expI, esaI

K22956 expI, esaI; acyl homoserine lactone synthase [EC:2.3.1.184]

Protein Function: acyl homoserine lactone synthase [EC:2.3.1.184]

DBLinks
Proteins
protein id name function taxonomy source
Reactions
reaction id name note
KEGG:R08939 butyryl-[acyl-carrier protein]:S-adenosyl-L-methionine butyryltranserase (lactone-forming, methylthioadenosine-releasing) Butyryl-[acp] + S-Adenosyl-L-methionine <=> Acyl-carrier protein + 5'-Methylthioadenosine + N-Butyryl-L-homoserine lactone
KEGG:R08940 acyl-[acyl-carrier protein]:S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadenosine-releasing) Acyl-[acyl-carrier protein] + S-Adenosyl-L-methionine <=> Acyl-carrier protein + 5'-Methylthioadenosine + N-Acyl-L-homoserine lactone
Rhea:RHEA:10097 a fatty acyl-[ACP] + S-adenosyl-L-methionine => an N-acyl-L-homoserine lactone + S-methyl-5'-thioadenosine + holo-[ACP] + H+
Rhea:RHEA:10098 an N-acyl-L-homoserine lactone + S-methyl-5'-thioadenosine + holo-[ACP] + H+ => a fatty acyl-[ACP] + S-adenosyl-L-methionine
Rhea:RHEA:10099 a fatty acyl-[ACP] + S-adenosyl-L-methionine <=> an N-acyl-L-homoserine lactone + S-methyl-5'-thioadenosine + holo-[ACP] + H+
BioCyc:RXN-10024 S-ADENOSYLMETHIONINE + Butanoyl-ACPs<=>ACP + 5-METHYLTHIOADENOSINE + CPD-10784 + PROTON Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a process known as quorum-sensing. Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggers AHL-signaling which, in turn, initiates the expression of particular virulence genes. N-(3-oxohexanoyl)-[acyl-carrier-protein] and hexanoyl-[acyl-carrier protein] are the best substrates. The fatty-acyl substrate is derived from fatty-acid biosynthesis through acyl-[acyl-carrier-protein] rather than from fatty-acid degradation through acyl-CoA. S-adenosyl-L-methionine cannot be replaced by methionine, S-adenosylhomocysteine, homoserine or homoserine lactone.
BioCyc:RXN-10020 S-ADENOSYLMETHIONINE + 3-Oxo-octanoyl-ACPs<=>ACP + 5-METHYLTHIOADENOSINE + CPD-10782 + PROTON Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a process known as quorum-sensing. Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggers AHL-signaling which, in turn, initiates the expression of particular virulence genes. N-(3-oxohexanoyl)-[acyl-carrier-protein] and hexanoyl-[acyl-carrier protein] are the best substrates. The fatty-acyl substrate is derived from fatty-acid biosynthesis through acyl-[acyl-carrier-protein] rather than from fatty-acid degradation through acyl-CoA. S-adenosyl-L-methionine cannot be replaced by methionine, S-adenosylhomocysteine, homoserine or homoserine lactone.
BioCyc:2.3.1.184-RXN S-ADENOSYLMETHIONINE + ACYL-ACP --> ACP + 5-METHYLTHIOADENOSINE + Acyl-homoserine-lactones + PROTON
BioCyc:RXN-10025 S-ADENOSYLMETHIONINE + Octanoyl-ACPs<=>ACP + 5-METHYLTHIOADENOSINE + CPD-10785 + PROTON Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a process known as quorum-sensing. Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggers AHL-signaling which, in turn, initiates the expression of particular virulence genes. N-(3-oxohexanoyl)-[acyl-carrier-protein] and hexanoyl-[acyl-carrier protein] are the best substrates. The fatty-acyl substrate is derived from fatty-acid biosynthesis through acyl-[acyl-carrier-protein] rather than from fatty-acid degradation through acyl-CoA. S-adenosyl-L-methionine cannot be replaced by methionine, S-adenosylhomocysteine, homoserine or homoserine lactone.
BioCyc:RXN-10022 S-ADENOSYLMETHIONINE + 3-oxo-hexanoyl-ACPs<=>ACP + 5-METHYLTHIOADENOSINE + CPD-10780 + PROTON Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a process known as quorum-sensing. Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggers AHL-signaling which, in turn, initiates the expression of particular virulence genes. N-(3-oxohexanoyl)-[acyl-carrier-protein] and hexanoyl-[acyl-carrier protein] are the best substrates. The fatty-acyl substrate is derived from fatty-acid biosynthesis through acyl-[acyl-carrier-protein] rather than from fatty-acid degradation through acyl-CoA. S-adenosyl-L-methionine cannot be replaced by methionine, S-adenosylhomocysteine, homoserine or homoserine lactone.