Pathways Knowlegdes

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Pathway DOIs Note
L-carnitine biosynthesis

Accession ID: BioCyc:META_PWY-6100
  • 10.1016/j.ab.2006.04.007
  • 10.1016/j.mam.2004.06.006
  • 10.1016/s0021-9258(17)34915-3
  • 10.1016/s0021-9258(17)40983-5
  • 10.1042/0264-6021:3610417
 van Vlies N, Wanders RJ, Vaz FM. Measurement of carnitine biosynthesis enzyme activities by tandem mass spectrometry: differences between the mouse and the rat. Anal Biochem. 2006 Jul 01;354(1):132–9. doi: 10.1016/j.ab.2006.04.007. PMID: 16707092.; Steiber A, Kerner J, Hoppel CL. Carnitine: a nutritional, biosynthetic, and functional perspective. Mol Aspects Med. 2004 Oct;25(5-6):455–73. doi: 10.1016/j.mam.2004.06.006. PMID: 15363636.; Vaz FM, Wanders RJ. Carnitine biosynthesis in mammals. Biochem J. 2002 Feb 01;361(Pt 3):417–29. PMID: 11802770; PMCID: PMC1222323.; Hulse JD, Ellis SR, Henderson LM. Carnitine biosynthesis. beta-Hydroxylation of trimethyllysine by an alpha-ketoglutarate-dependent mitochondrial dioxygenase. Journal of Biological Chemistry. 1978 Mar;253(5):1654–9. doi: 10.1016/s0021-9258(17)34915-3.; Kaufman RA, Broquist HP. Biosynthesis of carnitine in Neurospora crassa. Journal of Biological Chemistry. 1977 Nov;252(21):7437–9. doi: 10.1016/s0021-9258(17)40983-5.
L-carnitine biosynthesis

Accession ID: BioCyc:HUMAN_PWY-6100
  • 10.1016/j.ab.2006.04.007
  • 10.1016/j.mam.2004.06.006
  • 10.1016/s0021-9258(17)34915-3
  • 10.1016/s0021-9258(17)40983-5
  • 10.1042/0264-6021:3610417
 van Vlies N, Wanders RJ, Vaz FM. Measurement of carnitine biosynthesis enzyme activities by tandem mass spectrometry: differences between the mouse and the rat. Anal Biochem. 2006 Jul 01;354(1):132–9. doi: 10.1016/j.ab.2006.04.007. PMID: 16707092.; Steiber A, Kerner J, Hoppel CL. Carnitine: a nutritional, biosynthetic, and functional perspective. Mol Aspects Med. 2004 Oct;25(5-6):455–73. doi: 10.1016/j.mam.2004.06.006. PMID: 15363636.; Vaz FM, Wanders RJ. Carnitine biosynthesis in mammals. Biochem J. 2002 Feb 01;361(Pt 3):417–29. PMID: 11802770; PMCID: PMC1222323.; Hulse JD, Ellis SR, Henderson LM. Carnitine biosynthesis. beta-Hydroxylation of trimethyllysine by an alpha-ketoglutarate-dependent mitochondrial dioxygenase. Journal of Biological Chemistry. 1978 Mar;253(5):1654–9. doi: 10.1016/s0021-9258(17)34915-3.; Kaufman RA, Broquist HP. Biosynthesis of carnitine in Neurospora crassa. Journal of Biological Chemistry. 1977 Nov;252(21):7437–9. doi: 10.1016/s0021-9258(17)40983-5.
L-carnitine biosynthesis

