA
KEGG:R04747 hexanoyl-CoA:acetyl-CoA C-acyltransferase Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA
KEGG:R05506 C07118 + C00010<=>C00512 + C00024 benzoyl acetyl-CoA thiolase
KEGG:R05586 C06715 + C00010<=>C00527 + C00024 3-Oxopimeloyl-CoA + CoA <=> Glutaryl-CoA + Acetyl-CoA
KEGG:R07891 C16331 + C00024<=>C00010 + C16330 OPC6-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC8-CoA
KEGG:R07895 C16335 + C00024<=>C00010 + C16334 OPC4-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC6-CoA
KEGG:R07899 C16339 + C00024<=>C00010 + C16338 (+)-7-Isojasmonic acid CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC4-CoA
KEGG:R07937 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA:acetyl-CoA C-acyltransferase (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexaenoyl-CoA
KEGG:R07953 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA:acetyl-CoA C-acyltransferase (4Z,7Z,10Z,13Z,16Z)-Docosapentaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapentaenoyl-CoA
KEGG:R08091 7-methyl-3-oxo-6-octenoyl-CoA:acetyl-CoA C-acyltransferase 7-Methyl-3-oxo-6-octenoyl-CoA + CoA <=> 5-Methylhex-4-enoyl-CoA + Acetyl-CoA
KEGG:R08095 3-methylcrotonyl-CoA:acetyl-CoA C-acyltransferase 5-Methyl-3-oxo-4-hexenoyl-CoA + CoA <=> 3-Methylcrotonyl-CoA + Acetyl-CoA
KEGG:R13467 3-oxochol-4-en-24-oyl-CoA:propanoyl-CoA C-acyltransferase 3,24-Dioxocholest-4-en-26-oyl-CoA + CoA <=> 3-Oxochol-4-en-24-oyl-CoA + Propanoyl-CoA
KEGG:R13471 3-oxopregnene-20-carboxyl-CoA:acetyl-CoA C-acyltransferase 3,22-Dioxochol-4-en-24-oyl-CoA + CoA <=> 3-Oxopregnene-20-carboxyl-CoA + Acetyl-CoA
KEGG:R13479 3-oxoacyl-CoA thiolase 3-[(3aS,4S,5R,7aS)-5-Hydroxy-7a-methyl-1-oxooctahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA + CoA <=> (3aS,4S,5R,7aS)-5-Hydroxy-7a-methyl-1-oxooctahydro-1H-indene-4-carboxyl-CoA + Acetyl-CoA
KEGG:R13483 MOODA-CoA:acetyl-CoA C-acyltransferase 9-Carboxy-6-methyl-3,7-dioxononanoyl-CoA + CoA <=> 7-Carboxy-4-methyl-5-oxoheptanoyl-CoA + Acetyl-CoA
BioCyc:ACETYL-COA-ACETYLTRANSFER-RXN 2 ACETYL-COA<=>ACETOACETYL-COA + CO-A
BioCyc:RXN-12565 BUTYRYL-COA + ACETYL-COA<=>K-HEXANOYL-COA + CO-A
BioCyc:RXN-17791 CO-A + CPD-19158 --> ACETYL-COA + CPD-19147
BioCyc:RXN-13617 CPD-196 + ACETYL-COA<=>CPD0-2123 + CO-A
BioCyc:RXN-17787 ACETYL-COA + CPD-10269<=>CO-A + CPD-19160
BioCyc:RXN-17799 CPD-19153 + CO-A --> ACETYL-COA + CPD-14925
BioCyc:RXN-14277 hexanoyl-CoA C-acyltransferase
BioCyc:RXN-17795 CPD-19157 + CO-A --> ACETYL-COA + CPD-19148
BioCyc:RXN-14274 decanoyl-CoA C-acyltransferase
BioCyc:RXN-17782 CPD-19167 + CO-A --> CPD-15436 + ACETYL-COA
BioCyc:RXN-14394 CPD-7221 + ACETYL-COA<=>CPD-15244 + CO-A
BioCyc:RXN-17778 CPD-19169 + CO-A --> CPD-19144 + ACETYL-COA
BioCyc:KETOACYLCOATHIOL-RXN 3-KETOACYL-COA + CO-A --> Saturated-Fatty-Acyl-CoA + ACETYL-COA The final reaction in the β-oxidation cycle, releases product acetyl CoA and an acyl CoA fatty acid two carbons shorter, ready to go through β-oxidation reactions again.
