数据之源，洞见之始

Protein Function: N-acyl homoserine lactone hydrolase [EC:3.1.1.81]

DBLinks

• KEGG: K13075
• EC Number: 3.1.1.81

Reactions

reaction id	name	note
KEGG:R08970	N-acyl-L-homoserine-lactone lactonohydrolase	N-Acyl-L-homoserine lactone + H2O <=> N-Acyl-L-homoserine
Rhea:RHEA:22577	an N-acyl-L-homoserine lactone + H2O => an N-acyl-L-homoserine + H+
Rhea:RHEA:22578	an N-acyl-L-homoserine + H+ => an N-acyl-L-homoserine lactone + H2O
Rhea:RHEA:22579	an N-acyl-L-homoserine lactone + H2O <=> an N-acyl-L-homoserine + H+
BioCyc:RXN-10050	CPD-10784 + WATER --> PROTON + CPD-10803	Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate theexpression of virulence genes in a process known as quorum-sensing.Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggersAHL-signaling which, in turn, initiates the expression of particular virulence genes.Plants or animals capable of degrading AHLs would have a therapeutic advantage in avoiding bacterial infection asthey could prevent AHL signaling and the expression of virulence genes in quorum-sensing bacteria.N-(3-oxohexanoyl)-L-homoserine lactone, N-(3-oxododecanoyl)-L homoserine lactone, N-butanoyl-L-homoserine lactoneand N-(3-oxooctanoyl)-L-homoserine lactone can act as substrates.
BioCyc:RXN-10047	CPD-10782 + WATER --> PROTON + CPD-10800	Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate theexpression of virulence genes in a process known as quorum-sensing.Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggersAHL-signaling which, in turn, initiates the expression of particular virulence genes.Plants or animals capable of degrading AHLs would have a therapeutic advantage in avoiding bacterial infection asthey could prevent AHL signaling and the expression of virulence genes in quorum-sensing bacteria.N-(3-oxohexanoyl)-L-homoserine lactone, N-(3-oxododecanoyl)-L homoserine lactone, N-butanoyl-L-homoserine lactoneand N-(3-oxooctanoyl)-L-homoserine lactone can act as substrates.
BioCyc:RXN-10051	CPD-10780 + WATER --> PROTON + CPD-10804	Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate theexpression of virulence genes in a process known as quorum-sensing.Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggersAHL-signaling which, in turn, initiates the expression of particular virulence genes.Plants or animals capable of degrading AHLs would have a therapeutic advantage in avoiding bacterial infection asthey could prevent AHL signaling and the expression of virulence genes in quorum-sensing bacteria.N-(3-oxohexanoyl)-L-homoserine lactone, N-(3-oxododecanoyl)-L homoserine lactone, N-butanoyl-L-homoserine lactoneand N-(3-oxooctanoyl)-L-homoserine lactone can act as substrates.
BioCyc:RXN-10048	CPD-10781 + WATER --> PROTON + CPD-10801	Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate theexpression of virulence genes in a process known as quorum-sensing.Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggersAHL-signaling which, in turn, initiates the expression of particular virulence genes.Plants or animals capable of degrading AHLs would have a therapeutic advantage in avoiding bacterial infection asthey could prevent AHL signaling and the expression of virulence genes in quorum-sensing bacteria.N-(3-oxohexanoyl)-L-homoserine lactone, N-(3-oxododecanoyl)-L homoserine lactone, N-butanoyl-L-homoserine lactoneand N-(3-oxooctanoyl)-L-homoserine lactone can act as substrates.
BioCyc:3.1.1.81-RXN	Acyl-homoserine-lactones + WATER --> Acyl-homoserines + PROTON
BioCyc:RXN-10052	CPD-10785 + WATER --> PROTON + CPD-10805	Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate theexpression of virulence genes in a process known as quorum-sensing.Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggersAHL-signaling which, in turn, initiates the expression of particular virulence genes.Plants or animals capable of degrading AHLs would have a therapeutic advantage in avoiding bacterial infection asthey could prevent AHL signaling and the expression of virulence genes in quorum-sensing bacteria.N-(3-oxohexanoyl)-L-homoserine lactone, N-(3-oxododecanoyl)-L homoserine lactone, N-butanoyl-L-homoserine lactoneand N-(3-oxooctanoyl)-L-homoserine lactone can act as substrates.