EC: 3.6.1.22

NAD+ diphosphatase (NAD+ phosphohydrolase)

enzyme lambda metabolic reaction experiment
uniprot:Q9CA40 [Mn2+]

NADH + H2O -> Reduced_nicotinamide_nucleotide + AMP
(( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris, 1 mM DTT, 20-40 U/ml alkaline phosphatase
PH: 7
Temperature: 37
uniprot:Q8JZU0 [Mn2+]

H2O + NADH -> Reduced_nicotinamide_nucleotide + AMP
(( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM dithiothreitol, 5 U/ml alkaline phosphatase
PH: 8
Temperature: 37

Pathways

pathway id name
BioCyc:ARA_PWY-6612 superpathway of tetrahydrofolate biosynthesis
BioCyc:ARA_PWY-6502 oxidized GTP and dGTP detoxification
BioCyc:ARA_PWY-6147 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I
BioCyc:ARA_PWY-5381 pyridine nucleotide cycling (plants)
BioCyc:MTBH37RV_NAD-BIOSYNTHESIS-II NAD salvage pathway III (to nicotinamide riboside)
BioCyc:MOUSE_PWY66-5 superpathway of cholesterol biosynthesis
BioCyc:META_PWY-6502 oxidized GTP and dGTP detoxification
BioCyc:META_PWY-6612 superpathway of tetrahydrofolate biosynthesis
BioCyc:ARA_PWY-3742 tetrahydrofolate biosynthesis II
BioCyc:MTBH37RV_PYRIDNUCSAL-PWY NAD salvage pathway I (PNC VI cycle)
BioCyc:MTBCDC1551_PYRIDNUCSAL-PWY NAD salvage pathway I
BioCyc:MOUSE_PWY-5123 trans, trans-farnesyl diphosphate biosynthesis
BioCyc:META_PWY-6147 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I
BioCyc:YEAST_PERIPLASMA-NAD-DEGRADATION periplasmic NAD degradation
BioCyc:ECOL199310_PYRIDNUCSAL-PWY NAD salvage pathway I
BioCyc:MOUSE_PWY-922 mevalonate pathway I
BioCyc:MOUSE_NAD-BIOSYNTHESIS-II NAD salvage pathway II
BioCyc:MOUSE_PYRNUCYC-PWY pyridine nucleotide cycling
PlantCyc:ARA_PWY-3742 tetrahydrofolate biosynthesis II
PlantCyc:ARA_PWY-5381 pyridine nucleotide cycling (plants)
PlantCyc:PLANT_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:ARA_PWY-6147 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I
PlantCyc:PLANT_PWY-6147 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I
PlantCyc:ARA_PWY-6502 oxidized GTP and dGTP detoxification
PlantCyc:ARA_PWY-6612 superpathway of tetrahydrofolate biosynthesis
PlantCyc:PLANT_PWY-3742 tetrahydrofolate biosynthesis II
PlantCyc:PLANT_PWY-6612 superpathway of tetrahydrofolate biosynthesis
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-196807 Nicotinate metabolism
Reactome:R-CEL-196807 Nicotinate metabolism
Reactome:R-DRE-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-RNO-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-SCE-196807 Nicotinate metabolism
Reactome:R-SPO-1430728 Metabolism
Reactome:R-BTA-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-CEL-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-DRE-196854 Metabolism of vitamins and cofactors
Reactome:R-DRE-196843 Vitamin B2 (riboflavin) metabolism
Reactome:R-HSA-196854 Metabolism of vitamins and cofactors
Reactome:R-HSA-196843 Vitamin B2 (riboflavin) metabolism
Reactome:R-MMU-196854 Metabolism of vitamins and cofactors
Reactome:R-MMU-196843 Vitamin B2 (riboflavin) metabolism
Reactome:R-RNO-196854 Metabolism of vitamins and cofactors
Reactome:R-RNO-196843 Vitamin B2 (riboflavin) metabolism
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-SPO-196807 Nicotinate metabolism
Reactome:R-DRE-1430728 Metabolism
Reactome:R-HSA-196807 Nicotinate metabolism
Reactome:R-MMU-196807 Nicotinate metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-SPO-196854 Metabolism of vitamins and cofactors
Reactome:R-BTA-196854 Metabolism of vitamins and cofactors
Reactome:R-CEL-1430728 Metabolism
Reactome:R-CEL-196854 Metabolism of vitamins and cofactors
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-15869 Nucleotide metabolism
Reactome:R-HSA-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-MMU-15869 Nucleotide metabolism
Reactome:R-MMU-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-SCE-196854 Metabolism of vitamins and cofactors
Reactome:R-SPO-196849 Metabolism of water-soluble vitamins and cofactors
WikiPathways:WP5037 Riboflavin and CoQ disorders
PathBank:SMP0000070 Riboflavin Metabolism
PathBank:SMP0087306 Riboflavin Metabolism
PathBank:SMP0087241 Nicotinate and Nicotinamide Metabolism
PathBank:SMP0012013 Pterin Biosynthesis (Folate Precursor)
PathBank:SMP0000048 Nicotinate and Nicotinamide Metabolism