| BioCyc:HUMAN_PWY-7899 |
protein neddylation |
| BioCyc:META_PWY-7899 |
protein NEDDylation |
| BioCyc:MOUSE_PWY-5004 |
superpathway of citrulline metabolism |
| BioCyc:MOUSE_PWY-4983 |
citrulline-nitric oxide cycle |
| Plant Reactome:R-OSA-9030769 |
Growth and developmental processes |
| Plant Reactome:R-OSA-8934108 |
Short day regulated expression of florigens |
| Plant Reactome:R-OSA-9031670 |
Vegetative structure development |
| Plant Reactome:R-OSA-9623902 |
Seed development |
| Plant Reactome:R-OSA-9640032 |
Root structure development |
| Plant Reactome:R-OSA-9035605 |
Regulation of seed size |
| Plant Reactome:R-OSA-9611432 |
Cell Death and immunity |
| Plant Reactome:R-OSA-9031669 |
Reproductive structure development |
| Plant Reactome:R-OSA-9030654 |
Primary root development |
| Plant Reactome:R-OSA-8934088 |
Inflorescence development |
| Plant Reactome:R-OSA-9612650 |
Responses to stimuli: biotic stimuli and stresses |
| Reactome:R-DRE-9639288 |
Amino acids regulate mTORC1 |
| Reactome:R-SSC-9645460 |
ALPK1 signaling pathway |
| Reactome:R-MMU-9639288 |
Amino acids regulate mTORC1 |
| Reactome:R-HSA-9639288 |
Amino acids regulate mTORC1 |
| Reactome:R-HSA-9607240 |
FLT3 Signaling |
| Reactome:R-HSA-9635486 |
Infection with Mycobacterium tuberculosis |
| Reactome:R-HSA-9645460 |
ALPK1 signaling pathway |
| Reactome:R-HSA-9649948 |
Signaling downstream of RAS mutants |
| Reactome:R-HSA-9609690 |
HCMV Early Events |
| Reactome:R-HSA-9031525 |
LXRs regulate gene expression to limit cholesterol uptake |
| Reactome:R-RNO-9645460 |
ALPK1 signaling pathway |
| Reactome:R-DDI-9639288 |
Amino acids regulate mTORC1 |
| Reactome:R-MMU-9607240 |
FLT3 Signaling |
| Reactome:R-HSA-9637690 |
Response of Mtb to phagocytosis |
| Reactome:R-HSA-9609646 |
HCMV Infection |
| Reactome:R-HSA-9645723 |
Diseases of programmed cell death |
| Reactome:R-XTR-9645460 |
ALPK1 signaling pathway |
| Reactome:R-BTA-9645460 |
ALPK1 signaling pathway |
| Reactome:R-HSA-9635465 |
Suppression of apoptosis |
| Reactome:R-HSA-9024446 |
LXR-mediated signaling |
| Reactome:R-HSA-9675135 |
Diseases of DNA repair |
| Reactome:R-HSA-9679506 |
SARS-CoV Infections |
| Reactome:R-HSA-9679191 |
Potential therapeutics for SARS |
| Reactome:R-HSA-9693928 |
Defective RIPK1-mediated regulated necrosis |
| Reactome:R-HSA-9694516 |
SARS-CoV-2 Infection |
| Reactome:R-DRE-9711097 |
Cellular response to starvation |
| Reactome:R-DME-9711123 |
Cellular response to chemical stress |
| Reactome:R-HSA-9674555 |
Signaling by CSF3 (G-CSF) |
| Reactome:R-HSA-9700206 |
Signaling by ALK in cancer |
| Reactome:R-CFA-937041 |
IKK complex recruitment mediated by RIP1 |
| Reactome:R-HSA-9758941 |
Gastrulation |
| Reactome:R-MMU-9759194 |
Nuclear events mediated by NFE2L2 |
| Reactome:R-HSA-9692914 |
SARS-CoV-1-host interactions |
| Reactome:R-HSA-9824439 |
Bacterial Infection Pathways |
| Reactome:R-DRE-9759476 |
Regulation of Homotypic Cell-Cell Adhesion |
| Reactome:R-HSA-9821002 |
Chromatin modifications during the maternal to zygotic transition (MZT) |
| Reactome:R-HSA-9861718 |
Regulation of pyruvate metabolism |
| Reactome:R-HSA-9856651 |
MITF-M-dependent gene expression |
| Reactome:R-HSA-9675108 |
Nervous system development |
| Reactome:R-RNO-111459 |
Activation of caspases through apoptosome-mediated cleavage |
| Reactome:R-MMU-111459 |
Activation of caspases through apoptosome-mediated cleavage |
| Reactome:R-HSA-9699150 |
Defective DNA double strand break response due to BARD1 loss of function |
| Reactome:R-MMU-9705462 |
Inactivation of CSF3 (G-CSF) signaling |
| Reactome:R-HSA-9711097 |
Cellular response to starvation |
| Reactome:R-BTA-9755511 |
KEAP1-NFE2L2 pathway |
| Reactome:R-HSA-9705671 |
SARS-CoV-2 activates/modulates innate and adaptive immune responses |
| Reactome:R-HSA-9762114 |
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 |
| Reactome:R-MMU-9755511 |
KEAP1-NFE2L2 pathway |
| Reactome:R-HSA-9692916 |
SARS-CoV-1 activates/modulates innate immune responses |
| Reactome:R-HSA-9833109 |
Evasion by RSV of host interferon responses |
| Reactome:R-BTA-9861718 |
Regulation of pyruvate metabolism |
| Reactome:R-HSA-9824594 |
Regulation of MITF-M-dependent genes involved in apoptosis |
| Reactome:R-HSA-9678108 |
SARS-CoV-1 Infection |
| Reactome:R-HSA-9706369 |
Negative regulation of FLT3 |
| Reactome:R-HSA-9675136 |
Diseases of DNA Double-Strand Break Repair |
| Reactome:R-BTA-9711123 |
Cellular response to chemical stress |
| Reactome:R-DDI-9711097 |
Cellular response to starvation |
| Reactome:R-MMU-9711123 |
Cellular response to chemical stress |
| Reactome:R-MMU-9708530 |
Regulation of BACH1 activity |
| Reactome:R-HSA-9705462 |
Inactivation of CSF3 (G-CSF) signaling |
| Reactome:R-HSA-9725370 |
Signaling by ALK fusions and activated point mutants |
| Reactome:R-HSA-9755511 |
KEAP1-NFE2L2 pathway |
| Reactome:R-HSA-9754189 |
Primitive streak formation |
| Reactome:R-MMU-9762114 |
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 |
| Reactome:R-HSA-9634815 |
Transcriptional Regulation by NPAS4 |
| Reactome:R-HSA-9768919 |
NPAS4 regulates expression of target genes |
| Reactome:R-HSA-9680350 |
Signaling by CSF1 (M-CSF) in myeloid cells |
| Reactome:R-HSA-9824446 |
Viral Infection Pathways |
| Reactome:R-HSA-9759476 |
Regulation of Homotypic Cell-Cell Adhesion |
| Reactome:R-HSA-9816359 |
Maternal to zygotic transition (MZT) |
| Reactome:R-MMU-9833482 |
PKR-mediated signaling |
| Reactome:R-MMU-9706369 |
Negative regulation of FLT3 |
| Reactome:R-HSA-9663199 |
Defective DNA double strand break response due to BRCA1 loss of function |
| Reactome:R-MMU-9711097 |
Cellular response to starvation |
| Reactome:R-MMU-9674555 |
Signaling by CSF3 (G-CSF) |
| Reactome:R-HSA-9711123 |
Cellular response to chemical stress |
| Reactome:R-HSA-9708530 |
Regulation of BACH1 activity |
| Reactome:R-HSA-9725371 |
Nuclear events stimulated by ALK signaling in cancer |
| Reactome:R-DME-9755511 |
KEAP1-NFE2L2 pathway |
| Reactome:R-HSA-9705683 |
SARS-CoV-2-host interactions |
| Reactome:R-HSA-9759194 |
Nuclear events mediated by NFE2L2 |
| Reactome:R-CFA-9759476 |
Regulation of Homotypic Cell-Cell Adhesion |
| Reactome:R-HSA-9833482 |
PKR-mediated signaling |
| Reactome:R-HSA-9820841 |
M-decay: degradation of maternal mRNAs by maternally stored factors |
| Reactome:R-MMU-9759476 |
Regulation of Homotypic Cell-Cell Adhesion |
| Reactome:R-HSA-9820952 |
Respiratory Syncytial Virus Infection Pathway |
| Reactome:R-HSA-9833110 |
RSV-host interactions |
| Reactome:R-RNO-937041 |
IKK complex recruitment mediated by RIP1 |
| Reactome:R-DRE-9861718 |
Regulation of pyruvate metabolism |
| Reactome:R-GGA-9861718 |
Regulation of pyruvate metabolism |
| Reactome:R-HSA-9730414 |
MITF-M-regulated melanocyte development |
| Reactome:R-HSA-9825895 |
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence |
| Reactome:R-MMU-9861718 |
Regulation of pyruvate metabolism |
| Reactome:R-RNO-9861718 |
Regulation of pyruvate metabolism |
| Reactome:R-MMU-9842860 |
Regulation of endogenous retroelements |
| Reactome:R-RNO-9842860 |
Regulation of endogenous retroelements |
| Reactome:R-HSA-9932298 |
Degradation of CRY and PER proteins |
| Reactome:R-CFA-9764274 |
Regulation of Expression and Function of Type I Classical Cadherins |
| Reactome:R-DRE-9764265 |
Regulation of CDH1 Expression and Function |
| Reactome:R-DRE-9764561 |
Regulation of CDH1 Function |
| Reactome:R-HSA-9764265 |
Regulation of CDH1 Expression and Function |
| Reactome:R-MMU-9764265 |
Regulation of CDH1 Expression and Function |
| Reactome:R-MMU-9764561 |
Regulation of CDH1 Function |
| Reactome:R-DRE-9954716 |
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA |
| Reactome:R-DRE-389948 |
PD-1 signaling |
| Reactome:R-HSA-9929491 |
SPOP-mediated proteasomal degradation of PD-L1(CD274) |
| Reactome:R-MMU-9954709 |
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide |
| Reactome:R-MMU-9929356 |
GSK3B-mediated proteasomal degradation of PD-L1(CD274) |
| Reactome:R-SPO-9948299 |
Ribosome-associated quality control |
| Reactome:R-HSA-9842860 |
Regulation of endogenous retroelements |
| Reactome:R-DRE-9764274 |
