BioCyc:RXN-12540
This reaction, which involves hydrogen peroxide and ferrous iron and produces a hydroxyl radical, is known as the Fenton reaction, and was suggested by Haber and Weiss in the 1930s.
In the presence of physiological bicarbonate the product of the Fenton reaction is a |FRAME: CPD-27514| |CITS: [30458276]| (see further |CITS: [39602264]|).
Fenton reaction
Hydrogen peroxide[H2O2] + Fe2+[Fe] = Hydroxyl radical[OH] + HO-[OH] + Fe3+[Fe]
DB Links
- BioCyc: RXN-12540
Alias
Metabolites
Substrates
| metabolite | compartment | Structure |
|---|---|---|
| Hydrogen peroxide Formula: H2O2 |
Cytoplasm | |
| Fe2+ Formula: Fe |
Cytoplasm |
Products
| metabolite | compartment | Structure |
|---|---|---|
| Hydroxyl radical Formula: OH |
Cytoplasm | |
| HO- Formula: OH |
Cytoplasm | |
| Fe3+ Formula: Fe |
Cytoplasm |