EC: 6.3.4.2

CTP synthase (glutamine hydrolysing) (UTP:ammonia ligase (ADP-forming))

enzyme lambda metabolic reaction experiment
uniprot:Q9CI75 [CTP synthase(Enzyme) wildtype]

NH3 + UTP + ATP -> Phosphate + ADP + CTP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R359M]

ATP + UTP + NH3 -> ADP + Phosphate + CTP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R359P]

NH3 + UTP + ATP -> CTP + Phosphate + ADP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant G360A]

ATP + NH3 + UTP -> ADP + CTP + Phosphate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) wildtype]

ATP + UTP + NH3 -> Phosphate + ADP + CTP		 (( (( (kcat * E) ) * S) ) / (( (Km + S) ) + (S * (( (S / Ki) ) ^ n)))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) wildtype]

UTP + ATP + NH3 -> CTP + ADP + Phosphate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant G360P]

ATP + UTP + NH3 -> CTP + Phosphate + ADP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant G360P]

NH3 + UTP + ATP -> Phosphate + CTP + ADP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R359M]

UTP + ATP + NH3 -> CTP + Phosphate + ADP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant E362Q]

UTP + NH3 + ATP -> ADP + CTP + Phosphate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant G360A]

NH3 + UTP + ATP -> CTP + ADP + Phosphate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R359P]

UTP + ATP + NH3 -> Phosphate + ADP + CTP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant E362Q]

NH3 + ATP + UTP -> ADP + CTP + Phosphate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) wildtype]

ATP + L_Glutamine + UTP + H2O -> Phosphate + CTP + ADP + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant G360A]

L_Glutamine + ATP + H2O + UTP -> CTP + ADP + L_Glutamate + Phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R359P]

UTP + H2O + ATP + L_Glutamine -> CTP + ADP + Phosphate + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R359M]

ATP + H2O + UTP + L_Glutamine -> Phosphate + ADP + L_Glutamate + CTP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant G360P]

NH3 + UTP + ATP -> CTP + ADP + Phosphate		 (( (( (kcat * E) ) * S) ) / (( (Km + S) ) + (S * (( (S / Ki) ) ^ n)))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R359P]

ATP + NH3 + UTP -> Phosphate + ADP + CTP		 (( (( (kcat * E) ) * S) ) / (( (Km + S) ) + (S * (( (S / Ki) ) ^ n)))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant E362Q]

ATP + UTP + NH3 -> ADP + Phosphate + CTP		 (( (( (kcat * E) ) * S) ) / (( (Km + S) ) + (S * (( (S / Ki) ) ^ n)))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant G360A]

ATP + UTP + NH3 -> Phosphate + ADP + CTP		 (( (( (kcat * E) ) * S) ) / (( (Km + S) ) + (S * (( (S / Ki) ) ^ n)))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R359M]

NH3 + ATP + UTP -> ADP + Phosphate + CTP		 (( (( (kcat * E) ) * S) ) / (( (Km + S) ) + (S * (( (S / Ki) ) ^ n)))) buffer: 50 mM HEPES, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

UTP + L_Glutamine + ATP + H2O -> Phosphate + ADP + CTP + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

ATP + H2O + L_Glutamine + UTP -> CTP + ADP + L_Glutamate + Phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

ATP + H2O + L_Glutamine + UTP -> Phosphate + CTP + ADP + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

UTP + ATP + L_Glutamine + H2O -> Phosphate + L_Glutamate + CTP + ADP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

L_Glutamine + H2O + ATP + UTP -> L_Glutamate + ADP + CTP + Phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant G360P]

L_Glutamine + ATP + UTP + H2O -> Phosphate + L_Glutamate + ADP + CTP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant E362Q]

ATP + UTP + H2O + L_Glutamine -> Phosphate + ADP + CTP + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

L_Glutamine + Adenosine_5_O_(3_thiotriphosphate) + UTP + H2O -> CTP + ADP + Thiophosphate + L_Glutamate		 (( (( (kcat * E) ) * A) ) / (Ka + A)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

