Microbial Natural Product
Microbial natural products, primarily secondary metabolites produced by bacteria, fungi, and other microorganisms, remain a cornerstone of modern medicine and biotechnology. They form the foundation of numerous antibiotics (e.g., penicillin, streptomycin), anticancer agents, and immunosuppressants, addressing critical global health challenges like infectious diseases and cancer. Despite historical challenges such as compound rediscovery and complex biosynthesis, advances in genomics, metabolomics, and synthetic biology are unlocking novel chemical diversity from underexplored microbial sources. Consequently, microbial natural products continue to represent an unparalleled reservoir for discovering next-generation therapeutics, underscoring their enduring significance in drug development and sustainable bioprospecting. (98 words)
Chlorogenate
Chlorogenic acid is an ester of caffeic acid and quinic acid. Chlorogenic acid is the major polyphenolic compound in coffee, isolated from the leaves ...
beta-Caryophyllene
beta-Caryophyllene, also known as caryophyllene or (−)-β-caryophyllene, is a natural bicyclic sesquiterpene that is a constituent of many essential oi...
Dicaffeoylquinic acid
Dicaffeoylquinic acid is a polyphenol compound found in foods of plant origin (PMID: 20428313)
Quercetin 3-O-(6''-acetyl-glucoside)
Quercetin 3-O-(6''-acetyl-glucoside) is a polyphenol compound found in foods of plant origin (PMID: 20428313)
Fukinolic acid
Fukinolic acid is found in green vegetables. Fukinolic acid is from Petasites japonicus (sweet coltsfoot) and Cimicifuga racemos
Petasitenine
Petasitenine is found in giant butterbur. Petasitenine is an alkaloid from Petasites japonicus (sweet coltsfoot
Luteolin 7-methyl ether
Luteolin 7-methyl ether is found in common sage. Luteolin 7-methyl ether is isolated from Salvia officinalis (sage).
Senkirkine
Senkirkine is a macrolide. Senkirkine is a natural product found in Senecio rodriguezii, Farfugium japonicum, and other organisms with data available...
Hex-3-en-1-al
Cis-Hex-3-en-1-ol or (Z)-3-Hexen-1-ol, also known as (3Z)-hex-3-en-1-ol or leaf alcohol, belongs to the class of organic compounds known as fatty alco...
3,4-Dihydroxyphenacyl caffeate
3,4-Dihydroxyphenacyl caffeate is found in green vegetables. 3,4-Dihydroxyphenacyl caffeate is a constituent of the rhizomes of Petasites japonicus (s...
Tiglic acid
Tiglic acid is a monocarboxylic unsaturated organic acid. It is found in croton oil and in several other natural products. It has also been isolated f...
Bakkenolide D
Bakkenolide D is found in giant butterbur. Bakkenolide D is a constituent of Petasites japonicus (sweet coltsfoot)
Hexobarbitone
Formula: C12H16N2O3 (236.1161)
Hexobarbital is only found in individuals that have used or taken this drug. It is a barbiturate that is effective as a hypnotic and sedative. [PubChe...
1,2-Dimethoxybenzene
1,2-Dimethoxybenzene, commonly known as veratrole, is a chemical compound with the formula C6H4(OCH3)2. It is the dimethyl ether derived from pyrocate...
Furanoeremophilane
Furanoeremophilane is found in giant butterbur. Furanoeremophilane is a constituent of Petasites japonicus (sweet coltsfoot)
Epoxyeremopetasinorol
Epoxyeremopetasinorol is found in green vegetables. Epoxyeremopetasinorol is a constituent of Petasites japonicus (sweet coltsfoot)
Ingenol mebutate
Ingenol mebutate is a tetracyclic diterpenoid ester obtained by formal condensation of the carboxy group of (2Z)-2-methylbut-2-enoic (angelic) acid wi...
Bakkenolide B
Bakkenolide E is found in giant butterbur. Bakkenolide E is a constituent of Petasites japonicus (sweet coltsfoot).
Bakkenolide A
Bakkenolide A is a sesquiterpenoid. Bakkenolide A is a natural product found in Ligularia kanaitzensis, Ligularia dolichobotrys, and other organisms ...
Furanofukinin
Furanofukinin is found in giant butterbur. Furanofukinin is a constituent of Petasites japonicus (sweet coltsfoot).
S-Furanopetasitin
S-Furanopetasitin is found in giant butterbur. S-Furanopetasitin is a constituent of Petasites japonicus (sweet coltsfoot)
Petasinine
Petasinine is found in green vegetables. Petasinine is an alkaloid from Petasites japonicus (sweet coltsfoot
Petasitolone
Petasitolone is found in burdock. Petasitolone is a constituent of Petasites japonicus (sweet coltsfoot).
Petasalbin
Petasalbin is found in giant butterbur. Petasalbin is a constituent of coltsfoot and Petasites japonicus (sweet coltsfoot)
Eremophilenolide
Eremophilenolide is a sesquiterpene lactone. Eremophilenolide has been reported in Petasites japonicus, Petasites hybridus, and Petasites albus with ...
(3beta,6beta)-Furanoeremophilane-3,6-diol
(3beta,6beta)-Furanoeremophilane-3,6-diol is found in giant butterbur. (3beta,6beta)-Furanoeremophilane-3,6-diol is a constituent of Petasites japonic...
Eremopetasinorone A
Eremopetasinorone B is found in green vegetables. Eremopetasinorone B is a constituent of Petasites japonicus (sweet coltsfoot)
Furanojaponin
Furanojaponin is found in giant butterbur. Furanojaponin is a constituent of Petasites japonicus (sweet coltsfoot)
Dihydrofukinolide
Dihydrofukinolide is found in giant butterbur. Dihydrofukinolide is a constituent of Petasites japonicus (sweet coltsfoot)
Isopenicillin N
Formula: C14H21N3O6S (359.1151)
Isopenicillin N is a penicillin. It is a conjugate acid of an isopenicillin N(1-). Isopenicillin N is a natural product found in Sarocladium strictum...
delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine
Formula: C14H25N3O6S (363.1464)
A tripeptoid arising from cleavage of both rings of a penicillin derivative." []
Eleutheroside A
Daucosterol is a steroid saponin that is sitosterol attached to a beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. It has bee iso...
Methylparaben
Methylparaben, also known as methyl 4-hydroxybenzoate or p-carbomethoxyphenol, belongs to the class of organic compounds known as p-hydroxybenzoic aci...
4-Hydroxybenzoate
4-Hydroxybenzoic acid, also known as p-hydroxybenzoate or 4-carboxyphenol, belongs to the class of organic compounds known as hydroxybenzoic acid deri...
Indole-3-carboxylate
Indole-3-carboxylic acid, also known as 3-carboxyindole or 3-indolecarboxylate, belongs to the class of organic compounds known as indolecarboxylic ac...
3,4-Dihydroxybenzaldehyde
3,4-Dihydroxybenzaldehyde, also known as protocatechuic aldehyde, is a phenolic aldehyde, a compound released from cork stoppers into wine. This molec...