EC: 6.4.1.1

pyruvate carboxylase (pyruvate:carbon-dioxide ligase (ADP-forming))

enzyme lambda metabolic reaction experiment
uniprot:Q05FZ3 [pyruvate carboxylase(Enzyme) wildtype]

Pyruvate + Hydrogencarbonate + ATP -> ADP + Oxaloacetate + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris/HCl, 5 mM MgCl2, 100 mM KCl, 0.1 mM acetyl-CoA, 0.15 mM NADH
PH: 8
Temperature: 30
uniprot:Q05FZ3 [pyruvate carboxylase(Enzyme) wildtype]

ATP + Pyruvate + Hydrogencarbonate -> Phosphate + ADP + Oxaloacetate		 (( (Vmax * A) ) / (( (Km + A) ) + (( (A ^ 2) ) / Ki))) buffer: 100 mM Tris/HCl, 5 mM MgCl2, 100 mM KCl, 0.1 mM acetyl-CoA, 0.15 mM NADH
PH: 8
Temperature: 30
uniprot:Q05FZ3 [pyruvate carboxylase(Enzyme) wildtype]

Pyruvate + ATP + Hydrogencarbonate -> Oxaloacetate + Phosphate + ADP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris/HCl, 5 mM MgCl2, 100 mM KCl, 0.1 mM acetyl-CoA, 0.15 mM NADH
PH: 8
Temperature: 30
uniprot:Q05FZ3 [pyruvate carboxylase(Enzyme) wildtype]

Pyruvate + Hydrogencarbonate + ATP -> Phosphate + Oxaloacetate + ADP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris/HCl, 5 mM MgCl2, 100 mM KCl, 0.1 mM acetyl-CoA, 0.15 mM NADH
PH: 8
Temperature: 30
uniprot:Q05FZ3 [Biotin]

Holo_[carboxylase] + ATP + Hydrogencarbonate -> Phosphate + Carboxybiotin_carboxyl_carrier_protein + ADP		 (( (Vmax * A) ) / (( (Km + A) ) + (( (A ^ 2) ) / Ki))) buffer: 100 mM Tris/HCl, 5 mM MgCl2, 100 mM KCl, 0.1 mM acetyl-CoA, 0.5 mM phosphoenol pyruvate, 0.15 mM NADH
PH: 8
Temperature: 30
uniprot:Q05FZ3 [Biotin]

Hydrogencarbonate + ATP + Holo_[carboxylase] -> Carboxybiotin_carboxyl_carrier_protein + ADP + Phosphate		 (( (Vmax * A) ) / (( (Km + A) ) + v0)) buffer: 100 mM Tris/HCl, 5 mM MgCl2, 100 mM KCl, 0.1 mM acetyl-CoA, 0.5 mM phosphoenol pyruvate, 0.15 mM NADH
PH: 8
Temperature: 30
uniprot:Q05FZ3 [Biotin]

ATP + Holo_[carboxylase] + Hydrogencarbonate -> Carboxybiotin_carboxyl_carrier_protein + ADP + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris/HCl, 5 mM MgCl2, 100 mM KCl, 0.1 mM acetyl-CoA, 0.5 mM phosphoenol pyruvate, 0.15 mM NADH
PH: 8
Temperature: 30
uniprot:Q05FZ3 [Biotin]

Hydrogencarbonate + ATP + Holo_[carboxylase] -> ADP + Phosphate + Carboxybiotin_carboxyl_carrier_protein		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris/HCl, 5 mM MgCl2, 100 mM KCl, 0.1 mM acetyl-CoA, 0.5 mM phosphoenol pyruvate, 0.15 mM NADH
PH: 8
Temperature: 30
uniprot:P11154 [Acetyl-CoA]

ATP + Pyruvate + Hydrogencarbonate -> Phosphate + Oxaloacetate + ADP		 (( (( (E * Kcat) ) / (1 + (K_k / K))) ) + (E * Kcat0)) buffer: 0.1 M Tris-HCl, 7 mM MgCl2, 0.21 mM NADH
PH: 7.8
Temperature: 30
uniprot:P11154 [Acetyl-CoA]