Regulation of Expression and Function of Type I Classical Cadherins |
| Reactome:R-HSA-9764274 |
Regulation of Expression and Function of Type I Classical Cadherins |
| Reactome:R-HSA-9766229 |
Degradation of CDH1 |
| Reactome:R-HSA-9640148 |
Infection with Enterobacteria |
| Reactome:R-MMU-9764274 |
Regulation of Expression and Function of Type I Classical Cadherins |
| Reactome:R-CEL-9909648 |
Regulation of PD-L1(CD274) expression |
| Reactome:R-CEL-9931269 |
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) |
| Reactome:R-CEL-9948299 |
Ribosome-associated quality control |
| Reactome:R-DRE-9948299 |
Ribosome-associated quality control |
| Reactome:R-DRE-9909615 |
Regulation of PD-L1(CD274) Post-translational modification |
| Reactome:R-HSA-9954716 |
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA |
| Reactome:R-HSA-9909648 |
Regulation of PD-L1(CD274) expression |
| Reactome:R-HSA-9929356 |
GSK3B-mediated proteasomal degradation of PD-L1(CD274) |
| Reactome:R-MMU-9909615 |
Regulation of PD-L1(CD274) Post-translational modification |
| Reactome:R-MMU-9931295 |
PD-L1(CD274) glycosylation and translocation to plasma membrane |
| Reactome:R-RNO-9909615 |
Regulation of PD-L1(CD274) Post-translational modification |
| Reactome:R-RNO-9931295 |
PD-L1(CD274) glycosylation and translocation to plasma membrane |
| Reactome:R-SCE-9948299 |
Ribosome-associated quality control |
| Reactome:R-SPO-9954709 |
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide |
| Reactome:R-HSA-9920588 |
Dengue virus activates/modulates innate and adaptive immune responses |
| Reactome:R-MMU-9770562 |
mRNA Polyadenylation |
| Reactome:R-HSA-9843940 |
Regulation of endogenous retroelements by KRAB-ZFP proteins |
| Reactome:R-MMU-9843940 |
Regulation of endogenous retroelements by KRAB-ZFP proteins |
| Reactome:R-RNO-9843940 |
Regulation of endogenous retroelements by KRAB-ZFP proteins |
| Reactome:R-HSA-9909396 |
Circadian clock |
| Reactome:R-CFA-9764265 |
Regulation of CDH1 Expression and Function |
| Reactome:R-CFA-9764561 |
Regulation of CDH1 Function |
| Reactome:R-DRE-9766229 |
Degradation of CDH1 |
| Reactome:R-MMU-9766229 |
Degradation of CDH1 |
| Reactome:R-CEL-9909615 |
Regulation of PD-L1(CD274) Post-translational modification |
| Reactome:R-DRE-9909648 |
Regulation of PD-L1(CD274) expression |
| Reactome:R-DDI-9954709 |
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide |
| Reactome:R-DME-9954709 |
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide |
| Reactome:R-HSA-9954709 |
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide |
| Reactome:R-MMU-9948299 |
Ribosome-associated quality control |
| Reactome:R-MMU-9909648 |
Regulation of PD-L1(CD274) expression |
| Reactome:R-MMU-9929491 |
SPOP-mediated proteasomal degradation of PD-L1(CD274) |
| Reactome:R-RNO-9909648 |
Regulation of PD-L1(CD274) expression |
| Reactome:R-DRE-9931269 |
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) |
| Reactome:R-HSA-9839923 |
Dengue Virus Infection |
| Reactome:R-CFA-9766229 |
Degradation of CDH1 |
| Reactome:R-HSA-9764561 |
Regulation of CDH1 Function |
| Reactome:R-CEL-389948 |
PD-1 signaling |
| Reactome:R-CEL-9954709 |
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide |
| Reactome:R-DDI-9948299 |
Ribosome-associated quality control |
| Reactome:R-DME-9948299 |
Ribosome-associated quality control |
| Reactome:R-HSA-9948299 |
Ribosome-associated quality control |
| Reactome:R-HSA-9956593 |
Enterobacterial factors antagonize host defense |
| Reactome:R-HSA-9909615 |
Regulation of PD-L1(CD274) Post-translational modification |
| Reactome:R-HSA-9931295 |
PD-L1(CD274) glycosylation and translocation to plasma membrane |
| Reactome:R-MMU-9954716 |
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA |
| Reactome:R-SCE-9954709 |
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide |
| Reactome:R-HSA-9770562 |
mRNA Polyadenylation |
| Reactome:R-HSA-9918481 |
Dengue Virus-Host Interactions |
| Reactome:R-CEL-210991 |
Basigin interactions |
| Reactome:R-RNO-9627069 |
Regulation of the apoptosome activity |
| Reactome:R-SPO-72163 |
pre-mRNA splicing |
| Reactome:R-DDI-72203 |
Processing of Capped Intron-Containing Pre-mRNA |
| Reactome:R-MMU-111458 |
Formation of apoptosome |
| Reactome:R-HSA-9614085 |
FOXO-mediated transcription |
| Reactome:R-RNO-111458 |
Formation of apoptosome |
| Reactome:R-MMU-111461 |
Cytochrome c-mediated apoptotic response |
| Reactome:R-DRE-937072 |
TRAF6-mediated induction of TAK1 complex within TLR4 complex |
| Reactome:R-DRE-198323 |
AKT phosphorylates targets in the cytosol |
| Reactome:R-DDI-72172 |
mRNA Splicing |
| Reactome:R-MMU-9627069 |
Regulation of the apoptosome activity |
| Reactome:R-HSA-9615017 |
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes |
| Reactome:R-RNO-111461 |
Cytochrome c-mediated apoptotic response |
| Reactome:R-DDI-72163 |
pre-mRNA splicing |
| Reactome:R-HSA-9627069 |
Regulation of the apoptosome activity |
| Reactome:R-BTA-597592 |
Post-translational protein modification |
| Reactome:R-BTA-2990846 |
SUMOylation |
| Reactome:R-BTA-3108214 |
SUMOylation of DNA damage response and repair proteins |
| Reactome:R-BTA-5689896 |
Ovarian tumor domain proteases |
| Reactome:R-BTA-168256 |
Immune System |
| Reactome:R-BTA-168898 |
Toll-like Receptor Cascades |
| Reactome:R-BTA-937039 |
IRAK1 recruits IKK complex |
| Reactome:R-BTA-450321 |
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| Reactome:R-BTA-168164 |
Toll Like Receptor 3 (TLR3) Cascade |
| Reactome:R-BTA-975155 |
MyD88 dependent cascade initiated on endosome |
| Reactome:R-BTA-166058 |
MyD88:MAL(TIRAP) cascade initiated on plasma membrane |
| Reactome:R-BTA-937041 |
IKK complex recruitment mediated by RIP1 |
| Reactome:R-BTA-168179 |
Toll Like Receptor TLR1:TLR2 Cascade |
| Reactome:R-BTA-1834949 |
Cytosolic sensors of pathogen-associated DNA |
| Reactome:R-BTA-2454202 |
Fc epsilon receptor (FCERI) signaling |
| Reactome:R-BTA-449147 |
Signaling by Interleukins |
| Reactome:R-BTA-448424 |
Interleukin-17 signaling |
| Reactome:R-BTA-72172 |
mRNA Splicing |
| Reactome:R-BTA-1430728 |
Metabolism |
| Reactome:R-BTA-1428517 |
Aerobic respiration and respiratory electron transport |
| Reactome:R-BTA-5693532 |
DNA Double-Strand Break Repair |
| Reactome:R-BTA-5693538 |
Homology Directed Repair |
| Reactome:R-BTA-5696398 |
Nucleotide Excision Repair |
| Reactome:R-BTA-6782135 |
Dual incision in TC-NER |
| Reactome:R-BTA-8953897 |
Cellular responses to stimuli |
| Reactome:R-BTA-2262752 |
Cellular responses to stress |
| Reactome:R-BTA-4641257 |
Degradation of AXIN |
| Reactome:R-BTA-6807070 |
PTEN Regulation |
| Reactome:R-BTA-209543 |
p75NTR recruits signalling complexes |
| Reactome:R-CEL-202733 |
Cell surface interactions at the vascular wall |
| Reactome:R-CEL-1280218 |
Adaptive Immune System |
| Reactome:R-CEL-388841 |
Costimulation by the CD28 family |
| Reactome:R-CEL-72203 |
Processing of Capped Intron-Containing Pre-mRNA |
| Reactome:R-CEL-72766 |
Translation |
| Reactome:R-CEL-73894 |
DNA Repair |
| Reactome:R-CEL-6782135 |
Dual incision in TC-NER |
| Reactome:R-CEL-5683057 |
MAPK family signaling cascades |
| Reactome:R-CEL-9006925 |
Intracellular signaling by second messengers |
| Reactome:R-CEL-382556 |
ABC-family proteins mediated transport |
| Reactome:R-CFA-2559585 |
Oncogene Induced Senescence |
| Reactome:R-CFA-421270 |
Cell-cell junction organization |
| Reactome:R-CFA-166016 |
Toll Like Receptor 4 (TLR4) Cascade |
| Reactome:R-CFA-597592 |
Post-translational protein modification |
| Reactome:R-CFA-112315 |
Transmission across Chemical Synapses |
| Reactome:R-CFA-112314 |
Neurotransmitter receptors and postsynaptic signal transmission |
| Reactome:R-CFA-399721 |
Glutamate binding, activation of AMPA receptors and synaptic plasticity |
| Reactome:R-CFA-69620 |
Cell Cycle Checkpoints |
| Reactome:R-CFA-69541 |
Stabilization of p53 |
| Reactome:R-CFA-6806003 |
Regulation of TP53 Expression and Degradation |
| Reactome:R-DRE-9006934 |
Signaling by Receptor Tyrosine Kinases |
| Reactome:R-DRE-5358351 |
Signaling by Hedgehog |
| Reactome:R-DRE-1257604 |
PI3K/AKT Signaling |
| Reactome:R-DRE-73887 |
Death Receptor Signaling |
| Reactome:R-DRE-209543 |
p75NTR recruits signalling complexes |
| Reactome:R-DRE-8878159 |
Transcriptional regulation by RUNX3 |
| Reactome:R-DRE-69615 |
G1/S DNA Damage Checkpoints |
| Reactome:R-DRE-382551 |
Transport of small molecules |
| Reactome:R-DRE-1500931 |
Cell-Cell communication |
| Reactome:R-DRE-392499 |
Metabolism of proteins |
| Reactome:R-DRE-3899300 |
SUMOylation of transcription cofactors |
| Reactome:R-DRE-4615885 |
SUMOylation of DNA replication proteins |
| Reactome:R-DRE-5689880 |
Ub-specific processing proteases |
| Reactome:R-DRE-8852135 |
Protein ubiquitination |
| Reactome:R-DRE-1280218 |
Adaptive Immune System |
| Reactome:R-DRE-937042 |
IRAK2 mediated activation of TAK1 complex |
| Reactome:R-DRE-450302 |
activated TAK1 mediates p38 MAPK activation |
| Reactome:R-DRE-168164 |
Toll Like Receptor 3 (TLR3) Cascade |
| Reactome:R-DRE-975155 |
MyD88 dependent cascade initiated on endosome |
| Reactome:R-DRE-166166 |
MyD88-independent TLR4 cascade |
| Reactome:R-DRE-168179 |
Toll Like Receptor TLR1:TLR2 Cascade |
| Reactome:R-DRE-168643 |
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways |
| Reactome:R-DRE-1280215 |
Cytokine Signaling in Immune system |
| Reactome:R-DRE-449147 |
Signaling by Interleukins |
| Reactome:R-DDI-73894 |
DNA Repair |
| Reactome:R-DDI-6781823 |
Formation of TC-NER Pre-Incision Complex |
| Reactome:R-DDI-72766 |
Translation |
| Reactome:R-DDI-597592 |
Post-translational protein modification |
| Reactome:R-DDI-8866654 |
E3 ubiquitin ligases ubiquitinate target proteins |
| Reactome:R-DDI-9609507 |
Protein localization |
| Reactome:R-DME-3247509 |
Chromatin modifying enzymes |
| Reactome:R-DME-597592 |
Post-translational protein modification |
| Reactome:R-DME-3108232 |
SUMO E3 ligases SUMOylate target proteins |
| Reactome:R-DME-4570464 |
SUMOylation of RNA binding proteins |
| Reactome:R-DME-5688426 |
Deubiquitination |
| Reactome:R-DME-8866654 |
E3 ubiquitin ligases ubiquitinate target proteins |
| Reactome:R-DME-8943724 |
Regulation of PTEN gene transcription |
| Reactome:R-DME-2559583 |
Cellular Senescence |
| Reactome:R-DME-390150 |
DS ligand bound to FT receptor |
| Reactome:R-GGA-597592 |
Post-translational protein modification |
| Reactome:R-GGA-4839726 |
Chromatin organization |
| Reactome:R-HSA-8964043 |
Plasma lipoprotein clearance |
| Reactome:R-HSA-422475 |
Axon guidance |
| Reactome:R-HSA-376176 |
Signaling by ROBO receptors |
| Reactome:R-HSA-418990 |
Adherens junctions interactions |
| Reactome:R-HSA-1474165 |
Reproduction |
| Reactome:R-HSA-912446 |
Meiotic recombination |
| Reactome:R-HSA-8982491 |
Glycogen metabolism |
| Reactome:R-HSA-196791 |
Vitamin D (calciferol) metabolism |
| Reactome:R-HSA-202131 |
Metabolism of nitric oxide: NOS3 activation and regulation |
| Reactome:R-HSA-140534 |
Ligand-dependent caspase activation |
| Reactome:R-HSA-109606 |
Intrinsic Pathway for Apoptosis |
| Reactome:R-HSA-111471 |
Apoptotic factor-mediated response |
| Reactome:R-HSA-111469 |
SMAC, XIAP-regulated apoptotic response |
| Reactome:R-HSA-111465 |
Apoptotic cleavage of cellular proteins |
| Reactome:R-HSA-5675482 |
Regulation of necroptotic cell death |
| Reactome:R-HSA-110314 |
Recognition of DNA damage by PCNA-containing replication complex |
| Reactome:R-HSA-5693532 |
DNA Double-Strand Break Repair |
| Reactome:R-HSA-5693538 |
Homology Directed Repair |
| Reactome:R-HSA-5693554 |
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) |
| Reactome:R-HSA-5696398 |
Nucleotide Excision Repair |
| Reactome:R-HSA-5696400 |
Dual Incision in GG-NER |
| Reactome:R-HSA-6782135 |
Dual incision in TC-NER |
| Reactome:R-HSA-177929 |
Signaling by EGFR |
| Reactome:R-HSA-5654738 |
Signaling by FGFR2 |
| Reactome:R-HSA-5654732 |
Negative regulation of FGFR3 signaling |
| Reactome:R-HSA-1227986 |
Signaling by ERBB2 |
| Reactome:R-HSA-8863795 |
Downregulation of ERBB2 signaling |
| Reactome:R-HSA-9006936 |
Signaling by TGFB family members |
| Reactome:R-HSA-157118 |
Signaling by NOTCH |
| Reactome:R-HSA-201681 |
TCF dependent signaling in response to WNT |
| Reactome:R-HSA-5610780 |
Degradation of GLI1 by the proteasome |
| Reactome:R-HSA-5683057 |
MAPK family signaling cascades |
| Reactome:R-HSA-9006925 |
Intracellular signaling by second messengers |
| Reactome:R-HSA-199418 |
Negative regulation of the PI3K/AKT network |
| Reactome:R-HSA-9006927 |
Signaling by Non-Receptor Tyrosine Kinases |
| Reactome:R-HSA-75893 |
TNF signaling |
| Reactome:R-HSA-5357905 |
Regulation of TNFR1 signaling |
| Reactome:R-HSA-204998 |
Cell death signalling via NRAGE, NRIF and NADE |
| Reactome:R-HSA-193692 |
Regulated proteolysis of p75NTR |
| Reactome:R-HSA-2559585 |
Oncogene Induced Senescence |
| Reactome:R-HSA-445355 |
Smooth Muscle Contraction |
| Reactome:R-HSA-112315 |
Transmission across Chemical Synapses |
| Reactome:R-HSA-112314 |
Neurotransmitter receptors and postsynaptic signal transmission |
| Reactome:R-HSA-399721 |
Glutamate binding, activation of AMPA receptors and synaptic plasticity |
| Reactome:R-HSA-69620 |
Cell Cycle Checkpoints |
| Reactome:R-HSA-69541 |
Stabilization of p53 |
| Reactome:R-HSA-69613 |
p53-Independent G1/S DNA Damage Checkpoint |
| Reactome:R-HSA-69239 |
Synthesis of DNA |
| Reactome:R-HSA-8854050 |
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis |
| Reactome:R-HSA-392499 |
Metabolism of proteins |
| Reactome:R-HSA-597592 |
Post-translational protein modification |
| Reactome:R-HSA-2990846 |
SUMOylation |
| Reactome:R-HSA-3108214 |
SUMOylation of DNA damage response and repair proteins |
| Reactome:R-HSA-4090294 |
SUMOylation of intracellular receptors |
| Reactome:R-HSA-4755510 |
SUMOylation of immune response proteins |
| Reactome:R-HSA-5689896 |
Ovarian tumor domain proteases |
| Reactome:R-HSA-381070 |
IRE1alpha activates chaperones |
| Reactome:R-HSA-1643685 |
Disease |
| Reactome:R-HSA-1236382 |
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants |
| Reactome:R-HSA-5674400 |
Constitutive Signaling by AKT1 E17K in Cancer |
| Reactome:R-HSA-2644606 |
Constitutive Signaling by NOTCH1 PEST Domain Mutants |
| Reactome:R-HSA-2644607 |
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling |
| Reactome:R-HSA-6802957 |
Oncogenic MAPK signaling |
| Reactome:R-HSA-6802955 |
Paradoxical activation of RAF signaling by kinase inactive BRAF |
| Reactome:R-HSA-162909 |
Host Interactions of HIV factors |
| Reactome:R-HSA-5260271 |
Diseases of Immune System |
| Reactome:R-HSA-74160 |
Gene expression (Transcription) |
| Reactome:R-HSA-73857 |
RNA Polymerase II Transcription |
| Reactome:R-HSA-6791312 |
TP53 Regulates Transcription of Cell Cycle Genes |
| Reactome:R-HSA-6804757 |
Regulation of TP53 Degradation |
| Reactome:R-HSA-5334118 |
DNA methylation |
| Reactome:R-HSA-388841 |
Costimulation by the CD28 family |
| Reactome:R-HSA-168142 |
Toll Like Receptor 10 (TLR10) Cascade |
| Reactome:R-HSA-445989 |
TAK1-dependent IKK and NF-kappa-B activation |
| Reactome:R-HSA-9013973 |
TICAM1-dependent activation of IRF3/IRF7 |
| Reactome:R-HSA-168176 |
Toll Like Receptor 5 (TLR5) Cascade |
| Reactome:R-HSA-975144 |
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation |
| Reactome:R-HSA-166016 |
Toll Like Receptor 4 (TLR4) Cascade |
| Reactome:R-HSA-937061 |
TRIF (TICAM1)-mediated TLR4 signaling |
| Reactome:R-HSA-937072 |
TRAF6-mediated induction of TAK1 complex within TLR4 complex |
| Reactome:R-HSA-168638 |
NOD1/2 Signaling Pathway |
| Reactome:R-HSA-918233 |
TRAF3-dependent IRF activation pathway |
| Reactome:R-HSA-936440 |
Negative regulators of RIG-I/MDA5 signaling |
| Reactome:R-HSA-5607764 |
CLEC7A (Dectin-1) signaling |
| Reactome:R-HSA-1169410 |
Antiviral mechanism by IFN-stimulated genes |
| Reactome:R-HSA-446652 |
Interleukin-1 family signaling |
| Reactome:R-HSA-1266695 |
Interleukin-7 signaling |
| Reactome:R-HSA-448424 |
Interleukin-17 signaling |
| Reactome:R-HSA-1170546 |
Prolactin receptor signaling |
| Reactome:R-HSA-72172 |
mRNA Splicing |
| Reactome:R-HSA-429947 |
Deadenylation of mRNA |
| Reactome:R-MMU-1640170 |
Cell Cycle |
| Reactome:R-MMU-69563 |