L_Glutamine + UTP + Adenosine_5_O_(3_thiotriphosphate) + H2O -> CTP + Thiophosphate + ADP + L_Glutamate		 (( (( (kcat * E) ) * A) ) / (Ka + A)) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

L_Glutamine + H2O + UTP + ATP -> L_Glutamate + Phosphate + ADP + CTP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

L_Glutamine + H2O + ATP + UTP -> Phosphate + L_Glutamate + CTP + ADP		 (( (kcat1 + (( (kcat2 * A) ) / (Ka + A))) ) * E) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

ATP + H2O + UTP + L_Glutamine -> CTP + ADP + Phosphate + L_Glutamate		 (( (kcat1 + (( (kcat2 * A) ) / (Ka + A))) ) * E) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

UTP + H2O + ATP + L_Glutamine -> L_Glutamate + CTP + ADP + Phosphate		 (( (kcat1 + (( (kcat2 * A) ) / (Ka + A))) ) * E) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

ATP + L_Glutamine + UTP + H2O -> L_Glutamate + Phosphate + ADP + CTP		 (( (kcat1 + (( (kcat2 * A) ) / (Ka + A))) ) * E) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

H2O + L_Glutamine + ATP + UTP -> L_Glutamate + ADP + Phosphate + CTP		 (( (kcat1 + (( (kcat2 * A) ) / (Ka + A))) ) * E) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

H2O + UTP + ATP + L_Glutamine -> ADP + CTP + L_Glutamate + Phosphate		 (( (kcat1 + (( (kcat2 * A) ) / (Ka + A))) ) * E) buffer: 50 mM HEPES, 2 mM dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

H2O + L_Glutamine + ATP + UTP -> CTP + Phosphate + ADP + L_Glutamate		 (( (kcat * A) ) / (Km_A + A)) buffer: 50 mM Hepes, 2 mM DTT, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

Hydroxylamine + UTP + ATP -> Phosphate + N4_Hydroxyl_CTP + ADP		 (( (( (k_inh * Ki) ) / (Ki + I)) ) + k_res) buffer: 50 mM Hepes, 2 mM DTT, 20 mM MgCl2, 50 mM KCl
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

H2O + UTP + ATP + L_Glutamine -> Phosphate + ADP + L_Glutamate + CTP		 (kcat_1 + (( (kcat_2 * K) ) / (K_k + K))) buffer: 50 mM Hepes, 2 mM DTT, 20 mM MgCl2, 50 mM KCl
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

ATP + NH3 + UTP -> Phosphate + ADP + CTP		 (( (( (k_inh * Ki) ) / (Ki + I)) ) + k_res) buffer: 50 mM Hepes, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

Hydroxylamine + ATP + UTP -> N4_Hydroxyl_CTP + Phosphate + ADP		 (( (( (k_inh * Ki) ) / (Ki + I)) ) + k_res) buffer: 50 mM Hepes, 2 mM DTT, 20 mM MgCl2, 50 mM KCl
PH: 8
Temperature: 30
- [CTP synthase(Enzyme) mutant L109A]

L_Glutamine + UTP + H2O + ATP -> L_Glutamate + Phosphate + CTP + ADP		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2, 0.25 mM GTP
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

ATP + H2O + L_Glutamine + UTP -> Phosphate + L_Glutamate + CTP + ADP		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2, 0.25 mM GTP
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

NH3 + UTP + ATP -> Phosphate + ADP + CTP		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) mutant L109A]

ATP + UTP + NH3 -> CTP + Phosphate + ADP		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) mutant L109A]

UTP + ATP + Hydroxylamine -> N4_Hydroxyl_CTP + ADP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

ATP + UTP + Hydroxylamine -> N4_Hydroxyl_CTP + Phosphate + ADP		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

ATP + UTP + Hydrazine -> Phosphate + N4_Amino_CTP + ADP		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

L_gamma_Glutamyl_hydroxamate + UTP + ATP + H2O -> L_Glutamate + Phosphate + ADP + N4_Hydroxyl_CTP		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2, 0.25 mM GTP
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) mutant L109A]

ATP + UTP + L_gamma_Glutamyl_hydroxamate + H2O -> N4_Hydroxyl_CTP + ADP + L_Glutamate + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2, 0.25 mM GTP
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

