EC: 6.2.1.3

long-chain-fatty-acid-CoA ligase (long-chain fatty acid:CoA ligase (AMP-forming))

enzyme lambda metabolic reaction experiment
uniprot:Q9M0X9 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype At4g05160]

ATP + Myristic_acid + Coenzyme_A -> Diphosphate + Myristoyl_CoA + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl, 2 mM Dithioerythritol, 10 mM MgCl2, 0.1 mM NADH, 1 mM Phosphoenolpyruvate, 12 nkatal/ml Myokinase, 7 nkatal/ml Pyruvate kinase, 9 nkatal/ml Lactate dehydrogenase, 0.1% Triton X-100
PH: 7.5
Temperature: 36
uniprot:Q84P23 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype At5g63380]

Myristic_acid + Coenzyme_A + ATP -> Myristoyl_CoA + AMP + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl, 2 mM Dithioerythritol, 10 mM MgCl2, 0.1 mM NADH, 1 mM Phosphoenolpyruvate, 12 nkatal/ml Myokinase, 7 nkatal/ml Pyruvate kinase, 9 nkatal/ml Lactate dehydrogenase, 0.1% Triton X-100
PH: 7.5
Temperature: 36
uniprot:Q84P23 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype At5g63380]

Coenzyme_A + Hexanoate + ATP -> Hexanoyl_CoA + AMP + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl, 2 mM Dithioerythritol, 10 mM MgCl2, 0.1 mM NADH, 1 mM Phosphoenolpyruvate, 12 nkatal/ml Myokinase, 7 nkatal/ml Pyruvate kinase, 9 nkatal/ml Lactate dehydrogenase
PH: 7.5
Temperature: 36
uniprot:Q84P23 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype At5g63380]

Coenzyme_A + Nonanoate + ATP -> Nonanoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl, 2 mM Dithioerythritol, 10 mM MgCl2, 0.1 mM NADH, 1 mM Phosphoenolpyruvate, 12 nkatal/ml Myokinase, 7 nkatal/ml Pyruvate kinase, 9 nkatal/ml Lactate dehydrogenase
PH: 7.5
Temperature: 36
uniprot:Q9M0X9 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype At4g05160]

ATP + Coenzyme_A + Hexanoate -> AMP + Hexanoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl, 2 mM Dithioerythritol, 10 mM MgCl2, 0.1 mM NADH, 1 mM Phosphoenolpyruvate, 12 nkatal/ml Myokinase, 7 nkatal/ml Pyruvate kinase, 9 nkatal/ml Lactate dehydrogenase
PH: 7.5
Temperature: 36
uniprot:Q9M0X9 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype At4g05160]

ATP + Coenzyme_A + Nonanoate -> AMP + Diphosphate + Nonanoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl, 2 mM Dithioerythritol, 10 mM MgCl2, 0.1 mM NADH, 1 mM Phosphoenolpyruvate, 12 nkatal/ml Myokinase, 7 nkatal/ml Pyruvate kinase, 9 nkatal/ml Lactate dehydrogenase
PH: 7.5
Temperature: 36
- [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype]

Coenzyme_A + Oleate + ATP -> AMP + Oleoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) mutant T214A]

Oleate + ATP + Coenzyme_A -> AMP + Diphosphate + Oleoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) mutant T217A]

Coenzyme_A + Oleate + ATP -> AMP + Oleoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) mutant G216A]

Oleate + Coenzyme_A + ATP -> AMP + Oleoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) mutant G219A]

ATP + Coenzyme_A + Oleate -> Diphosphate + Oleoyl_CoA + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) mutant K222A]

Oleate + Coenzyme_A + ATP -> Oleoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) mutant T213A]

ATP + Oleate + Coenzyme_A -> AMP + Diphosphate + Oleoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) mutant E361A]

Oleate + ATP + Coenzyme_A -> AMP + Oleoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) mutant E361A]

Oleate -> Oleate		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype]

Oleate -> Oleate		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) mutant T217A]

Oleate -> Oleate		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
- [long-chain-fatty-acid---CoA ligase(Enzyme) mutant Y213A]

