ADP (BioCAD00000005922)
blood cellular cytoplasm cerebrospinal fluid (csf) saliva urine all tissues microbial natural products
Metabolite Card
Formula: C10H15N5O10P2 (427.0294)
SMILES: NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
Synonyms [en]
ADP; Adenosine 5'-diphosphate; Adenosine diphosphate; 5'-Adenylphosphoric acid; H3adp; adenosine-5'-diphosphate
Last reviewed on 2024-06-28.
Cite this Page
ADP. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000005922). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Adenosine diphosphate (ADP), also known as adenosine pyrophosphate (APP), is an important organic compound in metabolism and is essential to the flow of energy in living cells. ADP consists of three important structural components: a sugar backbone attached to adenine and two phosphate groups bonded to the 5 carbon atom of ribose. The diphosphate group of ADP is attached to the 5’ carbon of the sugar backbone, while the adenine attaches to the 1’ carbon. ADP belongs to the class of organic compounds known as purine ribonucleoside diphosphates. These are purine ribobucleotides with diphosphate group linked to the ribose moiety. It is an ester of pyrophosphoric acid with the nucleotide adenine. Adenosine diphosphate is a nucleotide. ADP exists in all living species, ranging from bacteria to humans. In humans, ADP is involved in d4-gdi signaling pathway. ADP is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ADP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine.
DBLinks
- CAS Registry Number: 58-64-0
- PubChem CID: 6022
- ChEBI: 16761
- HMDB: HMDB0001341
- LipidMaps:
- KEGG: C00008
- BioCyc:
- NCBI MeSH: Adenosine Diphosphate
- Wikipedia: Adenosine_diphosphate
Other DBLinks
- CAS Registry Number: 104746-05-6
- CAS Registry Number: 110123-09-6
- CAS Registry Number: 11062-03-6
- CAS Registry Number: 112360-08-4
- CAS Registry Number: 17791-27-4
- CAS Registry Number: 20398-34-9
- CAS Registry Number: 58-64-0
- PubChem: 3310
- PubChem: 6022
- ChEBI: ChEBI:16761
- HMDB: HMDB0001341
- KEGG: C00008
- NCBI MeSH: Adenosine Diphosphate
- Wikipedia: Adenosine_diphosphate
- DrugBank: DB03431
- DrugBank: DB16833
- RefMet: RM0032913
- MoNA: CCMSLIB00000577937
- MoNA: CCMSLIB00000578171
- MoNA: CCMSLIB00005464581
- MoNA: EMBL-MCF_spec112468
- MoNA: EMBL-MCF_spec112521
- MoNA: EMBL-MCF_spec365532
- MoNA: EMBL-MCF_spec365539
- MoNA: EMBL-MCF_spec365571
- MoNA: EMBL-MCF_spec365585
- MoNA: EMBL-MCF_spec37370
- MoNA: EMBL-MCF_spec394025
- MoNA: EMBL-MCF_spec394038
- MoNA: EMBL-MCF_spec394047
- MoNA: EMBL-MCF_spec394067
- MoNA: EMBL_MCF_2_0_HRMS_Library000268
- MoNA: HMDB0001341_ms_ms_1522
- MoNA: HMDB0001341_ms_ms_1523
- MoNA: HMDB0001341_ms_ms_1524
- MoNA: KNA00824
- MoNA: KNA00825
- MoNA: MoNA024088
- MoNA: MoNA024135
- MoNA: MoNA024145
- MoNA: MoNA024181
- MoNA: MoNA033880
- MoNA: MoNA033882
- MoNA: MoNA033885
- MoNA: MoNA037817
- MoNA: MoNA_0006813
- MoNA: MoNA_0006815
- MoNA: MoNA_0006816
- MoNA: MoNA_0006817
- MoNA: MoNA_0006818
- MoNA: MoNA_0006819
- MoNA: MoNA_0007068
- MoNA: MoNA_0007069
- MoNA: MoNA_0007070
- MoNA: MoNA_0007071
- MoNA: MoNA_0007072
- MoNA: MoNA_0007073
- MoNA: MoNA_0008532
- MoNA: MoNA_0008534
- MoNA: MoNA_0008535
- MoNA: MoNA_0008536
- MoNA: MoNA_0008537
- MoNA: MoNA_0008538
- MoNA: MoNA_0008813
- MoNA: MoNA_0008814
- MoNA: MoNA_0008815
- MoNA: MoNA_0008816
- MoNA: MoNA_0008817
- MoNA: MoNA_0008818
- MoNA: MoNA_0009197
- MoNA: MoNA_0009198
- MoNA: MoNA_0009201
- MoNA: PR100514
- MoNA: PS010901
- MoNA: PS010902
- MoNA: PS010903
- MoNA: PS010904
- MoNA: PS010905