H2O + L_gamma_Glutamyl_hydrazide + UTP + ATP -> N4_Amino_CTP + ADP + Phosphate + L_Glutamate		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2, 0.25 mM GTP
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

H2O + L_Glutamine -> NH3 + L_Glutamate		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2, 1 mM ATP, 1 mM UTP, 0.25 mM GTP
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) mutant L109A]

L_Glutamine + H2O -> L_Glutamate + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2, 1 mM ATP, 1 mM UTP, 0.25 mM GTP
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) mutant L109A]

UTP + Hydrazine + ATP -> ADP + N4_Amino_CTP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

L_gamma_Glutamyl_hydroxamate + H2O -> L_Glutamate + Hydroxylamine		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2, 1 mM ATP, 1 mM UTP, 0.25 mM GTP
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) mutant L109A]

L_gamma_Glutamyl_hydroxamate + H2O -> Hydroxylamine + L_Glutamate		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2, 1 mM ATP, 1 mM UTP, 0.25 mM GTP
PH: 8
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

H2O + L_gamma_Glutamyl_hydrazide -> L_Glutamate + Hydrazine		 (( (Vmax * S) ) / (Km + S)) buffer: 70 mM HEPES, 0.5 mM EGTA, 10 mM MgCl2, 1 mM ATP, 1 mM UTP, 0.25 mM GTP
PH: 8
Temperature: 37
uniprot:O87761 [GTP]

UTP + H2O + ATP + L_Glutamine -> Phosphate + ADP + CTP + L_Glutamate		 (( (( (Vapp * (A ^ hA)) ) * (B ^ hB)) ) / (( (( (( (( (S05A ^ hA) ) * (S05B ^ hB)) ) + (( (S05A ^ hA) ) * (B ^ hB))) ) + (( (S05B ^ hB) ) * (A ^ hA))) ) + (( (A ^ hA) ) * (B ^ hB)))) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:O87761 [GTP]

L_Glutamine + ATP + UTP + H2O -> CTP + ADP + L_Glutamate + Phosphate		 (( (Vapp * (C ^ n)) ) / (( (S05 ^ n) ) + (C ^ n))) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:O87761 [GTP]

UTP + ATP + L_Glutamine + H2O -> L_Glutamate + CTP + Phosphate + ADP		 (( (Vapp * C) ) / (Km + C)) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:O87761 [Mg2+]

ATP + NH3 + UTP -> CTP + ADP + Phosphate		 (( (Vapp * C) ) / (Km + C)) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:O87761 [GTP]

H2O + UTP + L_Glutamine + ATP -> CTP + ADP + L_Glutamate + Phosphate		 (( (Vapp * (B ^ n)) ) / (( (S05 ^ n) ) + (B ^ n))) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:O87761 [GTP]

ATP + UTP + L_Glutamine + H2O -> CTP + ADP + Phosphate + L_Glutamate		 (( (Vapp * (IC50 ^ n)) ) / (( (IC50 ^ n) ) + (I ^ n))) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:O87761 [GTP]

L_Glutamine + H2O + UTP + ATP -> Phosphate + ADP + L_Glutamate + CTP		 (( (Vapp * (C ^ n)) ) / (( (S05 ^ n) ) + (C ^ n))) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:O87761 [GTP]

UTP + ATP + L_Glutamine + H2O -> Phosphate + ADP + CTP + L_Glutamate		 (( (Vapp * C) ) / (KA + C)) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:O87761 [GTP]

L_Glutamine + UTP + H2O + ATP -> CTP + ADP + Phosphate + L_Glutamate		 (( (Vapp * C) ) / (KA + C)) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:O87761 [GTP]

dUTP + L_Glutamine + ATP + H2O -> dCTP + ADP + Phosphate + L_Glutamate		 (( (Vapp * (B ^ n)) ) / (( (S05 ^ n) ) + (B ^ n))) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:O87761 [GTP]

ATP + L_Glutamine + dUTP + H2O -> Phosphate + ADP + L_Glutamate + dCTP		 (( (Vapp * (IC50 ^ n)) ) / (( (IC50 ^ n) ) + (I ^ n))) buffer: 50 mM Hepes, 2 mM DTT
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) wildtype]

