Formation of the Early Elongation Complex

Yamaguchi Y, Inukai N, Narita T, Wada T, Handa H. Evidence that Negative Elongation Factor Represses Transcription Elongation through Binding to a DRB Sensitivity-Inducing Factor/RNA Polymerase II Complex and RNA. Molecular and Cellular Biology. 2002 May 01;22(9):2918–27. doi: 10.1128/mcb.22.9.2918-2927.2002.; Conaway JW, Shilatifard A, Dvir A, Conaway RC. Control of elongation by RNA polymerase II. Trends Biochem Sci. 2000 Aug;25(8):375–80. doi: 10.1016/s0968-0004(00)01615-7. PMID: 10916156.

Metabolites



Enzyme

EC Number name full name note
3.1.13.-
2.7.11.22 cyclin-dependent kinase ATP:cyclin phosphotransferase
2.7.11.23 [RNA-polymerase]-subunit kinase ATP:[DNA-directed RNA polymerase] phosphotransferase
2.7.7.48 RNA-directed RNA polymerase nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
2.7.7.6 DNA-directed RNA polymerase nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed)
3.1.3.16 protein-serine/threonine phosphatase protein-serine/threonine-phosphate phosphohydrolase
5.6.2.3 DNA 5'-3' helicase DNA 5'-3' helicase (ATP-hydrolysing)
5.6.2.4 DNA 3'-5' helicase DNA 3'-5' helicase (ATP-hydrolysing)


Proteins

Protein ID name full name