Rhea:RHEA:21565 an acyl-CoA + acetyl-CoA => a 3-oxoacyl-CoA + CoA
Rhea:RHEA:21566 a 3-oxoacyl-CoA + CoA => an acyl-CoA + acetyl-CoA
Rhea:RHEA:21567 an acyl-CoA + acetyl-CoA <=> a 3-oxoacyl-CoA + CoA
BioCyc:RXN-10700 CPD-11524 + CO-A --> CPD-11525 + ACETYL-COA
BioCyc:RXN-21785 Short-Chain-2-Methyl-3-oxoacyl-CoAs + CO-A --> Short-Chain-2-Me-Fatty-Acyl-CoA + PROPIONYL-COA
BioCyc:RXN-21225 CPD-22850 + CO-A --> CPD-22847 + ACETYL-COA
BioCyc:RXN-14268 lauroyl-CoA acetyl-CoA acyltransferase
BioCyc:RXN-14788 CPD-15676 + CO-A --> CPD-15677 + ACETYL-COA
BioCyc:RXN-19804 CPD-21419 + CO-A --> CPD-21420 + ACETYL-COA
BioCyc:RXN-11246 CPD-10600 + CO-A --> CPD-201 + ACETYL-COA
BioCyc:RXN-12561 ACETYL-COA + PROPIONYL-COA<=>CPD-13534 + CO-A
BioCyc:RXN-19800 CPD-21415 + CO-A --> CPD-21416 + ACETYL-COA
BioCyc:RXN-12751 CPD-13758 + CO-A --> CPD-21411 + ACETYL-COA
BioCyc:RXN-10701 CPD-11528 + CO-A --> CPD-11529 + ACETYL-COA
BioCyc:RXN-17116 CPD-18494 + CO-A --> CPD-17365 + ACETYL-COA
BioCyc:RXN-20153 3-Oxoacyl-CoAs + CO-A --> ACYL-COA + ACETYL-COA
BioCyc:RXN-21786 Medium-Chain-2-Methyl-3-oxoacyl-CoAs + CO-A --> Medium-Chain-2-Me-Fatty-Acyl-CoA + PROPIONYL-COA
BioCyc:RXN-16137 CPD-17388 + CO-A --> CPD-17312 + ACETYL-COA
BioCyc:RXN-14799 CPD-15687 + CO-A --> CPD-15688 + ACETYL-COA
BioCyc:METHYLACETOACETYLCOATHIOL-RXN 2-METHYL-ACETO-ACETYL-COA + CO-A<=>PROPIONYL-COA + ACETYL-COA
BioCyc:RXN-21787 Long-Chain-2-Methyl-3-oxoacyl-CoAs + CO-A --> Long-Chain-2-Me-Fatty-Acyl-CoA + PROPIONYL-COA
BioCyc:RXN-12710 CPD-13699 + CO-A --> CPD-13700 + ACETYL-COA
BioCyc:RXN-10699 CPD-11520 + CO-A --> CPD-11521 + ACETYL-COA
BioCyc:RXN-21768 CPD-23633 + CO-A --> PENTANOYLCOA-CPD + PROPIONYL-COA
BioCyc:RXN-14793 CPD-15678 + CO-A --> CPD-15663 + ACETYL-COA
BioCyc:RXN-14774 CPD-15667 + CO-A --> CPD-15668 + ACETYL-COA
BioCyc:RXN-21761 CPD-23613 + CO-A --> CPD-23574 + PROPIONYL-COA
BioCyc:RXN-14803 CPD-15691 + CO-A --> CPD-15692 + ACETYL-COA
BioCyc:RXN-21757 2-Methyl-3-oxoacyl-CoAs + CO-A --> Saturated-Fatty-Acyl-CoA + PROPIONYL-COA

Pathways

pathway id name
BioCyc:META_PWY-7339 10-trans-heptadecenoyl-CoA degradation (MFE-dependent, yeast)
BioCyc:META_PWY-7338 10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)
BioCyc:YEAST_PWY-7288 fatty acid β-oxidation (peroxisome)
BioCyc:META_PWY-7340 9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)
BioCyc:META_PWY-7337 10-cis-heptadecenoyl-CoA degradation (yeast)
BioCyc:YEAST_PWY-7338 10-trans-heptadecenoyl-CoA degradation (reductase-dependent)
BioCyc:YEAST_PWY-7339 10-trans-heptadecenoyl-CoA degradation (MFE-dependent)
BioCyc:META_PWY-7288 fatty acid β-oxidation (peroxisome, yeast)
BioCyc:YEAST_PWY-7337 10-cis-heptadecenoyl-CoA degradation
BioCyc:YEAST_YEAST-FAO-PWY fatty acid oxidation (non-cyclic)
BioCyc:YEAST_PWY-7340 9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent)
Reactome:R-SCE-2046106 alpha-linolenic acid (ALA) metabolism
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-8978868 Fatty acid metabolism
Reactome:R-SCE-2046104 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Reactome:R-SCE-390918 Peroxisomal lipid metabolism
Reactome:R-SCE-556833 Metabolism of lipids
Reactome:R-SCE-390247 Beta-oxidation of very long chain fatty acids
PathBank:SMP0002361 Fatty Acid Metabolism
PathBank:SMP0002368 Fatty Acid Elongation In Mitochondria
PathBank:SMP0002381 Steroid Biosynthesis
PathBank:SMP0002383 Ketone Body Metabolism
PathBank:SMP0002384 Terpenoid Backbone Biosynthesis