ATP + UTP + NH3 -> ADP + Phosphate + CTP		 (( (Vapp * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R433M]

UTP + NH3 + ATP -> Phosphate + ADP + CTP		 (( (Vapp * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) wildtype]

NH3 + UTP + ATP -> Phosphate + ADP + CTP		 (( (Vapp * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant T431V]

UTP + ATP + NH3 -> CTP + ADP + Phosphate		 (( (Vapp * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant T431V]

NH3 + UTP + ATP -> ADP + Phosphate + CTP		 (( (Vapp * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R433M]

ATP + NH3 + UTP -> Phosphate + CTP + ADP		 (( (Vapp * S) ) / (( (Km + S) ) + (S * (( (S / Ki) ) ^ n)))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) wildtype]

NH3 + UTP + ATP -> Phosphate + CTP + ADP		 (( (Vapp * S) ) / (( (Km + S) ) + (S * (( (S / Ki) ) ^ n)))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant T431V]

UTP + ATP + NH3 -> Phosphate + CTP + ADP		 (( (Vapp * S) ) / (( (Km + S) ) + (S * (( (S / Ki) ) ^ n)))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) mutant R433M]

ATP + UTP + NH3 -> ADP + Phosphate + CTP		 (( (Vapp * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

UTP + L_Glutamine + ATP + H2O -> CTP + ADP + Phosphate + L_Glutamate		 (V1 + (( (V2 * A) ) / (KA + A))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

H2O + L_Glutamine + ATP + UTP -> L_Glutamate + Phosphate + CTP + ADP		 (V1 + (( (V2 * A) ) / (KA + A))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

ATP + UTP + H2O + L_Glutamine -> CTP + L_Glutamate + Phosphate + ADP		 (V1 + (( (V2 * A) ) / (KA + A))) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

UTP + L_Glutamine + ATP + H2O -> CTP + ADP + L_Glutamate + Phosphate		 (( (V * S) ) / (Km + S)) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

ATP + L_Glutamine + H2O + UTP -> CTP + L_Glutamate + ADP + Phosphate		 (( (V * S) ) / (Km + S)) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

ATP + H2O + UTP + L_Glutamine -> CTP + L_Glutamate + Phosphate + ADP		 (( (V * S) ) / (Km + S)) buffer: 50 mM Hepes, 2 mM dithiothreitol
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

H2O + L_Glutamine -> NH3 + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) wildtype]

H2O + L_Glutamine -> L_Glutamate + NH3		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

L_Glutamine + UTP + ATP + H2O -> CTP + L_Glutamate + ADP + Phosphate		 (( (kcat1 * E) ) + (( (( (kcat2 * E) ) * A) ) / (Ka + A))) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

H2O + L_Glutamine + UTP + ATP -> CTP + L_Glutamate + ADP + Phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

H2O + L_Glutamine + UTP + ATP -> ADP + CTP + L_Glutamate + Phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [GTP]

L_Glutamine + H2O + UTP + ATP -> CTP + Phosphate + L_Glutamate + ADP		 (( (kcat1 * E) ) + (( (( (kcat2 * E) ) * A) ) / (Ka + A))) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [Adenosine 5-O-(3-thiotriphosphate)]

H2O + L_Glutamine -> NH3 + L_Glutamate		 (( (kcat1 * E) ) + (( (( (kcat2 * E) ) * A) ) / (Ka + A))) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [Adenosine 5-O-(3-thiotriphosphate)]

L_Glutamine + H2O -> NH3 + L_Glutamate		 (( (kcat1 * E) ) + (( (( (kcat2 * E) ) * A) ) / (Ka + A))) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [Adenosine 5-O-(3-thiotriphosphate)]

L_Glutamine + H2O -> NH3 + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [CTP synthase(Enzyme) wildtype]

ATP + H2O + L_Glutamine + UTP -> Phosphate + CTP + L_Glutamate + ADP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
uniprot:Q9CI75 [Adenosine 5-O-(3-thiotriphosphate)]

