Pathways Knowlegdes

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Pathway DOIs Note
sulfite oxidation IV

Accession ID: BioCyc:BSUB_PWY-5326
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sulfate reduction I (assimilatory)

Accession ID: BioCyc:SYNEL_SO4ASSIM-PWY
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sulfate reduction I (assimilatory)

Accession ID: BioCyc:ECOL316407_SO4ASSIM-PWY
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superpathway of sulfate assimilation and cysteine biosynthesis

Accession ID: BioCyc:ECOL316407_SULFATE-CYS-PWY
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superpathway of sulfate assimilation and cysteine biosynthesis

Accession ID: BioCyc:ECOL413997_SULFATE-CYS-PWY
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sulfate reduction I (assimilatory)

Accession ID: BioCyc:MOB3B_SO4ASSIM-PWY
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superpathway of sulfate assimilation and cysteine biosynthesis

Accession ID: BioCyc:CLOSSAC_SULFATE-CYS-PWY
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chondroitin sulfate and dermatan sulfate degradation I (bacterial)

Accession ID: BioCyc:CLOSSAC_PWY-6572
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superpathway of sulfate assimilation and cysteine biosynthesis

Accession ID: BioCyc:BTHE_SULFATE-CYS-PWY
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superpathway of methionine biosynthesis (by sulfhydrylation)

Accession ID: BioCyc:BTHE_PWY-5345
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thiosulfate oxidation IV (multienzyme complex)

Accession ID: BioCyc:META_PWY-6677
  • 10.1016/j.febslet.2009.03.020
  • 10.1111/j.1365-2958.2006.05408.x
Welte C, Hafner S, Krätzer C, Quentmeier A, Friedrich CG, Dahl C. Interaction between Sox proteins of two physiologically distinct bacteria and a new protein involved in thiosulfate oxidation. FEBS Lett. 2009 Apr 17;583(8):1281–6. doi: 10.1016/j.febslet.2009.03.020. PMID: 19303410.; Hensen D, Sperling D, Trüper HG, Brune DC, Dahl C. Thiosulphate oxidation in the phototrophic sulphur bacterium Allochromatium vinosum. Molecular Microbiology. 2006 Sep 25;62(3):794–810. doi: 10.1111/j.1365-2958.2006.05408.x.
thiosulfate oxidation III (multienzyme complex)

Accession ID: BioCyc:META_PWY-5296
  • 10.1023/a:1000135707181
  • 10.1128/aem.67.7.2873-2882.2001
  • 10.1371/journal.pone.0173395
Grabarczyk DB, Berks BC. Intermediates in the Sox sulfur oxidation pathway are bound to a sulfane conjugate of the carrier protein SoxYZ. PLoS ONE. 2017 Mar 03;12(3):e0173395. doi: 10.1371/journal.pone.0173395.; Friedrich CG, Rother D, Bardischewsky F, Quentmeier A, Fischer J. Oxidation of Reduced Inorganic Sulfur Compounds by Bacteria: Emergence of a Common Mechanism? Appl Environ Microbiol. 2001 Jul;67(7):2873–82. doi: 10.1128/aem.67.7.2873-2882.2001.; Kelly DP, Shergill JK, Lu WP, Wood AP. Oxidative metabolism of inorganic sulfur compounds by bacteria. Antonie Van Leeuwenhoek. 1997 Feb;71(1-2):95–107. doi: 10.1023/a:1000135707181. PMID: 9049021.
molybdenum cofactor biosynthesis

Accession ID: BioCyc:META_PWY-6823
  • 10.1016/s0021-9258(19)38677-6
  • 10.1146/annurev.arplant.57.032905.105437
Schwarz G, Mendel RR. Molybdenum cofactor biosynthesis and molybdenum enzymes. Annu Rev Plant Biol. 2006;57():623–47. doi: 10.1146/annurev.arplant.57.032905.105437. PMID: 16669776.; Pitterle DM, Rajagopalan KV. The biosynthesis of molybdopterin in Escherichia coli. Purification and characterization of the converting factor. Journal of Biological Chemistry. 1993 Jun;268(18):13499–505. doi: 10.1016/s0021-9258(19)38677-6.
sulfate activation for sulfonation

Accession ID: BioCyc:META_PWY-5340
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heparin degradation