Oleate -> Oleate		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM Tris-HCl, 8 mM MgCl2, 2 mM EDTA, 20 mM NaF, 0.1 % Trion X-100
PH: 7.5
Temperature: 37
uniprot:Q9ULC5 [Magnesium chloride]

Palmitate + Coenzyme_A + ATP -> AMP + Palmitoyl_CoA + Diphosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 2.0 mM EDTA, 2.0 mM DTT, 0.2% triton X-100
PH: 9.5
Temperature: 30
uniprot:Q9ULC5 [Magnesium chloride]

Palmitate + Coenzyme_A + ATP -> Palmitoyl_CoA + Diphosphate + AMP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 2.0 mM EDTA, 2.0 mM DTT, 0.2% triton X-100
PH: 7.5
Temperature: 30
uniprot:Q9ULC5 [Magnesium chloride]

Coenzyme_A + ATP + Palmitate -> Palmitoyl_CoA + Diphosphate + AMP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 2.0 mM EDTA, 2.0 mM DTT, 0.2% triton X-100
PH: 8.5
Temperature: 30
uniprot:Q9ULC5 [Magnesium chloride]

ATP + Palmitate + Coenzyme_A -> AMP + Diphosphate + Palmitoyl_CoA		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 2.0 mM EDTA, 2.0 mM DTT, 0.2% triton X-100
PH: 7.5
Temperature: 30
- [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype]

Palmitate + ATP + Coenzyme_A -> AMP + Diphosphate + Palmitoyl_CoA		 (( (Vmax * B) ) / (Km + B)) buffer: 150 mM Tris-HCl, 5 mM MgCl2, 5 mM DTT
PH: 7.4
Temperature: 36
- [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype]

ATP + Coenzyme_A + Palmitate -> Diphosphate + Palmitoyl_CoA + AMP		 (( (Vmax * B) ) / (Km + B)) buffer: 150 mM Tris-HCl, 5 mM MgCl2, 5 mM DTT
PH: 7.4
Temperature: 36
- [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype]

Coenzyme_A + ATP + Palmitate -> AMP + Palmitoyl_CoA + Diphosphate		 (( (Vmax * C) ) / (Km + C)) buffer: 150 mM Tris-HCl, 5 mM MgCl2, 5 mM DTT
PH: 7.4
Temperature: 36
- [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype]

Palmitate + ATP + Coenzyme_A -> AMP + Diphosphate + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 150 mM Tris-HCl, 5 mM MgCl2, 5 mM DTT
PH: 7.4
Temperature: 36
- [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype]

ATP + Palmitate + Coenzyme_A -> Diphosphate + AMP + Palmitoyl_CoA		 (( (Vmax * C) ) / (Km + C)) buffer: 150 mM Tris-HCl, 5 mM MgCl2, 5 mM DTT
PH: 7.4
Temperature: 36
- [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype]

Coenzyme_A + ATP + Palmitate -> AMP + Diphosphate + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 150 mM Tris-HCl, 5 mM MgCl2, 5 mM DTT
PH: 7.4
Temperature: 36
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-4.6]

ATP + Palmitate + Coenzyme_A -> AMP + Diphosphate + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-4.6]

Palmitate + ATP + Coenzyme_A -> Palmitoyl_CoA + Diphosphate + AMP		 (( (Vmax * C) ) / (Km + C)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-4.6]

Dodecanoate + Coenzyme_A + ATP -> AMP + Diphosphate + Lauroyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-4.6]

Coenzyme_A + ATP + Myristic_acid -> AMP + Myristoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-4.6]

Coenzyme_A + Decanoate + ATP -> Decanoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-4.6]

Coenzyme_A + Stearate + ATP -> Stearoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-4.6]

Coenzyme_A + Octanoate + ATP -> AMP + Diphosphate + Octanoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.0]

Coenzyme_A + ATP + Palmitate -> Palmitoyl_CoA + Diphosphate + AMP		 (( (Vmax * B) ) / (Km + B)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-4.6]

