BioCyc:GTP-CYCLOHYDRO-I-RXN

This is the first step in the biosynthesis offolic acid.

GTP + WATER --> PROTON + FORMATE + DIHYDRONEOPTERIN-P3

GTP(4-)[C10H12N5O14P3] + H2O[H2O] = H+[H] + Formate[CH2O2] + 7,8-dihydroneopterin 3'-triphosphate(4-)[C9H12N5O13P3]

DB Links

  • BioCyc: GTP-CYCLOHYDRO-I-RXN
  • EC Number: 3.5.4.16
Alias

Metabolites

Substrates
metabolite compartment Structure
GTP(4-)

Formula: C10H12N5O14P3
Cytoplasm
H2O

Formula: H2O
Cytoplasm
Products
metabolite compartment Structure
H+

Formula: H
Cytoplasm
Formate

Formula: CH2O2
Cytoplasm
7,8-dihydroneopterin 3'-triphosphate(4-)

Formula: C9H12N5O13P3
Cytoplasm