Pathways Knowlegdes

Necessitatibus eius consequatur ex aliquid fuga eum quidem sint consectetur velit

Pathway DOIs Note
Metabolism

Accession ID: Reactome:R-BTA-1430728		 -
Metabolism

Accession ID: Reactome:R-CFA-1430728		 -
Phase II - Conjugation of compounds

Accession ID: Reactome:R-CFA-156580
  • 10.1124/jpet.300.2.361
 McCarver DG, Hines RN. The Ontogeny of Human Drug-Metabolizing Enzymes: Phase II Conjugation Enzymes and Regulatory Mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 2002 Feb;300(2):361–6. doi: 10.1124/jpet.300.2.361.
Cytosolic sulfonation of small molecules

Accession ID: Reactome:R-DRE-156584
  • 10.1016/s0009-2797(00)00202-7
  • 10.1016/s0304-3835(99)00136-6
  • 10.1093/toxsci/kfj061
  • 10.1096/fasebj.11.1.9034160
  • 10.1097/00008571-200403000-00009
  • 10.1210/er.2001-0040
 Gamage N, Barnett A, Hempel N, Duggleby RG, Windmill KF, Martin JL, McManus ME. Human sulfotransferases and their role in chemical metabolism. Toxicol Sci. 2006 Mar;90(1):5–22. doi: 10.1093/toxsci/kfj061. PMID: 16322073.; Blanchard RL, Freimuth RR, Buck J, Weinshilboum RM, Coughtrie MW. A proposed nomenclature system for the cytosolic sulfotransferase (SULT) superfamily. Pharmacogenetics. 2004 Mar;14(3):199–211. doi: 10.1097/00008571-200403000-00009. PMID: 15167709.; Strott CA. Sulfonation and molecular action. Endocr Rev. 2002 Oct;23(5):703–32. doi: 10.1210/er.2001-0040. PMID: 12372849.; Glatt H. Sulfotransferases in the bioactivation of xenobiotics. Chem Biol Interact. 2000 Dec 01;129(1-2):141–70. doi: 10.1016/s0009-2797(00)00202-7. PMID: 11154739.; Yamazoe Y, Nagata K, Yoshinari K, Fujita K, Shiraga T, Iwasaki K. Sulfotransferase catalyzing sulfation of heterocyclic amines. Cancer Lett. 1999 Sep 01;143(2):103–7. doi: 10.1016/s0304-3835(99)00136-6. PMID: 10503886.; Weinshilboum RM, Otterness DM, Aksoy IA, Wood TC, Her C, Raftogianis RB. Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes. FASEB J. 1997 Jan;11(1):3–14. PMID: 9034160.
Phase II - Conjugation of compounds

Accession ID: Reactome:R-GGA-156580
  • 10.1124/jpet.300.2.361
 McCarver DG, Hines RN. The Ontogeny of Human Drug-Metabolizing Enzymes: Phase II Conjugation Enzymes and Regulatory Mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 2002 Feb;300(2):361–6. doi: 10.1124/jpet.300.2.361.
Biological oxidations

