EC: 2.7.8.11

CDP-diacylglycerol-inositol 3-phosphatidyltransferase (CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase)

enzyme lambda metabolic reaction experiment
uniprot:Q8LBA6 [Mn2+]

CDP_1,2_diacylglycerol + myo_Inositol -> CMP + 1_Phosphatidyl_D_myo_inositol		 (( (( (kcat * E) ) * B) ) / (Km + B)) buffer: 50 mM Tris-HCl, 2.4 mM Triton X-100, 5 mM EDTA
PH: 8
Temperature: 30
uniprot:Q8LBA6 [Mn2+]

myo_Inositol + CDP_1,2_diacylglycerol -> CMP + 1_Phosphatidyl_D_myo_inositol		 (( (( (kcat * E) ) * B) ) / (Km + B)) buffer: 50 mM Tris-HCl, 2.4 mM Triton X-100, 5 mM EDTA
PH: 8
Temperature: 30
uniprot:Q8LBA6 [Mn2+]

CDP_1,2_diacylglycerol + myo_Inositol -> 1_Phosphatidyl_D_myo_inositol + CMP		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 2.4 mM Triton X-100, 5 mM EDTA
PH: 8
Temperature: 30
uniprot:P06197 [CDP-diacylglycerol---inositol 3-phosphatidyltransferase(Enzyme) wildtype]

myo_Inositol + CDP_1,2_diacylglycerol -> CMP + 1_Phosphatidyl_D_myo_inositol		 (( (Vmax * A) ) / (Km + A)) buffer: 30 mM Tris-HCl, 3 mM MnCl2, 2 mM DTT, 0.26% (w/v) Triton X-100
PH: 8
Temperature: 30
uniprot:P06197 [CDP-diacylglycerol---inositol 3-phosphatidyltransferase(Enzyme) wildtype]

1_Phosphatidyl_D_myo_inositol + CMP -> myo_Inositol + CDP_1,2_diacylglycerol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 3 mM MnCl2, 2 mM DTT, 0.26% (w/v) Triton X-100
PH: 8
Temperature: 30
uniprot:P70500 [Mg2+]

myo_Inositol + CDP_1,2_diacylglycerol -> 1_Phosphatidyl_D_myo_inositol + CMP		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM glycylglycine, asolectin (14.3 µg/ml of phosphorus), 0.3% Triton X-100
PH: 8.6
Temperature: 37
uniprot:P70500 [Mg2+]

myo_Inositol + CDP_1,2_diacylglycerol -> 1_Phosphatidyl_D_myo_inositol + CMP		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM glycylglycine, asolectin (14.3 µg/ml of phosphorus), 0.3% Triton X-100
PH: 8.6
Temperature: 37
uniprot:P70500 [Mg2+]

CDP_1,2_diacylglycerol + myo_Inositol -> 1_Phosphatidyl_D_myo_inositol + CMP		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM glycylglycine, 0.5 mM dithiothreitol
PH: 8.6
Temperature: 37
uniprot:P70500 [Mg2+]

myo_Inositol + CDP_1,2_diacylglycerol -> CMP + 1_Phosphatidyl_D_myo_inositol		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM glycylglycine, 0.5 mM dithiothreitol
PH: 8.6
Temperature: 37
uniprot:P70500 [Mg2+]

CDP_1,2_diacylglycerol + myo_Inositol -> 1_Phosphatidyl_D_myo_inositol + CMP		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM glycylglycine, 0.5 mM dithiothreitol, 0.3% Triton X-100, 10 µg P/ml asolectin
PH: 8.6
Temperature: 37
uniprot:P70500 [Mn2+]

myo_Inositol + CDP_1,2_diacylglycerol -> 1_Phosphatidyl_D_myo_inositol + CMP		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM glycylglycine, 0.3% Triton X-100
PH: 8.6
Temperature: 37
uniprot:P70500 [Mn2+]