ATP + Pyruvate + Hydrogencarbonate -> ADP + Phosphate + Oxaloacetate		 (( (( (E * Kcat) ) / (1 + (K_k / K))) ) + (E * Kcat0)) buffer: 0.1 M Tris-HCl, 7 mM MgCl2, 0.21 mM NADH
PH: 7.8
Temperature: 30
uniprot:P11154 [Acetyl-CoA]

Pyruvate + ATP + Hydrogencarbonate -> ADP + Oxaloacetate + Phosphate		 (( (( (E * Kcat) ) * C) ) / (Km_C + C)) buffer: 0.1 M Tris-HCl, 7 mM MgCl2, 0.21 mM NADH
PH: 7.8
Temperature: 30
uniprot:P11154 [Acetyl-CoA]

Pyruvate + ATP + Hydrogencarbonate -> Oxaloacetate + Phosphate + ADP		 (( (( (E * Kcat) ) * A) ) / (Km_A + A)) buffer: 0.1 M Tris-HCl, 7 mM MgCl2, 0.21 mM NADH
PH: 7.8
Temperature: 30
uniprot:P11154 [Acetyl-CoA]

ATP + Pyruvate + Hydrogencarbonate -> ADP + Oxaloacetate + Phosphate		 (( (( (E * Kcat) ) * B) ) / (Km_B + B)) buffer: 0.1 M Tris-HCl, 7 mM MgCl2, 0.21 mM NADH
PH: 7.8
Temperature: 30
uniprot:P11154 [K+]

Pyruvate + ATP + Hydrogencarbonate -> ADP + Oxaloacetate + Phosphate		 (( (( (E * Kcat) ) / (1 + (K_k / K))) ) + (E * Kcat0)) buffer: 0.1 M Tris-HCl, 7 mM MgCl2, 0.21 mM NADH
PH: 7.8
Temperature: 30
uniprot:P11154 [K+]

Hydrogencarbonate + Pyruvate + ATP -> Phosphate + Oxaloacetate + ADP		 (( (( (E * Kcat) ) / (1 + (K_k / K))) ) + (E * Kcat0)) buffer: 0.1 M Tris-HCl, 7 mM MgCl2, 0.21 mM NADH
PH: 7.8
Temperature: 30
uniprot:P11154 [Acetyl-CoA]

ATP + Pyruvate + Hydrogencarbonate -> ADP + Phosphate + Oxaloacetate		 (( (( (E * Kcat) ) * B) ) / (Km_B + B)) buffer: 0.1 M Tris-HCl, 7 mM MgCl2, 0.21 mM NADH
PH: 7.8
Temperature: 30
uniprot:P11154 [Acetyl-CoA]

ATP + Hydrogencarbonate + Pyruvate -> Phosphate + Oxaloacetate + ADP		 (( (( (E * Kcat) ) * A) ) / (Km_A + A)) buffer: 0.1 M Tris-HCl, 7 mM MgCl2, 0.21 mM NADH
PH: 7.8
Temperature: 30
uniprot:P11154 [Acetyl-CoA]

Pyruvate + Hydrogencarbonate + ATP -> Oxaloacetate + Phosphate + ADP		 (( (( (E * Kcat) ) * C) ) / (Km_C + C)) buffer: 0.1 M Tris-HCl, 7 mM MgCl2, 0.21 mM NADH
PH: 7.8
Temperature: 30
- [Mg2+]

ATP + Hydrogencarbonate + Pyruvate -> Phosphate + ADP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM TEA-HCl, 0.15 mM NADH, 0.1 mM Acetyl-CoA, 0.5 IU malate dehydrogenase
PH: 8
Temperature: 37
- [Mg2+]

Hydrogencarbonate + Pyruvate + ATP -> Oxaloacetate + ADP + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM TEA-HCl, 0.15 mM NADH, 0.1 mM Acetyl-CoA, 0.5 IU malate dehydrogenase
PH: 8
Temperature: 37
- [Mg2+]

Hydrogencarbonate + ATP + Pyruvate -> ADP + Phosphate + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM TEA-HCl, 0.15 mM NADH, 0.1 mM Acetyl-CoA, 0.5 IU malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P11498 [pyruvate carboxylase(Enzyme) wildtype]

Pyruvate + ATP + Hydrogencarbonate -> Oxaloacetate + Phosphate + ADP		 (( (V * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, 10 mM MgCl2
PH: 7.4
Temperature: 30
uniprot:P11498 [pyruvate carboxylase(Enzyme) wildtype]