Accession ID: Reactome:R-HSA-211859		 -
Metabolism

Accession ID: Reactome:R-MMU-1430728		 -
Biological oxidations

Accession ID: Reactome:R-MMU-211859		 -
Cytosolic sulfonation of small molecules

Accession ID: Reactome:R-XTR-156584
  • 10.1016/s0009-2797(00)00202-7
  • 10.1016/s0304-3835(99)00136-6
  • 10.1093/toxsci/kfj061
  • 10.1096/fasebj.11.1.9034160
  • 10.1097/00008571-200403000-00009
  • 10.1210/er.2001-0040
 Gamage N, Barnett A, Hempel N, Duggleby RG, Windmill KF, Martin JL, McManus ME. Human sulfotransferases and their role in chemical metabolism. Toxicol Sci. 2006 Mar;90(1):5–22. doi: 10.1093/toxsci/kfj061. PMID: 16322073.; Blanchard RL, Freimuth RR, Buck J, Weinshilboum RM, Coughtrie MW. A proposed nomenclature system for the cytosolic sulfotransferase (SULT) superfamily. Pharmacogenetics. 2004 Mar;14(3):199–211. doi: 10.1097/00008571-200403000-00009. PMID: 15167709.; Strott CA. Sulfonation and molecular action. Endocr Rev. 2002 Oct;23(5):703–32. doi: 10.1210/er.2001-0040. PMID: 12372849.; Glatt H. Sulfotransferases in the bioactivation of xenobiotics. Chem Biol Interact. 2000 Dec 01;129(1-2):141–70. doi: 10.1016/s0009-2797(00)00202-7. PMID: 11154739.; Yamazoe Y, Nagata K, Yoshinari K, Fujita K, Shiraga T, Iwasaki K. Sulfotransferase catalyzing sulfation of heterocyclic amines. Cancer Lett. 1999 Sep 01;143(2):103–7. doi: 10.1016/s0304-3835(99)00136-6. PMID: 10503886.; Weinshilboum RM, Otterness DM, Aksoy IA, Wood TC, Her C, Raftogianis RB. Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes. FASEB J. 1997 Jan;11(1):3–14. PMID: 9034160.
Biological oxidations

Accession ID: Reactome:R-BTA-211859		 -
Cytosolic sulfonation of small molecules

Accession ID: Reactome:R-CFA-156584
  • 10.1016/s0009-2797(00)00202-7
  • 10.1016/s0304-3835(99)00136-6
  • 10.1093/toxsci/kfj061
  • 10.1096/fasebj.11.1.9034160
  • 10.1097/00008571-200403000-00009
  • 10.1210/er.2001-0040
 Gamage N, Barnett A, Hempel N, Duggleby RG, Windmill KF, Martin JL, McManus ME. Human sulfotransferases and their role in chemical metabolism. Toxicol Sci. 2006 Mar;90(1):5–22. doi: 10.1093/toxsci/kfj061. PMID: 16322073.; Blanchard RL, Freimuth RR, Buck J, Weinshilboum RM, Coughtrie MW. A proposed nomenclature system for the cytosolic sulfotransferase (SULT) superfamily. Pharmacogenetics. 2004 Mar;14(3):199–211. doi: 10.1097/00008571-200403000-00009. PMID: 15167709.; Strott CA. Sulfonation and molecular action. Endocr Rev. 2002 Oct;23(5):703–32. doi: 10.1210/er.2001-0040. PMID: 12372849.; Glatt H. Sulfotransferases in the bioactivation of xenobiotics. Chem Biol Interact. 2000 Dec 01;129(1-2):141–70. doi: 10.1016/s0009-2797(00)00202-7. PMID: 11154739.; Yamazoe Y, Nagata K, Yoshinari K, Fujita K, Shiraga T, Iwasaki K. Sulfotransferase catalyzing sulfation of heterocyclic amines. Cancer Lett. 1999 Sep 01;143(2):103–7. doi: 10.1016/s0304-3835(99)00136-6. PMID: 10503886.; Weinshilboum RM, Otterness DM, Aksoy IA, Wood TC, Her C, Raftogianis RB. Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes. FASEB J. 1997 Jan;11(1):3–14. PMID: 9034160.
Cytosolic sulfonation of small molecules