L_Glutamine + H2O -> NH3 + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Hepes, 2 mM Dithiothreitol, 20 mM MgCl2
PH: 8
Temperature: 30
- [CTP synthase(Enzyme) wildtype]

ATP + NH3 + UTP -> CTP + ADP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 35 mM Tris-Cl, 55 mM L-glutamine, 18 mM MgCl2
PH: 7.2
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

UTP + NH3 + ATP -> CTP + ADP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 35 mM Tris-Cl, 50 mM 2-mercaptoethanol, 55 mM L-glutamine, 18 mM MgCl2
PH: 7.2
Temperature: 37
- [CTP synthase(Enzyme) wildtype]

UTP + ATP + NH3 -> Phosphate + ADP + CTP		 (( (Vmax * S) ) / (Km + S)) buffer: 35 mM Tris-Cl, 50 mM 2-mercaptoethanol, 55 mM L-glutamine, 18 mM MgCl2
PH: 7.2
Temperature: 37
uniprot:P0A7E5 [GTP]

UTP + ATP + L_Glutamine + H2O -> ADP + L_Glutamate + Phosphate + CTP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [GTP]

L_Glutamine + ATP + H2O + UTP -> Phosphate + ADP + CTP + L_Glutamate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [GTP]

ATP + UTP + H2O + L_Glutamine -> ADP + Phosphate + L_Glutamate + CTP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [GTP]

H2O + UTP + L_Glutamine + ATP -> ADP + L_Glutamate + CTP + Phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) mutant K306A]

ATP + NH3 + UTP -> CTP + Phosphate + ADP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) wildtype]

NH3 + UTP + ATP -> Phosphate + ADP + CTP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) wildtype]

UTP + ATP + NH3 -> Phosphate + ADP + CTP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) mutant K306A]

UTP + ATP + NH3 -> Phosphate + CTP + ADP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) mutant K297A]

ATP + UTP + NH3 -> Phosphate + ADP + CTP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) mutant K306A]

ATP + NH3 + UTP -> Phosphate + ADP + CTP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) wildtype]

UTP + ATP + NH3 -> CTP + ADP + Phosphate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) mutant K306A]

ATP + UTP + NH3 -> CTP + ADP + Phosphate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) wildtype]

UTP + NH3 + ATP -> ADP + CTP + Phosphate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) mutant K297A]

UTP + ATP + NH3 -> Phosphate + CTP + ADP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37
uniprot:P0A7E5 [CTP synthase(Enzyme) mutant K297A]

NH3 + ATP + UTP -> Phosphate + ADP + CTP		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 70 mM Hepes, 0.5 mM EGTA, 10 mM MgCl2
PH: 8
Temperature: 37