Hydrogencarbonate + Pyruvate + ATP -> Oxaloacetate + Phosphate + ADP		 (( (V * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, 10 mM MgCl2
PH: 7.4
Temperature: 30
uniprot:P11498 [pyruvate carboxylase(Enzyme) mutant A610T]

Pyruvate + Hydrogencarbonate + ATP -> Phosphate + ADP + Oxaloacetate		 (( (V * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, 10 mM MgCl2
PH: 7.4
Temperature: 30
uniprot:P11498 [pyruvate carboxylase(Enzyme) mutant A610T]

Hydrogencarbonate + ATP + Pyruvate -> Phosphate + ADP + Oxaloacetate		 (( (V * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, 10 mM MgCl2
PH: 7.4
Temperature: 30
- [pyruvate carboxylase(Enzyme) mutant E576Q]

Pyruvate + Hydrogencarbonate + ATP -> ADP + Phosphate + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30
- [pyruvate carboxylase(Enzyme) mutant D649N]

Hydrogencarbonate + Pyruvate + ATP -> Oxaloacetate + ADP + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30
- [pyruvate carboxylase(Enzyme) wildtype]

ATP + Hydrogencarbonate + Pyruvate -> Phosphate + Oxaloacetate + ADP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30
- [pyruvate carboxylase(Enzyme) mutant D543E]

Hydrogencarbonate + ATP + Pyruvate -> Phosphate + ADP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30
- [pyruvate carboxylase(Enzyme) mutant K712R]

Pyruvate + Hydrogencarbonate + ATP -> ADP + Oxaloacetate + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30
- [pyruvate carboxylase(Enzyme) mutant E576D]

Hydrogencarbonate + ATP + Pyruvate -> Oxaloacetate + ADP + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30
- [pyruvate carboxylase(Enzyme) mutant D713E]

ATP + Hydrogencarbonate + Pyruvate -> Oxaloacetate + ADP + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30
- [pyruvate carboxylase(Enzyme) mutant E592Q]

Pyruvate + Hydrogencarbonate + ATP -> Oxaloacetate + ADP + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30
- [Oxamate]

Oxaloacetate + ADP + Phosphate -> ATP + Hydrogencarbonate + Pyruvate		 (( (( (Vmax * A) ) / (( (A + Km) ) + (( (A ^ 2) ) / Ki))) ) + vo) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Lactate dehydrogenase
PH: 8
Temperature: 30
- [Oxamate]

Phosphate + Oxaloacetate + ADP -> Hydrogencarbonate + ATP + Pyruvate		 (( (( (Vmax * A) ) / (( (A + Km) ) + (( (A ^ 2) ) / Ki))) ) + vo) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Lactate dehydrogenase
PH: 8
Temperature: 30
- [Oxamate]

Phosphate + ADP + Oxaloacetate -> Pyruvate + ATP + Hydrogencarbonate		 (( (( (Vmax * A) ) / (( (A + Km) ) + (( (A ^ 2) ) / Ki))) ) + vo) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Lactate dehydrogenase
PH: 8
Temperature: 30
- [Oxamate]

Oxaloacetate + Phosphate + ADP -> Hydrogencarbonate + ATP + Pyruvate		 (( (Vmax * A) ) / (( (A + Km) ) + (( (A ^ 2) ) / Ki))) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Lactate dehydrogenase
PH: 8
Temperature: 30
- [Oxamate]

Oxaloacetate + ADP + Phosphate -> Hydrogencarbonate + Pyruvate + ATP		 (( (Vmax * A) ) / (( (A + Km) ) + (( (A ^ 2) ) / Ki))) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Lactate dehydrogenase
PH: 8
Temperature: 30
- [Oxamate]

Phosphate + Oxaloacetate + ADP -> Hydrogencarbonate + ATP + Pyruvate		 (( (Vmax * A) ) / (( (A + Km) ) + (( (A ^ 2) ) / Ki))) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Lactate dehydrogenase
PH: 8
Temperature: 30
- [pyruvate carboxylase(Enzyme) mutant D762N]

ATP + Pyruvate + Hydrogencarbonate -> Phosphate + ADP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30
- [pyruvate carboxylase(Enzyme) mutant D713N]