myo_Inositol + CDP_1,2_diacylglycerol -> CMP + 1_Phosphatidyl_D_myo_inositol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM glycylglycine, 0.3% Triton X-100
PH: 8.6
Temperature: 37
- [Mn2+]

myo_Inositol + CDP_1,2_diacylglycerol -> 1_Phosphatidyl_D_myo_inositol + CMP		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM KCl
PH: 8.5
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:META_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:META_PWY-7625 phosphatidylinositol biosynthesis II (eukaryotes)
BioCyc:ARA_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:MOUSE_PWY3DJ-219 PIP metabolism
BioCyc:META_PWY-6371 superpathway of inositol phosphate compounds
BioCyc:ARA_PHOSLIPSYN2-PWY superpathway of phospholipid biosynthesis II (plants)
BioCyc:MOUSE_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:HUMAN_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis
BioCyc:YEAST_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:YEAST_PWY-7625 phosphatidylinositol biosynthesis II (eukaryotes)
BioCyc:ARA_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis
BioCyc:ARA_PWY-7625 phosphatidylinositol biosynthesis II (eukaryotes)
BioCyc:HUMAN_PWY-6371 superpathway of inositol phosphate compounds
BioCyc:META_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis
BioCyc:YEAST_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis
BioCyc:YEAST_PWY3O-242 phosphatidylinositol phosphate biosynthesis
BioCyc:MOUSE_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis
PlantCyc:ARA_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis
PlantCyc:ARA_PWY-6352 3-phosphoinositide biosynthesis
PlantCyc:ARA_PWY-7625 phosphatidylinositol biosynthesis II (eukaryotes)
PlantCyc:ARA_PHOSLIPSYN2-PWY superpathway of phospholipid biosynthesis II (plants)
Reactome:R-DME-1483206 Glycerophospholipid biosynthesis
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-1483206 Glycerophospholipid biosynthesis
Reactome:R-SPO-1483226 Synthesis of PI
Reactome:R-DME-1430728 Metabolism
Reactome:R-DME-1483257 Phospholipid metabolism
Reactome:R-DME-1483226 Synthesis of PI
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-RNO-1483206 Glycerophospholipid biosynthesis
Reactome:R-RNO-1483226 Synthesis of PI
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-1483206 Glycerophospholipid biosynthesis
Reactome:R-SCE-1483226 Synthesis of PI
Reactome:R-SPO-1483257 Phospholipid metabolism
Reactome:R-HSA-1483257 Phospholipid metabolism
Reactome:R-MMU-1483257 Phospholipid metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-556833 Metabolism of lipids
Reactome:R-SCE-556833 Metabolism of lipids
Reactome:R-DME-556833 Metabolism of lipids
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-1483206 Glycerophospholipid biosynthesis
Reactome:R-HSA-1483226 Synthesis of PI
Reactome:R-MMU-1483206 Glycerophospholipid biosynthesis
Reactome:R-MMU-1483226 Synthesis of PI
Reactome:R-RNO-1483257 Phospholipid metabolism
Reactome:R-SCE-1483257 Phospholipid metabolism
Reactome:R-SPO-556833 Metabolism of lipids
WikiPathways:WP2533 Glycerophospholipid biosynthetic pathway
PathBank:SMP0087322 Phospholipid Biosynthesis
PathBank:SMP0063652 Phospholipid Biosynthesis
PathBank:SMP0120865 Joubert Syndrome
PathBank:SMP0000463 Phosphatidylinositol Phosphate Metabolism
PathBank:SMP0012029 D-myo-Inositol (1,4,5)-Trisphosphate Biosynthesis
PathBank:SMP0063651 Phosphatidylinositol Phosphate Metabolism
PathBank:SMP0120646 Joubert Syndrome
PathBank:SMP0000025 Phospholipid Biosynthesis
PathBank:SMP0000582 Joubert Syndrome
PathBank:SMP0087351 Phosphatidylinositol Phosphate Metabolism