Accession ID: BioCyc:MOUSE_PWY-6100		 -
L-carnitine biosynthesis

Accession ID: BioCyc:FLY_PWY-6100		 -
L-carnitine biosynthesis

Accession ID: PlantCyc:CROSEUS_PWY-6100		 -
L-carnitine biosynthesis

Accession ID: PlantCyc:TPARVULA_PWY-6100		 -
L-carnitine biosynthesis

Accession ID: PlantCyc:CORKOAK_PWY-6100		 -
Metabolism

Accession ID: Reactome:R-BTA-1430728		 -
Amino acid and derivative metabolism

Accession ID: Reactome:R-BTA-71291
  • 10.1007/978-1-4757-0734-2_8
  • 10.1146/annurev.bi.44.070175.004441
  • 10.1177/014860719001400405
 Häussinger D. Liver glutamine metabolism. JPEN J Parenter Enteral Nutr. 1990 Jul;14(4 Suppl):56S–62S. doi: 10.1177/014860719001400405. PMID: 2205732.; Owen OE, Reichard GA, Patel MS, Boden G. Energy metabolism in feasting and fasting. Adv Exp Med Biol. 1979;111():169–88. doi: 10.1007/978-1-4757-0734-2_8. PMID: 371355.; Felig P. Amino acid metabolism in man. Annu Rev Biochem. 1975;44():933–55. doi: 10.1146/annurev.bi.44.070175.004441. PMID: 1094924.
Carnitine synthesis

Accession ID: Reactome:R-BTA-71262
  • 10.1016/0304-4165(80)90133-6
  • 10.1042/0264-6021:3610417
  • 10.1146/annurev.nutr.18.1.179
  • 10.1152/physrev.1983.63.4.1420
 Vaz FM, Wanders RJ. Carnitine biosynthesis in mammals. Biochem J. 2002 Feb 01;361(Pt 3):417–29. PMID: 11802770; PMCID: PMC1222323.; Kerner J, Hoppel C. Genetic disorders of carnitine metabolism and their nutritional management. Annu Rev Nutr. 1998;18():179–206. doi: 10.1146/annurev.nutr.18.1.179. PMID: 9706223.; Bremer J. Carnitine--metabolism and functions. Physiol Rev. 1983 Oct;63(4):1420–80. doi: 10.1152/physrev.1983.63.4.1420. PMID: 6361812.; Rebouche CJ, Engel AG. Tissue distribution of carnitine biosynthetic enzymes in man. Biochimica et Biophysica Acta (BBA) - General Subjects. 1980 Jun;630(1):22–9. doi: 10.1016/0304-4165(80)90133-6.
Metabolism

Accession ID: Reactome:R-CFA-1430728		 -
Amino acid and derivative metabolism

Accession ID: Reactome:R-DRE-71291
  • 10.1007/978-1-4757-0734-2_8
  • 10.1146/annurev.bi.44.070175.004441
  • 10.1177/014860719001400405
 Häussinger D. Liver glutamine metabolism. JPEN J Parenter Enteral Nutr. 1990 Jul;14(4 Suppl):56S–62S. doi: 10.1177/014860719001400405. PMID: 2205732.; Owen OE, Reichard GA, Patel MS, Boden G. Energy metabolism in feasting and fasting. Adv Exp Med Biol. 1979;111():169–88. doi: 10.1007/978-1-4757-0734-2_8. PMID: 371355.; Felig P. Amino acid metabolism in man. Annu Rev Biochem. 1975;44():933–55. doi: 10.1146/annurev.bi.44.070175.004441. PMID: 1094924.
Carnitine synthesis

Accession ID: Reactome:R-DRE-71262
  • 10.1016/0304-4165(80)90133-6
  • 10.1042/0264-6021:3610417
  • 10.1146/annurev.nutr.18.1.179
  • 10.1152/physrev.1983.63.4.1420
 Vaz FM, Wanders RJ. Carnitine biosynthesis in mammals. Biochem J. 2002 Feb 01;361(Pt 3):417–29. PMID: 11802770; PMCID: PMC1222323.; Kerner J, Hoppel C. Genetic disorders of carnitine metabolism and their nutritional management. Annu Rev Nutr. 1998;18():179–206. doi: 10.1146/annurev.nutr.18.1.179. PMID: 9706223.; Bremer J. Carnitine--metabolism and functions. Physiol Rev. 1983 Oct;63(4):1420–80. doi: 10.1152/physrev.1983.63.4.1420. PMID: 6361812.; Rebouche CJ, Engel AG. Tissue distribution of carnitine biosynthetic enzymes in man. Biochimica et Biophysica Acta (BBA) - General Subjects. 1980 Jun;630(1):22–9. doi: 10.1016/0304-4165(80)90133-6.
Metabolism

