NPY1 - Saccharomyces cerevisiae S288C
NAD-capped RNA hydrolase NPY1
> NPY1 - Saccharomyces cerevisiae S288C [NAD-capped RNA hydrolase NPY1]
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Metadata
Organism Source: 559292 - Saccharomyces cerevisiae S288C
EC Number: 3.6.1.- / 3.6.1.22
Cluster:
Registry Model:
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R00056 | dinucleotide nucleotidohydrolase | general reaction |
| KEGG:R00086 | ATP phosphohydrolase | ATP + H2O <=> ADP + Orthophosphate |
| KEGG:R00103 | NAD+ phosphohydrolase | NAD+ + H2O <=> AMP + Nicotinamide D-ribonucleotide |
| KEGG:R00515 | CTP diphosphohydrolase (diphosphate-forming); | CTP + H2O <=> CMP + Diphosphate |
| KEGG:R00615 | thiamin diphosphate phosphohydrolase | Thiamin diphosphate + H2O <=> Thiamin monophosphate + Orthophosphate |
| KEGG:R00662 | uridine triphosphate pyrophosphohydrolase | UTP + H2O <=> UMP + Diphosphate |
| KEGG:R00881 | GDP-mannose mannophosphohydrolase | GDP-mannose + H2O <=> GMP + D-Mannose 1-phosphate |
| KEGG:R01054 | ADP-ribose ribophosphohydrolase | ADP-ribose + H2O <=> AMP + D-Ribose 5-phosphate |
| KEGG:R01233 | GDPglucose sugarphosphohydrolase | GDP-glucose + H2O <=> GMP + D-Glucose 1-phosphate |
| KEGG:R01855 | 2'-deoxyguanosine 5'-triphosphate diphosphohydrolase | dGTP + H2O <=> dGMP + Diphosphate |
| KEGG:R03004 | deamino-NAD+ nucleotidohydrolase | Deamino-NAD+ + H2O <=> AMP + Nicotinate D-ribonucleotide |
| KEGG:R04621 | C04874 + C00009<=>C05925 + C00001 | 7,8-Dihydroneopterin + Orthophosphate <=> Dihydroneopterin phosphate + H2O |
| KEGG:R10814 | 5'-triphospho-[mRNA] phosphohydrolase | mRNA 5'-triphosphatase |
| KEGG:R10816 | 5'-triphospho-[mRNA] diphosphatase | RNA pyrophosphohydrolase |
| KEGG:R11104 | NADH phosphohydrolase | NADH + H2O <=> AMP + NMNH |
| KEGG:R11323 | dTTP diphosphohydrolase | dTTP + H2O <=> dTMP + Diphosphate |
| KEGG:R12499 | C22217 + C00001<=>C06452 + C00055 | HPP-CMP hydrolase |
| KEGG:R12559 | C22248 + C00001<=>C22249 + C00015 | UDP-2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-alpha-D-mannopyranose hydrolase |
| KEGG:R12564 | C22253 + C00001<=>C22254 + C00015 | UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-gulose hydrolase |
| KEGG:R12896 | prenyl diphosphate diphosphate phosphohydrolase | DMAPP dephosphorylation |
| BioCyc:RXN0-5462 | GTP + WATER --> PROTON + GDP + Pi | |
| BioCyc:RXN-11397 | CPD-12366 + WATER --> PROTON + CPD-12367 + PPI | |
| BioCyc:RXN0-384 | DATP + WATER --> PROTON + DAMP + PPI | |
| BioCyc:RXN0-385 | DGTP + WATER --> PROTON + DGMP + PPI | |
| BioCyc:RXN0-5510 | mRNAs-with-5-triphosphate + WATER --> mRNAs-with-5-monophosphate + PPI + PROTON | |
| BioCyc:RXN0-5108 | GDP-MANNOSE + WATER --> 2 PROTON + GMP + MANNOSE-1P | |
| BioCyc:RXN0-7297 | PHOSPHO-NARL + WATER --> NARL-MONOMER + Pi + PROTON | |
| BioCyc:RXN0-3542 | THIAMINE-PYROPHOSPHATE + WATER<=>PROTON + THIAMINE-P + Pi | |
| BioCyc:RXN-14188 | 5-HYDROXY-CTP + WATER --> CPD-15158 + PPI + PROTON | |
| BioCyc:RXN0-7299 | CPLX0-7748 + WATER --> CPXR-MONOMER + Pi + PROTON | |
| BioCyc:NADPYROPHOSPHAT-RXN | WATER + NAD --> 2 PROTON + NICOTINAMIDE_NUCLEOTIDE + AMP | This reaction initiates pyridine ring cycling in the PNC VIpathway by the enzymatic degradation of NAD. |
| BioCyc:RXN0-3543 | AMINO-HYDROXYMETHYL-METHYLPYRIMIDINE-PP + WATER --> PROTON + AMINO-HYDROXYMETHYL-METHYL-PYR-P + Pi | |
| BioCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN | DIHYDRONEOPTERIN-P + WATER --> DIHYDRO-NEO-PTERIN + Pi | This is a reaction in the biosynthesis of folic acid. It isuncertain whether there is a specific enzyme for this reaction. E.coli does contain nonspecific phophatases that can catalyze thisreaction. |
| BioCyc:RXN0-4401 | NADH + WATER --> 2 PROTON + NMNH + AMP | |
| BioCyc:RXN0-7283 | mRNAs-with-5-diphosphate + WATER --> mRNAs-with-5-monophosphate + Pi + PROTON | |
| Rhea:RHEA:11801 | NAD+ + H2O => β-nicotinamide D-ribonucleotide + AMP + 2 H+ | |
| Rhea:RHEA:11802 | β-nicotinamide D-ribonucleotide + AMP + 2 H+ => NAD+ + H2O | |
| Rhea:RHEA:11803 | NAD+ + H2O <=> β-nicotinamide D-ribonucleotide + AMP + 2 H+ | |
| Rhea:RHEA:48869 | NADH + H2O => reduced β-nicotinamide D-ribonucleotide + AMP + 2 H+ | |
| Rhea:RHEA:48870 | reduced β-nicotinamide D-ribonucleotide + AMP + 2 H+ => NADH + H2O | |
| Rhea:RHEA:48871 | NADH + H2O <=> reduced β-nicotinamide D-ribonucleotide + AMP + 2 H+ | |
| BioCyc:RXN-14213 | TDP + WATER<=>TMP + Pi + PROTON | |
| BioCyc:RXN-11027 | CPD-11984 + WATER --> CPD-11994 + Pi + PROTON | |
| BioCyc:RXN-14005 | 8-oxo-dADP + WATER --> CPD-15018 + Pi + PROTON | The human enzyme also hydrolyses 2-hydroxy-dADP, but at a slower rate. In contrast to |FRAME: EC-3.6.1.58 "EC 3.6.1.58, 8-oxo-dGDP phosphatase"|, this enzyme does not have any activity towards sugar-phosphates. |
| BioCyc:RXN-18071 | CPD-19362 + WATER --> CPD-19364 + UDP + PROTON | |
| BioCyc:RXN-12358 | CPD-13344 + WATER --> DIHYDRO-NEO-PTERIN + Pi | |
| BioCyc:RXN-19877 | CPD-21482 + WATER --> CPD-9465 + CMP + PROTON | |
| BioCyc:RXN-15081 | CPD-15968 + WATER --> CPD-15961 + CMP + PROTON | |
| BioCyc:RXN-17079 | CPD-18458 + WATER --> CPD-18456 + UDP + PROTON | |
| BioCyc:RXN-10811 | CO-A + WATER --> 3-5-ADP + PANTETHEINE-P + 2 PROTON | |
| BioCyc:RXN0-2604 | DNA-with-Holiday-Junctions --> DNA-Segment-Placeholder |
Pathways
| pathway id | name |
|---|---|
| BioCyc:YEAST_PERIPLASMA-NAD-DEGRADATION | periplasmic NAD degradation |
| Reactome:R-SCE-196807 | Nicotinate metabolism |
| Reactome:R-SCE-1430728 | Metabolism |
| Reactome:R-SCE-196849 | Metabolism of water-soluble vitamins and cofactors |
| Reactome:R-SCE-196854 | Metabolism of vitamins and cofactors |