EC: 6.4.1.2

acetyl-CoA carboxylase (acetyl-CoA:hydrogencarbonate ligase (ADP-forming))

enzyme lambda metabolic reaction experiment
uniprot:P11029 [Citrate]

Hydrogencarbonate + Acetyl_CoA + ATP -> ADP + Phosphate + Malonyl_CoA		 (( (( (( (E * A) ) * B) ) * C) ) / (( (( (( (( (( (( (( (( (( (Phi_0 * A) ) * B) ) * C) ) + (( (Phi_a * B) ) * C)) ) + (( (Phi_b * A) ) * C)) ) + (( (Phi_c * A) ) * B)) ) + (Phi_ab * C)) ) + (Phi_bc * A)) ) + (Phi_ac * B)) ) + Phi_abc)) buffer: 50 mM morpholinopropanesulfonic acid, 10 mM potassium citrate, 10 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:P11029 [Citrate]

Hydrogencarbonate + ATP + Acetyl_CoA -> Phosphate + Malonyl_CoA + ADP		 (( (( (( (( (E * kcat) ) * A) ) * B) ) * C) ) / (( (( (( (( (( (( (K_ABC + (K_BC * A)) ) + (K_AC * B)) ) + (K_AB * C)) ) + (( (Km_C * A) ) * B)) ) + (( (Km_B * A) ) * C)) ) + (( (Km_A * B) ) * C)) ) + (( (A * B) ) * C))) buffer: 50 mM morpholinopropanesulfonic acid, 10 mM potassium citrate, 10 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:O00763 [acetyl-CoA carboxylase(Enzyme) wildtype ACC2]

ATP + Acetyl_CoA + Hydrogencarbonate -> Phosphate + Malonyl_CoA + ADP		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 10 mM MgCl2, 10 mM sodium citrate, 0.5% DMSO
PH: 7
Temperature: 37
uniprot:O00763 [acetyl-CoA carboxylase(Enzyme) wildtype ACC2]

ATP + Hydrogencarbonate + Acetyl_CoA -> Phosphate + Malonyl_CoA + ADP		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 10 mM MgCl2, 10 mM sodium citrate, 0.5% DMSO
PH: 7
Temperature: 37
uniprot:O00763 [acetyl-CoA carboxylase(Enzyme) wildtype ACC2]

Hydrogencarbonate + Acetyl_CoA + ATP -> ADP + Malonyl_CoA + Phosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 10 mM MgCl2, 10 mM sodium citrate, 0.5% DMSO
PH: 7
Temperature: 37
uniprot:Q1HEC0 [acetyl-CoA carboxylase(Enzyme) wildtype ACC2]

Hydrogencarbonate + Acetyl_CoA + ATP -> Phosphate + ADP + Malonyl_CoA		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 10 mM MgCl2, 10 mM sodium citrate, 0.5% DMSO
PH: 7
Temperature: 37
uniprot:Q1HEC0 [acetyl-CoA carboxylase(Enzyme) wildtype ACC2]

Hydrogencarbonate + ATP + Acetyl_CoA -> Phosphate + Malonyl_CoA + ADP		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 10 mM MgCl2, 10 mM sodium citrate, 0.5% DMSO
PH: 7
Temperature: 37
uniprot:Q1HEC0 [acetyl-CoA carboxylase(Enzyme) wildtype ACC2]

Acetyl_CoA + Hydrogencarbonate + ATP -> Malonyl_CoA + ADP + Phosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 10 mM MgCl2, 10 mM sodium citrate, 0.5% DMSO
PH: 7
Temperature: 37
uniprot:Q13085 [acetyl-CoA carboxylase(Enzyme) wildtype ACC1]

Hydrogencarbonate + Acetyl_CoA + ATP -> ADP + Malonyl_CoA + Phosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 10 mM MgCl2, 10 mM sodium citrate, 0.5% DMSO
PH: 7
Temperature: 37
uniprot:Q13085 [acetyl-CoA carboxylase(Enzyme) wildtype ACC1]

Acetyl_CoA + Hydrogencarbonate + ATP -> Phosphate + Malonyl_CoA + ADP		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 10 mM MgCl2, 10 mM sodium citrate, 0.5% DMSO
PH: 7
Temperature: 37
uniprot:Q13085 [acetyl-CoA carboxylase(Enzyme) wildtype ACC1]

Acetyl_CoA + Hydrogencarbonate + ATP -> Phosphate + Malonyl_CoA + ADP		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 10 mM MgCl2, 10 mM sodium citrate, 0.5% DMSO
PH: 7
Temperature: 37
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

ATP + Acetyl_CoA + Hydrogencarbonate -> Malonyl_CoA + ADP + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

Hydrogencarbonate + Acetyl_CoA + ATP -> Phosphate + Malonyl_CoA + ADP		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