ATP + Hydrogencarbonate + Pyruvate -> Oxaloacetate + Phosphate + ADP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30
- [pyruvate carboxylase(Enzyme) mutant D762E]

ATP + Pyruvate + Hydrogencarbonate -> Oxaloacetate + ADP + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 0.1 mM Acetyl-CoA, 5 mM MgCl2, 100 mM KCl, 0.15 mM NADH, 5 units/ml Malate dehydrogenase
PH: 8
Temperature: 30

Pathways

pathway id name
BioCyc:YEAST_ASPBIO-PWY aspartate biosynthesis
BioCyc:HUMAN_PWY66-399 gluconeogenesis
BioCyc:META_PWY-6142 gluconeogenesis II (Methanobacterium thermoautotrophicum)
BioCyc:META_PWY66-399 gluconeogenesis III
BioCyc:META_PWY-6146 Methanobacterium thermoautotrophicum biosynthetic metabolism
BioCyc:YEAST_GLUCONEO-YEAST-PWY gluconeogenesis
BioCyc:MOUSE_ASPBIO-PWY aspartate biosynthesis
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-CEL-70263 Gluconeogenesis
Reactome:R-HSA-70263 Gluconeogenesis
Reactome:R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-HSA-196780 Biotin transport and metabolism
Reactome:R-HSA-1643685 Disease
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-MMU-196780 Biotin transport and metabolism
Reactome:R-RNO-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-RNO-196780 Biotin transport and metabolism
Reactome:R-SCE-71387 Carbohydrate metabolism
Reactome:R-SCE-70326 Glucose metabolism
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-BTA-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-BTA-196780 Biotin transport and metabolism
Reactome:R-CEL-71387 Carbohydrate metabolism
Reactome:R-CEL-70326 Glucose metabolism
Reactome:R-CEL-70268 Pyruvate metabolism
Reactome:R-CEL-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-CEL-196780 Biotin transport and metabolism
Reactome:R-HSA-71387 Carbohydrate metabolism
Reactome:R-HSA-70326 Glucose metabolism
Reactome:R-HSA-70268 Pyruvate metabolism
Reactome:R-HSA-196854 Metabolism of vitamins and cofactors
Reactome:R-HSA-3296482 Defects in vitamin and cofactor metabolism
Reactome:R-HSA-3371599 Defective HLCS causes multiple carboxylase deficiency
Reactome:R-MMU-70268 Pyruvate metabolism
Reactome:R-MMU-196854 Metabolism of vitamins and cofactors
Reactome:R-RNO-70263 Gluconeogenesis
Reactome:R-RNO-70268 Pyruvate metabolism
Reactome:R-RNO-196854 Metabolism of vitamins and cofactors
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-70268 Pyruvate metabolism
Reactome:R-SCE-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-SCE-196780 Biotin transport and metabolism
Reactome:R-BTA-71387 Carbohydrate metabolism
Reactome:R-BTA-70326 Glucose metabolism
Reactome:R-CEL-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-HSA-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-HSA-5668914 Diseases of metabolism
Reactome:R-MMU-71387 Carbohydrate metabolism
Reactome:R-MMU-70326 Glucose metabolism
Reactome:R-MMU-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-SCE-70263 Gluconeogenesis
Reactome:R-SCE-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-SPO-71387 Carbohydrate metabolism
Reactome:R-SPO-70326 Glucose metabolism
Reactome:R-SPO-196854 Metabolism of vitamins and cofactors
Reactome:R-BTA-70263 Gluconeogenesis
Reactome:R-BTA-70268 Pyruvate metabolism
Reactome:R-BTA-196854 Metabolism of vitamins and cofactors
Reactome:R-CEL-1430728 Metabolism
Reactome:R-CEL-196854 Metabolism of vitamins and cofactors
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-3323169 Defects in biotin (Btn) metabolism
Reactome:R-MMU-70263 Gluconeogenesis
Reactome:R-RNO-71387 Carbohydrate metabolism
Reactome:R-RNO-70326 Glucose metabolism
