数据之源，洞见之始

squalene + reduced [NADPH—hemoprotein reductase] + O₂ <=> (S)-2,3-epoxysqualene + oxidized [NADPH—hemoprotein reductase] + H₂O + H⁺

= Squalene[C30H50] + [] + Oxygen[O2] + (S)-2,3-Epoxysqualene[C30H50O] + [] + H2O[H2O] + H+[H]

DB Links

• KEGG: R02874
• EC Number: 1.14.14.17
• Rhea: RHEA:25285

Alias

• [Rhea:RHEA:25283] squalene + reduced [NADPH—hemoprotein reductase] + O₂ => (S)-2,3-epoxysqualene + oxidized [NADPH—hemoprotein reductase] + H₂O + H⁺
• [Rhea:RHEA:25284] (S)-2,3-epoxysqualene + oxidized [NADPH—hemoprotein reductase] + H₂O + H⁺ => squalene + reduced [NADPH—hemoprotein reductase] + O₂
• [Rhea:RHEA:25285] squalene + reduced [NADPH—hemoprotein reductase] + O₂ <=> (S)-2,3-epoxysqualene + oxidized [NADPH—hemoprotein reductase] + H₂O + H⁺
• [Rhea:RHEA:58917] squalene + 2 Fe(II)-[cytochrome b₅] + O₂ + 2 H⁺ => (S)-2,3-epoxysqualene + 2 Fe(III)-[cytochrome b₅] + H₂O
• [Rhea:RHEA:58918] (S)-2,3-epoxysqualene + 2 Fe(III)-[cytochrome b₅] + H₂O => squalene + 2 Fe(II)-[cytochrome b₅] + O₂ + 2 H⁺
• [Rhea:RHEA:58919] squalene + 2 Fe(II)-[cytochrome b₅] + O₂ + 2 H⁺ <=> (S)-2,3-epoxysqualene + 2 Fe(III)-[cytochrome b₅] + H₂O

Metabolites

Substrates

metabolite	compartment	Structure

Products

metabolite	compartment	Structure
Squalene Formula: C30H50	Cytoplasm
Formula:	Cytoplasm
Oxygen Formula: O2	Cytoplasm
(S)-2,3-Epoxysqualene Formula: C30H50O	Cytoplasm
Formula:	Cytoplasm
H2O Formula: H2O	Cytoplasm
H+ Formula: H	Cytoplasm