Coenzyme_A + ATP + Palmitate -> Palmitoyl_CoA + Diphosphate + AMP		 (( (Vmax * B) ) / (Km + B)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.0]

Palmitate + ATP + Coenzyme_A -> AMP + Diphosphate + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.0]

Coenzyme_A + Palmitate + ATP -> Diphosphate + AMP + Palmitoyl_CoA		 (( (Vmax * C) ) / (Km + C)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.0]

Coenzyme_A + Dodecanoate + ATP -> Lauroyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.0]

Coenzyme_A + Myristic_acid + ATP -> AMP + Diphosphate + Myristoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.0]

ATP + Coenzyme_A + Octanoate -> Octanoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.0]

Coenzyme_A + ATP + Decanoate -> AMP + Diphosphate + Decanoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.0]

Coenzyme_A + ATP + Stearate -> Diphosphate + AMP + Stearoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.6]

Palmitate + ATP + Coenzyme_A -> Diphosphate + Palmitoyl_CoA + AMP		 (( (Vmax * C) ) / (Km + C)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.6]

Palmitate + ATP + Coenzyme_A -> AMP + Palmitoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.6]

ATP + Coenzyme_A + Palmitate -> AMP + Diphosphate + Palmitoyl_CoA		 (( (Vmax * B) ) / (Km + B)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.6]

Dodecanoate + ATP + Coenzyme_A -> Diphosphate + Lauroyl_CoA + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.6]

Coenzyme_A + Myristic_acid + ATP -> Diphosphate + AMP + Myristoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.6]

Coenzyme_A + ATP + Decanoate -> AMP + Diphosphate + Decanoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.6]

Stearate + ATP + Coenzyme_A -> Diphosphate + Stearoyl_CoA + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:P69451 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype Acyl-CoA synthetase-5.6]

ATP + Coenzyme_A + Octanoate -> Diphosphate + AMP + Octanoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 200 mM potassium phosphate, 5 mM MgCl2, 0.1 % Triton X-100, 0.2 mM NADH, 0.3 mM phosphoenolpyruvate, 8 µg/ml myokinase, 20 µg/ml pyruvate kinase, 28.8 µg/ml lactate dehydrogenase
PH: 7.5
Temperature: 37
uniprot:O88813 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype isoform ACS5]

Palmitate + ATP + Coenzyme_A -> Palmitoyl_CoA + AMP + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 175 mM Tris, 1 µM EDTA, 8 mM MgCl2, 5 mM Dithiothreitol, 0.5 mM Triton X-100
PH: 7.5
Temperature: 37
uniprot:O35547 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype isoform ACS4]

Coenzyme_A + ATP + Palmitate -> Diphosphate + AMP + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 175 mM Tris, 1 µM EDTA, 8 mM MgCl2, 5 mM Dithiothreitol, 0.5 mM Triton X-100
PH: 7.5
Temperature: 37
uniprot:P18163 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype isoform ACS1]

ATP + Palmitate + Coenzyme_A -> AMP + Diphosphate + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 175 mM Tris, 1 µM EDTA, 8 mM MgCl2, 5 mM Dithiothreitol, 0.5 mM Triton X-100
PH: 7.5
Temperature: 37
uniprot:O88813 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype isoform ACS5]

ATP + Palmitate + Coenzyme_A -> Palmitoyl_CoA + AMP + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 175 mM Tris, 1 µM EDTA, 8 mM MgCl2, 5 mM Dithiothreitol, 0.5 mM Triton X-100
PH: 7.5
Temperature: 37
uniprot:O88813 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype isoform ACS5]

Palmitate + Coenzyme_A + ATP -> Palmitoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 175 mM Tris, 1 µM EDTA, 8 mM MgCl2, 5 mM Dithiothreitol, 0.5 mM Triton X-100
PH: 7.5
Temperature: 37
uniprot:P18163 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype isoform ACS1]

Palmitate + ATP + Coenzyme_A -> Diphosphate + AMP + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 175 mM Tris, 1 µM EDTA, 8 mM MgCl2, 5 mM Dithiothreitol, 0.5 mM Triton X-100
PH: 7.5
Temperature: 37
uniprot:P18163 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype isoform ACS1]