ATP + Acetyl_CoA + Hydrogencarbonate -> ADP + Phosphate + Malonyl_CoA		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

Acetyl_CoA + Hydrogencarbonate + ATP -> Phosphate + Malonyl_CoA + ADP		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

ATP + Acetyl_CoA + Hydrogencarbonate -> Phosphate + ADP + Malonyl_CoA		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

Propanoyl_CoA + ATP + Hydrogencarbonate -> (S)_2_Methyl_3_oxopropanoyl_CoA + Phosphate + ADP		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

Hydrogencarbonate + Propanoyl_CoA + ATP -> Phosphate + ADP + (S)_2_Methyl_3_oxopropanoyl_CoA		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

ATP + Hydrogencarbonate + Propanoyl_CoA -> ADP + (S)_2_Methyl_3_oxopropanoyl_CoA + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

Hydrogencarbonate + Propanoyl_CoA + ATP -> (S)_2_Methyl_3_oxopropanoyl_CoA + ADP + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

Hydrogencarbonate + Propanoyl_CoA + ATP -> Phosphate + (S)_2_Methyl_3_oxopropanoyl_CoA + ADP		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

Hydrogencarbonate + Propanoyl_CoA + ATP -> (S)_2_Methyl_3_oxopropanoyl_CoA + ADP + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

Hydrogencarbonate + ATP + Acetyl_CoA -> Malonyl_CoA + ADP + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

ATP + Acetyl_CoA + Hydrogencarbonate -> ADP + Phosphate + Malonyl_CoA		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

ATP + Hydrogencarbonate + Acetyl_CoA -> Phosphate + ADP + Malonyl_CoA		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

ATP + Hydrogencarbonate + Acetyl_CoA -> Malonyl_CoA + Phosphate + ADP		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

ATP + Hydrogencarbonate + Acetyl_CoA -> ADP + Malonyl_CoA + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

Hydrogencarbonate + Acetyl_CoA + ATP -> Malonyl_CoA + Phosphate + ADP		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

Hydrogencarbonate + Acetyl_CoA + ATP -> ADP + Malonyl_CoA + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

Acetyl_CoA + Hydrogencarbonate + ATP -> Malonyl_CoA + Phosphate + ADP		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

Acetyl_CoA + ATP + Hydrogencarbonate -> ADP + Phosphate + Malonyl_CoA		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

Hydrogencarbonate + Acetyl_CoA + ATP -> ADP + Malonyl_CoA + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

ATP + Hydrogencarbonate + Acetyl_CoA -> Phosphate + ADP + Malonyl_CoA		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

ATP + Acetyl_CoA + Hydrogencarbonate -> Malonyl_CoA + ADP + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Quizalofop]

ATP + Acetyl_CoA + Hydrogencarbonate -> Malonyl_CoA + Phosphate + ADP		 (Vmax / (1 + (( (I / Ki) ) ^ h))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Quizalofop]

Hydrogencarbonate + Acetyl_CoA + ATP -> ADP + Phosphate + Malonyl_CoA		 (Vmax / (1 + (( (I / Ki) ) ^ h))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

ATP + Acetyl_CoA + Hydrogencarbonate -> Phosphate + ADP + Malonyl_CoA		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

ATP + Hydrogencarbonate + Acetyl_CoA -> ADP + Malonyl_CoA + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

Hydrogencarbonate + ATP + Acetyl_CoA -> ADP + Malonyl_CoA + Phosphate		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

Hydrogencarbonate + Acetyl_CoA + ATP -> Phosphate + Malonyl_CoA + ADP		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

ATP + Hydrogencarbonate + Acetyl_CoA -> Malonyl_CoA + Phosphate + ADP		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 1]

Hydrogencarbonate + Acetyl_CoA + ATP -> Phosphate + ADP + Malonyl_CoA		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype ACCase 2]

Hydrogencarbonate + ATP + Acetyl_CoA -> Phosphate + Malonyl_CoA + ADP		 (( (Vmax * A) ) / (A + Km)) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Quizalofop]

Hydrogencarbonate + ATP + Acetyl_CoA -> ADP + Phosphate + Malonyl_CoA		 (Vmax / (1 + (( (I / Ki) ) ^ h))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Quizalofop]

Acetyl_CoA + ATP + Hydrogencarbonate -> Malonyl_CoA + ADP + Phosphate		 (Vmax / (1 + (( (I / Ki) ) ^ h))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Quizalofop]

ATP + Acetyl_CoA + Hydrogencarbonate -> Phosphate + ADP + Malonyl_CoA		 (Vmax / (1 + (( (I / Ki) ) ^ h))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Quizalofop]

