Rhea:RHEA:13558
γ-L-glutamyl-L-cysteine + glycine + ATP => glutathione + ADP + phosphate + H+
= L-gamma-glutamyl-L-cysteinate(1-)[C8H13N2O5S] + glycine zwitterion[C2H5NO2] + ATP(4-)[C10H12N5O13P3] + glutathionate(1-)[C10H16N3O6S] + ADP(3-)[C10H12N5O10P2] + hydrogenphosphate[HO4P] + H+[H]
DB Links
- BioCyc: GLUTATHIONE-SYN-RXN
- EC Number: 6.3.2.3
- Rhea: RHEA:13558
- Reactome: R-HSA-174394.5
- MACiE: M0199
Alias
- [Rhea:RHEA:13558] γ-L-glutamyl-L-cysteine + glycine + ATP => glutathione + ADP + phosphate + H+
- [Rhea:RHEA:13559] glutathione + ADP + phosphate + H+ => γ-L-glutamyl-L-cysteine + glycine + ATP
- [Rhea:RHEA:13560] γ-L-glutamyl-L-cysteine + glycine + ATP <=> glutathione + ADP + phosphate + H+
Metabolites
Substrates
| metabolite | compartment | Structure |
|---|
Products
| metabolite | compartment | Structure |
|---|---|---|
| L-gamma-glutamyl-L-cysteinate(1-) Formula: C8H13N2O5S |
Cytoplasm | |
| glycine zwitterion Formula: C2H5NO2 |
Cytoplasm | |
| ATP(4-) Formula: C10H12N5O13P3 |
Cytoplasm | |
| glutathionate(1-) Formula: C10H16N3O6S |
Cytoplasm | |
| ADP(3-) Formula: C10H12N5O10P2 |
Cytoplasm | |
| hydrogenphosphate Formula: HO4P |
Cytoplasm | |
| H+ Formula: H |
Cytoplasm |