EC: 2.7.11.22

cyclin-dependent kinase (ATP:cyclin phosphotransferase)

enzyme lambda metabolic reaction experiment
uniprot:P17157 [Pcl10p]

Gsy2_654 + ATP -> ADP + Gsy2_654_phosphorylated
(( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM DTT, 0.1% Triton X-100, 1.25 mM MgCl2
PH: 7.4
Temperature: 30
uniprot:P17157 [Pcl10p]

Pho4_114 + ATP -> Pho4_114_phosphorylated + ADP
(( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM DTT, 0.1% Triton X-100, 1.25 mM MgCl2
PH: 7.4
Temperature: 30

Pathways

pathway id name
BioCyc:HUMAN_PWY-7434 terminal O-glycans residues modification (via type 2 precursor disaccharide)
Plant Reactome:R-OSA-9640760 G1 phase
Plant Reactome:R-OSA-9640670 Cell cycle
Plant Reactome:R-OSA-9640713 Mitosis
Plant Reactome:R-OSA-2894886 Cellular processes
Reactome:R-SSC-9616222 Transcriptional regulation of granulopoiesis
Reactome:R-RNO-9616222 Transcriptional regulation of granulopoiesis
Reactome:R-HSA-9630791 Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4
Reactome:R-HSA-9632697 Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4
Reactome:R-HSA-9616222 Transcriptional regulation of granulopoiesis
Reactome:R-HSA-9630750 Evasion of Oncogene Induced Senescence Due to p16INK4A Defects
Reactome:R-HSA-9632693 Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects
Reactome:R-DME-9616222 Transcriptional regulation of granulopoiesis
Reactome:R-MMU-9616222 Transcriptional regulation of granulopoiesis
Reactome:R-HSA-9630747 Diseases of Cellular Senescence
Reactome:R-HSA-9659787 Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects
Reactome:R-DDI-68911 G2 Phase
Reactome:R-BTA-9754119 Drug-mediated inhibition of CDK4/CDK6 activity
Reactome:R-SSC-9754119 Drug-mediated inhibition of CDK4/CDK6 activity
Reactome:R-BTA-9833482 PKR-mediated signaling
Reactome:R-HSA-9856651 MITF-M-dependent gene expression
Reactome:R-HSA-9843745 Adipogenesis
Reactome:R-HSA-9675132 Diseases of cellular response to stress
Reactome:R-CEL-68911 G2 Phase
Reactome:R-HSA-9687139 Aberrant regulation of mitotic cell cycle due to RB1 defects
Reactome:R-SPO-69656 Cyclin A:Cdk2-associated events at S phase entry
Reactome:R-DDI-75815 Ubiquitin-dependent degradation of Cyclin D
Reactome:R-MMU-9754119 Drug-mediated inhibition of CDK4/CDK6 activity
Reactome:R-CEL-9833482 PKR-mediated signaling
Reactome:R-RNO-9833482 PKR-mediated signaling
Reactome:R-CEL-9616222 Transcriptional regulation of granulopoiesis
Reactome:R-DME-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Reactome:R-DDI-9754119 Drug-mediated inhibition of CDK4/CDK6 activity
Reactome:R-RNO-9754119 Drug-mediated inhibition of CDK4/CDK6 activity
Reactome:R-CEL-9754119 Drug-mediated inhibition of CDK4/CDK6 activity
Reactome:R-HSA-9824446 Viral Infection Pathways
Reactome:R-MMU-9833482 PKR-mediated signaling
Reactome:R-CEL-69200 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Reactome:R-HSA-9675126 Diseases of mitotic cell cycle
Reactome:R-HSA-9661069 Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
Reactome:R-HSA-9754119 Drug-mediated inhibition of CDK4/CDK6 activity
Reactome:R-DME-9833482 PKR-mediated signaling
Reactome:R-HSA-9833482 PKR-mediated signaling
Reactome:R-CEL-2980767 Activation of NIMA Kinases NEK9, NEK6, NEK7
Reactome:R-HSA-9820952 Respiratory Syncytial Virus Infection Pathway
Reactome:R-HSA-9833110 RSV-host interactions
Reactome:R-HSA-9730414 MITF-M-regulated melanocyte development
Reactome:R-HSA-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Reactome:R-DME-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes
Reactome:R-HSA-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
Reactome:R-BTA-9909615 Regulation of PD-L1(CD274) Post-translational modification
Reactome:R-DDI-9909615 Regulation of PD-L1(CD274) Post-translational modification
Reactome:R-HSA-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274)
Reactome:R-SSC-9909648 Regulation of PD-L1(CD274) expression
Reactome:R-SSC-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274)
Reactome:R-DME-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Reactome:R-HSA-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes
Reactome:R-CEL-9909648 Regulation of PD-L1(CD274) expression
Reactome:R-DDI-9909648 Regulation of PD-L1(CD274) expression
Reactome:R-HSA-9909648 Regulation of PD-L1(CD274) expression
Reactome:R-MMU-9909615 Regulation of PD-L1(CD274) Post-translational modification
Reactome:R-RNO-9909615 Regulation of PD-L1(CD274) Post-translational modification
Reactome:R-DME-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
Reactome:R-HSA-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes
Reactome:R-CEL-9909615 Regulation of PD-L1(CD274) Post-translational modification
Reactome:R-DDI-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274)
Reactome:R-MMU-9909648 Regulation of PD-L1(CD274) expression
Reactome:R-MMU-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274)
Reactome:R-RNO-9909648 Regulation of PD-L1(CD274) expression
Reactome:R-RNO-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274)
Reactome:R-DME-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes
Reactome:R-HSA-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Reactome:R-BTA-9909648 Regulation of PD-L1(CD274) expression
Reactome:R-BTA-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274)
Reactome:R-CEL-389948 PD-1 signaling
Reactome:R-CEL-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274)
Reactome:R-DDI-389948 PD-1 signaling
Reactome:R-HSA-9909615 Regulation of PD-L1(CD274) Post-translational modification
Reactome:R-SSC-9909615 Regulation of PD-L1(CD274) Post-translational modification
Reactome:R-CEL-69656 Cyclin A:Cdk2-associated events at S phase entry
Reactome:R-DME-69563 p53-Dependent G1 DNA Damage Response
Reactome:R-DME-176417 Phosphorylation of Emi1
Reactome:R-DDI-69202 Cyclin E associated events during G1/S transition
Reactome:R-CEL-2559586 DNA Damage/Telomere Stress Induced Senescence
Reactome:R-CEL-69563 p53-Dependent G1 DNA Damage Response
Reactome:R-CEL-187577 SCF(Skp2)-mediated degradation of p27/p21
Reactome:R-CEL-3301854 Nuclear Pore Complex (NPC) Disassembly
Reactome:R-SPO-2559582 Senescence-Associated Secretory Phenotype (SASP)
Reactome:R-DME-69580 p53-Dependent G1/S DNA damage checkpoint
Reactome:R-DDI-69656 Cyclin A:Cdk2-associated events at S phase entry
Reactome:R-CEL-112382 Formation of RNA Pol II elongation complex
Reactome:R-DDI-69017 CDK-mediated phosphorylation and removal of Cdc6
Reactome:R-DDI-187577 SCF(Skp2)-mediated degradation of p27/p21
Reactome:R-CEL-69580 p53-Dependent G1/S DNA damage checkpoint
Reactome:R-CEL-69202 Cyclin E associated events during G1/S transition
Reactome:R-SPO-69202 Cyclin E associated events during G1/S transition
Reactome:R-DDI-69200 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Reactome:R-BTA-597592 Post-translational protein modification
Reactome:R-BTA-5689896 Ovarian tumor domain proteases
Reactome:R-BTA-74160 Gene expression (Transcription)
Reactome:R-BTA-73857 RNA Polymerase II Transcription
Reactome:R-BTA-3700989 Transcriptional Regulation by TP53
Reactome:R-BTA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Reactome:R-BTA-5633007 Regulation of TP53 Activity
Reactome:R-BTA-6804756 Regulation of TP53 Activity through Phosphorylation
Reactome:R-BTA-1640170 Cell Cycle
Reactome:R-BTA-69563 p53-Dependent G1 DNA Damage Response
Reactome:R-BTA-69481 G2/M Checkpoints
Reactome:R-BTA-1538133 G0 and Early G1
