superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.17.4.1 | ribonucleoside-diphosphate reductase | 2'-deoxyribonucleoside-5'-diphosphate:thioredoxin-disulfide 2'-oxidoreductase | |
| 2.1.1.45 | thymidylate synthase | 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase | |
| 2.1.3.2 | aspartate carbamoyltransferase | carbamoyl-phosphate:L-aspartate carbamoyltransferase | |
| 2.7.4.22 | UMP kinase | ATP:UMP phosphotransferase | |
| 2.7.4.6 | nucleoside-diphosphate kinase | ATP:nucleoside-diphosphate phosphotransferase | |
| 3.6.1.23 | dUTP diphosphatase | dUTP nucleotidohydrolase | |
| 4.1.1.23 | orotidine-5'-phosphate decarboxylase | orotidine-5'-phosphate carboxy-lyase (UMP-forming) | |
| 6.3.4.16 | carbamoyl-phosphate synthase (ammonia) | carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating) | |
| 6.3.5.5 | carbamoyl-phosphate synthase (glutamine-hydrolysing) | hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| P58638 | pyrF | Orotidine 5'-phosphate decarboxylase |
| Q8UDE9 | carB | Carbamoyl phosphate synthase large chain |
| Q8UDF7 | carA | Carbamoyl phosphate synthase small chain |
| Q8UDS3 | thyA | Thymidylate synthase |
| Q8UEM4 | nrdJ | Vitamin B12-dependent ribonucleotide reductase |
| Q8UFM1 | pyrH | Uridylate kinase |
| Q8UFT9 | pyrB | Aspartate carbamoyltransferase catalytic subunit |
| Q8UGB6 | ndk | Nucleoside diphosphate kinase |
| Q8UII1 | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase |