Carbamoyl phosphate (BioCAD00000007972)

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Metabolite Card

Formula: CH4NO5P (140.9827)
SMILES: NC(=O)OP(O)(O)=O

Synonyms [en]

Carbamoyl phosphate; Carbamyl Phosphate; carbamic phosphoric monoanhydride; monocarbamoyl phosphate; PHOSPHORIC ACID MONO(FORMAMIDE)ESTER; aminocarbonyl dihydrogen phosphate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Carbamoyl phosphate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000007972). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Carbamoyl phosphate is a precursor of both arginine and pyrimidine biosynthesis. It is a labile and potentially toxic intermediate. Carbamoyl phosphate is a molecule that is involved in ridding the body of excess nitrogen in the urea cycle, and also in the synthesis of pyrimidines. It is produced from carbon dioxide, ammonia, and phosphate (from ATP) by the enzyme carbamoyl phosphate synthase. -- Wikipedia.

Mitochondria Endoplasmic reticulum
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 1067-12-5
  • CAS Registry Number: 590-55-6
  • PubChem: 278
  • ChEBI: ChEBI:17672
  • HMDB: HMDB0001096
  • KEGG: C00169
  • NCBI MeSH: Carbamyl Phosphate
  • Wikipedia: Carbamoyl phosphate
  • Wikipedia: Carbamoyl_phosphate
  • RefMet: RM0136057
  • MoNA: BAF_UVA_POS000658
  • Metlin: METLIN_3266
  • Coconut NaturalProduct: CNP0057905.0
  • Coconut NaturalProduct: CNP0209834.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R00149 6.3.4.16 carbon-dioxide:ammonia ligase (ADP-forming,carbamate-phosphorylating)
KEGG:R00150 2.7.2.2 ATP:carbamate phosphotransferase
KEGG:R00575 6.3.5.5 HCO3-:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)
KEGG:R01395 2.7.2.2 ATP:carbamate phosphotransferase
KEGG:R01396 2.1.3.8 carbamoyl-phosphate:L-lysine carbamoyltransferase
KEGG:R01397 2.1.3.2 carbamoyl-phosphate:L-aspartate carbamoyltransferase
KEGG:R01398 2.1.3.3 carbamoyl-phosphate:L-ornithine carbamoyltransferase
KEGG:R01399 2.1.3.6 carbamoyl-phosphate:putrescine carbamoyltransferase
KEGG:R01400 C00169<=>C06059
KEGG:R02937 2.1.3.5 carbamoyl-phosphate:oxamate carbamoyltransferase
KEGG:R04281 2.1.3.7 carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase
KEGG:R05230 2.1.3.7 carbamoyl-phosphate:deacetylcephalosporin C carbamoyltransferase
KEGG:R06772 2.1.3.12 carbamoyl phosphate:decarbamoylnovobiocin 3''-O-carbamoyltransferase
KEGG:R07245 2.1.3.9 carbamoyl-phosphate:N2-acetyl-L-ornithine carbamoyltransferase
KEGG:R07641 6.3.5.5 2 C00002 + C00288 + C00014<=>2 C00008 + C00009 + C00169
KEGG:R08937 2.1.3.11 carbamoyl-phosphate:N2-succinyl-L-ornithine carbamoyltransferase
KEGG:R09853 2.1.3.- carbamoyl-phosphate:20-O-methyl-19-chloroproansamitocin carbamoyltransferase
KEGG:R09858 2.1.3.- carbamoyl-phosphate:ansamitocinoside-P-3 carbamoyltransferase
KEGG:R10541 6.1.2.2 C00169 + C00002 + C00001<=>C00013 + C20684 + C00009
KEGG:R10767 6.1.2.2 tobramycin:carbamoyl-phosphate ligase (AMP,phosphate-forming)
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Organism Source

Taxonomy Source

  1. Arabidopsis thaliana [ncbi taxid: 3702]
  2. Citrullus lanatus [ncbi taxid: 3654]
  3. Escherichia coli [ncbi taxid: 562]
  4. Homo sapiens [ncbi taxid: 9606]
  5. Mus musculus [ncbi taxid: 10090]
  6. Saccharomyces cerevisiae [ncbi taxid: 4932]

Pathway Synthetic

pathway id name
BioCyc:TRYPANO_PRPP-PWY superpathway of histidine, purine, and pyrimidine biosynthesis
BioCyc:LEISH_PWY-5686 uridine-5'-phosphate biosynthesis
BioCyc:TRYPANO_ARG+POLYAMINE-SYN superpathway of arginine and polyamine biosynthesis
BioCyc:TRYPANO_PWY-5686 uridine-5'-phosphate biosynthesis
BioCyc:LEISH_PWY-4984 urea cycle
BioCyc:TRYPANO_ARGSYN-PWY arginine biosynthesis I
BioCyc:LEISH_PWY0-162 pyrimidine ribonucleotides de novo biosynthesis
BioCyc:TRYPANO_PWY0-162 pyrimidine ribonucleotides de novo biosynthesis
PathBank:SMP0000812 Arginine Metabolism
PathBank:SMP0000959 Pyrimidine Metabolism
PathBank:SMP0002064 Allantoin Degradation (Anaerobic)
Plant Reactome:R-OAU-2744345 Metabolism and regulation
Plant Reactome:R-OAU-2744343 Amino acid metabolism
Plant Reactome:R-OAU-1119444 Canavanine biosynthesis
Plant Reactome:R-OAU-1119318 Proline biosynthesis V (from arginine)
Plant Reactome:R-TAE-1119263 Arginine biosynthesis I
Plant Reactome:R-FVE-5655122 Amino acid biosynthesis
Plant Reactome:R-FVE-1119495 Citrulline biosynthesis
Plant Reactome:R-FVE-1119318 Proline biosynthesis V (from arginine)
Plant Reactome:R-MES-2744345 Metabolism and regulation
View All Pathways