Reactome:R-BTA-69202 Cyclin E associated events during G1/S transition
Reactome:R-BTA-69239 Synthesis of DNA
Reactome:R-BTA-69017 CDK-mediated phosphorylation and removal of Cdc6
Reactome:R-BTA-75815 Ubiquitin-dependent degradation of Cyclin D
Reactome:R-BTA-68911 G2 Phase
Reactome:R-BTA-380259 Loss of Nlp from mitotic centrosomes
Reactome:R-BTA-2299718 Condensation of Prophase Chromosomes
Reactome:R-BTA-3301854 Nuclear Pore Complex (NPC) Disassembly
Reactome:R-BTA-2500257 Resolution of Sister Chromatid Cohesion
Reactome:R-BTA-2995383 Initiation of Nuclear Envelope (NE) Reformation
Reactome:R-BTA-174143 APC/C-mediated degradation of cell cycle proteins
Reactome:R-BTA-176412 Phosphorylation of the APC/C
Reactome:R-BTA-168256 Immune System
Reactome:R-BTA-389948 PD-1 signaling
Reactome:R-BTA-168898 Toll-like Receptor Cascades
Reactome:R-BTA-198753 ERK/MAPK targets
Reactome:R-BTA-168164 Toll Like Receptor 3 (TLR3) Cascade
Reactome:R-BTA-975155 MyD88 dependent cascade initiated on endosome
Reactome:R-BTA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane
Reactome:R-BTA-168179 Toll Like Receptor TLR1:TLR2 Cascade
Reactome:R-BTA-913531 Interferon Signaling
Reactome:R-BTA-449147 Signaling by Interleukins
Reactome:R-BTA-448424 Interleukin-17 signaling
Reactome:R-BTA-5693532 DNA Double-Strand Break Repair
Reactome:R-BTA-5693538 Homology Directed Repair
Reactome:R-BTA-8953897 Cellular responses to stimuli
Reactome:R-BTA-2262752 Cellular responses to stress
Reactome:R-BTA-2559583 Cellular Senescence
Reactome:R-BTA-9006934 Signaling by Receptor Tyrosine Kinases
Reactome:R-BTA-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-BTA-8939211 ESR-mediated signaling
Reactome:R-CEL-453279 Mitotic G1 phase and G1/S transition
Reactome:R-CEL-69206 G1/S Transition
Reactome:R-CEL-69242 S Phase
Reactome:R-CEL-68949 Orc1 removal from chromatin
Reactome:R-CEL-75815 Ubiquitin-dependent degradation of Cyclin D
Reactome:R-CEL-69273 Cyclin A/B1/B2 associated events during G2/M transition
Reactome:R-CEL-68875 Mitotic Prophase
Reactome:R-CEL-4419969 Depolymerization of the Nuclear Lamina
Reactome:R-CEL-176408 Regulation of APC/C activators between G1/S and early anaphase
Reactome:R-CEL-1280218 Adaptive Immune System
Reactome:R-CEL-388841 Costimulation by the CD28 family
Reactome:R-CEL-73894 DNA Repair
Reactome:R-CEL-5696395 Formation of Incision Complex in GG-NER
Reactome:R-CEL-8953897 Cellular responses to stimuli
Reactome:R-CEL-9006936 Signaling by TGFB family members
Reactome:R-CEL-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Reactome:R-CEL-5683057 MAPK family signaling cascades
Reactome:R-CEL-112409 RAF-independent MAPK1/3 activation
Reactome:R-CEL-3700989 Transcriptional Regulation by TP53
Reactome:R-CEL-6791312 TP53 Regulates Transcription of Cell Cycle Genes
Reactome:R-CEL-113418 Formation of the Early Elongation Complex
Reactome:R-DRE-75955 RNA Polymerase II Transcription Elongation
Reactome:R-DDI-73894 DNA Repair
Reactome:R-DDI-5696399 Global Genome Nucleotide Excision Repair (GG-NER)
Reactome:R-DDI-6781823 Formation of TC-NER Pre-Incision Complex
Reactome:R-DDI-69002 DNA Replication Pre-Initiation
Reactome:R-DDI-69239 Synthesis of DNA
Reactome:R-DDI-3247509 Chromatin modifying enzymes
Reactome:R-DDI-3214858 RMTs methylate histone arginines
Reactome:R-DDI-2559582 Senescence-Associated Secretory Phenotype (SASP)
Reactome:R-DDI-1538133 G0 and Early G1
Reactome:R-DDI-453274 Mitotic G2-G2/M phases
Reactome:R-DDI-453276 Regulation of mitotic cell cycle
Reactome:R-DDI-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance
Reactome:R-DDI-75955 RNA Polymerase II Transcription Elongation
Reactome:R-DDI-168256 Immune System
Reactome:R-DDI-388841 Costimulation by the CD28 family
Reactome:R-DME-69239 Synthesis of DNA
Reactome:R-DME-69017 CDK-mediated phosphorylation and removal of Cdc6
Reactome:R-DME-168256 Immune System
Reactome:R-DME-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-DME-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-DME-2559583 Cellular Senescence
Reactome:R-DME-2559582 Senescence-Associated Secretory Phenotype (SASP)
Reactome:R-DME-69615 G1/S DNA Damage Checkpoints
Reactome:R-DME-69481 G2/M Checkpoints
Reactome:R-DME-69278 Cell Cycle, Mitotic
Reactome:R-DME-69231 Cyclin D associated events in G1
Reactome:R-DME-69200 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Reactome:R-DME-69656 Cyclin A:Cdk2-associated events at S phase entry
Reactome:R-DME-453274 Mitotic G2-G2/M phases
Reactome:R-DME-2565942 Regulation of PLK1 Activity at G2/M Transition
Reactome:R-DME-68875 Mitotic Prophase
Reactome:R-DME-3301854 Nuclear Pore Complex (NPC) Disassembly
Reactome:R-DME-2995410 Nuclear Envelope (NE) Reassembly
Reactome:R-DME-453276 Regulation of mitotic cell cycle
Reactome:R-DME-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome:R-DME-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Reactome:R-DME-1266738 Developmental Biology
Reactome:R-DME-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
Reactome:R-GGA-351470 Homologous recombination repair of replication-independent double-strand breaks
Reactome:R-HSA-5620912 Anchoring of the basal body to the plasma membrane
Reactome:R-HSA-1474165 Reproduction
Reactome:R-HSA-912446 Meiotic recombination
Reactome:R-HSA-400206 Regulation of lipid metabolism by PPARalpha
Reactome:R-HSA-5693532 DNA Double-Strand Break Repair
Reactome:R-HSA-5693538 Homology Directed Repair
Reactome:R-HSA-5696398 Nucleotide Excision Repair
Reactome:R-HSA-9006936 Signaling by TGFB family members
Reactome:R-HSA-157118 Signaling by NOTCH
Reactome:R-HSA-5683057 MAPK family signaling cascades
Reactome:R-HSA-112409 RAF-independent MAPK1/3 activation
Reactome:R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP)
Reactome:R-HSA-69620 Cell Cycle Checkpoints
Reactome:R-HSA-69473 G2/M DNA damage checkpoint
Reactome:R-HSA-69206 G1/S Transition
Reactome:R-HSA-69205 G1/S-Specific Transcription
Reactome:R-HSA-69239 Synthesis of DNA
Reactome:R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6
Reactome:R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D
Reactome:R-HSA-68911 G2 Phase
Reactome:R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition
Reactome:R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome
Reactome:R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization
Reactome:R-HSA-2980767 Activation of NIMA Kinases NEK9, NEK6, NEK7
Reactome:R-HSA-68877 Mitotic Prometaphase
Reactome:R-HSA-2555396 Mitotic Metaphase and Anaphase
Reactome:R-HSA-2995410 Nuclear Envelope (NE) Reassembly
Reactome:R-HSA-453276 Regulation of mitotic cell cycle
Reactome:R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Reactome:R-HSA-73886 Chromosome Maintenance
Reactome:R-HSA-180786 Extension of Telomeres
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-597592 Post-translational protein modification
Reactome:R-HSA-5689896 Ovarian tumor domain proteases
Reactome:R-HSA-1643685 Disease
Reactome:R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants
Reactome:R-HSA-162587 HIV Life Cycle
Reactome:R-HSA-167172 Transcription of the HIV genome
Reactome:R-HSA-167169 HIV Transcription Elongation
Reactome:R-HSA-162909 Host Interactions of HIV factors
Reactome:R-HSA-176034 Interactions of Tat with host cellular proteins
Reactome:R-HSA-69002 DNA Replication Pre-Initiation
Reactome:R-HSA-74160 Gene expression (Transcription)
Reactome:R-HSA-73762 RNA Polymerase I Transcription Initiation
Reactome:R-HSA-73857 RNA Polymerase II Transcription
Reactome:R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes
Reactome:R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes
Reactome:R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance
Reactome:R-HSA-75955 RNA Polymerase II Transcription Elongation
Reactome:R-HSA-388841 Costimulation by the CD28 family
Reactome:R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade
Reactome:R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade
Reactome:R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade
Reactome:R-HSA-937061 TRIF (TICAM1)-mediated TLR4 signaling
Reactome:R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes
Reactome:R-HSA-448424 Interleukin-17 signaling
Reactome:R-MMU-1640170 Cell Cycle
Reactome:R-MMU-69563 p53-Dependent G1 DNA Damage Response
Reactome:R-MMU-69481 G2/M Checkpoints
Reactome:R-MMU-1538133 G0 and Early G1
Reactome:R-MMU-69202 Cyclin E associated events during G1/S transition
Reactome:R-MMU-69239 Synthesis of DNA
Reactome:R-MMU-69017 CDK-mediated phosphorylation and removal of Cdc6
Reactome:R-MMU-75815 Ubiquitin-dependent degradation of Cyclin D
Reactome:R-MMU-68911 G2 Phase
Reactome:R-MMU-380259 Loss of Nlp from mitotic centrosomes
Reactome:R-MMU-2299718 Condensation of Prophase Chromosomes
Reactome:R-MMU-3301854 Nuclear Pore Complex (NPC) Disassembly
Reactome:R-MMU-68882 Mitotic Anaphase
Reactome:R-MMU-176408 Regulation of APC/C activators between G1/S and early anaphase
Reactome:R-MMU-176412 Phosphorylation of the APC/C
Reactome:R-MMU-168256 Immune System
Reactome:R-MMU-389948 PD-1 signaling
Reactome:R-MMU-168249 Innate Immune System
Reactome:R-MMU-975871 MyD88 cascade initiated on plasma membrane
Reactome:R-MMU-450294 MAP kinase activation
Reactome:R-MMU-450282 MAPK targets/ Nuclear events mediated by MAP kinases
Reactome:R-MMU-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade
Reactome:R-MMU-181438 Toll Like Receptor 2 (TLR2) Cascade
Reactome:R-MMU-913531 Interferon Signaling
Reactome:R-MMU-449147 Signaling by Interleukins
Reactome:R-MMU-448424 Interleukin-17 signaling
Reactome:R-MMU-5693607 Processing of DNA double-strand break ends
Reactome:R-MMU-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Reactome:R-MMU-8953854 Metabolism of RNA
Reactome:R-MMU-3214858 RMTs methylate histone arginines
Reactome:R-MMU-74160 Gene expression (Transcription)
Reactome:R-MMU-73762 RNA Polymerase I Transcription Initiation
Reactome:R-MMU-73857 RNA Polymerase II Transcription
Reactome:R-MMU-3700989 Transcriptional Regulation by TP53
Reactome:R-MMU-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Reactome:R-MMU-5633007 Regulation of TP53 Activity
Reactome:R-MMU-6804756 Regulation of TP53 Activity through Phosphorylation
Reactome:R-MMU-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs
Reactome:R-MMU-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
Reactome:R-MMU-162582 Signaling Pathways
Reactome:R-MMU-166520 Signaling by NTRKs
Reactome:R-MMU-8939211 ESR-mediated signaling
Reactome:R-RNO-5620912 Anchoring of the basal body to the plasma membrane
Reactome:R-RNO-69620 Cell Cycle Checkpoints
Reactome:R-RNO-69473 G2/M DNA damage checkpoint
Reactome:R-RNO-69236 G1 Phase
Reactome:R-RNO-187577 SCF(Skp2)-mediated degradation of p27/p21
Reactome:R-RNO-69275 G2/M Transition
Reactome:R-RNO-380287 Centrosome maturation
Reactome:R-RNO-68886 M Phase
Reactome:R-RNO-4419969 Depolymerization of the Nuclear Lamina
Reactome:R-RNO-380320 Recruitment of NuMA to mitotic centrosomes
Reactome:R-RNO-176417 Phosphorylation of Emi1
Reactome:R-RNO-176409 APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome:R-RNO-174048 APC/C:Cdc20 mediated degradation of Cyclin B
Reactome:R-RNO-157579 Telomere Maintenance
Reactome:R-RNO-597592 Post-translational protein modification
Reactome:R-RNO-5689896 Ovarian tumor domain proteases
Reactome:R-RNO-69002 DNA Replication Pre-Initiation
Reactome:R-RNO-6791312 TP53 Regulates Transcription of Cell Cycle Genes
Reactome:R-RNO-6796648 TP53 Regulates Transcription of DNA Repair Genes
Reactome:R-RNO-8878171 Transcriptional regulation by RUNX1
Reactome:R-RNO-113418 Formation of the Early Elongation Complex
Reactome:R-RNO-6807505 RNA polymerase II transcribes snRNA genes
Reactome:R-RNO-2559582 Senescence-Associated Secretory Phenotype (SASP)
Reactome:R-RNO-162582 Signaling Pathways
Reactome:R-RNO-9006936 Signaling by TGFB family members
Reactome:R-RNO-9006931 Signaling by Nuclear Receptors
Reactome:R-RNO-9018519 Estrogen-dependent gene expression
Reactome:R-RNO-5687128 MAPK6/MAPK4 signaling
Reactome:R-RNO-73894 DNA Repair
Reactome:R-RNO-5696395 Formation of Incision Complex in GG-NER
Reactome:R-RNO-6781823 Formation of TC-NER Pre-Incision Complex
Reactome:R-RNO-1280218 Adaptive Immune System
Reactome:R-RNO-1169410 Antiviral mechanism by IFN-stimulated genes
Reactome:R-RNO-1266738 Developmental Biology
Reactome:R-SCE-1640170 Cell Cycle
Reactome:R-SCE-69206 G1/S Transition
Reactome:R-SPO-69002 DNA Replication Pre-Initiation
Reactome:R-SPO-68962 Activation of the pre-replicative complex
Reactome:R-SPO-68949 Orc1 removal from chromatin
Reactome:R-SPO-69206 G1/S Transition
Reactome:R-SPO-176408 Regulation of APC/C activators between G1/S and early anaphase
Reactome:R-SSC-3247509 Chromatin modifying enzymes
Reactome:R-SSC-69278 Cell Cycle, Mitotic
Reactome:R-SSC-69231 Cyclin D associated events in G1
Reactome:R-SSC-69242 S Phase
Reactome:R-SSC-168256 Immune System
Reactome:R-SSC-389948 PD-1 signaling
Reactome:R-XTR-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-BTA-6791312 TP53 Regulates Transcription of Cell Cycle Genes
Reactome:R-BTA-6796648 TP53 Regulates Transcription of DNA Repair Genes
Reactome:R-BTA-674695 RNA Polymerase II Pre-transcription Events
Reactome:R-BTA-112382 Formation of RNA Pol II elongation complex
Reactome:R-BTA-69580 p53-Dependent G1/S DNA damage checkpoint
Reactome:R-BTA-69478 G2/M DNA replication checkpoint
Reactome:R-BTA-453279 Mitotic G1 phase and G1/S transition
Reactome:R-BTA-69206 G1/S Transition
Reactome:R-BTA-68962 Activation of the pre-replicative complex
Reactome:R-BTA-69656 Cyclin A:Cdk2-associated events at S phase entry
Reactome:R-BTA-68949 Orc1 removal from chromatin
Reactome:R-BTA-453274 Mitotic G2-G2/M phases
Reactome:R-BTA-2565942 Regulation of PLK1 Activity at G2/M Transition
Reactome:R-BTA-380284 Loss of proteins required for interphase microtubule organization from the centrosome
Reactome:R-BTA-2980767 Activation of NIMA Kinases NEK9, NEK6, NEK7
Reactome:R-BTA-68877 Mitotic Prometaphase
Reactome:R-BTA-2555396 Mitotic Metaphase and Anaphase
Reactome:R-BTA-2995410 Nuclear Envelope (NE) Reassembly
Reactome:R-BTA-453276 Regulation of mitotic cell cycle
Reactome:R-BTA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome:R-BTA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Reactome:R-BTA-171319 Telomere Extension By Telomerase
Reactome:R-BTA-3214858 RMTs methylate histone arginines
Reactome:R-BTA-388841 Costimulation by the CD28 family
Reactome:R-BTA-168249 Innate Immune System
Reactome:R-BTA-975871 MyD88 cascade initiated on plasma membrane
Reactome:R-BTA-450294 MAP kinase activation
Reactome:R-BTA-450282 MAPK targets/ Nuclear events mediated by MAP kinases
Reactome:R-BTA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade
Reactome:R-BTA-181438 Toll Like Receptor 2 (TLR2) Cascade
Reactome:R-BTA-1280215 Cytokine Signaling in Immune system
Reactome:R-BTA-73894 DNA Repair
Reactome:R-BTA-2559586 DNA Damage/Telomere Stress Induced Senescence
