Pathways Knowlegdes

Necessitatibus eius consequatur ex aliquid fuga eum quidem sint consectetur velit

Pathway DOIs Note
acetone degradation I (to methylglyoxal)

Accession ID: BioCyc:META_PWY-5451
  • 10.1016/s0021-9258(17)38768-9
  • 10.1016/s0021-9258(17)43646-5
 Koop DR, Casazza JP. Identification of ethanol-inducible P-450 isozyme 3a as the acetone and acetol monooxygenase of rabbit microsomes. Journal of Biological Chemistry. 1985 Nov;260(25):13607–12. doi: 10.1016/s0021-9258(17)38768-9.; Casazza JP, Felver ME, Veech RL. The metabolism of acetone in rat. Journal of Biological Chemistry. 1984 Jan;259(1):231–6. doi: 10.1016/s0021-9258(17)43646-5.
superpathway of methylglyoxal degradation

Accession ID: BioCyc:META_METHGLYUT-PWY
  • 10.1074/mcp.d500006-mcp200
 Lopez-Campistrous A, Semchuk P, Burke L, Palmer-Stone T, Brokx SJ, Broderick G, Bottorff D, Bolch S, Weiner JH, Ellison MJ. Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol Cell Proteomics. 2005 Aug;4(8):1205–9. doi: 10.1074/mcp.d500006-mcp200. PMID: 15911532.
12-epi-fischerindole biosynthesis

Accession ID: BioCyc:META_PWY-7958
  • 10.1002/anie.200501941
  • 10.1002/anie.200501942
  • 10.1021/acs.orglett.7b00258
  • 10.1021/cb400681n
  • 10.1021/jacs.5b10136
  • 10.1038/nchembio.2327
 Li S, Lowell AN, Newmister SA, Yu F, Williams RM, Sherman DH. Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids. Nature Chemical Biology. 2017 Mar 13;13(5):467–9. doi: 10.1038/nchembio.2327.; Chang WC, Sanyal D, Huang JL, Ittiamornkul K, Zhu Q, Liu X. In Vitro Stepwise Reconstitution of Amino Acid Derived Vinyl Isocyanide Biosynthesis: Detection of an Elusive Intermediate. Org Lett. 2017 Mar 03;19(5):1208–11. doi: 10.1021/acs.orglett.7b00258. PMID: 28212039.; Li S, Lowell AN, Yu F, Raveh A, Newmister SA, Bair N, Schaub JM, Williams RM, Sherman DH. Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C–C Bond-Forming Cascade. J. Am. Chem. Soc. 2015 Dec 02;137(49):15366–9. doi: 10.1021/jacs.5b10136.; Hillwig ML, Zhu Q, Liu X. Biosynthesis of Ambiguine Indole Alkaloids in CyanobacteriumFischerella ambigua. ACS Chem. Biol. 2013 Nov 20;9(2):372–7. doi: 10.1021/cb400681n.; Brady SF, Clardy J. Systematic investigation of the Escherichia coli metabolome for the biosynthetic origin of an isocyanide carbon atom. Angew Chem Int Ed Engl. 2005 Nov 04;44(43):7045–8. doi: 10.1002/anie.200501942. PMID: 16217820.; Brady SF, Clardy J. Cloning and heterologous expression of isocyanide biosynthetic genes from environmental DNA. Angew Chem Int Ed Engl. 2005 Nov 04;44(43):7063–5. doi: 10.1002/anie.200501941. PMID: 16206308.
3-[(E)-2-isocyanoethenyl]-1H-indole biosynthesis

Accession ID: BioCyc:META_PWY-7956
  • 10.1002/anie.200501941
  • 10.1002/anie.200501942
  • 10.1021/acs.orglett.7b00258
 Chang WC, Sanyal D, Huang JL, Ittiamornkul K, Zhu Q, Liu X. In Vitro Stepwise Reconstitution of Amino Acid Derived Vinyl Isocyanide Biosynthesis: Detection of an Elusive Intermediate. Org Lett. 2017 Mar 03;19(5):1208–11. doi: 10.1021/acs.orglett.7b00258. PMID: 28212039.; Brady SF, Clardy J. Cloning and heterologous expression of isocyanide biosynthetic genes from environmental DNA. Angew Chem Int Ed Engl. 2005 Nov 04;44(43):7063–5. doi: 10.1002/anie.200501941. PMID: 16206308.; Brady SF, Clardy J. Systematic investigation of the Escherichia coli metabolome for the biosynthetic origin of an isocyanide carbon atom. Angew Chem Int Ed Engl. 2005 Nov 04;44(43):7045–8. doi: 10.1002/anie.200501942. PMID: 16217820.
methylglyoxal degradation III

Accession ID: BioCyc:ARA_PWY-5453		 -
methylglyoxal degradation III

Accession ID: BioCyc:SYNEL_PWY-5453		 -
methylglyoxal degradation III

Accession ID: BioCyc:ECOL316407_PWY-5453		 -
superpathway of methylglyoxal degradation

Accession ID: BioCyc:ECOL413997_METHGLYUT-PWY		 -
Methylglyoxal Degradation III

Accession ID: PathBank:SMP0002091		 -
detoxification of reactive carbonyls in chloroplasts

Accession ID: PlantCyc:ARA_PWY-6786
  • 10.1016/j.jmb.2009.07.023
  • 10.1074/jbc.m110.202226
 Yamauchi Y, Hasegawa A, Taninaka A, Mizutani M, Sugimoto Y. NADPH-dependent Reductases Involved in the Detoxification of Reactive Carbonyls in Plants. Journal of Biological Chemistry. 2011 Mar;286(9):6999–7009. doi: 10.1074/jbc.m110.202226.; Simpson PJ, Tantitadapitak C, Reed AM, Mather OC, Bunce CM, White SA, Ride JP. Characterization of two novel aldo-keto reductases from Arabidopsis: expression patterns, broad substrate specificity, and an open active-site structure suggest a role in toxicant metabolism following stress. J Mol Biol. 2009 Sep 18;392(2):465–80. doi: 10.1016/j.jmb.2009.07.023. PMID: 19616008.
detoxification of reactive carbonyls in chloroplasts

Accession ID: PlantCyc:WHEATA_PWY-6786		 -
detoxification of reactive carbonyls in chloroplasts

Accession ID: PlantCyc:WHEATD_PWY-6786		 -
detoxification of reactive carbonyls in chloroplasts

Accession ID: PlantCyc:CACUMINATA_PWY-6786		 -
methylglyoxal degradation III

Accession ID: PlantCyc:CANNUUM_PWY-5453		 -
methylglyoxal degradation III

Accession ID: PlantCyc:PPERSICA_PWY-5453		 -
detoxification of reactive carbonyls in chloroplasts

Accession ID: PlantCyc:CCAPSULARIS_PWY-6786		 -
detoxification of reactive carbonyls in chloroplasts

Accession ID: PlantCyc:CHINESECABBAGE_PWY-6786		 -
detoxification of reactive carbonyls in chloroplasts

Accession ID: PlantCyc:SPIDERFLOWER_PWY-6786		 -
detoxification of reactive carbonyls in chloroplasts

Accession ID: PlantCyc:CLEMENTINE_PWY-6786		 -
methylglyoxal degradation III

Accession ID: PlantCyc:SPIRODELA_PWY-5453		 -