Reactome:R-SCE-196854 Metabolism of vitamins and cofactors
Reactome:R-SPO-70263 Gluconeogenesis
Reactome:R-SPO-70268 Pyruvate metabolism
Reactome:R-SPO-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-SPO-196780 Biotin transport and metabolism
WikiPathways:WP5031 Biotin metabolism, including IMDs
PathBank:SMP0120440 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency
PathBank:SMP0120444 3-Methylglutaconic Aciduria Type IV
PathBank:SMP0120516 Maple Syrup Urine Disease
PathBank:SMP0120528 Methylmalonic Aciduria Due to Cobalamin-Related Disorders
PathBank:SMP0120589 Isovaleric Acidemia
PathBank:SMP0121182 Citrate Cycle
PathBank:SMP0000055 Alanine Metabolism
PathBank:SMP0000334 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
PathBank:SMP0000374 Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
PathBank:SMP0000548 Mitochondrial Complex II Deficiency
PathBank:SMP0000560 Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1)
PathBank:SMP0002295 The Oncogenic Action of Fumarate
PathBank:SMP0002358 The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria
PathBank:SMP0063656 Propanoate Metabolism
PathBank:SMP0120439 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency
PathBank:SMP0120443 3-Methylglutaconic Aciduria Type III
PathBank:SMP0120459 beta-Ketothiolase Deficiency
PathBank:SMP0120503 Isovaleric Aciduria
PathBank:SMP0120523 Methylmalonate Semialdehyde Dehydrogenase Deficiency
PathBank:SMP0120588 Isobutyryl-CoA Dehydrogenase Deficiency
PathBank:SMP0000196 Leigh Syndrome
PathBank:SMP0000547 Fumarase Deficiency
PathBank:SMP0000551 Pyruvate Dehydrogenase Deficiency (E2)
PathBank:SMP0000559 Pyruvate Kinase Deficiency
PathBank:SMP0000563 Triosephosphate Isomerase Deficiency
PathBank:SMP0002292 The Oncogenic Action of Succinate
PathBank:SMP0087425 Alanine Metabolism
PathBank:SMP0087449 Pyruvate Metabolism
PathBank:SMP0063678 Threonine and 2-Oxobutanoate Degradation
PathBank:SMP0063689 Valine, Leucine, and Isoleucine Degradation
PathBank:SMP0120441 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I
PathBank:SMP0120525 Methylmalonic Aciduria
PathBank:SMP0120537 Propionic Acidemia
PathBank:SMP0120586 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency
PathBank:SMP0000057 Citric Acid Cycle
PathBank:SMP0000128 Gluconeogenesis
PathBank:SMP0000352 Primary Hyperoxaluria Type I
PathBank:SMP0000212 Pyruvate Dehydrogenase Complex Deficiency
PathBank:SMP0000549 2-Ketoglutarate Dehydrogenase Complex Deficiency
PathBank:SMP0000573 Glycogenosis, Type IB
PathBank:SMP0000581 Glycogenosis, Type IA. Von Gierke Disease
PathBank:SMP0000654 Warburg Effect
PathBank:SMP0002359 The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria
PathBank:SMP0087424 Citric Acid Cycle
PathBank:SMP0087492 Transfer of Acetyl Groups into Mitochondria
PathBank:SMP0120442 3-Methylglutaconic Aciduria Type I
PathBank:SMP0120514 Malonic Aciduria
PathBank:SMP0120567 Malonyl-CoA Decarboxylase Deficiency
PathBank:SMP0120587 3-Hydroxyisobutyric Aciduria
PathBank:SMP0000060 Pyruvate Metabolism
PathBank:SMP0000350 Pyruvate Carboxylase Deficiency
PathBank:SMP0000313 Lactic Acidemia
PathBank:SMP0000466 Transfer of Acetyl Groups into Mitochondria
PathBank:SMP0000546 Congenital Lactic Acidosis
PathBank:SMP0000550 Pyruvate Dehydrogenase Deficiency (E3)
PathBank:SMP0000558 Primary Hyperoxaluria II, PH2
PathBank:SMP0000562 Fructose-1,6-diphosphatase Deficiency
PathBank:SMP0000574 Glycogenosis, Type IC
PathBank:SMP0002291 The Oncogenic Action of 2-Hydroxyglutarate
PathBank:SMP0002298 Glutaminolysis and Cancer
PathBank:SMP0002355 Pyruvate Metabolism
PathBank:SMP0087527 Warburg Effect