- MoNA: PS010906
- MoNA: PS010907
- MoNA: PS010908
- MoNA: VF-NPL-LTQ000095
- MoNA: VF-NPL-LTQ000096
- Metlin: METLIN_34522
- Coconut NaturalProduct: CNP0404212.1
- Coconut NaturalProduct: CNP0404212.2
- Coconut NaturalProduct: CNP0404212.3
- Coconut NaturalProduct: CNP0404212.5
Class / Ontology
- WishartLab ClassyFire: [Purine ribonucleotides] Purine ribonucleotides
- RefMet: [Purine rNDP] Purine rNDP
- ChEBI: [CHEBI:16761] ADP
- Coconut NaturalProduct: [Purine nucleos(t)ides] Purine nucleos(t)ides
| ID | EC Number | Name |
|---|---|---|
| KEGG:R00002 | 1.18.6.1 | reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing) |
| KEGG:R00076 | 2.7.11.19 | ATP:phosphorylase-b phosphotransferase; |
| KEGG:R00086 | 3.6.1.5 | ATP phosphohydrolase |
| KEGG:R00104 | 2.7.1.23 | ATP:NAD+ 2'-phosphotransferase |
| KEGG:R00105 | 2.7.1.86 | ATP:NADH 2'-phosphotransferase |
| KEGG:R00122 | 3.6.1.5 | ADP phosphohydrolase |
| KEGG:R00123 | 3.5.4.7 | ADP aminohydrolase |
| KEGG:R00124 | 2.7.4.6 | ATP:ADP phosphatransferase |
| KEGG:R00125 | 3.6.1.41 | P1,P4-bis(5'-adenosyl)-tetraphosphate nucleotidebisphosphohydrolase |
| KEGG:R00126 | 2.7.7.53 | ADP:ATP adenylyltransferase |
| KEGG:R00127 | 2.7.4.3 | ATP:AMP phosphotransferase |
| KEGG:R00129 | 4.2.1.93 | (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide hydro-lyase (ATP-hydrolysing, NADH-forming) |
| KEGG:R00130 | 2.7.1.24 | ATP:dephospho-CoA 3'-phosphotransferase |
| KEGG:R00139 | 2.7.4.6 | ATP:2'-deoxy-5-hydroxymethylcytidine-5'-diphosphate phosphotransferase |
| KEGG:R00140 | 2.7.4.12 | ATP:5-hydroxymethyldeoxycytidylate phosphotransferase |
| KEGG:R00141 | 2.7.3.8 | ATP:ammonia phosphotransferase |
| KEGG:R00149 | 6.3.4.16 | carbon-dioxide:ammonia ligase (ADP-forming,carbamate-phosphorylating) |
| KEGG:R00150 | 2.7.2.2 | ATP:carbamate phosphotransferase |
| KEGG:R00156 | 2.7.4.6 | ATP:UDP phosphotransferase |
| KEGG:R00157 | 2.7.4.10 | uridine triphosphate:AMP phosphotransferase; |
Taxonomy Source
- Escherichia coli [ncbi taxid: 562]
- Homo sapiens [ncbi taxid: 9606]
- Lentinus edodes [ncbi taxid: ]
- Mus musculus [ncbi taxid: 10090]
- Escherichia coli [ncbi taxid: 562]
- FOOD SAKE [ncbi taxid: ]
Pathway Synthetic
| pathway id | name |
|---|---|
| BioCyc:ARA_PWY-7356 | thiamine salvage IV (yeast) |
| BioCyc:ARA_PWY-6910 | hydroxymethylpyrimidine salvage |
| BioCyc:ARA_PWY-5687 | pyrimidine ribonucleotides interconversion |
| BioCyc:ARA_PWY-6890 | 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis |
| BioCyc:ARA_PWY-4562 | lipid-dependent phytate biosynthesis II (via Ins(1,3,4)P3) |
| BioCyc:ARA_THRESYN-PWY | superpathway of L-threonine biosynthesis |
| BioCyc:ARA_PWY-4541 | lipid-dependent phytate biosynthesis I (via Ins(1,4,5)P3) |
| BioCyc:ARA_PWY-7196 | superpathway of pyrimidine ribonucleosides salvage |
| BioCyc:ARA_PWY-3821 | D-galactose degradation III |
| BioCyc:ARA_PWY-2161B-PMN | folate polyglutamylation II |
| BioCyc:ARA_GLUTORN-PWY | L-ornithine biosynthesis I |
| BioCyc:ARA_PWY-7227 | adenosine deoxyribonucleotides de novo biosynthesis |
| BioCyc:ARA_PWY-5530 | sorbitol biosynthesis II |
| BioCyc:ARA_HOMOSERSYN-PWY | L-homoserine biosynthesis |
| BioCyc:ARA_PWYQT-4481 | TCA cycle variation V (plant) |
| BioCyc:ARA_ARGININE-SYN4-PWY | L-ornithine biosynthesis II |
| BioCyc:ARA_PWY-1722 | formate assimilation into 5,10-methylenetetrahydrofolate |
| BioCyc:ARA_PWY-4 | UDP-D-galacturonate biosynthesis II (from D-galacturonate) |
| BioCyc:ARA_PWY-6619 | adenine and adenosine salvage VI |
| BioCyc:ARA_PWY-4261 | glycerol degradation I |