ATP + Coenzyme_A + Palmitate -> Palmitoyl_CoA + AMP + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 175 mM Tris, 1 µM EDTA, 8 mM MgCl2, 5 mM Dithiothreitol, 0.5 mM Triton X-100
PH: 7.5
Temperature: 37
uniprot:O35547 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype isoform ACS4]

ATP + Palmitate + Coenzyme_A -> Palmitoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 175 mM Tris, 1 µM EDTA, 8 mM MgCl2, 5 mM Dithiothreitol, 0.5 mM Triton X-100
PH: 7.5
Temperature: 37
uniprot:O35547 [long-chain-fatty-acid---CoA ligase(Enzyme) wildtype isoform ACS4]

Palmitate + ATP + Coenzyme_A -> AMP + Palmitoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 175 mM Tris, 1 µM EDTA, 8 mM MgCl2, 5 mM Dithiothreitol, 0.5 mM Triton X-100
PH: 7.5
Temperature: 37
uniprot:O35547 [Troglitazone]

Coenzyme_A + Palmitate + ATP -> AMP + Palmitoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + (A * (1 + (I / Ki))))) buffer: 175 mM Tris, 1 µM EDTA, 8 mM MgCl2, 5 mM Dithiothreitol, 0.5 mM Triton X-100, 2.5 % DMSO
PH: 7.5
Temperature: 37
uniprot:O35547 [Mg2+]

Palmitate + ATP + Coenzyme_A -> Diphosphate + AMP + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P18163 [Mg2+]

Coenzyme_A + Palmitate + ATP -> Diphosphate + AMP + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P18163 [Mg2+]

ATP + Coenzyme_A + Oleate -> Oleoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P18163 [Mg2+]

ATP + Coenzyme_A + Stearate -> Diphosphate + Stearoyl_CoA + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O35547 [Mg2+]

Coenzyme_A + Stearate + ATP -> Diphosphate + Stearoyl_CoA + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P33124 [Mg2+]

Linoleate + ATP + Coenzyme_A -> AMP + Linoleoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P33124 [Mg2+]

Coenzyme_A + Arachidonate + ATP -> Arachidonyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P18163 [Mg2+]

Coenzyme_A + ATP + Linoleate -> AMP + Diphosphate + Linoleoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P18163 [Mg2+]

Coenzyme_A + ATP + Arachidonate -> AMP + Diphosphate + Arachidonyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P18163 [Mg2+]

Palmitate + Coenzyme_A + ATP -> Diphosphate + Palmitoyl_CoA + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P18163 [Mg2+]

Oleate + Coenzyme_A + ATP -> Oleoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P18163 [Mg2+]

Coenzyme_A + ATP + Stearate -> Diphosphate + AMP + Stearoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P18163 [Mg2+]

Coenzyme_A + ATP + Arachidonate -> Diphosphate + AMP + Arachidonyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P18163 [Mg2+]

Linoleate + ATP + Coenzyme_A -> AMP + Diphosphate + Linoleoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O35547 [Mg2+]

Oleate + ATP + Coenzyme_A -> AMP + Diphosphate + Oleoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O35547 [Mg2+]

Arachidonate + Coenzyme_A + ATP -> AMP + Arachidonyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O35547 [Mg2+]

ATP + Coenzyme_A + Linoleate -> Diphosphate + AMP + Linoleoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O88813 [Mg2+]

ATP + Coenzyme_A + Palmitate -> Diphosphate + Palmitoyl_CoA + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P33124 [Mg2+]

Palmitate + Coenzyme_A + ATP -> Diphosphate + AMP + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P33124 [Mg2+]

Coenzyme_A + Oleate + ATP -> Oleoyl_CoA + AMP + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O88813 [Mg2+]

ATP + Oleate + Coenzyme_A -> Diphosphate + AMP + Oleoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:P33124 [Mg2+]

Stearate + Coenzyme_A + ATP -> AMP + Stearoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O88813 [Mg2+]