Reactome:R-BTA-5620912 Anchoring of the basal body to the plasma membrane
Reactome:R-BTA-69002 DNA Replication Pre-Initiation
Reactome:R-BTA-162582 Signaling Pathways
Reactome:R-BTA-9006936 Signaling by TGFB family members
Reactome:R-BTA-5684996 ERK1/ERK2 pathway
Reactome:R-BTA-110056 MAPK3 (ERK1) activation
Reactome:R-CEL-69615 G1/S DNA Damage Checkpoints
Reactome:R-CEL-69481 G2/M Checkpoints
Reactome:R-CEL-69278 Cell Cycle, Mitotic
Reactome:R-CEL-69231 Cyclin D associated events in G1
Reactome:R-CEL-69052 Switching of origins to a post-replicative state
Reactome:R-CEL-69275 G2/M Transition
Reactome:R-CEL-68886 M Phase
Reactome:R-CEL-2980766 Nuclear Envelope Breakdown
Reactome:R-CEL-174143 APC/C-mediated degradation of cell cycle proteins
Reactome:R-CEL-168256 Immune System
Reactome:R-CEL-913531 Interferon Signaling
Reactome:R-CEL-1169410 Antiviral mechanism by IFN-stimulated genes
Reactome:R-CEL-69306 DNA Replication
Reactome:R-CEL-72086 mRNA Capping
Reactome:R-CEL-6781823 Formation of TC-NER Pre-Incision Complex
Reactome:R-CEL-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-CEL-1266738 Developmental Biology
Reactome:R-CEL-3247509 Chromatin modifying enzymes
Reactome:R-CEL-3214858 RMTs methylate histone arginines
Reactome:R-CEL-212436 Generic Transcription Pathway
Reactome:R-CEL-6796648 TP53 Regulates Transcription of DNA Repair Genes
Reactome:R-CEL-8934593 Regulation of RUNX1 Expression and Activity
Reactome:R-CEL-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance
Reactome:R-CEL-75955 RNA Polymerase II Transcription Elongation
Reactome:R-CEL-6807505 RNA polymerase II transcribes snRNA genes
Reactome:R-DRE-6807505 RNA polymerase II transcribes snRNA genes
Reactome:R-DDI-5696398 Nucleotide Excision Repair
Reactome:R-DDI-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Reactome:R-DDI-69306 DNA Replication
Reactome:R-DDI-68962 Activation of the pre-replicative complex
Reactome:R-DDI-68949 Orc1 removal from chromatin
Reactome:R-DDI-4839726 Chromatin organization
Reactome:R-DDI-2262752 Cellular responses to stress
Reactome:R-DDI-453279 Mitotic G1 phase and G1/S transition
Reactome:R-DDI-69206 G1/S Transition
Reactome:R-DDI-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
Reactome:R-DME-68962 Activation of the pre-replicative complex
Reactome:R-DME-68949 Orc1 removal from chromatin
Reactome:R-DME-913531 Interferon Signaling
Reactome:R-DME-1169410 Antiviral mechanism by IFN-stimulated genes
Reactome:R-DME-162582 Signaling Pathways
Reactome:R-DME-9006936 Signaling by TGFB family members
Reactome:R-DME-8953897 Cellular responses to stimuli
Reactome:R-DME-2559586 DNA Damage/Telomere Stress Induced Senescence
Reactome:R-DME-69620 Cell Cycle Checkpoints
Reactome:R-DME-69478 G2/M DNA replication checkpoint
Reactome:R-DME-69236 G1 Phase
Reactome:R-DME-187577 SCF(Skp2)-mediated degradation of p27/p21
Reactome:R-DME-69242 S Phase
Reactome:R-DME-69273 Cyclin A/B1/B2 associated events during G2/M transition
Reactome:R-DME-68886 M Phase
Reactome:R-DME-2980766 Nuclear Envelope Breakdown
Reactome:R-DME-2500257 Resolution of Sister Chromatid Cohesion
Reactome:R-DME-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Reactome:R-DME-73894 DNA Repair
Reactome:R-DME-5693532 DNA Double-Strand Break Repair
Reactome:R-DME-5693538 Homology Directed Repair
Reactome:R-DME-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Reactome:R-DME-6804756 Regulation of TP53 Activity through Phosphorylation
Reactome:R-DME-8878166 Transcriptional regulation by RUNX2
Reactome:R-GGA-351451 Homologous recombination repair of replication-dependent DSB
Reactome:R-HSA-5617833 Cilium Assembly
Reactome:R-HSA-1266738 Developmental Biology
Reactome:R-HSA-1500620 Meiosis
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-5696395 Formation of Incision Complex in GG-NER
Reactome:R-HSA-6781823 Formation of TC-NER Pre-Incision Complex
Reactome:R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
Reactome:R-HSA-202670 ERKs are inactivated
Reactome:R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription
Reactome:R-HSA-9006931 Signaling by Nuclear Receptors
Reactome:R-HSA-9018519 Estrogen-dependent gene expression
Reactome:R-HSA-5687128 MAPK6/MAPK4 signaling
Reactome:R-HSA-2262752 Cellular responses to stress
Reactome:R-HSA-2559583 Cellular Senescence
Reactome:R-HSA-1640170 Cell Cycle
Reactome:R-HSA-69563 p53-Dependent G1 DNA Damage Response
Reactome:R-HSA-69481 G2/M Checkpoints
Reactome:R-HSA-1538133 G0 and Early G1
Reactome:R-HSA-69231 Cyclin D associated events in G1
Reactome:R-HSA-69200 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Reactome:R-HSA-113510 E2F mediated regulation of DNA replication
Reactome:R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry
Reactome:R-HSA-68949 Orc1 removal from chromatin
Reactome:R-HSA-453274 Mitotic G2-G2/M phases
Reactome:R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes
Reactome:R-HSA-8854518 AURKA Activation by TPX2
Reactome:R-HSA-68875 Mitotic Prophase
Reactome:R-HSA-2980766 Nuclear Envelope Breakdown
Reactome:R-HSA-4419969 Depolymerization of the Nuclear Lamina
Reactome:R-HSA-380320 Recruitment of NuMA to mitotic centrosomes
Reactome:R-HSA-176417 Phosphorylation of Emi1
Reactome:R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome:R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B
Reactome:R-HSA-157579 Telomere Maintenance
Reactome:R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer
Reactome:R-HSA-162906 HIV Infection
Reactome:R-HSA-162599 Late Phase of HIV Life Cycle
Reactome:R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat
Reactome:R-HSA-167290 Pausing and recovery of HIV elongation
Reactome:R-HSA-69306 DNA Replication
Reactome:R-HSA-3214858 RMTs methylate histone arginines
Reactome:R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs
Reactome:R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
Reactome:R-HSA-212165 Epigenetic regulation of gene expression
Reactome:R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade
Reactome:R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Reactome:R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade
Reactome:R-HSA-166166 MyD88-independent TLR4 cascade
Reactome:R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade
Reactome:R-HSA-913531 Interferon Signaling
Reactome:R-HSA-449147 Signaling by Interleukins
Reactome:R-MMU-69580 p53-Dependent G1/S DNA damage checkpoint
Reactome:R-MMU-69478 G2/M DNA replication checkpoint
Reactome:R-MMU-453279 Mitotic G1 phase and G1/S transition
Reactome:R-MMU-69206 G1/S Transition
Reactome:R-MMU-68962 Activation of the pre-replicative complex
Reactome:R-MMU-69656 Cyclin A:Cdk2-associated events at S phase entry
Reactome:R-MMU-68949 Orc1 removal from chromatin
Reactome:R-MMU-453274 Mitotic G2-G2/M phases
Reactome:R-MMU-2565942 Regulation of PLK1 Activity at G2/M Transition
Reactome:R-MMU-380284 Loss of proteins required for interphase microtubule organization from the centrosome
Reactome:R-MMU-2980767 Activation of NIMA Kinases NEK9, NEK6, NEK7
Reactome:R-MMU-2500257 Resolution of Sister Chromatid Cohesion
Reactome:R-MMU-2995383 Initiation of Nuclear Envelope (NE) Reformation
Reactome:R-MMU-174143 APC/C-mediated degradation of cell cycle proteins
Reactome:R-MMU-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome:R-MMU-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Reactome:R-MMU-171319 Telomere Extension By Telomerase
Reactome:R-MMU-69002 DNA Replication Pre-Initiation
Reactome:R-MMU-388841 Costimulation by the CD28 family
Reactome:R-MMU-168142 Toll Like Receptor 10 (TLR10) Cascade
Reactome:R-MMU-168176 Toll Like Receptor 5 (TLR5) Cascade
Reactome:R-MMU-166016 Toll Like Receptor 4 (TLR4) Cascade
Reactome:R-MMU-937061 TRIF (TICAM1)-mediated TLR4 signaling
Reactome:R-MMU-1280215 Cytokine Signaling in Immune system
Reactome:R-MMU-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
Reactome:R-MMU-5696399 Global Genome Nucleotide Excision Repair (GG-NER)
Reactome:R-MMU-2559582 Senescence-Associated Secretory Phenotype (SASP)
Reactome:R-MMU-3247509 Chromatin modifying enzymes
Reactome:R-MMU-6791312 TP53 Regulates Transcription of Cell Cycle Genes
Reactome:R-MMU-6796648 TP53 Regulates Transcription of DNA Repair Genes
Reactome:R-MMU-8934593 Regulation of RUNX1 Expression and Activity
Reactome:R-MMU-674695 RNA Polymerase II Pre-transcription Events
Reactome:R-MMU-73776 RNA Polymerase II Promoter Escape
Reactome:R-MMU-112382 Formation of RNA Pol II elongation complex
Reactome:R-MMU-187037 Signaling by NTRK1 (TRKA)
Reactome:R-MMU-198725 Nuclear Events (kinase and transcription factor activation)
Reactome:R-MMU-5684996 ERK1/ERK2 pathway
Reactome:R-MMU-110056 MAPK3 (ERK1) activation
Reactome:R-RNO-1852241 Organelle biogenesis and maintenance
Reactome:R-RNO-5617833 Cilium Assembly
Reactome:R-RNO-72086 mRNA Capping
Reactome:R-RNO-1640170 Cell Cycle
Reactome:R-RNO-69563 p53-Dependent G1 DNA Damage Response
Reactome:R-RNO-69481 G2/M Checkpoints
Reactome:R-RNO-1538133 G0 and Early G1
Reactome:R-RNO-69202 Cyclin E associated events during G1/S transition
Reactome:R-RNO-69239 Synthesis of DNA
Reactome:R-RNO-69017 CDK-mediated phosphorylation and removal of Cdc6
Reactome:R-RNO-75815 Ubiquitin-dependent degradation of Cyclin D
Reactome:R-RNO-68911 G2 Phase
Reactome:R-RNO-380259 Loss of Nlp from mitotic centrosomes
Reactome:R-RNO-2299718 Condensation of Prophase Chromosomes
Reactome:R-RNO-3301854 Nuclear Pore Complex (NPC) Disassembly
Reactome:R-RNO-68882 Mitotic Anaphase
Reactome:R-RNO-176408 Regulation of APC/C activators between G1/S and early anaphase
Reactome:R-RNO-176412 Phosphorylation of the APC/C
Reactome:R-RNO-392499 Metabolism of proteins
Reactome:R-RNO-69306 DNA Replication
Reactome:R-RNO-73854 RNA Polymerase I Promoter Clearance
Reactome:R-RNO-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Reactome:R-RNO-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance
Reactome:R-RNO-75955 RNA Polymerase II Transcription Elongation
Reactome:R-RNO-8953897 Cellular responses to stimuli
Reactome:R-RNO-2262752 Cellular responses to stress
Reactome:R-RNO-2559583 Cellular Senescence
Reactome:R-RNO-8939211 ESR-mediated signaling
Reactome:R-RNO-5693607 Processing of DNA double-strand break ends
Reactome:R-RNO-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Reactome:R-RNO-168256 Immune System
Reactome:R-RNO-389948 PD-1 signaling
Reactome:R-RNO-913531 Interferon Signaling
Reactome:R-SCE-453279 Mitotic G1 phase and G1/S transition
Reactome:R-SCE-68962 Activation of the pre-replicative complex
Reactome:R-SCE-69002 DNA Replication Pre-Initiation
Reactome:R-SPO-69306 DNA Replication
Reactome:R-SPO-69052 Switching of origins to a post-replicative state
Reactome:R-SPO-1640170 Cell Cycle
Reactome:R-SPO-453279 Mitotic G1 phase and G1/S transition
Reactome:R-SPO-69242 S Phase
Reactome:R-SPO-174143 APC/C-mediated degradation of cell cycle proteins
Reactome:R-SPO-2262752 Cellular responses to stress
Reactome:R-SSC-4839726 Chromatin organization
Reactome:R-SSC-212436 Generic Transcription Pathway
Reactome:R-SSC-8878166 Transcriptional regulation by RUNX2
Reactome:R-SSC-69236 G1 Phase
Reactome:R-SSC-388841 Costimulation by the CD28 family
Reactome:R-XTR-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Reactome:R-XTR-6796648 TP53 Regulates Transcription of DNA Repair Genes
Reactome:R-XTR-674695 RNA Polymerase II Pre-transcription Events
Reactome:R-XTR-112382 Formation of RNA Pol II elongation complex
Reactome:R-XTR-9006936 Signaling by TGFB family members
Reactome:R-XTR-9006931 Signaling by Nuclear Receptors
Reactome:R-XTR-9018519 Estrogen-dependent gene expression
Reactome:R-BTA-392499 Metabolism of proteins
Reactome:R-BTA-5688426 Deubiquitination
Reactome:R-BTA-212436 Generic Transcription Pathway
Reactome:R-BTA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-BTA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Reactome:R-BTA-8878166 Transcriptional regulation by RUNX2
Reactome:R-BTA-75955 RNA Polymerase II Transcription Elongation
Reactome:R-BTA-69620 Cell Cycle Checkpoints
Reactome:R-BTA-69473 G2/M DNA damage checkpoint
Reactome:R-BTA-69236 G1 Phase
Reactome:R-BTA-187577 SCF(Skp2)-mediated degradation of p27/p21
Reactome:R-BTA-69275 G2/M Transition
Reactome:R-BTA-380287 Centrosome maturation
Reactome:R-BTA-68886 M Phase
Reactome:R-BTA-68882 Mitotic Anaphase
Reactome:R-BTA-176408 Regulation of APC/C activators between G1/S and early anaphase
Reactome:R-BTA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome:R-BTA-174048 APC/C:Cdc20 mediated degradation of Cyclin B
Reactome:R-BTA-157579 Telomere Maintenance
Reactome:R-BTA-4839726 Chromatin organization
Reactome:R-BTA-1280218 Adaptive Immune System
Reactome:R-BTA-202670 ERKs are inactivated
Reactome:R-BTA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Reactome:R-BTA-168138 Toll Like Receptor 9 (TLR9) Cascade
Reactome:R-BTA-166166 MyD88-independent TLR4 cascade
Reactome:R-BTA-168188 Toll Like Receptor TLR6:TLR2 Cascade
Reactome:R-BTA-1169410 Antiviral mechanism by IFN-stimulated genes
Reactome:R-BTA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
Reactome:R-BTA-2559582 Senescence-Associated Secretory Phenotype (SASP)
Reactome:R-BTA-187037 Signaling by NTRK1 (TRKA)
Reactome:R-BTA-198725 Nuclear Events (kinase and transcription factor activation)
Reactome:R-BTA-9006931 Signaling by Nuclear Receptors
Reactome:R-BTA-9018519 Estrogen-dependent gene expression
Reactome:R-BTA-5687128 MAPK6/MAPK4 signaling
Reactome:R-CEL-1640170 Cell Cycle
Reactome:R-CEL-1538133 G0 and Early G1
Reactome:R-CEL-69239 Synthesis of DNA
Reactome:R-CEL-69017 CDK-mediated phosphorylation and removal of Cdc6
Reactome:R-CEL-2565942 Regulation of PLK1 Activity at G2/M Transition
Reactome:R-CEL-68877 Mitotic Prometaphase
Reactome:R-CEL-5696398 Nucleotide Excision Repair
Reactome:R-CEL-2559583 Cellular Senescence
Reactome:R-CEL-162582 Signaling Pathways
Reactome:R-CEL-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-CEL-5684996 ERK1/ERK2 pathway
Reactome:R-CEL-110056 MAPK3 (ERK1) activation
Reactome:R-CEL-74160 Gene expression (Transcription)
Reactome:R-CEL-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Reactome:R-CEL-8878166 Transcriptional regulation by RUNX2
Reactome:R-CEL-674695 RNA Polymerase II Pre-transcription Events
Reactome:R-CEL-73776 RNA Polymerase II Promoter Escape
Reactome:R-DDI-8953897 Cellular responses to stimuli
Reactome:R-DDI-1640170 Cell Cycle
Reactome:R-DDI-69236 G1 Phase
Reactome:R-DDI-174143 APC/C-mediated degradation of cell cycle proteins
Reactome:R-DDI-74160 Gene expression (Transcription)
Reactome:R-DDI-73857 RNA Polymerase II Transcription
Reactome:R-DDI-113418 Formation of the Early Elongation Complex
Reactome:R-DDI-8953854 Metabolism of RNA
Reactome:R-DDI-1280218 Adaptive Immune System
Reactome:R-DME-69306 DNA Replication
Reactome:R-DME-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Reactome:R-DME-5683057 MAPK family signaling cascades
Reactome:R-DME-112409 RAF-independent MAPK1/3 activation
Reactome:R-DME-2262752 Cellular responses to stress
Reactome:R-DME-69473 G2/M DNA damage checkpoint
Reactome:R-DME-453279 Mitotic G1 phase and G1/S transition
Reactome:R-DME-69206 G1/S Transition
Reactome:R-DME-68911 G2 Phase
Reactome:R-DME-4419969 Depolymerization of the Nuclear Lamina
Reactome:R-DME-2555396 Mitotic Metaphase and Anaphase
Reactome:R-DME-2995383 Initiation of Nuclear Envelope (NE) Reformation
Reactome:R-DME-174143 APC/C-mediated degradation of cell cycle proteins
Reactome:R-DME-176412 Phosphorylation of the APC/C
Reactome:R-DME-5693607 Processing of DNA double-strand break ends
Reactome:R-DME-74160 Gene expression (Transcription)
Reactome:R-DME-73857 RNA Polymerase II Transcription
Reactome:R-DME-3700989 Transcriptional Regulation by TP53
Reactome:R-DME-6796648 TP53 Regulates Transcription of DNA Repair Genes
Reactome:R-DME-212165 Epigenetic regulation of gene expression
Reactome:R-GGA-1670466 DNA replication and repair
Reactome:R-GGA-353371 Double strand break repair
Reactome:R-GGA-265976 Homologous DNA pairing and strand exchange
Reactome:R-HSA-381340 Transcriptional regulation of white adipocyte differentiation
Reactome:R-HSA-109582 Hemostasis
Reactome:R-HSA-1989781 PPARA activates gene expression
Reactome:R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
Reactome:R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER)
Reactome:R-HSA-187037 Signaling by NTRK1 (TRKA)
Reactome:R-HSA-198725 Nuclear Events (kinase and transcription factor activation)
Reactome:R-HSA-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-HSA-1980143 Signaling by NOTCH1
Reactome:R-HSA-5684996 ERK1/ERK2 pathway
Reactome:R-HSA-110056 MAPK3 (ERK1) activation
Reactome:R-HSA-69615 G1/S DNA Damage Checkpoints
Reactome:R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Reactome:R-HSA-69278 Cell Cycle, Mitotic
Reactome:R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
Reactome:R-HSA-69202 Cyclin E associated events during G1/S transition
Reactome:R-HSA-113507 E2F-enabled inhibition of pre-replication complex formation
Reactome:R-HSA-69275 G2/M Transition
Reactome:R-HSA-380259 Loss of Nlp from mitotic centrosomes
Reactome:R-HSA-2299718 Condensation of Prophase Chromosomes
Reactome:R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly
Reactome:R-HSA-2500257 Resolution of Sister Chromatid Cohesion
Reactome:R-HSA-2995383 Initiation of Nuclear Envelope (NE) Reformation
Reactome:R-HSA-174143 APC/C-mediated degradation of cell cycle proteins
Reactome:R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome:R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Reactome:R-HSA-171319 Telomere Extension By Telomerase
Reactome:R-HSA-5688426 Deubiquitination
Reactome:R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers
Reactome:R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
Reactome:R-HSA-167161 HIV Transcription Initiation
Reactome:R-HSA-167158 Formation of the HIV-1 Early Elongation Complex
Reactome:R-HSA-167287 HIV elongation arrest and recovery
Reactome:R-HSA-4839726 Chromatin organization
Reactome:R-HSA-73864 RNA Polymerase I Transcription
Reactome:R-HSA-212436 Generic Transcription Pathway
Reactome:R-HSA-3700989 Transcriptional Regulation by TP53
Reactome:R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Reactome:R-HSA-5633007 Regulation of TP53 Activity
Reactome:R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation
Reactome:R-HSA-8878171 Transcriptional regulation by RUNX1
Reactome:R-HSA-113418 Formation of the Early Elongation Complex
Reactome:R-HSA-6807505 RNA polymerase II transcribes snRNA genes
Reactome:R-HSA-168256 Immune System
Reactome:R-HSA-389948 PD-1 signaling
Reactome:R-HSA-168249 Innate Immune System
Reactome:R-HSA-975871 MyD88 cascade initiated on plasma membrane
Reactome:R-HSA-450294 MAP kinase activation
Reactome:R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases
Reactome:R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade
Reactome:R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade
Reactome:R-HSA-8953854 Metabolism of RNA
Reactome:R-MMU-69620 Cell Cycle Checkpoints
Reactome:R-MMU-69473 G2/M DNA damage checkpoint
Reactome:R-MMU-69236 G1 Phase
Reactome:R-MMU-187577 SCF(Skp2)-mediated degradation of p27/p21
Reactome:R-MMU-69275 G2/M Transition
Reactome:R-MMU-380287 Centrosome maturation
Reactome:R-MMU-68886 M Phase
Reactome:R-MMU-4419969 Depolymerization of the Nuclear Lamina
Reactome:R-MMU-380320 Recruitment of NuMA to mitotic centrosomes
Reactome:R-MMU-176417 Phosphorylation of Emi1
Reactome:R-MMU-176409 APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome:R-MMU-174048 APC/C:Cdc20 mediated degradation of Cyclin B
Reactome:R-MMU-157579 Telomere Maintenance
Reactome:R-MMU-1280218 Adaptive Immune System
Reactome:R-MMU-168898 Toll-like Receptor Cascades
Reactome:R-MMU-198753 ERK/MAPK targets
Reactome:R-MMU-168164 Toll Like Receptor 3 (TLR3) Cascade
Reactome:R-MMU-975155 MyD88 dependent cascade initiated on endosome
Reactome:R-MMU-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane
Reactome:R-MMU-168179 Toll Like Receptor TLR1:TLR2 Cascade
Reactome:R-MMU-1169410 Antiviral mechanism by IFN-stimulated genes
Reactome:R-MMU-73894 DNA Repair
Reactome:R-MMU-5696395 Formation of Incision Complex in GG-NER
Reactome:R-MMU-6781823 Formation of TC-NER Pre-Incision Complex
Reactome:R-MMU-72086 mRNA Capping
Reactome:R-MMU-1266738 Developmental Biology
Reactome:R-MMU-2559586 DNA Damage/Telomere Stress Induced Senescence
Reactome:R-MMU-1852241 Organelle biogenesis and maintenance
Reactome:R-MMU-5617833 Cilium Assembly
Reactome:R-MMU-73864 RNA Polymerase I Transcription
Reactome:R-MMU-212436 Generic Transcription Pathway
Reactome:R-MMU-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-MMU-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Reactome:R-MMU-8878166 Transcriptional regulation by RUNX2
Reactome:R-MMU-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance
Reactome:R-MMU-75955 RNA Polymerase II Transcription Elongation
Reactome:R-MMU-9006934 Signaling by Receptor Tyrosine Kinases
Reactome:R-MMU-9006936 Signaling by TGFB family members
Reactome:R-MMU-9006931 Signaling by Nuclear Receptors
Reactome:R-MMU-9018519 Estrogen-dependent gene expression
Reactome:R-MMU-5687128 MAPK6/MAPK4 signaling
Reactome:R-MMU-392499 Metabolism of proteins
Reactome:R-MMU-597592 Post-translational protein modification
Reactome:R-MMU-5689896 Ovarian tumor domain proteases
Reactome:R-RNO-4839726 Chromatin organization
Reactome:R-RNO-69615 G1/S DNA Damage Checkpoints
Reactome:R-RNO-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Reactome:R-RNO-69278 Cell Cycle, Mitotic
Reactome:R-RNO-69231 Cyclin D associated events in G1
Reactome:R-RNO-69200 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Reactome:R-RNO-69242 S Phase
Reactome:R-RNO-69052 Switching of origins to a post-replicative state
Reactome:R-RNO-69273 Cyclin A/B1/B2 associated events during G2/M transition
Reactome:R-RNO-380270 Recruitment of mitotic centrosome proteins and complexes
Reactome:R-RNO-68875 Mitotic Prophase
Reactome:R-RNO-2980766 Nuclear Envelope Breakdown
Reactome:R-RNO-68877 Mitotic Prometaphase
Reactome:R-RNO-2555396 Mitotic Metaphase and Anaphase
Reactome:R-RNO-2995410 Nuclear Envelope (NE) Reassembly
Reactome:R-RNO-453276 Regulation of mitotic cell cycle
Reactome:R-RNO-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Reactome:R-RNO-73886 Chromosome Maintenance
Reactome:R-RNO-180786 Extension of Telomeres