p53-Dependent G1 DNA Damage Response |
| Reactome:R-MMU-69239 |
Synthesis of DNA |
| Reactome:R-MMU-168256 |
Immune System |
| Reactome:R-MMU-389948 |
PD-1 signaling |
| Reactome:R-MMU-168249 |
Innate Immune System |
| Reactome:R-MMU-936964 |
Activation of IRF3, IRF7 mediated by TBK1, IKK (IKBKE) |
| Reactome:R-MMU-913531 |
Interferon Signaling |
| Reactome:R-MMU-877312 |
Regulation of IFNG signaling |
| Reactome:R-MMU-449147 |
Signaling by Interleukins |
| Reactome:R-MMU-912631 |
Regulation of signaling by CBL |
| Reactome:R-MMU-1170546 |
Prolactin receptor signaling |
| Reactome:R-MMU-73893 |
DNA Damage Bypass |
| Reactome:R-MMU-110320 |
Translesion Synthesis by POLH |
| Reactome:R-MMU-5693607 |
Processing of DNA double-strand break ends |
| Reactome:R-MMU-5696394 |
DNA Damage Recognition in GG-NER |
| Reactome:R-MMU-6781827 |
Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| Reactome:R-MMU-1430728 |
Metabolism |
| Reactome:R-MMU-556833 |
Metabolism of lipids |
| Reactome:R-MMU-8957322 |
Metabolism of steroids |
| Reactome:R-MMU-202131 |
Metabolism of nitric oxide: NOS3 activation and regulation |
| Reactome:R-MMU-8953854 |
Metabolism of RNA |
| Reactome:R-MMU-72163 |
pre-mRNA splicing |
| Reactome:R-MMU-429914 |
Deadenylation-dependent mRNA decay |
| Reactome:R-MMU-8866427 |
VLDLR internalisation and degradation |
| Reactome:R-MMU-9033241 |
Peroxisomal protein import |
| Reactome:R-MMU-5357801 |
Programmed Cell Death |
| Reactome:R-MMU-111463 |
SMAC (DIABLO) binds to IAPs |
| Reactome:R-MMU-5675482 |
Regulation of necroptotic cell death |
| Reactome:R-MMU-1234174 |
Cellular response to hypoxia |
| Reactome:R-MMU-2559580 |
Oxidative Stress Induced Senescence |
| Reactome:R-MMU-418990 |
Adherens junctions interactions |
| Reactome:R-MMU-3214847 |
HATs acetylate histones |
| Reactome:R-MMU-74160 |
Gene expression (Transcription) |
| Reactome:R-MMU-73857 |
RNA Polymerase II Transcription |
| Reactome:R-MMU-3700989 |
Transcriptional Regulation by TP53 |
| Reactome:R-MMU-5633007 |
Regulation of TP53 Activity |
| Reactome:R-MMU-6804756 |
Regulation of TP53 Activity through Phosphorylation |
| Reactome:R-MMU-212165 |
Epigenetic regulation of gene expression |
| Reactome:R-MMU-162582 |
Signaling Pathways |
| Reactome:R-MMU-190236 |
Signaling by FGFR |
| Reactome:R-MMU-5654726 |
Negative regulation of FGFR1 signaling |
| Reactome:R-MMU-5654727 |
Negative regulation of FGFR2 signaling |
| Reactome:R-MMU-6807004 |
Negative regulation of MET activity |
| Reactome:R-MMU-2173788 |
Downregulation of TGF-beta receptor signaling |
| Reactome:R-MMU-4641257 |
Degradation of AXIN |
| Reactome:R-MMU-5632684 |
Hedgehog 'on' state |
| Reactome:R-MMU-5673001 |
RAF/MAP kinase cascade |
| Reactome:R-MMU-198323 |
AKT phosphorylates targets in the cytosol |
| Reactome:R-MMU-6807070 |
PTEN Regulation |
| Reactome:R-MMU-9006927 |
Signaling by Non-Receptor Tyrosine Kinases |
| Reactome:R-MMU-5357956 |
TNFR1-induced NF-kappa-B signaling pathway |
| Reactome:R-MMU-3899300 |
SUMOylation of transcription cofactors |
| Reactome:R-MMU-4615885 |
SUMOylation of DNA replication proteins |
| Reactome:R-MMU-5689880 |
Ub-specific processing proteases |
| Reactome:R-MMU-8852135 |
Protein ubiquitination |
| Reactome:R-MMU-8856825 |
Cargo recognition for clathrin-mediated endocytosis |
| Reactome:R-RNO-72203 |
Processing of Capped Intron-Containing Pre-mRNA |
| Reactome:R-RNO-597592 |
Post-translational protein modification |
| Reactome:R-RNO-2990846 |
SUMOylation |
| Reactome:R-RNO-3108214 |
SUMOylation of DNA damage response and repair proteins |
| Reactome:R-RNO-5689896 |
Ovarian tumor domain proteases |
| Reactome:R-RNO-8953750 |
Transcriptional Regulation by E2F6 |
| Reactome:R-RNO-162582 |
Signaling Pathways |
| Reactome:R-RNO-4641257 |
Degradation of AXIN |
| Reactome:R-RNO-73887 |
Death Receptor Signaling |
| Reactome:R-RNO-5357786 |
TNFR1-induced proapoptotic signaling |
| Reactome:R-RNO-193704 |
p75 NTR receptor-mediated signalling |
| Reactome:R-RNO-205043 |
NRIF signals cell death from the nucleus |
| Reactome:R-RNO-209560 |
NF-kB is activated and signals survival |
| Reactome:R-RNO-193692 |
Regulated proteolysis of p75NTR |
| Reactome:R-RNO-382551 |
Transport of small molecules |
| Reactome:R-RNO-174824 |
Lipoprotein metabolism |
| Reactome:R-RNO-9609507 |
Protein localization |
| Reactome:R-RNO-73894 |
DNA Repair |
| Reactome:R-RNO-5693565 |
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
| Reactome:R-RNO-5693571 |
Nonhomologous End-Joining (NHEJ) |
| Reactome:R-RNO-6781823 |
Formation of TC-NER Pre-Incision Complex |
| Reactome:R-RNO-109606 |
Intrinsic Pathway for Apoptosis |
| Reactome:R-RNO-111469 |
SMAC, XIAP-regulated apoptotic response |
| Reactome:R-RNO-1280218 |
Adaptive Immune System |
| Reactome:R-RNO-168898 |
Toll-like Receptor Cascades |
| Reactome:R-RNO-937039 |
IRAK1 recruits IKK complex |
| Reactome:R-RNO-450321 |
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| Reactome:R-RNO-168181 |
Toll Like Receptor 7/8 (TLR7/8) Cascade |
| Reactome:R-RNO-975163 |
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| Reactome:R-RNO-168188 |
Toll Like Receptor TLR6:TLR2 Cascade |
| Reactome:R-RNO-168638 |
NOD1/2 Signaling Pathway |
| Reactome:R-RNO-5621481 |
C-type lectin receptors (CLRs) |
| Reactome:R-RNO-446652 |
Interleukin-1 family signaling |
| Reactome:R-SCE-6782210 |
Gap-filling DNA repair synthesis and ligation in TC-NER |
| Reactome:R-SCE-9609507 |
Protein localization |
| Reactome:R-SCE-597592 |
Post-translational protein modification |
| Reactome:R-SCE-3108232 |
SUMO E3 ligases SUMOylate target proteins |
| Reactome:R-SPO-9033241 |
Peroxisomal protein import |
| Reactome:R-SPO-3108214 |
SUMOylation of DNA damage response and repair proteins |
| Reactome:R-SSC-1257604 |
PI3K/AKT Signaling |
| Reactome:R-SSC-6811558 |
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling |
| Reactome:R-SSC-209543 |
p75NTR recruits signalling complexes |
| Reactome:R-SSC-168256 |
Immune System |
| Reactome:R-SSC-168898 |
Toll-like Receptor Cascades |
| Reactome:R-SSC-937039 |
IRAK1 recruits IKK complex |
| Reactome:R-SSC-450321 |
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| Reactome:R-SSC-168181 |
Toll Like Receptor 7/8 (TLR7/8) Cascade |
| Reactome:R-SSC-975163 |
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| Reactome:R-SSC-181438 |
Toll Like Receptor 2 (TLR2) Cascade |
| Reactome:R-SSC-2871837 |
FCERI mediated NF-kB activation |
| Reactome:R-SSC-449147 |
Signaling by Interleukins |
| Reactome:R-XTR-168249 |
Innate Immune System |
| Reactome:R-XTR-975871 |
MyD88 cascade initiated on plasma membrane |
| Reactome:R-XTR-450294 |
MAP kinase activation |
| Reactome:R-XTR-168181 |
Toll Like Receptor 7/8 (TLR7/8) Cascade |
| Reactome:R-XTR-975163 |
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| Reactome:R-XTR-5621481 |
C-type lectin receptors (CLRs) |
| Reactome:R-XTR-448424 |
Interleukin-17 signaling |
| Reactome:R-XTR-170834 |
Signaling by TGF-beta Receptor Complex |
| Reactome:R-XTR-1257604 |
PI3K/AKT Signaling |
| Reactome:R-XTR-209560 |
NF-kB is activated and signals survival |
| Reactome:R-XTR-5688426 |
Deubiquitination |
| Reactome:R-BTA-5689880 |
Ub-specific processing proteases |
| Reactome:R-BTA-8852135 |
Protein ubiquitination |
| Reactome:R-BTA-168249 |
Innate Immune System |
| Reactome:R-BTA-975871 |
MyD88 cascade initiated on plasma membrane |
| Reactome:R-BTA-450294 |
MAP kinase activation |
| Reactome:R-BTA-168181 |
Toll Like Receptor 7/8 (TLR7/8) Cascade |
| Reactome:R-BTA-975163 |
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| Reactome:R-BTA-181438 |
Toll Like Receptor 2 (TLR2) Cascade |
| Reactome:R-BTA-2871837 |
FCERI mediated NF-kB activation |
| Reactome:R-BTA-1280215 |
Cytokine Signaling in Immune system |
| Reactome:R-BTA-9020702 |
Interleukin-1 signaling |
| Reactome:R-BTA-72203 |
Processing of Capped Intron-Containing Pre-mRNA |
| Reactome:R-BTA-202131 |
Metabolism of nitric oxide: NOS3 activation and regulation |
| Reactome:R-BTA-73894 |
DNA Repair |
| Reactome:R-BTA-5693565 |
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
| Reactome:R-BTA-5693571 |
Nonhomologous End-Joining (NHEJ) |
| Reactome:R-BTA-6781823 |
Formation of TC-NER Pre-Incision Complex |
| Reactome:R-BTA-162582 |
Signaling Pathways |
| Reactome:R-BTA-1257604 |
PI3K/AKT Signaling |
| Reactome:R-BTA-6811558 |
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling |
| Reactome:R-BTA-8948751 |
Regulation of PTEN stability and activity |
| Reactome:R-BTA-204998 |
Cell death signalling via NRAGE, NRIF and NADE |
| Reactome:R-BTA-193639 |
p75NTR signals via NF-kB |
| Reactome:R-CEL-168256 |
Immune System |
| Reactome:R-CEL-392499 |
Metabolism of proteins |
| Reactome:R-CEL-597592 |
Post-translational protein modification |
| Reactome:R-CEL-5688426 |
Deubiquitination |
| Reactome:R-CEL-6781823 |
Formation of TC-NER Pre-Incision Complex |
| Reactome:R-CEL-5673000 |
RAF activation |
| Reactome:R-CEL-382551 |
Transport of small molecules |
| Reactome:R-CFA-8953897 |
Cellular responses to stimuli |
| Reactome:R-CFA-2262752 |
Cellular responses to stress |
| Reactome:R-CFA-2559583 |
Cellular Senescence |
| Reactome:R-CFA-446728 |
Cell junction organization |
| Reactome:R-CFA-937061 |
TRIF (TICAM1)-mediated TLR4 signaling |
| Reactome:R-CFA-5689880 |
Ub-specific processing proteases |
| Reactome:R-CFA-1640170 |
Cell Cycle |
| Reactome:R-CFA-69563 |
p53-Dependent G1 DNA Damage Response |
| Reactome:R-CFA-74160 |
Gene expression (Transcription) |
| Reactome:R-CFA-212436 |
Generic Transcription Pathway |
| Reactome:R-CFA-3700989 |
Transcriptional Regulation by TP53 |
| Reactome:R-CFA-5633007 |
Regulation of TP53 Activity |
| Reactome:R-CFA-6804756 |
Regulation of TP53 Activity through Phosphorylation |
| Reactome:R-DRE-162582 |
Signaling Pathways |
| Reactome:R-DRE-1227986 |
Signaling by ERBB2 |
| Reactome:R-DRE-1358803 |
Downregulation of ERBB2:ERBB3 signaling |
| Reactome:R-DRE-9006925 |
Intracellular signaling by second messengers |
| Reactome:R-DRE-6807070 |
PTEN Regulation |
| Reactome:R-DRE-193704 |
p75 NTR receptor-mediated signalling |
| Reactome:R-DRE-193639 |
p75NTR signals via NF-kB |
| Reactome:R-DRE-5693606 |
DNA Double Strand Break Response |
| Reactome:R-DRE-212436 |
Generic Transcription Pathway |
| Reactome:R-DRE-3700989 |
Transcriptional Regulation by TP53 |
| Reactome:R-DRE-6806003 |
Regulation of TP53 Expression and Degradation |
| Reactome:R-DRE-8939243 |
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known |
| Reactome:R-DRE-8953897 |
Cellular responses to stimuli |
| Reactome:R-DRE-2559580 |
Oxidative Stress Induced Senescence |
| Reactome:R-DRE-69620 |
Cell Cycle Checkpoints |
| Reactome:R-DRE-69541 |
Stabilization of p53 |
| Reactome:R-DRE-418990 |
Adherens junctions interactions |
| Reactome:R-DRE-70268 |
Pyruvate metabolism |
| Reactome:R-DRE-4570464 |
SUMOylation of RNA binding proteins |
| Reactome:R-DRE-4085377 |
SUMOylation of SUMOylation proteins |
| Reactome:R-DRE-168256 |
Immune System |
| Reactome:R-DRE-168898 |
Toll-like Receptor Cascades |
| Reactome:R-DRE-937039 |
IRAK1 recruits IKK complex |
| Reactome:R-DRE-450321 |
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| Reactome:R-DRE-168181 |
Toll Like Receptor 7/8 (TLR7/8) Cascade |
| Reactome:R-DRE-975163 |
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| Reactome:R-DRE-166058 |
MyD88:MAL(TIRAP) cascade initiated on plasma membrane |
| Reactome:R-DRE-181438 |
Toll Like Receptor 2 (TLR2) Cascade |
| Reactome:R-DRE-9020702 |
Interleukin-1 signaling |
| Reactome:R-DDI-5696398 |
Nucleotide Excision Repair |
| Reactome:R-DDI-6781827 |
Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| Reactome:R-DDI-392499 |
Metabolism of proteins |
| Reactome:R-DDI-2262752 |
Cellular responses to stress |
| Reactome:R-DME-4839726 |
Chromatin organization |
| Reactome:R-DME-8951664 |
Neddylation |
| Reactome:R-DME-162582 |
Signaling Pathways |
| Reactome:R-DME-157118 |
Signaling by NOTCH |
| Reactome:R-DME-2122948 |
Activated NOTCH1 Transmits Signal to the Nucleus |
| Reactome:R-DME-5358346 |
Hedgehog ligand biogenesis |
| Reactome:R-DME-6807070 |
PTEN Regulation |
| Reactome:R-DME-8953897 |
Cellular responses to stimuli |
| Reactome:R-DME-8878171 |
Transcriptional regulation by RUNX1 |
| Reactome:R-DME-390146 |
Hippo/Warts pathway |
| Reactome:R-GGA-1428517 |
Aerobic respiration and respiratory electron transport |
| Reactome:R-GGA-8852135 |
Protein ubiquitination |
| Reactome:R-HSA-199991 |
Membrane Trafficking |
| Reactome:R-HSA-1266738 |
Developmental Biology |
| Reactome:R-HSA-373752 |
Netrin-1 signaling |
| Reactome:R-HSA-421270 |
Cell-cell junction organization |
| Reactome:R-HSA-1500620 |
Meiosis |
| Reactome:R-HSA-71387 |
Carbohydrate metabolism |
| Reactome:R-HSA-556833 |
Metabolism of lipids |
| Reactome:R-HSA-203754 |
NOSIP mediated eNOS trafficking |
| Reactome:R-HSA-70268 |
Pyruvate metabolism |
| Reactome:R-HSA-5357769 |
Caspase activation via extrinsic apoptotic signalling pathway |
| Reactome:R-HSA-111459 |
Activation of caspases through apoptosome-mediated cleavage |
| Reactome:R-HSA-75153 |
Apoptotic execution phase |
| Reactome:R-HSA-5213460 |
RIPK1-mediated regulated necrosis |
| Reactome:R-HSA-73893 |
DNA Damage Bypass |
| Reactome:R-HSA-110320 |
Translesion Synthesis by POLH |
| Reactome:R-HSA-5693565 |
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
| Reactome:R-HSA-5685942 |
HDR through Homologous Recombination (HRR) |
| Reactome:R-HSA-5693568 |
Resolution of D-loop Structures through Holliday Junction Intermediates |
| Reactome:R-HSA-5693571 |
Nonhomologous End-Joining (NHEJ) |
| Reactome:R-HSA-5696395 |
Formation of Incision Complex in GG-NER |
| Reactome:R-HSA-6781823 |
Formation of TC-NER Pre-Incision Complex |
| Reactome:R-HSA-9006934 |
Signaling by Receptor Tyrosine Kinases |
| Reactome:R-HSA-5654736 |
Signaling by FGFR1 |
| Reactome:R-HSA-1295596 |
Spry regulation of FGF signaling |
| Reactome:R-HSA-5654741 |
Signaling by FGFR3 |
| Reactome:R-HSA-1433559 |
Regulation of KIT signaling |
| Reactome:R-HSA-6806834 |
Signaling by MET |
| Reactome:R-HSA-2173788 |
Downregulation of TGF-beta receptor signaling |
| Reactome:R-HSA-2173795 |
Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| Reactome:R-HSA-2122947 |
NOTCH1 Intracellular Domain Regulates Transcription |
| Reactome:R-HSA-9013694 |
Signaling by NOTCH4 |
| Reactome:R-HSA-195721 |
Signaling by WNT |
| Reactome:R-HSA-4641257 |
Degradation of AXIN |
| Reactome:R-HSA-5358346 |
Hedgehog ligand biogenesis |
| Reactome:R-HSA-5610783 |
Degradation of GLI2 by the proteasome |
| Reactome:R-HSA-9006931 |
Signaling by Nuclear Receptors |
| Reactome:R-HSA-5673000 |
RAF activation |
| Reactome:R-HSA-5658442 |
Regulation of RAS by GAPs |
| Reactome:R-HSA-8948751 |
Regulation of PTEN stability and activity |
| Reactome:R-HSA-8849469 |
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 |
| Reactome:R-HSA-209560 |
NF-kB is activated and signals survival |
| Reactome:R-HSA-2262752 |
Cellular responses to stress |
| Reactome:R-HSA-1234176 |
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha |
| Reactome:R-HSA-2559583 |
Cellular Senescence |
| Reactome:R-HSA-1640170 |
Cell Cycle |
| Reactome:R-HSA-69563 |
p53-Dependent G1 DNA Damage Response |
| Reactome:R-HSA-68949 |
Orc1 removal from chromatin |
| Reactome:R-HSA-453274 |
Mitotic G2-G2/M phases |
| Reactome:R-HSA-3899300 |
SUMOylation of transcription cofactors |
| Reactome:R-HSA-4615885 |
SUMOylation of DNA replication proteins |
| Reactome:R-HSA-5689880 |
Ub-specific processing proteases |
| Reactome:R-HSA-8852135 |
Protein ubiquitination |
| Reactome:R-HSA-977225 |
Amyloid fiber formation |
| Reactome:R-HSA-5637815 |
Signaling by Ligand-Responsive EGFR Variants in Cancer |
| Reactome:R-HSA-1839124 |
FGFR1 mutant receptor activation |
| Reactome:R-HSA-2644602 |
Signaling by NOTCH1 PEST Domain Mutants in Cancer |
| Reactome:R-HSA-2644605 |
FBXW7 Mutants and NOTCH1 in Cancer |
| Reactome:R-HSA-5362768 |
Hh mutants are degraded by ERAD |
| Reactome:R-HSA-6802946 |
Signaling by moderate kinase activity BRAF mutants |
| Reactome:R-HSA-162906 |
HIV Infection |
| Reactome:R-HSA-180585 |
Vif-mediated degradation of APOBEC3G |
| Reactome:R-HSA-8875360 |
InlB-mediated entry of Listeria monocytogenes into host cell |