Stearate + Coenzyme_A + ATP -> Diphosphate + AMP + Stearoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O35547 [Mg2+]

Coenzyme_A + Arachidonate + ATP -> Arachidonyl_CoA + AMP + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O88813 [Mg2+]

ATP + Arachidonate + Coenzyme_A -> Arachidonyl_CoA + AMP + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O88813 [Mg2+]

ATP + Linoleate + Coenzyme_A -> AMP + Linoleoyl_CoA + Diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:Q63151 [Mg2+]

ATP + Coenzyme_A + Palmitate -> Palmitoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O35547 [Mg2+]

Coenzyme_A + Palmitate + ATP -> Diphosphate + AMP + Palmitoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:Q63151 [Mg2+]

Oleate + ATP + Coenzyme_A -> AMP + Diphosphate + Oleoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O35547 [Mg2+]

Oleate + Coenzyme_A + ATP -> Oleoyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:Q63151 [Mg2+]

ATP + Stearate + Coenzyme_A -> Diphosphate + AMP + Stearoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O35547 [Mg2+]

Stearate + Coenzyme_A + ATP -> AMP + Diphosphate + Stearoyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:Q63151 [Mg2+]

Linoleate + Coenzyme_A + ATP -> Diphosphate + Linoleoyl_CoA + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:Q63151 [Mg2+]

Coenzyme_A + ATP + Arachidonate -> Arachidonyl_CoA + Diphosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37
uniprot:O35547 [Mg2+]