Pathways

pathway id name
BioCyc:META_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:ECO_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:YEAST_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:MTBH37RV_GLUTAMINDEG-PWY L-glutamine degradation I
BioCyc:MTBCDC1551_GLUTAMINDEG-PWY L-glutamine degradation I
BioCyc:HPY_GLUTORN-PWY L-ornithine biosynthesis I
BioCyc:HPY_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:HPY_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:ANTHRA_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:MOUSE_PWY-5687 pyrimidine ribonucleotides interconversion
BioCyc:MOUSE_PWY0-162 pyrimidine ribonucleotides de novo biosynthesis
BioCyc:BSUB_PWY-7177 UTP and CTP dephosphorylation II
BioCyc:SYNEL_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:BTHE_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:BTHE_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:BTHE_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:CORYNE_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:GCF_000013425_PWY-7185 UTP and CTP dephosphorylation I
BioCyc:GCF_000013425_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:GCF_000013425_GLUTAMINDEG-PWY L-glutamine degradation I
BioCyc:HUMAN_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:HUMAN_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:HUMAN_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:META_PWY-7196 superpathway of pyrimidine ribonucleosides salvage
BioCyc:ECO_PWY-7196 superpathway of pyrimidine ribonucleosides salvage
BioCyc:MTBH37RV_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:MTBH37RV_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:MTBH37RV_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:MTBCDC1551_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:MTBCDC1551_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:ECOO157_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:ECOO157_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:ECOL199310_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:ECOL199310_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:BSUB_PWY-5687 pyrimidine ribonucleotides interconversion
BioCyc:CORYNE_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:CORYNE_PWY-7185 UTP and CTP dephosphorylation I
BioCyc:CORYNE_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:HUMAN_PWY-7185 UTP and CTP dephosphorylation I
BioCyc:META_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:META_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:META_PWY-7177 UTP and CTP dephosphorylation II
BioCyc:META_PWY-7185 UTP and CTP dephosphorylation I
BioCyc:ECO_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:VCHO_PWY-7185 UTP and CTP dephosphorylation I
BioCyc:VCHO_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:MTBH37RV_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:MTBCDC1551_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:MTBCDC1551_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:HPY_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:ECOO157_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:CAULO_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:CAULO_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:CAULO_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:ANTHRA_PWY-7185 UTP and CTP dephosphorylation I
BioCyc:ANTHRA_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:ECOL316407_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:CAULONA1000_PWY-5687 pyrimidine ribonucleotides interconversion
BioCyc:CAULONA1000_PWY0-162 pyrimidine ribonucleotides de novo biosynthesis
BioCyc:BTHE_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:CORYNE_GLUTAMINDEG-PWY L-glutamine degradation I
BioCyc:GCF_000013425_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:GCF_000013425_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:GCF_000013425_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:META_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:ECO_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:ECO_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:YEAST_PYRIMID-RNTSYN-PWY de novo biosynthesis of pyrimidine ribonucleotides
BioCyc:YEAST_PWY-7177 UTP and CTP dephosphorylation II
BioCyc:VCHO_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:ECOO157_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:ECOL199310_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:ECOL199310_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:CAULO_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:ANTHRA_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
BioCyc:ANTHRA_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:SYNEL_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis
BioCyc:SYNEL_PWY-7208 superpathway of pyrimidine nucleobases salvage
BioCyc:ECOL316407_PWY-7176 UTP and CTP de novo biosynthesis
BioCyc:BTHE_GLUTAMINDEG-PWY glutamine degradation I
BioCyc:CORYNE_PWY-7208 superpathway of pyrimidine nucleobases salvage
WikiPathways:WP2472 Escherichia coli K-12 peripherome
PathBank:SMP0000959 Pyrimidine Metabolism
Reactome:R-BTA-1430728 Metabolism
Reactome:R-GGA-15869 Nucleotide metabolism
Reactome:R-GGA-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-MMU-1430728 Metabolism
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-15869 Nucleotide metabolism
Reactome:R-SPO-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-DDI-15869 Nucleotide metabolism
Reactome:R-DDI-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-DME-1430728 Metabolism
Reactome:R-SCE-1430728 Metabolism
Reactome:R-BTA-15869 Nucleotide metabolism
Reactome:R-BTA-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-DRE-1430728 Metabolism
Reactome:R-DME-15869 Nucleotide metabolism
Reactome:R-DME-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-GGA-1430728 Metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-SCE-15869 Nucleotide metabolism
Reactome:R-SCE-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-DRE-15869 Nucleotide metabolism
Reactome:R-DRE-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-DDI-1430728 Metabolism
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-15869 Nucleotide metabolism
Reactome:R-HSA-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-MMU-15869 Nucleotide metabolism
Reactome:R-MMU-499943 Interconversion of nucleotide di- and triphosphates
Reactome:R-RNO-15869 Nucleotide metabolism
Reactome:R-RNO-499943 Interconversion of nucleotide di- and triphosphates
WikiPathways:WP5298 Dravet syndrome: Scn1a-A1783V point mutation model
PathBank:SMP0121324 Pyrimidine Metabolism
PathBank:SMP0000178 Dihydropyrimidinase Deficiency
PathBank:SMP0000046 Pyrimidine Metabolism
PathBank:SMP0000219 UMP Synthase Deficiency (Orotic Aciduria)
PathBank:SMP0000446 Gemcitabine Action Pathway
PathBank:SMP0000202 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
PathBank:SMP0000172 beta-Ureidopropionase Deficiency
PathBank:SMP0000603 Gemcitabine Metabolism Pathway