| Reactome:R-HSA-69306 |
DNA Replication |
| Reactome:R-HSA-9033241 |
Peroxisomal protein import |
| Reactome:R-HSA-3214847 |
HATs acetylate histones |
| Reactome:R-HSA-6804115 |
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain |
| Reactome:R-HSA-6804760 |
Regulation of TP53 Activity through Methylation |
| Reactome:R-HSA-8939902 |
Regulation of RUNX2 expression and activity |
| Reactome:R-HSA-212165 |
Epigenetic regulation of gene expression |
| Reactome:R-HSA-202403 |
TCR signaling |
| Reactome:R-HSA-202424 |
Downstream TCR signaling |
| Reactome:R-HSA-937042 |
IRAK2 mediated activation of TAK1 complex |
| Reactome:R-HSA-450302 |
activated TAK1 mediates p38 MAPK activation |
| Reactome:R-HSA-168164 |
Toll Like Receptor 3 (TLR3) Cascade |
| Reactome:R-HSA-9014325 |
TICAM1,TRAF6-dependent induction of TAK1 complex |
| Reactome:R-HSA-975138 |
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation |
| Reactome:R-HSA-168138 |
Toll Like Receptor 9 (TLR9) Cascade |
| Reactome:R-HSA-166166 |
MyD88-independent TLR4 cascade |
| Reactome:R-HSA-168188 |
Toll Like Receptor TLR6:TLR2 Cascade |
| Reactome:R-HSA-168643 |
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways |
| Reactome:R-HSA-168928 |
DDX58/IFIH1-mediated induction of interferon-alpha/beta |
| Reactome:R-HSA-933542 |
TRAF6 mediated NF-kB activation |
| Reactome:R-HSA-1606341 |
IRF3 mediated activation of type 1 IFN |
| Reactome:R-HSA-2871796 |
FCERI mediated MAPK activation |
| Reactome:R-HSA-5621481 |
C-type lectin receptors (CLRs) |
| Reactome:R-HSA-913531 |
Interferon Signaling |
| Reactome:R-HSA-449147 |
Signaling by Interleukins |
| Reactome:R-HSA-912631 |
Regulation of signaling by CBL |
| Reactome:R-HSA-72203 |
Processing of Capped Intron-Containing Pre-mRNA |
| Reactome:R-HSA-72187 |
mRNA 3'-end processing |
| Reactome:R-HSA-429914 |
Deadenylation-dependent mRNA decay |
| Reactome:R-MMU-69580 |
p53-Dependent G1/S DNA damage checkpoint |
| Reactome:R-MMU-69601 |
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A |
| Reactome:R-MMU-68949 |
Orc1 removal from chromatin |
| Reactome:R-MMU-453274 |
Mitotic G2-G2/M phases |
| Reactome:R-MMU-8854050 |
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis |
| Reactome:R-MMU-388841 |
Costimulation by the CD28 family |
| Reactome:R-MMU-166016 |
Toll Like Receptor 4 (TLR4) Cascade |
| Reactome:R-MMU-937061 |
TRIF (TICAM1)-mediated TLR4 signaling |
| Reactome:R-MMU-1280215 |
Cytokine Signaling in Immune system |
| Reactome:R-MMU-877300 |
Interferon gamma signaling |
| Reactome:R-MMU-9020702 |
Interleukin-1 signaling |
| Reactome:R-MMU-512988 |
Interleukin-3, Interleukin-5 and GM-CSF signaling |
| Reactome:R-MMU-1059683 |
Interleukin-6 signaling |
| Reactome:R-MMU-5656169 |
Termination of translesion DNA synthesis |
| Reactome:R-MMU-5693606 |
DNA Double Strand Break Response |
| Reactome:R-MMU-5693567 |
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| Reactome:R-MMU-5685938 |
HDR through Single Strand Annealing (SSA) |
| Reactome:R-MMU-5696399 |
Global Genome Nucleotide Excision Repair (GG-NER) |
| Reactome:R-MMU-6782210 |
Gap-filling DNA repair synthesis and ligation in TC-NER |
| Reactome:R-MMU-6783310 |
Fanconi Anemia Pathway |
| Reactome:R-MMU-203754 |
NOSIP mediated eNOS trafficking |
| Reactome:R-MMU-70268 |
Pyruvate metabolism |
| Reactome:R-MMU-72172 |
mRNA Splicing |
| Reactome:R-MMU-8964043 |
Plasma lipoprotein clearance |
| Reactome:R-MMU-202733 |
Cell surface interactions at the vascular wall |
| Reactome:R-MMU-140534 |
Ligand-dependent caspase activation |
| Reactome:R-MMU-109606 |
Intrinsic Pathway for Apoptosis |
| Reactome:R-MMU-111469 |
SMAC, XIAP-regulated apoptotic response |
| Reactome:R-MMU-111465 |
Apoptotic cleavage of cellular proteins |
| Reactome:R-MMU-5213460 |
RIPK1-mediated regulated necrosis |
| Reactome:R-MMU-2559585 |
Oncogene Induced Senescence |
| Reactome:R-MMU-421270 |
Cell-cell junction organization |
| Reactome:R-MMU-3247509 |
Chromatin modifying enzymes |
| Reactome:R-MMU-2173795 |
Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| Reactome:R-MMU-6791312 |
TP53 Regulates Transcription of Cell Cycle Genes |
| Reactome:R-MMU-6804757 |
Regulation of TP53 Degradation |
| Reactome:R-MMU-182971 |
EGFR downregulation |
| Reactome:R-MMU-5654743 |
Signaling by FGFR4 |
| Reactome:R-MMU-5654733 |
Negative regulation of FGFR4 signaling |
| Reactome:R-MMU-1227986 |
Signaling by ERBB2 |
| Reactome:R-MMU-1358803 |
Downregulation of ERBB2:ERBB3 signaling |
| Reactome:R-MMU-2173789 |
TGF-beta receptor signaling activates SMADs |
| Reactome:R-MMU-195253 |
Degradation of beta-catenin by the destruction complex |
| Reactome:R-MMU-4641258 |
Degradation of DVL |
| Reactome:R-MMU-5358346 |
Hedgehog ligand biogenesis |
| Reactome:R-MMU-5610780 |
Degradation of GLI1 by the proteasome |
| Reactome:R-MMU-5684996 |
ERK1/ERK2 pathway |
| Reactome:R-MMU-5675221 |
Negative regulation of MAPK pathway |
| Reactome:R-MMU-1257604 |
PI3K/AKT Signaling |
| Reactome:R-MMU-8948751 |
Regulation of PTEN stability and activity |
| Reactome:R-MMU-75893 |
TNF signaling |
| Reactome:R-MMU-5357905 |
Regulation of TNFR1 signaling |
| Reactome:R-MMU-3232118 |
SUMOylation of transcription factors |
| Reactome:R-MMU-4085377 |
SUMOylation of SUMOylation proteins |
| Reactome:R-MMU-5689603 |
UCH proteinases |
| Reactome:R-MMU-8856828 |
Clathrin-mediated endocytosis |
| Reactome:R-RNO-70268 |
Pyruvate metabolism |
| Reactome:R-RNO-392499 |
Metabolism of proteins |
| Reactome:R-RNO-3899300 |
SUMOylation of transcription cofactors |
| Reactome:R-RNO-5689880 |
Ub-specific processing proteases |
| Reactome:R-RNO-8852135 |
Protein ubiquitination |
| Reactome:R-RNO-6807070 |
PTEN Regulation |
| Reactome:R-RNO-209543 |
p75NTR recruits signalling complexes |
| Reactome:R-RNO-5693607 |
Processing of DNA double-strand break ends |
| Reactome:R-RNO-6781827 |
Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| Reactome:R-RNO-111471 |
Apoptotic factor-mediated response |
| Reactome:R-RNO-168256 |
Immune System |
| Reactome:R-RNO-389948 |
PD-1 signaling |
| Reactome:R-RNO-168249 |
Innate Immune System |
| Reactome:R-RNO-975871 |
MyD88 cascade initiated on plasma membrane |
| Reactome:R-RNO-450294 |
MAP kinase activation |
| Reactome:R-RNO-168176 |
Toll Like Receptor 5 (TLR5) Cascade |
| Reactome:R-RNO-975144 |
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation |
| Reactome:R-RNO-166016 |
Toll Like Receptor 4 (TLR4) Cascade |
| Reactome:R-RNO-937061 |
TRIF (TICAM1)-mediated TLR4 signaling |
| Reactome:R-RNO-168179 |
Toll Like Receptor TLR1:TLR2 Cascade |
| Reactome:R-RNO-168643 |
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways |
| Reactome:R-RNO-2454202 |
Fc epsilon receptor (FCERI) signaling |
| Reactome:R-RNO-449147 |
Signaling by Interleukins |
| Reactome:R-RNO-448424 |
Interleukin-17 signaling |
| Reactome:R-SCE-5696398 |
Nucleotide Excision Repair |
| Reactome:R-SCE-6782135 |
Dual incision in TC-NER |
| Reactome:R-SCE-72766 |
Translation |
| Reactome:R-SCE-2990846 |
SUMOylation |
| Reactome:R-SPO-8953854 |
Metabolism of RNA |
| Reactome:R-SPO-6781827 |
Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| Reactome:R-SSC-9006925 |
Intracellular signaling by second messengers |
| Reactome:R-SSC-199418 |
Negative regulation of the PI3K/AKT network |
| Reactome:R-SSC-193639 |
p75NTR signals via NF-kB |
| Reactome:R-SSC-168249 |
Innate Immune System |
| Reactome:R-SSC-975871 |
MyD88 cascade initiated on plasma membrane |
| Reactome:R-SSC-450294 |
MAP kinase activation |
| Reactome:R-SSC-168176 |
Toll Like Receptor 5 (TLR5) Cascade |
| Reactome:R-SSC-975144 |
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation |
| Reactome:R-SSC-166016 |
Toll Like Receptor 4 (TLR4) Cascade |
| Reactome:R-SSC-937061 |
TRIF (TICAM1)-mediated TLR4 signaling |
| Reactome:R-SSC-937072 |
TRAF6-mediated induction of TAK1 complex within TLR4 complex |
| Reactome:R-SSC-5607764 |
CLEC7A (Dectin-1) signaling |
| Reactome:R-SSC-1280215 |
Cytokine Signaling in Immune system |
| Reactome:R-SSC-9020702 |
Interleukin-1 signaling |
| Reactome:R-SSC-448424 |
Interleukin-17 signaling |
| Reactome:R-SSC-392499 |