Accession ID: Reactome:R-GGA-156584
  • 10.1016/s0009-2797(00)00202-7
  • 10.1016/s0304-3835(99)00136-6
  • 10.1093/toxsci/kfj061
  • 10.1096/fasebj.11.1.9034160
  • 10.1097/00008571-200403000-00009
  • 10.1210/er.2001-0040
 Gamage N, Barnett A, Hempel N, Duggleby RG, Windmill KF, Martin JL, McManus ME. Human sulfotransferases and their role in chemical metabolism. Toxicol Sci. 2006 Mar;90(1):5–22. doi: 10.1093/toxsci/kfj061. PMID: 16322073.; Blanchard RL, Freimuth RR, Buck J, Weinshilboum RM, Coughtrie MW. A proposed nomenclature system for the cytosolic sulfotransferase (SULT) superfamily. Pharmacogenetics. 2004 Mar;14(3):199–211. doi: 10.1097/00008571-200403000-00009. PMID: 15167709.; Strott CA. Sulfonation and molecular action. Endocr Rev. 2002 Oct;23(5):703–32. doi: 10.1210/er.2001-0040. PMID: 12372849.; Glatt H. Sulfotransferases in the bioactivation of xenobiotics. Chem Biol Interact. 2000 Dec 01;129(1-2):141–70. doi: 10.1016/s0009-2797(00)00202-7. PMID: 11154739.; Yamazoe Y, Nagata K, Yoshinari K, Fujita K, Shiraga T, Iwasaki K. Sulfotransferase catalyzing sulfation of heterocyclic amines. Cancer Lett. 1999 Sep 01;143(2):103–7. doi: 10.1016/s0304-3835(99)00136-6. PMID: 10503886.; Weinshilboum RM, Otterness DM, Aksoy IA, Wood TC, Her C, Raftogianis RB. Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes. FASEB J. 1997 Jan;11(1):3–14. PMID: 9034160.
Phase II - Conjugation of compounds

Accession ID: Reactome:R-HSA-156580
  • 10.1124/jpet.300.2.361
 McCarver DG, Hines RN. The Ontogeny of Human Drug-Metabolizing Enzymes: Phase II Conjugation Enzymes and Regulatory Mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 2002 Feb;300(2):361–6. doi: 10.1124/jpet.300.2.361.
Phase II - Conjugation of compounds

Accession ID: Reactome:R-MMU-156580
  • 10.1124/jpet.300.2.361
 McCarver DG, Hines RN. The Ontogeny of Human Drug-Metabolizing Enzymes: Phase II Conjugation Enzymes and Regulatory Mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 2002 Feb;300(2):361–6. doi: 10.1124/jpet.300.2.361.
Biological oxidations

Accession ID: Reactome:R-RNO-211859		 -
Metabolism

Accession ID: Reactome:R-SSC-1430728		 -
Biological oxidations

Accession ID: Reactome:R-SSC-211859		 -
Cytosolic sulfonation of small molecules

Accession ID: Reactome:R-BTA-156584
  • 10.1016/s0009-2797(00)00202-7
  • 10.1016/s0304-3835(99)00136-6
  • 10.1093/toxsci/kfj061
  • 10.1096/fasebj.11.1.9034160
  • 10.1097/00008571-200403000-00009
  • 10.1210/er.2001-0040
 Gamage N, Barnett A, Hempel N, Duggleby RG, Windmill KF, Martin JL, McManus ME. Human sulfotransferases and their role in chemical metabolism. Toxicol Sci. 2006 Mar;90(1):5–22. doi: 10.1093/toxsci/kfj061. PMID: 16322073.; Blanchard RL, Freimuth RR, Buck J, Weinshilboum RM, Coughtrie MW. A proposed nomenclature system for the cytosolic sulfotransferase (SULT) superfamily. Pharmacogenetics. 2004 Mar;14(3):199–211. doi: 10.1097/00008571-200403000-00009. PMID: 15167709.; Strott CA. Sulfonation and molecular action. Endocr Rev. 2002 Oct;23(5):703–32. doi: 10.1210/er.2001-0040. PMID: 12372849.; Glatt H. Sulfotransferases in the bioactivation of xenobiotics. Chem Biol Interact. 2000 Dec 01;129(1-2):141–70. doi: 10.1016/s0009-2797(00)00202-7. PMID: 11154739.; Yamazoe Y, Nagata K, Yoshinari K, Fujita K, Shiraga T, Iwasaki K. Sulfotransferase catalyzing sulfation of heterocyclic amines. Cancer Lett. 1999 Sep 01;143(2):103–7. doi: 10.1016/s0304-3835(99)00136-6. PMID: 10503886.; Weinshilboum RM, Otterness DM, Aksoy IA, Wood TC, Her C, Raftogianis RB. Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes. FASEB J. 1997 Jan;11(1):3–14. PMID: 9034160.
Biological oxidations

Accession ID: Reactome:R-CFA-211859		 -
Metabolism

Accession ID: Reactome:R-DRE-1430728		 -