ATP + Acetyl_CoA + Hydrogencarbonate -> ADP + Phosphate + Malonyl_CoA		 (Vmax / (1 + (( (I / Ki) ) ^ h))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Fluazifop]

Acetyl_CoA + Hydrogencarbonate + ATP -> Phosphate + ADP + Malonyl_CoA		 (Vmax / (1 + (( (I / Ki) ) ^ h))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Quizalofop]

Hydrogencarbonate + ATP + Acetyl_CoA -> Phosphate + ADP + Malonyl_CoA		 (Vmax / (1 + (I / Ki))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Quizalofop]

ATP + Hydrogencarbonate + Acetyl_CoA -> Phosphate + Malonyl_CoA + ADP		 (Vmax / (1 + (I / Ki))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Quizalofop]

ATP + Acetyl_CoA + Hydrogencarbonate -> ADP + Malonyl_CoA + Phosphate		 (Vmax / (1 + (I / Ki))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Quizalofop]

Acetyl_CoA + ATP + Hydrogencarbonate -> ADP + Malonyl_CoA + Phosphate		 (Vmax / (1 + (I / Ki))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Fluazifop]

Acetyl_CoA + Hydrogencarbonate + ATP -> ADP + Phosphate + Malonyl_CoA		 (Vmax / (1 + (( (I / Ki) ) ^ h))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Fluazifop]

ATP + Hydrogencarbonate + Acetyl_CoA -> ADP + Phosphate + Malonyl_CoA		 (Vmax / (1 + (( (I / Ki) ) ^ h))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [Fluazifop]

Acetyl_CoA + ATP + Hydrogencarbonate -> ADP + Malonyl_CoA + Phosphate		 (Vmax / (1 + (( (I / Ki) ) ^ h))) buffer: 100 mM Hepes/KOH, 5 mM MgCl2
PH: 8
Temperature: 30
- [acetyl-CoA carboxylase(Enzyme) wildtype AccAD]

Malonyl_CoA + Holo_[carboxylase] -> Acetyl_CoA + Carboxybiotin_carboxyl_carrier_protein		 (( (Vmax * B) ) / (Km + B)) buffer: 100 mM Tris-Cl, 10 mM L-malate, 0.5 mM NAD, 0.06 % bovine serum albumin, 0.1 mg/ml citrate synthase, 0.07 mg/ml malic dehydrogenase
PH: 8
Temperature: 22
- [acetyl-CoA carboxylase(Enzyme) wildtype AccAD]

Malonyl_CoA + Holo_[carboxylase] -> Carboxybiotin_carboxyl_carrier_protein + Acetyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 10 mM L-malate, 0.5 mM NAD, 0.06 % bovine serum albumin, 0.1 mg/ml citrate synthase, 0.07 mg/ml malic dehydrogenase
PH: 8
Temperature: 22
- [acetyl-CoA carboxylase(Enzyme) wildtype AccAD]

Holo_[carboxylase] + Malonyl_CoA -> Acetyl_CoA + Carboxybiotin_carboxyl_carrier_protein		 (( (Vmax * B) ) / (Km + B)) buffer: 100 mM Tris-Cl, 10 mM L-malate, 0.5 mM NAD, 0.06 % bovine serum albumin, 0.1 mg/ml citrate synthase, 0.07 mg/ml malic dehydrogenase
PH: 8
Temperature: 22
- [Moiramide B]

Malonyl_CoA + Holo_[carboxylase] -> Carboxybiotin_carboxyl_carrier_protein + Acetyl_CoA		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 100 mM Tris-Cl, 10 mM L-malate, 0.5 mM NAD, 0.06 % bovine serum albumin, 0.1 mg/ml citrate synthase, 0.07 mg/ml malic dehydrogenase
PH: 8
Temperature: 22
- [acetyl-CoA carboxylase(Enzyme) wildtype AccAD]

Holo_[carboxylase] + Malonyl_CoA -> Carboxybiotin_carboxyl_carrier_protein + Acetyl_CoA		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 10 mM L-malate, 0.5 mM NAD, 0.06 % bovine serum albumin, 0.1 mg/ml citrate synthase, 0.07 mg/ml malic dehydrogenase
PH: 8
Temperature: 22

