TCA cycle variation V (plant)

Tronconi MA, Gerrard Wheeler MC, Maurino VG, Drincovich MF, Andreo CS. NAD-malic enzymes of Arabidopsis thaliana display distinct kinetic mechanisms that support differences in physiological control. Biochem J. 2010 Sep 01;430(2):295–303. doi: 10.1042/bj20100497. PMID: 20528775.; Tronconi MA, Maurino VG, Andreo CS, Drincovich MF. Three Different and Tissue-specific NAD-Malic Enzymes Generated by Alternative Subunit Association in Arabidopsis thaliana. Journal of Biological Chemistry. 2010 Apr;285(16):11870–9. doi: 10.1074/jbc.m109.097477.; Tronconi MA, Fahnenstich H, Gerrard Weehler MC, Andreo CS, Flügge UI, Drincovich MF, Maurino VG. Arabidopsis NAD-malic enzyme functions as a homodimer and heterodimer and has a major impact on nocturnal metabolism. Plant Physiol. 2008 Apr;146(4):1540–52. PMID: 18223148; PMCID: PMC2287332.; Grover SD, Canellas PF, Wedding RT. Purification of NAD malic enzyme from potato and investigation of some physical and kinetic properties. Archives of Biochemistry and Biophysics. 1981 Jul;209(2):396–407. doi: 10.1016/0003-9861(81)90297-6.; Day DA, Hanson JB. Pyruvate and malate transport and oxidation in corn mitochondria. Plant Physiol. 1977 Apr;59(4):630–5. PMID: 16659908; PMCID: PMC542463.; Coleman JOD, Palmer JM. The Oxidation of Malate by Isolated Plant Mitochondria. European Journal of Biochemistry. 1972 Apr;26(4):499–509. doi: 10.1111/j.1432-1033.1972.tb01792.x.; Macrae AR, Moorhouse R. The Oxidation of Malate by Mitochondria Isolated from Cauliflower Buds. European Journal of Biochemistry. 1970 Sep;16(1):96–102. doi: 10.1111/j.1432-1033.1970.tb01058.x.

Metabolites

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Ubiquinone-1

Formula: C14H18O4 (250.1205028)

CAS ID: 727-81-1

QH(2)

Formula: C14H20O4 (252.136152)

CAS ID: 52590-98-4

oxaloacetate(2-)

Formula: C4H2O5 (129.9902242)

CAS ID: 149-63-3

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4

butenedioate

Formula: C4H2O4 (113.99530920000001)

CAS ID: 17013-01-3

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

citrate(3-)

Formula: C6H5O7 (189.00352800000002)

CAS ID: 126-44-3

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

beta-D-fructofuranose 1,6-bisphosphate(4-)

Formula: C6H10O12P2 (335.96475200000003)

CAS ID: 488-69-7



Enzyme

EC Number name full name note
1.1.1.37 malate dehydrogenase (S)-malate:NAD+ oxidoreductase
1.1.1.39 malate dehydrogenase (decarboxylating) (S)-malate:NAD+ oxidoreductase (decarboxylating)
1.3.5.1 succinate dehydrogenase succinate:quinone oxidoreductase
2.3.3.16 citrate synthase (unknown stereospecificity) acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
4.2.1.2 fumarate hydratase (S)-malate hydro-lyase (fumarate-forming)
6.2.1.5 succinate-CoA ligase (ADP-forming) succinate:CoA ligase (ADP-forming)


Proteins

Protein ID name full name