ASRGL1, iaaA

K13051 ASRGL1, iaaA; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]

Protein Function: L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]

DBLinks
Proteins
protein id name function taxonomy source
Reactions
reaction id name note
BioCyc:RXN0-3241 CPD-12991 + WATER --> L-ASPARTATE + Amino-Acids-20 This reaction is the hydrolysis of a β peptide bond formed between the side-chain carboxyl group of an aspartateresidue and some other amino acid. This reaction has maximum activity for cleavage of an aspartyl-leucine dipeptide.Relative activity for hydrolysis of other dipeptides is lower: aspartyl-serine (82%), aspartyl-methionine (68%),aspartyl-valine (56%), aspartyl-glutamate (48%), aspartyl-phenylalanine (38%), aspartyl-alanine (33%),aspartyl-isoleucine (19%), aspartyl-threonine (18%). This reaction has no activity for cleavage of aspartyl-glycine,aspartyl-histidine, or tripeptides.
BioCyc:3.4.19.5-RXN Beta-Aspartyl-Peptides + WATER --> L-ASPARTATE + Peptide-Holder-Alternative
BioCyc:RXN-21711 CPD-14415 + WATER --> L-ASPARTATE + ARG
KEGG:R00485 L-asparagine amidohydrolase L-Asparagine + H2O <=> L-Aspartate + Ammonia
KEGG:R06134 C00241 + C00001<=>C00060 + C00014 general reaction
BioCyc:ASPARAGHYD-RXN ASN + WATER --> L-ASPARTATE + AMMONIUM
Rhea:RHEA:21017 L-asparagine + H2O => L-aspartate + NH4+ RHEA:21016 part of RHEA:11188 Published in: Yanase, H., Sakai, T., Tonomuro, K. (1983). "Purification, crystallization and some properties of beta-cyano-L-alanine-degrading enzyme in Pseudomonas sp. 13." Agric. Biol. Chem. 47:473-482. DOI:10.1271/bbb1961.47.473
Rhea:RHEA:21018 L-aspartate + NH4+ => L-asparagine + H2O RHEA:21016 part of RHEA:11188 Published in: Yanase, H., Sakai, T., Tonomuro, K. (1983). "Purification, crystallization and some properties of beta-cyano-L-alanine-degrading enzyme in Pseudomonas sp. 13." Agric. Biol. Chem. 47:473-482. DOI:10.1271/bbb1961.47.473
Rhea:RHEA:21019 L-asparagine + H2O <=> L-aspartate + NH4+ RHEA:21016 part of RHEA:11188 Published in: Yanase, H., Sakai, T., Tonomuro, K. (1983). "Purification, crystallization and some properties of beta-cyano-L-alanine-degrading enzyme in Pseudomonas sp. 13." Agric. Biol. Chem. 47:473-482. DOI:10.1271/bbb1961.47.473