Reactome:R-RNO-5688426 Deubiquitination
Reactome:R-RNO-74160 Gene expression (Transcription)
Reactome:R-RNO-73762 RNA Polymerase I Transcription Initiation
Reactome:R-RNO-73857 RNA Polymerase II Transcription
Reactome:R-RNO-3700989 Transcriptional Regulation by TP53
Reactome:R-RNO-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Reactome:R-RNO-5633007 Regulation of TP53 Activity
Reactome:R-RNO-6804756 Regulation of TP53 Activity through Phosphorylation
Reactome:R-RNO-674695 RNA Polymerase II Pre-transcription Events
Reactome:R-RNO-73776 RNA Polymerase II Promoter Escape
Reactome:R-RNO-112382 Formation of RNA Pol II elongation complex
Reactome:R-RNO-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-RNO-5683057 MAPK family signaling cascades
Reactome:R-RNO-112409 RAF-independent MAPK1/3 activation
Reactome:R-RNO-5693532 DNA Double-Strand Break Repair
Reactome:R-RNO-5693538 Homology Directed Repair
Reactome:R-RNO-5696398 Nucleotide Excision Repair
Reactome:R-SCE-674695 RNA Polymerase II Pre-transcription Events
Reactome:R-SPO-69239 Synthesis of DNA
Reactome:R-SPO-69017 CDK-mediated phosphorylation and removal of Cdc6
Reactome:R-SPO-74160 Gene expression (Transcription)
Reactome:R-SPO-8953897 Cellular responses to stimuli
Reactome:R-SPO-2559583 Cellular Senescence
Reactome:R-SSC-3214858 RMTs methylate histone arginines
Reactome:R-SSC-453279 Mitotic G1 phase and G1/S transition
Reactome:R-SSC-1280218 Adaptive Immune System
Reactome:R-XTR-74160 Gene expression (Transcription)
Reactome:R-XTR-73857 RNA Polymerase II Transcription
Reactome:R-XTR-3700989 Transcriptional Regulation by TP53
Reactome:R-XTR-75955 RNA Polymerase II Transcription Elongation
Reactome:R-BTA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Reactome:R-BTA-6807505 RNA polymerase II transcribes snRNA genes
Reactome:R-BTA-69615 G1/S DNA Damage Checkpoints
Reactome:R-BTA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Reactome:R-BTA-69278 Cell Cycle, Mitotic
Reactome:R-BTA-69231 Cyclin D associated events in G1
Reactome:R-BTA-69200 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Reactome:R-BTA-69242 S Phase
Reactome:R-BTA-69052 Switching of origins to a post-replicative state
Reactome:R-BTA-69273 Cyclin A/B1/B2 associated events during G2/M transition
Reactome:R-BTA-380270 Recruitment of mitotic centrosome proteins and complexes
Reactome:R-BTA-8854518 AURKA Activation by TPX2
Reactome:R-BTA-68875 Mitotic Prophase
Reactome:R-BTA-2980766 Nuclear Envelope Breakdown
Reactome:R-BTA-4419969 Depolymerization of the Nuclear Lamina
Reactome:R-BTA-380320 Recruitment of NuMA to mitotic centrosomes
Reactome:R-BTA-176417 Phosphorylation of Emi1
Reactome:R-BTA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Reactome:R-BTA-73886 Chromosome Maintenance
Reactome:R-BTA-180786 Extension of Telomeres
Reactome:R-BTA-3247509 Chromatin modifying enzymes
Reactome:R-BTA-168142 Toll Like Receptor 10 (TLR10) Cascade
Reactome:R-BTA-168176 Toll Like Receptor 5 (TLR5) Cascade
Reactome:R-BTA-166016 Toll Like Receptor 4 (TLR4) Cascade
Reactome:R-BTA-937061 TRIF (TICAM1)-mediated TLR4 signaling
Reactome:R-BTA-5693607 Processing of DNA double-strand break ends
Reactome:R-BTA-1852241 Organelle biogenesis and maintenance
Reactome:R-BTA-5617833 Cilium Assembly
Reactome:R-BTA-69306 DNA Replication
Reactome:R-BTA-166520 Signaling by NTRKs
Reactome:R-BTA-5683057 MAPK family signaling cascades
Reactome:R-BTA-112409 RAF-independent MAPK1/3 activation
Reactome:R-CEL-69620 Cell Cycle Checkpoints
Reactome:R-CEL-69478 G2/M DNA replication checkpoint
Reactome:R-CEL-69236 G1 Phase
Reactome:R-CEL-453274 Mitotic G2-G2/M phases
Reactome:R-CEL-2500257 Resolution of Sister Chromatid Cohesion
Reactome:R-CEL-453276 Regulation of mitotic cell cycle
Reactome:R-CEL-1280215 Cytokine Signaling in Immune system
Reactome:R-CEL-8953854 Metabolism of RNA
Reactome:R-CEL-5696399 Global Genome Nucleotide Excision Repair (GG-NER)
Reactome:R-CEL-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Reactome:R-CEL-2262752 Cellular responses to stress
Reactome:R-CEL-4839726 Chromatin organization
Reactome:R-CEL-73857 RNA Polymerase II Transcription
Reactome:R-CEL-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Reactome:R-CEL-8878171 Transcriptional regulation by RUNX1
Reactome:R-CEL-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
Reactome:R-DRE-74160 Gene expression (Transcription)
Reactome:R-DRE-73857 RNA Polymerase II Transcription
Reactome:R-DRE-674695 RNA Polymerase II Pre-transcription Events
Reactome:R-DDI-5696395 Formation of Incision Complex in GG-NER
Reactome:R-DDI-69052 Switching of origins to a post-replicative state
Reactome:R-DDI-2559583 Cellular Senescence
Reactome:R-DDI-69278 Cell Cycle, Mitotic
Reactome:R-DDI-69231 Cyclin D associated events in G1
Reactome:R-DDI-69242 S Phase
Reactome:R-DDI-176408 Regulation of APC/C activators between G1/S and early anaphase
Reactome:R-DDI-674695 RNA Polymerase II Pre-transcription Events
Reactome:R-DDI-73776 RNA Polymerase II Promoter Escape
Reactome:R-DDI-6807505 RNA polymerase II transcribes snRNA genes
Reactome:R-DDI-72086 mRNA Capping
Reactome:R-DME-69002 DNA Replication Pre-Initiation
Reactome:R-DME-69052 Switching of origins to a post-replicative state
Reactome:R-DME-1280215 Cytokine Signaling in Immune system
Reactome:R-DME-5684996 ERK1/ERK2 pathway
Reactome:R-DME-110056 MAPK3 (ERK1) activation
Reactome:R-DME-1640170 Cell Cycle
Reactome:R-DME-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Reactome:R-DME-1538133 G0 and Early G1
Reactome:R-DME-69202 Cyclin E associated events during G1/S transition
Reactome:R-DME-69275 G2/M Transition
Reactome:R-DME-68877 Mitotic Prometaphase
Reactome:R-DME-68882 Mitotic Anaphase
Reactome:R-DME-176408 Regulation of APC/C activators between G1/S and early anaphase
Reactome:R-DME-176409 APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome:R-DME-174048 APC/C:Cdc20 mediated degradation of Cyclin B
Reactome:R-DME-212436 Generic Transcription Pathway
Reactome:R-DME-6791312 TP53 Regulates Transcription of Cell Cycle Genes
Reactome:R-DME-5633007 Regulation of TP53 Activity
Reactome:R-GGA-353377 DNA repair
Reactome:R-GGA-353295 Homologous recombination repair
Reactome:R-HSA-1852241 Organelle biogenesis and maintenance
Reactome:R-HSA-983231 Factors involved in megakaryocyte development and platelet production
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-73894 DNA Repair
Reactome:R-HSA-5693607 Processing of DNA double-strand break ends
Reactome:R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Reactome:R-HSA-162582 Signaling Pathways
Reactome:R-HSA-166520 Signaling by NTRKs
Reactome:R-HSA-198753 ERK/MAPK targets
Reactome:R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Reactome:R-HSA-8939211 ESR-mediated signaling
Reactome:R-HSA-8953897 Cellular responses to stimuli
Reactome:R-HSA-2559586 DNA Damage/Telomere Stress Induced Senescence
Reactome:R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint
Reactome:R-HSA-69478 G2/M DNA replication checkpoint
Reactome:R-HSA-453279 Mitotic G1 phase and G1/S transition
Reactome:R-HSA-69236 G1 Phase
Reactome:R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21
Reactome:R-HSA-68962 Activation of the pre-replicative complex
Reactome:R-HSA-69242 S Phase
Reactome:R-HSA-69052 Switching of origins to a post-replicative state
Reactome:R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition
Reactome:R-HSA-380287 Centrosome maturation
Reactome:R-HSA-68886 M Phase
Reactome:R-HSA-2465910 MASTL Facilitates Mitotic Progression