Metabolism of proteins |
| Reactome:R-SSC-5688426 |
Deubiquitination |
| Reactome:R-XTR-2173796 |
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| Reactome:R-XTR-202403 |
TCR signaling |
| Reactome:R-XTR-202424 |
Downstream TCR signaling |
| Reactome:R-XTR-168142 |
Toll Like Receptor 10 (TLR10) Cascade |
| Reactome:R-XTR-168176 |
Toll Like Receptor 5 (TLR5) Cascade |
| Reactome:R-XTR-166016 |
Toll Like Receptor 4 (TLR4) Cascade |
| Reactome:R-XTR-937061 |
TRIF (TICAM1)-mediated TLR4 signaling |
| Reactome:R-XTR-168188 |
Toll Like Receptor TLR6:TLR2 Cascade |
| Reactome:R-XTR-2454202 |
Fc epsilon receptor (FCERI) signaling |
| Reactome:R-XTR-1280215 |
Cytokine Signaling in Immune system |
| Reactome:R-XTR-449147 |
Signaling by Interleukins |
| Reactome:R-XTR-9006936 |
Signaling by TGFB family members |
| Reactome:R-XTR-9006925 |
Intracellular signaling by second messengers |
| Reactome:R-XTR-6807070 |
PTEN Regulation |
| Reactome:R-XTR-73887 |
Death Receptor Signaling |
| Reactome:R-XTR-209543 |
p75NTR recruits signalling complexes |
| Reactome:R-XTR-597592 |
Post-translational protein modification |
| Reactome:R-XTR-5689896 |
Ovarian tumor domain proteases |
| Reactome:R-BTA-392499 |
Metabolism of proteins |
| Reactome:R-BTA-3108232 |
SUMO E3 ligases SUMOylate target proteins |
| Reactome:R-BTA-5688426 |
Deubiquitination |
| Reactome:R-BTA-8866654 |
E3 ubiquitin ligases ubiquitinate target proteins |
| Reactome:R-BTA-1280218 |
Adaptive Immune System |
| Reactome:R-BTA-937042 |
IRAK2 mediated activation of TAK1 complex |
| Reactome:R-BTA-450302 |
activated TAK1 mediates p38 MAPK activation |
| Reactome:R-BTA-975138 |
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation |
| Reactome:R-BTA-168138 |
Toll Like Receptor 9 (TLR9) Cascade |
| Reactome:R-BTA-166166 |
MyD88-independent TLR4 cascade |
| Reactome:R-BTA-168188 |
Toll Like Receptor TLR6:TLR2 Cascade |
| Reactome:R-BTA-168643 |
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways |
| Reactome:R-BTA-3134975 |
Regulation of innate immune responses to cytosolic DNA |
| Reactome:R-BTA-5621481 |
C-type lectin receptors (CLRs) |
| Reactome:R-BTA-446652 |
Interleukin-1 family signaling |
| Reactome:R-BTA-8953854 |
Metabolism of RNA |
| Reactome:R-BTA-72163 |
pre-mRNA splicing |
| Reactome:R-BTA-5693606 |
DNA Double Strand Break Response |
| Reactome:R-BTA-5693567 |
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| Reactome:R-BTA-6782210 |
Gap-filling DNA repair synthesis and ligation in TC-NER |
| Reactome:R-BTA-195721 |
Signaling by WNT |
| Reactome:R-BTA-73887 |
Death Receptor Signaling |
| Reactome:R-BTA-193704 |
p75 NTR receptor-mediated signalling |
| Reactome:R-BTA-205043 |
NRIF signals cell death from the nucleus |
| Reactome:R-BTA-209560 |
NF-kB is activated and signals survival |
| Reactome:R-BTA-193692 |
Regulated proteolysis of p75NTR |
| Reactome:R-CEL-109582 |
Hemostasis |
| Reactome:R-CEL-72172 |
mRNA Splicing |
| Reactome:R-CEL-5689880 |
Ub-specific processing proteases |
| Reactome:R-CEL-5696398 |
Nucleotide Excision Repair |
| Reactome:R-CEL-6782210 |
Gap-filling DNA repair synthesis and ligation in TC-NER |
| Reactome:R-CEL-162582 |
Signaling Pathways |
| Reactome:R-CEL-5684996 |
ERK1/ERK2 pathway |
| Reactome:R-CEL-5675221 |
Negative regulation of MAPK pathway |
| Reactome:R-CEL-1257604 |
PI3K/AKT Signaling |
| Reactome:R-CEL-8948751 |
Regulation of PTEN stability and activity |
| Reactome:R-CFA-2559580 |
Oxidative Stress Induced Senescence |
| Reactome:R-CFA-418990 |
Adherens junctions interactions |
| Reactome:R-CFA-168249 |
Innate Immune System |
| Reactome:R-CFA-392499 |
Metabolism of proteins |
| Reactome:R-CFA-5688426 |
Deubiquitination |
| Reactome:R-CFA-112316 |
Neuronal System |
| Reactome:R-CFA-399719 |
Trafficking of AMPA receptors |
| Reactome:R-CFA-69615 |
G1/S DNA Damage Checkpoints |
| Reactome:R-CFA-6804760 |
Regulation of TP53 Activity through Methylation |
| Reactome:R-CFA-8878159 |
Transcriptional regulation by RUNX3 |
| Reactome:R-DRE-5358346 |
Hedgehog ligand biogenesis |
| Reactome:R-DRE-209560 |
NF-kB is activated and signals survival |
| Reactome:R-DRE-73894 |
DNA Repair |
| Reactome:R-DRE-5693565 |
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
| Reactome:R-DRE-6804757 |
Regulation of TP53 Degradation |
| Reactome:R-DRE-8878171 |
Transcriptional regulation by RUNX1 |
| Reactome:R-DRE-8941858 |
Regulation of RUNX3 expression and activity |
| Reactome:R-DRE-8953750 |
Transcriptional Regulation by E2F6 |
| Reactome:R-DRE-2262752 |
Cellular responses to stress |
| Reactome:R-DRE-2559583 |
Cellular Senescence |
| Reactome:R-DRE-69580 |
p53-Dependent G1/S DNA damage checkpoint |
| Reactome:R-DRE-382556 |
ABC-family proteins mediated transport |
| Reactome:R-DRE-446728 |
Cell junction organization |
| Reactome:R-DRE-1430728 |
Metabolism |
| Reactome:R-DRE-556833 |
Metabolism of lipids |
| Reactome:R-DRE-8957322 |
Metabolism of steroids |
| Reactome:R-DRE-1428517 |
Aerobic respiration and respiratory electron transport |
| Reactome:R-DRE-72766 |
Translation |
| Reactome:R-DRE-2990846 |
SUMOylation |
| Reactome:R-DRE-3108214 |
SUMOylation of DNA damage response and repair proteins |
| Reactome:R-DRE-4090294 |
SUMOylation of intracellular receptors |
| Reactome:R-DRE-4755510 |
SUMOylation of immune response proteins |
| Reactome:R-DRE-5689896 |
Ovarian tumor domain proteases |
| Reactome:R-DRE-388841 |
Costimulation by the CD28 family |
| Reactome:R-DRE-168142 |
Toll Like Receptor 10 (TLR10) Cascade |
| Reactome:R-DRE-445989 |
TAK1-dependent IKK and NF-kappa-B activation |
| Reactome:R-DRE-975138 |
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation |
| Reactome:R-DRE-168138 |
Toll Like Receptor 9 (TLR9) Cascade |
| Reactome:R-DRE-937061 |
TRIF (TICAM1)-mediated TLR4 signaling |
| Reactome:R-DRE-168188 |
Toll Like Receptor TLR6:TLR2 Cascade |
| Reactome:R-DRE-168638 |
NOD1/2 Signaling Pathway |
| Reactome:R-DRE-446652 |
Interleukin-1 family signaling |
| Reactome:R-DRE-448424 |
Interleukin-17 signaling |
| Reactome:R-DDI-6782135 |
Dual incision in TC-NER |
| Reactome:R-DDI-8953897 |
Cellular responses to stimuli |
| Reactome:R-DDI-9033241 |
Peroxisomal protein import |
| Reactome:R-DDI-8953854 |
Metabolism of RNA |
| Reactome:R-DME-3214847 |
HATs acetylate histones |
| Reactome:R-DME-392499 |
Metabolism of proteins |
| Reactome:R-DME-2990846 |
SUMOylation |
| Reactome:R-DME-3899300 |
SUMOylation of transcription cofactors |
| Reactome:R-DME-9006925 |
Intracellular signaling by second messengers |
| Reactome:R-DME-2262752 |
Cellular responses to stress |
| Reactome:R-DME-74160 |
Gene expression (Transcription) |
| Reactome:R-DME-73857 |
RNA Polymerase II Transcription |
| Reactome:R-DME-5252538 |
Drosophila signaling pathways |
| Reactome:R-GGA-1430728 |
Metabolism |
| Reactome:R-GGA-70268 |
Pyruvate metabolism |
| Reactome:R-GGA-392499 |
Metabolism of proteins |
| Reactome:R-GGA-8866654 |
E3 ubiquitin ligases ubiquitinate target proteins |
| Reactome:R-GGA-3247509 |
Chromatin modifying enzymes |
| Reactome:R-HSA-8866427 |
VLDLR internalisation and degradation |
| Reactome:R-HSA-8856828 |
Clathrin-mediated endocytosis |
| Reactome:R-HSA-9010553 |
Regulation of expression of SLITs and ROBOs |
| Reactome:R-HSA-1500931 |
Cell-Cell communication |
| Reactome:R-HSA-109582 |
Hemostasis |
| Reactome:R-HSA-210991 |
Basigin interactions |
| Reactome:R-HSA-1221632 |
Meiotic synapsis |
| Reactome:R-HSA-3322077 |
Glycogen synthesis |
| Reactome:R-HSA-1428517 |
Aerobic respiration and respiratory electron transport |
| Reactome:R-HSA-5357801 |
Programmed Cell Death |
| Reactome:R-HSA-111461 |
Cytochrome c-mediated apoptotic response |
| Reactome:R-HSA-111463 |
SMAC (DIABLO) binds to IAPs |
| Reactome:R-HSA-110313 |
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template |
| Reactome:R-HSA-5693606 |
DNA Double Strand Break Response |
| Reactome:R-HSA-5693567 |
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| Reactome:R-HSA-5685938 |
HDR through Single Strand Annealing (SSA) |
| Reactome:R-HSA-5696399 |
Global Genome Nucleotide Excision Repair (GG-NER) |
| Reactome:R-HSA-6782210 |