Accession ID: BioCyc:META_PWY-7644
  • 10.1016/s0021-9258(19)43461-3
  • 10.1128/aem.62.8.2723-2734.1996
Su H, Blain F, Musil RA, Zimmermann JJ, Gu K, Bennett DC. Isolation and expression in Escherichia coli of hepB and hepC, genes coding for the glycosaminoglycan-degrading enzymes heparinase II and heparinase III, respectively, from Flavobacterium heparinum. Appl Environ Microbiol. 1996 Aug;62(8):2723–34. doi: 10.1128/aem.62.8.2723-2734.1996.; Dietrich CP, Silva ME, Michelacci YM. Sequential degradation of heparin in Flavobacterium heparinum. Purification and properties of five enzymes involved in heparin degradation. J Biol Chem. 1973 Sep 25;248(18):6408–15. PMID: 4730325.
κ-carrageenan degradation

Accession ID: BioCyc:META_PWY-6821
  • 10.1111/j.1432-1033.1981.tb05084.x
McLEAN MW, WILLIAMSON FB. Neocarratetraose 4-O-Monosulphate ß-Hydrolase from Pseudomonas carrageenovora. European Journal of Biochemistry. 1981 Jan;113(3):447–56. doi: 10.1111/j.1432-1033.1981.tb05084.x.
sulfide oxidation IV (metazoa)

Accession ID: BioCyc:META_PWY-7927
  • 10.1074/jbc.m114.602664
  • 10.1111/j.1742-4658.2008.06482.x
Libiad M, Yadav PK, Vitvitsky V, Martinov M, Banerjee R. Organization of the Human Mitochondrial Hydrogen Sulfide Oxidation Pathway. Journal of Biological Chemistry. 2014 Nov;289(45):30901–10. doi: 10.1074/jbc.m114.602664.; Hildebrandt TM, Grieshaber MK. Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. FEBS J. 2008 Jul;275(13):3352–61. doi: 10.1111/j.1742-4658.2008.06482.x. PMID: 18494801.
superpathway of hexitol degradation (bacteria)

Accession ID: BioCyc:META_HEXITOLDEGSUPER-PWY
  • 10.1017/s0031182097001121
  • 10.1128/jb.159.3.986-990.1984
SCHMATZ DM. The mannitol cycle in Eimeria. Parasitology. 1997 Jun;114(7):81–9. doi: 10.1017/s0031182097001121.; Novotny MJ, Reizer J, Esch F, Saier MH. Purification and properties of D-mannitol-1-phosphate dehydrogenase and D-glucitol-6-phosphate dehydrogenase from Escherichia coli. J Bacteriol. 1984 Sep;159(3):986–90. doi: 10.1128/jb.159.3.986-990.1984.
superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae)

Accession ID: BioCyc:META_PWY-821
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superpathway of sulfur oxidation (Acidianus ambivalens)

Accession ID: BioCyc:META_PWY-5304
  • 10.1007/s002030050743
  • 10.1074/jbc.m114.591669
  • 10.1099/mic.0.26455-0
  • 10.1111/j.1365-2958.2004.04193.x
  • 10.1128/jb.171.3.1638-1643.1989
Liu L, Stockdreher Y, Koch T, Sun S, Fan Z, Josten M, Sahl H, Wang Q, Luo Y, Liu S, Dahl C, Jiang C. Thiosulfate Transfer Mediated by DsrE/TusA Homologs from Acidothermophilic Sulfur-oxidizing Archaeon Metallosphaera cuprina. Journal of Biological Chemistry. 2014 Sep;289(39):26949–59. doi: 10.1074/jbc.m114.591669.; Müller FH, Bandeiras TM, Urich T, Teixeira M, Gomes CM, Kletzin A. Coupling of the pathway of sulphur oxidation to dioxygen reduction: characterization of a novel membrane-bound thiosulphate:quinone oxidoreductase. Mol Microbiol. 2004 Aug;53(4):1147–60. doi: 10.1111/j.1365-2958.2004.04193.x. PMID: 15306018.; Laska S, Lottspeich F, Kletzin A. Membrane-bound hydrogenase and sulfur reductase of the hyperthermophilic and acidophilic archaeon Acidianus ambivalens. Microbiology (Reading). 2003 Sep;149(Pt 9):2357–71. doi: 10.1099/mic.0.26455-0. PMID: 12949162.; Zimmermann P, Laska S, Kletzin A. Two modes of sulfite oxidation in the extremely thermophilic and acidophilic archaeon Acidianus ambivalens. Archives of Microbiology. 1999 Jul 26;172(2):76–82. doi: 10.1007/s002030050743.; Kletzin A. Coupled enzymatic production of sulfite, thiosulfate, and hydrogen sulfide from sulfur: purification and properties of a sulfur oxygenase reductase from the facultatively anaerobic archaebacterium Desulfurolobus ambivalens. J Bacteriol. 1989 Mar;171(3):1638–43. doi: 10.1128/jb.171.3.1638-1643.1989.