Pathways Knowlegdes
Necessitatibus eius consequatur ex aliquid fuga eum quidem sint consectetur velit
| Pathway | DOIs | Note |
|---|---|---|
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-GGA-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-DDI-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-CEL-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-SSC-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-RNO-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-CFA-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-DME-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-MMU-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-HSA-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-XTR-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Events associated with phagocytolytic activity of PMN cells Accession ID: Reactome:R-BTA-8941413 |
|
Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Winterbourn CC, Kettle AJ. Redox reactions and microbial killing in the neutrophil phagosome. Antioxid Redox Signal. 2013 Feb 20;18(6):642–60. doi: 10.1089/ars.2012.4827. PMID: 22881869.; Demaurex N, El Chemaly A. Physiological roles of voltage-gated proton channels in leukocytes. J Physiol. 2010 Dec 01;588(Pt 23):4659–65. PMID: 20693294; PMCID: PMC3010135.; Petheo GL, Orient A, Baráth M, Kovács I, Réthi B, Lányi Á, Rajki A, Rajnavölgyi É, Geiszt M. Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes. PLoS ONE. 2010 Nov 23;5(11):e14081. doi: 10.1371/journal.pone.0014081.; El Chemaly A, Okochi Y, Sasaki M, Arnaudeau S, Okamura Y, Demaurex N. VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification. J Exp Med. 2010 Jan 18;207(1):129–39. PMID: 20026664; PMCID: PMC2812533.; Henderson LM, Chappell JB, Jones OT. Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge. Biochem J. 1988 Oct 01;255(1):285–90. PMID: 2848506; PMCID: PMC1135221.; Henderson LM, Chappell JB, Jones OT. The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel. Biochem J. 1987 Sep 01;246(2):325–9. PMID: 2825632; PMCID: PMC1148280. |
| Immune System Accession ID: Reactome:R-BTA-168256 |
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| Immune System Accession ID: Reactome:R-DDI-168256 |
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| ROS and RNS production in phagocytes Accession ID: Reactome:R-DDI-1222556 |
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Erard M, Dupré-Crochet S, Nüße O. Biosensors for spatiotemporal detection of reactive oxygen species in cells and tissues. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2018 May 01;314(5):R667–83. doi: 10.1152/ajpregu.00140.2017.; Winterbourn CC, Kettle AJ, Hampton MB. Reactive Oxygen Species and Neutrophil Function. Annu Rev Biochem. 2016 Jun 02;85():765–92. doi: 10.1146/annurev-biochem-060815-014442. PMID: 27050287.; Levine AP, Duchen MR, de Villiers S, Rich PR, Segal AW. Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity. PLoS ONE. 2015 Apr 17;10(4):e0125906. doi: 10.1371/journal.pone.0125906.; Weidinger A, Kozlov AV. Biological Activities of Reactive Oxygen and Nitrogen Species: Oxidative Stress versus Signal Transduction. Biomolecules. 2015 Apr 15;5(2):472–84. 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| Immune System Accession ID: Reactome:R-DME-168256 |
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| Immune System Accession ID: Reactome:R-MMU-168256 |
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| Innate Immune System Accession ID: Reactome:R-MMU-168249 |
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| Immune System Accession ID: Reactome:R-SSC-168256 |
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| Innate Immune System Accession ID: Reactome:R-XTR-168249 |
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| Innate Immune System Accession ID: Reactome:R-BTA-168249 |
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