Reactome:R-HSA-2514853 Condensation of Prometaphase Chromosomes
Reactome:R-HSA-68882 Mitotic Anaphase
Reactome:R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase
Reactome:R-HSA-176412 Phosphorylation of the APC/C
Reactome:R-HSA-2644603 Signaling by NOTCH1 in Cancer
Reactome:R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Reactome:R-HSA-5663205 Infectious disease
Reactome:R-HSA-167162 RNA Polymerase II HIV Promoter Escape
Reactome:R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript
Reactome:R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat
Reactome:R-HSA-3247509 Chromatin modifying enzymes
Reactome:R-HSA-73854 RNA Polymerase I Promoter Clearance
Reactome:R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Reactome:R-HSA-8934593 Regulation of RUNX1 Expression and Activity
Reactome:R-HSA-8878166 Transcriptional regulation by RUNX2
Reactome:R-HSA-674695 RNA Polymerase II Pre-transcription Events
Reactome:R-HSA-73776 RNA Polymerase II Promoter Escape
Reactome:R-HSA-112382 Formation of RNA Pol II elongation complex
Reactome:R-HSA-1280218 Adaptive Immune System
Reactome:R-HSA-168898 Toll-like Receptor Cascades
Reactome:R-HSA-975155 MyD88 dependent cascade initiated on endosome
Reactome:R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane
Reactome:R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade
Reactome:R-HSA-1280215 Cytokine Signaling in Immune system
Reactome:R-HSA-72086 mRNA Capping
Reactome:R-MMU-69615 G1/S DNA Damage Checkpoints
Reactome:R-MMU-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Reactome:R-MMU-69278 Cell Cycle, Mitotic
Reactome:R-MMU-69231 Cyclin D associated events in G1
Reactome:R-MMU-69200 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
Reactome:R-MMU-69242 S Phase
Reactome:R-MMU-69052 Switching of origins to a post-replicative state
Reactome:R-MMU-69273 Cyclin A/B1/B2 associated events during G2/M transition
Reactome:R-MMU-380270 Recruitment of mitotic centrosome proteins and complexes
Reactome:R-MMU-8854518 AURKA Activation by TPX2
Reactome:R-MMU-68875 Mitotic Prophase
Reactome:R-MMU-2980766 Nuclear Envelope Breakdown
Reactome:R-MMU-68877 Mitotic Prometaphase
Reactome:R-MMU-2555396 Mitotic Metaphase and Anaphase
Reactome:R-MMU-2995410 Nuclear Envelope (NE) Reassembly
Reactome:R-MMU-453276 Regulation of mitotic cell cycle
Reactome:R-MMU-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Reactome:R-MMU-73886 Chromosome Maintenance
Reactome:R-MMU-180786 Extension of Telomeres
Reactome:R-MMU-69306 DNA Replication
Reactome:R-MMU-202670 ERKs are inactivated
Reactome:R-MMU-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Reactome:R-MMU-168138 Toll Like Receptor 9 (TLR9) Cascade
Reactome:R-MMU-166166 MyD88-independent TLR4 cascade
Reactome:R-MMU-168188 Toll Like Receptor TLR6:TLR2 Cascade
Reactome:R-MMU-5693532 DNA Double-Strand Break Repair
Reactome:R-MMU-5693538 Homology Directed Repair
Reactome:R-MMU-5696398 Nucleotide Excision Repair
Reactome:R-MMU-8953897 Cellular responses to stimuli
Reactome:R-MMU-2262752 Cellular responses to stress
Reactome:R-MMU-2559583 Cellular Senescence
Reactome:R-MMU-4839726 Chromatin organization
Reactome:R-MMU-5620912 Anchoring of the basal body to the plasma membrane
Reactome:R-MMU-73854 RNA Polymerase I Promoter Clearance
Reactome:R-MMU-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Reactome:R-MMU-8878171 Transcriptional regulation by RUNX1
Reactome:R-MMU-113418 Formation of the Early Elongation Complex
Reactome:R-MMU-6807505 RNA polymerase II transcribes snRNA genes
Reactome:R-MMU-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-MMU-5683057 MAPK family signaling cascades
Reactome:R-MMU-112409 RAF-independent MAPK1/3 activation
Reactome:R-MMU-5688426 Deubiquitination
Reactome:R-RNO-3247509 Chromatin modifying enzymes
Reactome:R-RNO-3214858 RMTs methylate histone arginines
Reactome:R-RNO-8953854 Metabolism of RNA
Reactome:R-RNO-69580 p53-Dependent G1/S DNA damage checkpoint
Reactome:R-RNO-69478 G2/M DNA replication checkpoint
Reactome:R-RNO-453279 Mitotic G1 phase and G1/S transition
Reactome:R-RNO-69206 G1/S Transition
Reactome:R-RNO-68962 Activation of the pre-replicative complex
Reactome:R-RNO-69656 Cyclin A:Cdk2-associated events at S phase entry
Reactome:R-RNO-68949 Orc1 removal from chromatin
Reactome:R-RNO-453274 Mitotic G2-G2/M phases
Reactome:R-RNO-2565942 Regulation of PLK1 Activity at G2/M Transition
Reactome:R-RNO-380284 Loss of proteins required for interphase microtubule organization from the centrosome
Reactome:R-RNO-2980767 Activation of NIMA Kinases NEK9, NEK6, NEK7
Reactome:R-RNO-2500257 Resolution of Sister Chromatid Cohesion
Reactome:R-RNO-2995383 Initiation of Nuclear Envelope (NE) Reformation
Reactome:R-RNO-174143 APC/C-mediated degradation of cell cycle proteins
Reactome:R-RNO-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Reactome:R-RNO-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Reactome:R-RNO-171319 Telomere Extension By Telomerase
Reactome:R-RNO-73864 RNA Polymerase I Transcription
Reactome:R-RNO-212436 Generic Transcription Pathway
Reactome:R-RNO-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-RNO-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Reactome:R-RNO-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs
Reactome:R-RNO-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
Reactome:R-RNO-2559586 DNA Damage/Telomere Stress Induced Senescence
Reactome:R-RNO-5684996 ERK1/ERK2 pathway
Reactome:R-RNO-110056 MAPK3 (ERK1) activation
Reactome:R-RNO-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
Reactome:R-RNO-5696399 Global Genome Nucleotide Excision Repair (GG-NER)
Reactome:R-RNO-388841 Costimulation by the CD28 family
Reactome:R-RNO-1280215 Cytokine Signaling in Immune system
Reactome:R-SCE-74160 Gene expression (Transcription)
Reactome:R-SCE-73857 RNA Polymerase II Transcription
Reactome:R-SCE-69278 Cell Cycle, Mitotic
Reactome:R-SCE-69306 DNA Replication
Reactome:R-SPO-69278 Cell Cycle, Mitotic
Reactome:R-SPO-453276 Regulation of mitotic cell cycle
Reactome:R-SPO-73857 RNA Polymerase II Transcription
Reactome:R-SPO-674695 RNA Polymerase II Pre-transcription Events
Reactome:R-SSC-74160 Gene expression (Transcription)
Reactome:R-SSC-73857 RNA Polymerase II Transcription
Reactome:R-SSC-1640170 Cell Cycle
Reactome:R-SSC-75815 Ubiquitin-dependent degradation of Cyclin D
Reactome:R-SSC-1266738 Developmental Biology
Reactome:R-XTR-212436 Generic Transcription Pathway
Reactome:R-XTR-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-XTR-6807505 RNA polymerase II transcribes snRNA genes
Reactome:R-XTR-162582 Signaling Pathways
Reactome:R-XTR-8939211 ESR-mediated signaling
WikiPathways:WP5144 NRP1-triggered signaling pathways in pancreatic cancer
WikiPathways:WP5287 17q12 copy number variation syndrome
WikiPathways:WP5381 Smith-Magenis and Potocki-Lupski syndrome copy number variation
WikiPathways:WP3998 Prader-Willi and Angelman syndrome
WikiPathways:WP5055 Burn wound healing
WikiPathways:WP1971 Integrated cancer pathway
WikiPathways:WP2516 ATM signaling pathway
WikiPathways:WP4016 DNA IR-damage and cellular response via ATR
WikiPathways:WP2263 Androgen receptor network in prostate cancer
WikiPathways:WP5322 CKAP4 signaling pathway map
WikiPathways:WP1984 Integrated breast cancer pathway
PathBank:SMP0063782 P53 Signaling Pathway
PathBank:SMP0100467 P53 Signaling Pathway
PathBank:SMP0100482 P53 Signaling Pathway
PathBank:SMP0100497 P53 Signaling Pathway