Accession ID: Reactome:R-MMU-1430728		 -
Amino acid and derivative metabolism

Accession ID: Reactome:R-SCE-71291
  • 10.1007/978-1-4757-0734-2_8
  • 10.1146/annurev.bi.44.070175.004441
  • 10.1177/014860719001400405
 Häussinger D. Liver glutamine metabolism. JPEN J Parenter Enteral Nutr. 1990 Jul;14(4 Suppl):56S–62S. doi: 10.1177/014860719001400405. PMID: 2205732.; Owen OE, Reichard GA, Patel MS, Boden G. Energy metabolism in feasting and fasting. Adv Exp Med Biol. 1979;111():169–88. doi: 10.1007/978-1-4757-0734-2_8. PMID: 371355.; Felig P. Amino acid metabolism in man. Annu Rev Biochem. 1975;44():933–55. doi: 10.1146/annurev.bi.44.070175.004441. PMID: 1094924.
Carnitine synthesis

Accession ID: Reactome:R-SCE-71262
  • 10.1016/0304-4165(80)90133-6
  • 10.1042/0264-6021:3610417
  • 10.1146/annurev.nutr.18.1.179
  • 10.1152/physrev.1983.63.4.1420
 Vaz FM, Wanders RJ. Carnitine biosynthesis in mammals. Biochem J. 2002 Feb 01;361(Pt 3):417–29. PMID: 11802770; PMCID: PMC1222323.; Kerner J, Hoppel C. Genetic disorders of carnitine metabolism and their nutritional management. Annu Rev Nutr. 1998;18():179–206. doi: 10.1146/annurev.nutr.18.1.179. PMID: 9706223.; Bremer J. Carnitine--metabolism and functions. Physiol Rev. 1983 Oct;63(4):1420–80. doi: 10.1152/physrev.1983.63.4.1420. PMID: 6361812.; Rebouche CJ, Engel AG. Tissue distribution of carnitine biosynthetic enzymes in man. Biochimica et Biophysica Acta (BBA) - General Subjects. 1980 Jun;630(1):22–9. doi: 10.1016/0304-4165(80)90133-6.
Metabolism

Accession ID: Reactome:R-SPO-1430728		 -
Amino acid and derivative metabolism

Accession ID: Reactome:R-CFA-71291
  • 10.1007/978-1-4757-0734-2_8
  • 10.1146/annurev.bi.44.070175.004441
  • 10.1177/014860719001400405
 Häussinger D. Liver glutamine metabolism. JPEN J Parenter Enteral Nutr. 1990 Jul;14(4 Suppl):56S–62S. doi: 10.1177/014860719001400405. PMID: 2205732.; Owen OE, Reichard GA, Patel MS, Boden G. Energy metabolism in feasting and fasting. Adv Exp Med Biol. 1979;111():169–88. doi: 10.1007/978-1-4757-0734-2_8. PMID: 371355.; Felig P. Amino acid metabolism in man. Annu Rev Biochem. 1975;44():933–55. doi: 10.1146/annurev.bi.44.070175.004441. PMID: 1094924.
Carnitine synthesis

Accession ID: Reactome:R-CFA-71262
  • 10.1016/0304-4165(80)90133-6
  • 10.1042/0264-6021:3610417
  • 10.1146/annurev.nutr.18.1.179
  • 10.1152/physrev.1983.63.4.1420
 Vaz FM, Wanders RJ. Carnitine biosynthesis in mammals. Biochem J. 2002 Feb 01;361(Pt 3):417–29. PMID: 11802770; PMCID: PMC1222323.; Kerner J, Hoppel C. Genetic disorders of carnitine metabolism and their nutritional management. Annu Rev Nutr. 1998;18():179–206. doi: 10.1146/annurev.nutr.18.1.179. PMID: 9706223.; Bremer J. Carnitine--metabolism and functions. Physiol Rev. 1983 Oct;63(4):1420–80. doi: 10.1152/physrev.1983.63.4.1420. PMID: 6361812.; Rebouche CJ, Engel AG. Tissue distribution of carnitine biosynthetic enzymes in man. Biochimica et Biophysica Acta (BBA) - General Subjects. 1980 Jun;630(1):22–9. doi: 10.1016/0304-4165(80)90133-6.
Metabolism

Accession ID: Reactome:R-DME-1430728		 -