Coenzyme_A + ATP + Linoleate -> Diphosphate + Linoleoyl_CoA + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl, 5 mM dithiothreitol, 150 mM KCl, 1.0 mM potassium phosphoenolpyruvate, 0.3 mM NADH, 45 µg/ml adenylate kinase, 30 µg/ml pyruvate kinase, 30 µg/ml lactate dehydrogenase
PH: 8
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_PWY-7592 arachidonate biosynthesis III (metazoa)
BioCyc:META_PWY-7592 arachidonate biosynthesis III (6-desaturase, mammals)
BioCyc:META_PWY-1121 suberin monomers biosynthesis
BioCyc:META_FAO-PWY fatty acid β-oxidation I
BioCyc:ECO_FAO-PWY fatty acid β-oxidation I
BioCyc:YEAST_PWY-7288 fatty acid β-oxidation (peroxisome)
BioCyc:ARA_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:MTBH37RV_PWY-6946 cholesterol degradation to androstenedione II (cholesterol dehydrogenase)
BioCyc:MTBCDC1551_PWY-5970 fatty acids biosynthesis (yeast)
BioCyc:MOUSE_PWY-5143 fatty acid activation
BioCyc:BSUB_PWY-5143 long-chain fatty acid activation
BioCyc:BSUB_FAO-PWY fatty acid β-oxidation I
BioCyc:ECOL316407_FAO-PWY fatty acid β-oxidation I
BioCyc:HUMAN_PWY-5143 fatty acid activation
BioCyc:HUMAN_PWY66-387 fatty acid α-oxidation
BioCyc:META_PWY3DJ-11470 sphingosine and sphingosine-1-phosphate metabolism
BioCyc:META_PWY-5143 long-chain fatty acid activation
BioCyc:META_PWY66-387 fatty acid α-oxidation II
BioCyc:META_PWY-6946 cholesterol degradation to androstenedione II (cholesterol dehydrogenase)
BioCyc:ARA_PHOSLIPSYN2-PWY superpathway of phospholipid biosynthesis II (plants)
BioCyc:ARA_PWY-6803 phosphatidylcholine acyl editing
BioCyc:MTBH37RV_FAO-PWY fatty acid β-oxidation I
BioCyc:MOUSE_PWY-5535 acetate formation from acetyl-CoA II
BioCyc:HUMAN_PWY-7049 icosapentaenoate biosynthesis II (metazoa)
BioCyc:HUMAN_PWY-6000 γ-linolenate biosynthesis
BioCyc:META_PWY-321 cutin biosynthesis
BioCyc:META_PWY-7288 fatty acid β-oxidation (peroxisome, yeast)
BioCyc:YEAST_PWY-5143 fatty acid activation
BioCyc:ARA_PWY-5143 long-chain fatty acid activation
BioCyc:ARA_PWY-5136 fatty acid β-oxidation II (peroxisome)
BioCyc:ARA_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis
BioCyc:ARA_PWY-7625 phosphatidylinositol biosynthesis II (eukaryotes)
BioCyc:MTBH37RV_PWY-6947 superpathway of cholesterol degradation II (cholesterol dehydrogenase)
BioCyc:MTBH37RV_PWY-6945 cholesterol degradation to androstenedione I (cholesterol oxidase)
BioCyc:ECOO157_FAO-PWY fatty acid β-oxidation I
BioCyc:HUMAN_PWY-5972 stearate biosynthesis
BioCyc:HUMAN_FAO-PWY fatty acid β-oxidation
BioCyc:HUMAN_PWY66-391 fatty acid β-oxidation (peroxisome)
BioCyc:META_PWY-561 superpathway of glyoxylate cycle and fatty acid degradation
BioCyc:META_PWY-6920 6-gingerol analog biosynthesis (engineered)
BioCyc:META_PWY-6000 γ-linolenate biosynthesis II (animals)
BioCyc:META_PWY-5136 fatty acid β-oxidation II (peroxisome)
BioCyc:META_PWY66-391 fatty acid β-oxidation VI (peroxisome)
BioCyc:META_PWY-7724 icosapentaenoate biosynthesis III (8-desaturase, mammals)
BioCyc:META_PWY-7049 icosapentaenoate biosynthesis II (6-desaturase, mammals)
BioCyc:META_PWY-6947 superpathway of cholesterol degradation II (cholesterol dehydrogenase)
BioCyc:META_PWY-6945 cholesterol degradation to androstenedione I (cholesterol oxidase)
BioCyc:META_PWY-5972 stearate biosynthesis I (animals and fungi)
BioCyc:YEAST_YEAST-FAO-PWY fatty acid oxidation (non-cyclic)
BioCyc:MOUSE_FAO-PWY fatty acid β-oxidation I
BioCyc:MOUSE_PWY-6000 γ-linolenate biosynthesis II (animals)
BioCyc:MOUSE_PWY-5136 fatty acid β-oxidation II (core pathway)
PathBank:SMP0000781 Fatty Acid Oxidation
PlantCyc:PLANT_PWY-5136 fatty acid β-oxidation II (peroxisome)
PlantCyc:ARA_PWY-561 superpathway of glyoxylate cycle and fatty acid degradation
PlantCyc:ARA_PWY-5143 long-chain fatty acid activation
PlantCyc:ARA_PHOSLIPSYN2-PWY superpathway of phospholipid biosynthesis II (plants)
PlantCyc:ARA_PWY-6803 phosphatidylcholine acyl editing
PlantCyc:ARA_PWY-5136 fatty acid β-oxidation II (peroxisome)
PlantCyc:PLANT_PWY-5143 long-chain fatty acid activation
PlantCyc:PLANT_PWY-561 superpathway of glyoxylate cycle and fatty acid degradation
Reactome:R-HSA-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
Reactome:R-HSA-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes
Reactome:R-HSA-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes
Reactome:R-HSA-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Reactome:R-DDI-2046104 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Reactome:R-HSA-400206 Regulation of lipid metabolism by PPARalpha
Reactome:R-HSA-75105 Fatty acyl-CoA biosynthesis
Reactome:R-HSA-2046106 alpha-linolenic acid (ALA) metabolism
Reactome:R-HSA-194068 Bile acid and bile salt metabolism
Reactome:R-HSA-74160 Gene expression (Transcription)
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-MMU-75105 Fatty acyl-CoA biosynthesis
Reactome:R-MMU-2046106 alpha-linolenic acid (ALA) metabolism
Reactome:R-MMU-8957322 Metabolism of steroids
Reactome:R-MMU-193775 Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Reactome:R-RNO-8978868 Fatty acid metabolism
Reactome:R-RNO-2046104 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Reactome:R-RNO-389599 Alpha-oxidation of phytanate
Reactome:R-RNO-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Reactome:R-SCE-2046106 alpha-linolenic acid (ALA) metabolism
Reactome:R-DDI-8978868 Fatty acid metabolism
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-8978868 Fatty acid metabolism
Reactome:R-HSA-2046104 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Reactome:R-HSA-389599 Alpha-oxidation of phytanate
Reactome:R-HSA-193775 Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Reactome:R-HSA-212165 Epigenetic regulation of gene expression
Reactome:R-MMU-8978868 Fatty acid metabolism
Reactome:R-MMU-2046104 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Reactome:R-MMU-389599 Alpha-oxidation of phytanate
Reactome:R-MMU-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Reactome:R-RNO-390918 Peroxisomal lipid metabolism
Reactome:R-RNO-192105 Synthesis of bile acids and bile salts
Reactome:R-RNO-159418 Recycling of bile acids and salts
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-8978868 Fatty acid metabolism
Reactome:R-SCE-2046104 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Reactome:R-DDI-2046106 alpha-linolenic acid (ALA) metabolism
Reactome:R-HSA-1989781 PPARA activates gene expression
Reactome:R-HSA-75876 Synthesis of very long-chain fatty acyl-CoAs
Reactome:R-HSA-2046105 Linoleic acid (LA) metabolism
Reactome:R-HSA-390247 Beta-oxidation of very long chain fatty acids
Reactome:R-HSA-192105 Synthesis of bile acids and bile salts
Reactome:R-HSA-159418 Recycling of bile acids and salts
Reactome:R-MMU-2046105 Linoleic acid (LA) metabolism
Reactome:R-MMU-390247 Beta-oxidation of very long chain fatty acids
Reactome:R-MMU-194068 Bile acid and bile salt metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-556833 Metabolism of lipids
Reactome:R-RNO-75105 Fatty acyl-CoA biosynthesis
Reactome:R-RNO-2046106 alpha-linolenic acid (ALA) metabolism
Reactome:R-RNO-8957322 Metabolism of steroids
Reactome:R-RNO-193775 Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Reactome:R-SCE-556833 Metabolism of lipids
Reactome:R-SCE-2046105 Linoleic acid (LA) metabolism
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DDI-556833 Metabolism of lipids
Reactome:R-DDI-2046105 Linoleic acid (LA) metabolism
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-2142753 Arachidonate metabolism
Reactome:R-HSA-390918 Peroxisomal lipid metabolism
Reactome:R-HSA-8957322 Metabolism of steroids
Reactome:R-HSA-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Reactome:R-MMU-390918 Peroxisomal lipid metabolism
Reactome:R-MMU-192105 Synthesis of bile acids and bile salts
Reactome:R-MMU-159418 Recycling of bile acids and salts
Reactome:R-RNO-2046105 Linoleic acid (LA) metabolism
Reactome:R-RNO-390247 Beta-oxidation of very long chain fatty acids
Reactome:R-RNO-194068 Bile acid and bile salt metabolism
WikiPathways:WP5176 Disorders of bile acid synthesis and biliary transport
WikiPathways:WP5181 Roles of ceramides in development of insulin resistance
PathBank:SMP0120822 Carnitine Palmitoyl Transferase Deficiency I
PathBank:SMP0120826 Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD)
PathBank:SMP0120468 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0120476 Ethylmalonic Encephalopathy
PathBank:SMP0120520 Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency)