Pathways

pathway id name
BioCyc:HUMAN_PWY0-1264 biotin-carboxyl carrier protein assembly
BioCyc:YEAST_PWY0-1264 biotin-carboxyl carrier protein assembly
PathBank:SMP0000785 Biotin Metabolism
PathBank:SMP0002079 Biotin-Carboxyl Carrier Protein Assembly
PlantCyc:ARA_PWY0-1264 biotin-carboxyl carrier protein assembly
Reactome:R-DDI-75105 Fatty acyl-CoA biosynthesis
Reactome:R-DDI-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-DDI-196780 Biotin transport and metabolism
Reactome:R-HSA-75105 Fatty acyl-CoA biosynthesis
Reactome:R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-HSA-196780 Biotin transport and metabolism
Reactome:R-HSA-1643685 Disease
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-MMU-75105 Fatty acyl-CoA biosynthesis
Reactome:R-MMU-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-MMU-196780 Biotin transport and metabolism
Reactome:R-RNO-8978868 Fatty acid metabolism
Reactome:R-RNO-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-RNO-196780 Biotin transport and metabolism
Reactome:R-SCE-75105 Fatty acyl-CoA biosynthesis
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-75105 Fatty acyl-CoA biosynthesis
Reactome:R-DDI-8978868 Fatty acid metabolism
Reactome:R-DDI-196854 Metabolism of vitamins and cofactors
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-8978868 Fatty acid metabolism
Reactome:R-HSA-2426168 Activation of gene expression by SREBF (SREBP)
Reactome:R-HSA-163765 ChREBP activates metabolic gene expression
Reactome:R-HSA-196854 Metabolism of vitamins and cofactors
Reactome:R-HSA-3296482 Defects in vitamin and cofactor metabolism
Reactome:R-HSA-3371599 Defective HLCS causes multiple carboxylase deficiency
Reactome:R-MMU-8978868 Fatty acid metabolism
Reactome:R-MMU-196854 Metabolism of vitamins and cofactors
Reactome:R-RNO-196854 Metabolism of vitamins and cofactors
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-8978868 Fatty acid metabolism
Reactome:R-SCE-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-SCE-196780 Biotin transport and metabolism
Reactome:R-SPO-8978868 Fatty acid metabolism
Reactome:R-HSA-5668914 Diseases of metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-556833 Metabolism of lipids
Reactome:R-RNO-75105 Fatty acyl-CoA biosynthesis
Reactome:R-SCE-556833 Metabolism of lipids
Reactome:R-SPO-196854 Metabolism of vitamins and cofactors
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DDI-556833 Metabolism of lipids
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-8957322 Metabolism of steroids
Reactome:R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF)
Reactome:R-HSA-163685 Integration of energy metabolism
Reactome:R-HSA-3323169 Defects in biotin (Btn) metabolism
Reactome:R-SCE-196854 Metabolism of vitamins and cofactors
Reactome:R-SPO-556833 Metabolism of lipids
Reactome:R-SPO-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-SPO-196780 Biotin transport and metabolism
WikiPathways:WP5287 17q12 copy number variation syndrome
WikiPathways:WP5031 Biotin metabolism, including IMDs
WikiPathways:WP5066 FOXA2 pathway
PathBank:SMP0120460 Biotinidase Deficiency
PathBank:SMP0000016 Propanoate Metabolism
PathBank:SMP0000174 Biotinidase Deficiency
PathBank:SMP0000334 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
PathBank:SMP0000564 Multiple Carboxylase Deficiency, Neonatal or Early Onset Form
PathBank:SMP0087286 Biotin Metabolism
PathBank:SMP0120628 Multiple Carboxylase Deficiency, Neonatal or Early Onset Form
PathBank:SMP0120946 LPS and Citrate Signaling and Inflammation
PathBank:SMP0121263 Biotin Metabolism
PathBank:SMP0000196 Leigh Syndrome
PathBank:SMP0000201 Methylmalonic Aciduria Due to Cobalamin-Related Disorders
PathBank:SMP0000559 Pyruvate Kinase Deficiency
PathBank:SMP0087257 Fatty Acid Biosynthesis
PathBank:SMP0087377 Biotin Metabolism
PathBank:SMP0120680 Biotinidase Deficiency
PathBank:SMP0000212 Pyruvate Dehydrogenase Complex Deficiency
PathBank:SMP0087183 Biotin Metabolism
PathBank:SMP0087231 Pyruvate Metabolism
PathBank:SMP0087248 Propanoate Metabolism
PathBank:SMP0063602 Biotin Metabolism
PathBank:SMP0100046 LPS and Citrate Signaling and Inflammation
PathBank:SMP0120847 Multiple Carboxylase Deficiency, Neonatal or Early Onset Form
PathBank:SMP0122242 Biotin-Carboxyl Carrier Protein Assembly
PathBank:SMP0000060 Pyruvate Metabolism
PathBank:SMP0000066 Biotin Metabolism
PathBank:SMP0000456 Fatty Acid Biosynthesis
PathBank:SMP0000198 Malonic Aciduria
PathBank:SMP0000502 Malonyl-CoA Decarboxylase Deficiency
PathBank:SMP0000558 Primary Hyperoxaluria II, PH2
PathBank:SMP0002304 TCA Cycle
PathBank:SMP0002355 Pyruvate Metabolism