DLD2 - Saccharomyces cerevisiae S288C
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2
> DLD2 - Saccharomyces cerevisiae S288C [D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2]
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Metadata
Organism Source: 559292 - Saccharomyces cerevisiae S288C
EC Number: 1.1.2.4 / 1.1.99.40
Cluster:
Registry Model:
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R00197 | (R)-lactate:ferricytochrome-c 2-oxidoreductase | (R)-Lactate + 2 Ferricytochrome c <=> Pyruvate + 2 Ferrocytochrome c + 2 H+ |
| KEGG:R11593 | (R)-2-hydroxyglutarate:pyruvate oxidoreductase [(R)-lactate-forming] | Pyruvate + (R)-2-Hydroxyglutarate <=> (R)-Lactate + 2-Oxoglutarate |
| Rhea:RHEA:13522 | (R)-lactate + 2 Fe(III)-[cytochrome c] => 2 Fe(II)-[cytochrome c] + pyruvate + 2 H+ | |
| Rhea:RHEA:13523 | 2 Fe(II)-[cytochrome c] + pyruvate + 2 H+ => (R)-lactate + 2 Fe(III)-[cytochrome c] | |
| Rhea:RHEA:13524 | (R)-lactate + 2 Fe(III)-[cytochrome c] <=> 2 Fe(II)-[cytochrome c] + pyruvate + 2 H+ | |
| Rhea:RHEA:51609 | (R)-2-hydroxyglutarate + pyruvate => (R)-lactate + 2-oxoglutarate | |
| Rhea:RHEA:51610 | (R)-lactate + 2-oxoglutarate => (R)-2-hydroxyglutarate + pyruvate | |
| Rhea:RHEA:51611 | (R)-2-hydroxyglutarate + pyruvate <=> (R)-lactate + 2-oxoglutarate | |
| Rhea:RHEA:51613 | (R)-2-hydroxyglutarate + oxaloacetate => (R)-malate + 2-oxoglutarate | |
| Rhea:RHEA:51614 | (R)-malate + 2-oxoglutarate => (R)-2-hydroxyglutarate + oxaloacetate | |
| Rhea:RHEA:51615 | (R)-2-hydroxyglutarate + oxaloacetate <=> (R)-malate + 2-oxoglutarate | |
| BioCyc:D-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN | D-LACTATE + 2 Cytochromes-C-Oxidized --> PYRUVATE + 2 Cytochromes-C-Reduced + 2 PROTON | |
| BioCyc:RXN-18432 | R-2-HYDROXYGLUTARATE + PYRUVATE<=>2-KETOGLUTARATE + D-LACTATE | |
| BioCyc:RXN-18433 | R-2-HYDROXYGLUTARATE + OXALACETIC_ACID<=>2-KETOGLUTARATE + CPD-660 |
Pathways
| pathway id | name |
|---|---|
| BioCyc:YEAST_PWY-5386-1 | methylglyoxal catabolism |
| Reactome:R-SCE-1430728 | Metabolism |
| Reactome:R-SCE-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-SCE-880009 | Interconversion of 2-oxoglutarate and 2-hydroxyglutarate |
| PathBank:SMP0002355 | Pyruvate Metabolism |