PathBank:SMP0120581 Adrenoleukodystrophy, X-Linked
PathBank:SMP0120605 Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD)
PathBank:SMP0120609 Trifunctional Protein Deficiency
PathBank:SMP0000051 Fatty Acid Metabolism
PathBank:SMP0000235 Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency)
PathBank:SMP0000052 Beta Oxidation of Very Long Chain Fatty Acids
PathBank:SMP0000482 Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
PathBank:SMP0000318 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0000516 Adrenoleukodystrophy, X-Linked
PathBank:SMP0000540 Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD)
PathBank:SMP0002324 Biosynthesis of Unsaturated Fatty Acids
PathBank:SMP0002346 Biosynthesis of Unsaturated Fatty Acids (Icosanoyl-CoA)
PathBank:SMP0087217 Phytanic Acid Peroxisomal Oxidation
PathBank:SMP0120697 Familial Hypercholanemia (FHCA)
PathBank:SMP0120749 Refsum Disease
PathBank:SMP0120801 Carnitine-Acylcarnitine Translocase Deficiency
PathBank:SMP0120825 Carnitine Palmitoyl Transferase Deficiency II
PathBank:SMP0120463 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0120467 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0120495 Zellweger Syndrome
PathBank:SMP0120604 Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
PathBank:SMP0000035 Bile Acid Biosynthesis
PathBank:SMP0000185 Glutaric Aciduria Type I
PathBank:SMP0000314 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0000315 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0000539 Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
PathBank:SMP0002329 Biosynthesis of Unsaturated Fatty Acids (Docosanoyl-CoA)
PathBank:SMP0002361 Fatty Acid Metabolism
PathBank:SMP0087329 Bile Acid Biosynthesis
PathBank:SMP0120652 27-Hydroxylase Deficiency
PathBank:SMP0120688 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0120696 Ethylmalonic Encephalopathy
PathBank:SMP0120740 Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency)
PathBank:SMP0120800 Adrenoleukodystrophy, X-Linked
PathBank:SMP0120824 Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD)
PathBank:SMP0120828 Trifunctional Protein Deficiency
PathBank:SMP0120477 Familial Hypercholanemia (FHCA)
PathBank:SMP0120582 Carnitine-Acylcarnitine Translocase Deficiency
PathBank:SMP0120606 Carnitine Palmitoyl Transferase Deficiency II
PathBank:SMP0000030 Oxidation of Branched-Chain Fatty Acids
PathBank:SMP0000450 Phytanic Acid Peroxisomal Oxidation
PathBank:SMP0000317 Familial Hypercholanemia (FHCA)
PathBank:SMP0000517 Carnitine-Acylcarnitine Translocase Deficiency
PathBank:SMP0000541 Carnitine Palmitoyl Transferase Deficiency II
PathBank:SMP0000545 Trifunctional Protein Deficiency
PathBank:SMP0002325 Biosynthesis of Unsaturated Fatty Acids (Tetracosanoyl-CoA)
PathBank:SMP0002347 Biosynthesis of Unsaturated Fatty Acids (Stearoyl-CoA)
PathBank:SMP0086926 Oxidation of Branched-Chain Fatty Acids
PathBank:SMP0087236 Bile Acid Biosynthesis
PathBank:SMP0087280 Fatty Acid Metabolism
PathBank:SMP0087312 Phytanic Acid Peroxisomal Oxidation
PathBank:SMP0087348 Oxidation of Branched-Chain Fatty Acids
PathBank:SMP0087352 Beta Oxidation of Very Long Chain Fatty Acids
PathBank:SMP0087360 Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
PathBank:SMP0012062 Fatty Acid Beta-Oxidation I
PathBank:SMP0063598 Beta Oxidation of Very Long Chain Fatty Acids
PathBank:SMP0120683 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0120687 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0120715 Zellweger Syndrome
PathBank:SMP0120823 Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
PathBank:SMP0120871 27-Hydroxylase Deficiency
PathBank:SMP0120603 Carnitine Palmitoyl Transferase Deficiency I
PathBank:SMP0120607 Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD)
PathBank:SMP0000181 Ethylmalonic Encephalopathy
PathBank:SMP0000451 Refsum Disease
PathBank:SMP0000316 Zellweger Syndrome
PathBank:SMP0000538 Carnitine Palmitoyl Transferase Deficiency I
PathBank:SMP0000542 Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD)
PathBank:SMP0000720 27-Hydroxylase Deficiency
PathBank:SMP0063589 Fatty Acid Metabolism
PathBank:SMP0063601 Bile Acid Biosynthesis
PathBank:SMP0063639 Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids