Microbial Natural Product

Microbial natural products, primarily secondary metabolites produced by bacteria, fungi, and other microorganisms, remain a cornerstone of modern medicine and biotechnology. They form the foundation of numerous antibiotics (e.g., penicillin, streptomycin), anticancer agents, and immunosuppressants, addressing critical global health challenges like infectious diseases and cancer. Despite historical challenges such as compound rediscovery and complex biosynthesis, advances in genomics, metabolomics, and synthetic biology are unlocking novel chemical diversity from underexplored microbial sources. Consequently, microbial natural products continue to represent an unparalleled reservoir for discovering next-generation therapeutics, underscoring their enduring significance in drug development and sustainable bioprospecting. (98 words)


Methyl p-coumarate

Formula: C10H10O3 (178.063)

Methyl p-coumarate, also known as 4-coumaric acid methyl ester, is a member of the class of compounds known as coumaric acid esters. Coumaric acid est...

Fumiquinazoline D

Formula: C24H21N5O4 (443.1593)

Fumiquinazoline D is a member of quinazolines. NCGC00169614-02_C24H21N5O4_(1S,3S,12S,14R,27S)-12-Hydroxy-1,3-dimethyl-2,5,15,23,25-pentaazaheptacyclo...

alpha-Onocerin

Formula: C30H50O2 (442.3811)

Alpha-onocerin is a triterpenoid that is ethane in which each carbon has been substituted by a (1R,4aR,6S,8aS)-6-hydroxy-5,5,8a-trimethyl-2-methylened...

Multiflorine

Formula: C15H22N2O (246.1732)

Multiflorine is a natural product found in Lupinus pubescens, Lupinus arcticus, and other organisms with data available.

Rutin

Formula: C27H30O16 (610.1534)

Rutin is a flavonoid known to have a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogen...

Kaempferol

Formula: C15H10O6 (286.0477)

Kaempferol, also known as rhamnolutein or c.i. 75640, belongs to the class of organic compounds known as flavonols. Flavonols are compounds that conta...

Quercetin

Formula: C15H10O7 (302.0427)

Quercetin is a flavonoid widely distributed in many plants and fruits including red grapes, citrus fruit, tomato, broccoli and other leafy green veget...

Prunasin

Formula: C14H17NO6 (295.1056)

Prunasin is found in almond. Prunasin is isolated from kernels of Prunus species, immature fruits of Passiflora species and leaves of perilla (Perilla...

Isoquercitrin

Formula: C21H20O12 (464.0955)

Isoquercitrin is found in alcoholic beverages. Isoquercitrin occurs widely in plants. Isoquercitrin is present in red wine.Isoquercitin can be isolate...

Linolenelaidic acid

Formula: C18H30O2 (278.2246)

Linolenelaidic acid is found in fats and oils. Linolenelaidic acid is isolated from seed oil of safflower (Carthamus tinctorius

Geranial

Formula: C10H16O (152.1201)

Geranial, also known as 3,7-dimethyl-2,6-octadienal, citral or lemonal, belongs to the class of organic compounds known as acyclic monoterpenoids. The...

Amygdalin

Formula: C20H27NO11 (457.1584)

Amygdalin is found in almond. Bitter glycoside of the Rosaceae, found especially in kernels of cherries, peaches and apricots. Amygdalin is present in...

Linoelaidic acid

Formula: C18H32O2 (280.2402)

Linoelaidic acid is an isomer of linoleic acid, or conjugated linoleic acid (CLA), a derivative of a fatty acid linoleic acid. Conjugated linoleic aci...

beta-Ionone

Formula: C13H20O (192.1514)

beta-Ionone, also known as (e)-b-ionone or trans-beta-ionone, belongs to the class of organic compounds known as sesquiterpenoids. These are terpenes ...

Palmitelaidic acid

Formula: C16H30O2 (254.2246)

Palmitelaidic acid is a trans fatty acid (the trans isomer of palmitoleic acid). Trans fatty acids are known to cause changes in plasma lipids and lip...

Octadecanoic acid

Formula: C18H36O2 (284.2715)

Stearic acid, also known as octadecanoic acid or C18:0, belongs to the class of organic compounds known as long-chain fatty acids. These are fatty aci...

Icosanoic acid

Formula: C20H40O2 (312.3028)

Arachidic acid, also known as icosanoic acid, is a saturated fatty acid with a 20-carbon chain. It is a minor constituent of butter, perilla oil, pean...

Tetradecanoic acid

Formula: C14H28O2 (228.2089)

Myristic acid, also known as tetradecanoic acid or C14:0, belongs to the class of organic compounds known as long-chain fatty acids. These are fatty a...

p-Cymene

Formula: C10H14 (134.1095)

Cymene, or p-cymene also known as p-cymol or isopropyltoluene, is a naturally occurring aromatic organic compound. It is classified as a hydrocarbon r...

Citrate

Formula: C6H8O7 (192.027)

Citric acid (citrate) is a tricarboxylic acid, an organic acid with three carboxylate groups. Citrate is an intermediate in the TCA cycle (also known...

(-)-Linalool

Formula: C10H18O (154.1358)

(-)-Linalool

(R)-(+)-alpha-Terpineol

Formula: C10H18O (154.1358)

alpha-Terpineol (CAS: 98-55-5) is a naturally occurring monoterpene alcohol that has been isolated from a variety of sources such as cajuput oil, pine...

Poriferasterol

Formula: C29H48O (412.3705)

Poriferasterol

Aldobionic acid

Formula: C12H20O12 (356.0955)

Aldobionic acid, also known as beta-D-glca-(1->6)-beta-D-gal or glcab1-6galb, is a member of the class of compounds known as O-glucuronides. O-glucuro...

(R)-gamma-Decalactone

Formula: C10H18O2 (170.1307)

(R)-gamma-Decalactone

Mahuannin A

Formula: C30H24O10 (544.1369)

From Prunus subspecies Mahuannin A is found in fruits and apricot.

4-Methylpentanal

Formula: C6H12O (100.0888)

4-Methylpentanal is an intermediate in the metabolism of C21-Steroid hormone. It is a substrate for Cytochrome P450 11A1 (mitochondrial).

(E)-2-Hexenal

Formula: C6H10O (98.0732)

2-Hexenal (CAS: 505-57-7), also known as 2-hexenaldehyde or 3-propylacrolein, belongs to the class of organic compounds known as medium-chain aldehyde...

Flavoxanthin

Formula: C40H56O3 (584.4229)

Flavoxanthin is found in alcoholic beverages. Flavoxanthin is a constituent of Taraxacum officinale (dandelion) Flavoxanthin is a natural xanthophyll ...

xi-Dihydro-5-octyl-2(3H)-furanone

Formula: C12H22O2 (198.162)

xi-Dihydro-5-octyl-2(3H)-furanone is found in alcoholic beverages. xi-Dihydro-5-octyl-2(3H)-furanone is present in orange peel oil, various fruits, ku...

2-Hexen-1-ol

Formula: C6H12O (100.0888)

2-Hexen-1-ol (CAS: 2305-21-7), also known as 2-hexenyl alcohol, belongs to the class of organic compounds known as fatty alcohols. These are aliphatic...

Linalyl oxide

Formula: C10H18O2 (170.1307)

Linalyl oxide is found in citrus. Linalyl oxide is isolated from Citrus paradisi (grapefruit), Thea sinensis (tea) and many other sources. Linalyl oxi...

Gibberellin A3

Formula: C19H22O6 (346.1416)

Gibberellic acid, also known as gibberellin A3, GA, or GA3, is a very potent hormone whose natural occurrence in plants controls their development. Si...

Gibberellin A1

Formula: C19H24O6 (348.1573)

Gibberellin A1

Bergapten

Formula: C12H8O4 (216.0423)

Bergapten, also known as O-methylbergaptol or heraclin, belongs to the class of organic compounds known as 5-methoxypsoralens. These are psoralens con...

Imperatorin

Formula: C16H14O4 (270.0892)

Imperatorin is found in anise. Imperatorin is present in Aegle marmelos (bael fruit) and seeds of Pastinaca sativa (parsnip).Imperatorin is a furocoum...

Phellopterin

Formula: C17H16O5 (300.0998)

Phellopterin is a member of psoralens. A naturally occurring furanocoumarin found in roots of Angelica dahurica and in Seseli elatum (L579). Furocoum...

Aromatic aldehyde

Formula: C7H6O (106.0419)

An arenecarbaldehyde that consists of benzene bearing a single formyl substituent; the simplest aromatic aldehyde and parent of the class of benzaldeh...

Sulcatone

Formula: C8H14O (126.1045)

Sulcatone, also known as methylheptenone or fema 2707, belongs to the class of organic compounds known as ketones. These are organic compounds in whic...

Dimethyl disulfide

Formula: C2H6S2 (93.9911)

Dimethyldisulfide is a volatile organic compound. Methyl disulfide is occasionally found as a volatile component of normal human breath and biofluids....

Indole

Formula: C8H7N (117.0578)

Indole is an aromatic heterocyclic organic compound. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered n...

Acetaldehyde

Formula: C2H4O (44.0262)

Acetaldehyde, also known as ethanal, belongs to the class of organic compounds known as short-chain aldehydes. These are an aldehyde with a chain leng...

Acetone

Formula: C3H6O (58.0419)

Acetone, or propanone, is an organic compound with the formula (CH3)2CO. It is the simplest and smallest ketone. It is a colourless, highly volatile a...

4-Cresol

Formula: C7H8O (108.0575)

para-Cresol, also 4-methylphenol, is an organic compound with the formula CH3C6H4(OH). P-cresol is a cresol that consists of toluene substituted by a ...

Ethyl acetate

Formula: C4H8O2 (88.0524)

Ethyl acetate, also known as 1-acetoxyethane or acetic ester, belongs to the class of organic compounds known as carboxylic acid esters. These are car...

Bisucaberin

Formula: C18H32N4O6 (400.2322)

1,12-Dihydroxy-1,6,12,17-tetraazacyclodocosane-2,5,13,16-tetrone is a keratan 6'-sulfate and an azamacrocycle. Bisucaberin has been reported in Strep...

1-methylpseudouridine

Formula: C10H14N2O6 (258.0852)

A methylpseudouridine in which the methyl group is located at position N-1 on the uracil ring." []