BIO3-BIO1

K19562 BIO3-BIO1; bifunctional dethiobiotin synthetase / spermidine---8-amino-7-oxononanoate transaminase [EC:6.3.3.3 2.6.1.127]

Protein Function: bifunctional dethiobiotin synthetase / spermidine---8-amino-7-oxononanoate transaminase [EC:6.3.3.3 2.6.1.127]

DBLinks
Proteins
protein id name function taxonomy source
Reactions
reaction id name note
KEGG:R13517 spermidine:8-amino-7-oxononanoate aminotransferase Spermidine + 8-Amino-7-oxononanoate <=> N-(3-Aminopropyl)-4-aminobutanal + 7,8-Diaminononanoate
KEGG:R03182 7,8-diaminononanoate:carbon-dioxide cyclo-ligase two-step reaction (see R12933+R12934)
KEGG:R12933 C01037 + C00011<=>C22458 the first step of two-step reaction (see R03182, R12933+R12934)
KEGG:R12934 C22458 + C00002<=>C01909 + C00008 + C00009 the second step of two-step reaction (see R03182, R12933+R12934)
BioCyc:DETHIOBIOTIN-SYN-RXN CARBON-DIOXIDE + DIAMINONONANOATE + ATP --> 3 PROTON + DETHIOBIOTIN + Pi + ADP The third step in the biosynthesis of biotin.
Rhea:RHEA:15806 (7R,8S)-7,8-diammoniononanoate + CO2 + ATP => (4R,5S)-dethiobiotin + ADP + phosphate + 3 H+ Multi-step reaction: RHEA:63680 and RHEA:63684
Rhea:RHEA:15807 (4R,5S)-dethiobiotin + ADP + phosphate + 3 H+ => (7R,8S)-7,8-diammoniononanoate + CO2 + ATP Multi-step reaction: RHEA:63680 and RHEA:63684
Rhea:RHEA:15808 (7R,8S)-7,8-diammoniononanoate + CO2 + ATP <=> (4R,5S)-dethiobiotin + ADP + phosphate + 3 H+ Multi-step reaction: RHEA:63680 and RHEA:63684