数据之源，洞见之始

BioCyc:RXN-10052

Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate theexpression of virulence genes in a process known as quorum-sensing.Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggersAHL-signaling which, in turn, initiates the expression of particular virulence genes.Plants or animals capable of degrading AHLs would have a therapeutic advantage in avoiding bacterial infection asthey could prevent AHL signaling and the expression of virulence genes in quorum-sensing bacteria.N-(3-oxohexanoyl)-L-homoserine lactone, N-(3-oxododecanoyl)-L homoserine lactone, N-butanoyl-L-homoserine lactoneand N-(3-oxooctanoyl)-L-homoserine lactone can act as substrates.