Gap-filling DNA repair synthesis and ligation in TC-NER |
| Reactome:R-HSA-6783310 |
Fanconi Anemia Pathway |
| Reactome:R-HSA-182971 |
EGFR downregulation |
| Reactome:R-HSA-5654743 |
Signaling by FGFR4 |
| Reactome:R-HSA-5654733 |
Negative regulation of FGFR4 signaling |
| Reactome:R-HSA-1358803 |
Downregulation of ERBB2:ERBB3 signaling |
| Reactome:R-HSA-170834 |
Signaling by TGF-beta Receptor Complex |
| Reactome:R-HSA-2173793 |
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| Reactome:R-HSA-1980143 |
Signaling by NOTCH1 |
| Reactome:R-HSA-195253 |
Degradation of beta-catenin by the destruction complex |
| Reactome:R-HSA-3769402 |
Deactivation of the beta-catenin transactivating complex |
| Reactome:R-HSA-5610787 |
Hedgehog 'off' state |
| Reactome:R-HSA-5632684 |
Hedgehog 'on' state |
| Reactome:R-HSA-5684996 |
ERK1/ERK2 pathway |
| Reactome:R-HSA-5675221 |
Negative regulation of MAPK pathway |
| Reactome:R-HSA-1257604 |
PI3K/AKT Signaling |
| Reactome:R-HSA-6811558 |
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling |
| Reactome:R-HSA-8848021 |
Signaling by PTK6 |
| Reactome:R-HSA-5357956 |
TNFR1-induced NF-kappa-B signaling pathway |
| Reactome:R-HSA-193639 |
p75NTR signals via NF-kB |
| Reactome:R-HSA-1234174 |
Cellular response to hypoxia |
| Reactome:R-HSA-2559580 |
Oxidative Stress Induced Senescence |
| Reactome:R-HSA-112316 |
Neuronal System |
| Reactome:R-HSA-399719 |
Trafficking of AMPA receptors |
| Reactome:R-HSA-69615 |
G1/S DNA Damage Checkpoints |
| Reactome:R-HSA-349425 |
Autodegradation of the E3 ubiquitin ligase COP1 |
| Reactome:R-HSA-69278 |
Cell Cycle, Mitotic |
| Reactome:R-HSA-69275 |
G2/M Transition |
| Reactome:R-HSA-72766 |
Translation |
| Reactome:R-HSA-3108232 |
SUMO E3 ligases SUMOylate target proteins |
| Reactome:R-HSA-4551638 |
SUMOylation of chromatin organization proteins |
| Reactome:R-HSA-3232142 |
SUMOylation of ubiquitinylation proteins |
| Reactome:R-HSA-5688426 |
Deubiquitination |
| Reactome:R-HSA-8866654 |
E3 ubiquitin ligases ubiquitinate target proteins |
| Reactome:R-HSA-8951664 |
Neddylation |
| Reactome:R-HSA-381119 |
Unfolded Protein Response (UPR) |
| Reactome:R-HSA-381038 |
XBP1(S) activates chaperone genes |
| Reactome:R-HSA-5663202 |
Diseases of signal transduction by growth factor receptors and second messengers |
| Reactome:R-HSA-5637812 |
Signaling by EGFRvIII in Cancer |
| Reactome:R-HSA-1226099 |
Signaling by FGFR in disease |
| Reactome:R-HSA-2894858 |
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer |
| Reactome:R-HSA-6802949 |
Signaling by RAS mutants |
| Reactome:R-HSA-6802952 |
Signaling by BRAF and RAF1 fusions |
| Reactome:R-HSA-8876384 |
Listeria monocytogenes entry into host cells |
| Reactome:R-HSA-5602358 |
Defects in Toll-like Receptor Cascades |
| Reactome:R-HSA-5602571 |
TRAF3 deficiency - HSE |
| Reactome:R-HSA-9609507 |
Protein localization |
| Reactome:R-HSA-4839726 |
Chromatin organization |
| Reactome:R-HSA-212436 |
Generic Transcription Pathway |
| Reactome:R-HSA-3700989 |
Transcriptional Regulation by TP53 |
| Reactome:R-HSA-5633007 |
Regulation of TP53 Activity |
| Reactome:R-HSA-6804756 |
Regulation of TP53 Activity through Phosphorylation |
| Reactome:R-HSA-8878159 |
Transcriptional regulation by RUNX3 |
| Reactome:R-HSA-8953750 |
Transcriptional Regulation by E2F6 |
| Reactome:R-HSA-168256 |
Immune System |
| Reactome:R-HSA-389948 |
PD-1 signaling |
| Reactome:R-HSA-168249 |
Innate Immune System |
| Reactome:R-HSA-975871 |
MyD88 cascade initiated on plasma membrane |
| Reactome:R-HSA-450294 |
MAP kinase activation |
| Reactome:R-HSA-168927 |
TICAM1, RIP1-mediated IKK complex recruitment |
| Reactome:R-HSA-168181 |
Toll Like Receptor 7/8 (TLR7/8) Cascade |
| Reactome:R-HSA-975163 |
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| Reactome:R-HSA-936964 |
Activation of IRF3, IRF7 mediated by TBK1, IKK (IKBKE) |
| Reactome:R-HSA-181438 |
Toll Like Receptor 2 (TLR2) Cascade |
| Reactome:R-HSA-1834949 |
Cytosolic sensors of pathogen-associated DNA |
| Reactome:R-HSA-1834941 |
STING mediated induction of host immune responses |
| Reactome:R-HSA-2871837 |
FCERI mediated NF-kB activation |
| Reactome:R-HSA-6783589 |
Interleukin-6 family signaling |
| Reactome:R-HSA-5668541 |
TNFR2 non-canonical NF-kB pathway |
| Reactome:R-HSA-8953854 |
Metabolism of RNA |
| Reactome:R-HSA-72163 |
pre-mRNA splicing |
| Reactome:R-MMU-69620 |
Cell Cycle Checkpoints |
| Reactome:R-MMU-69541 |
Stabilization of p53 |
| Reactome:R-MMU-69613 |
p53-Independent G1/S DNA Damage Checkpoint |
| Reactome:R-MMU-69275 |
G2/M Transition |
| Reactome:R-MMU-1280218 |
Adaptive Immune System |
| Reactome:R-MMU-168898 |
Toll-like Receptor Cascades |
| Reactome:R-MMU-937041 |
IKK complex recruitment mediated by RIP1 |
| Reactome:R-MMU-1834949 |
Cytosolic sensors of pathogen-associated DNA |
| Reactome:R-MMU-1834941 |
STING mediated induction of host immune responses |
| Reactome:R-MMU-1169410 |
Antiviral mechanism by IFN-stimulated genes |
| Reactome:R-MMU-446652 |
Interleukin-1 family signaling |
| Reactome:R-MMU-5668541 |
TNFR2 non-canonical NF-kB pathway |
| Reactome:R-MMU-73894 |
DNA Repair |
| Reactome:R-MMU-110314 |
Recognition of DNA damage by PCNA-containing replication complex |
| Reactome:R-MMU-5693565 |
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
| Reactome:R-MMU-5693571 |
Nonhomologous End-Joining (NHEJ) |
| Reactome:R-MMU-5696395 |
Formation of Incision Complex in GG-NER |
| Reactome:R-MMU-6781823 |
Formation of TC-NER Pre-Incision Complex |
| Reactome:R-MMU-196791 |
Vitamin D (calciferol) metabolism |
| Reactome:R-MMU-1428517 |
Aerobic respiration and respiratory electron transport |
| Reactome:R-MMU-429947 |
Deadenylation of mRNA |
| Reactome:R-MMU-109581 |
Apoptosis |
| Reactome:R-MMU-3371378 |
Regulation by c-FLIP |
| Reactome:R-MMU-111464 |
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes |
| Reactome:R-MMU-1500931 |
Cell-Cell communication |
| Reactome:R-MMU-212436 |
Generic Transcription Pathway |
| Reactome:R-MMU-2173793 |
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| Reactome:R-MMU-6806003 |
Regulation of TP53 Expression and Degradation |
| Reactome:R-MMU-8878166 |
Transcriptional regulation by RUNX2 |
| Reactome:R-MMU-8878159 |
Transcriptional regulation by RUNX3 |
| Reactome:R-MMU-9006934 |
Signaling by Receptor Tyrosine Kinases |
| Reactome:R-MMU-5654736 |
Signaling by FGFR1 |
| Reactome:R-MMU-1295596 |
Spry regulation of FGF signaling |
| Reactome:R-MMU-5654741 |
Signaling by FGFR3 |
| Reactome:R-MMU-1433557 |
Signaling by SCF-KIT |
| Reactome:R-MMU-6806834 |
Signaling by MET |
| Reactome:R-MMU-9006936 |
Signaling by TGFB family members |
| Reactome:R-MMU-195721 |
Signaling by WNT |
| Reactome:R-MMU-5610787 |
Hedgehog 'off' state |
| Reactome:R-MMU-5673000 |
RAF activation |
| Reactome:R-MMU-5658442 |
Regulation of RAS by GAPs |
| Reactome:R-MMU-8848021 |
Signaling by PTK6 |
| Reactome:R-MMU-73887 |
Death Receptor Signaling |
| Reactome:R-MMU-5357786 |
TNFR1-induced proapoptotic signaling |
| Reactome:R-MMU-392499 |
Metabolism of proteins |
| Reactome:R-MMU-597592 |
Post-translational protein modification |
| Reactome:R-MMU-2990846 |
SUMOylation |
| Reactome:R-MMU-3108214 |
SUMOylation of DNA damage response and repair proteins |
| Reactome:R-MMU-4090294 |
SUMOylation of intracellular receptors |
| Reactome:R-MMU-4755510 |
SUMOylation of immune response proteins |
| Reactome:R-MMU-5653656 |
Vesicle-mediated transport |
| Reactome:R-MMU-112315 |
Transmission across Chemical Synapses |
| Reactome:R-MMU-112314 |
Neurotransmitter receptors and postsynaptic signal transmission |
| Reactome:R-MMU-399721 |
Glutamate binding, activation of AMPA receptors and synaptic plasticity |
| Reactome:R-RNO-72172 |
mRNA Splicing |
| Reactome:R-RNO-1430728 |
Metabolism |
| Reactome:R-RNO-1428517 |
Aerobic respiration and respiratory electron transport |
| Reactome:R-RNO-3108232 |
SUMO E3 ligases SUMOylate target proteins |
| Reactome:R-RNO-4551638 |
SUMOylation of chromatin organization proteins |
| Reactome:R-RNO-5688426 |
Deubiquitination |
| Reactome:R-RNO-8866654 |
E3 ubiquitin ligases ubiquitinate target proteins |
| Reactome:R-RNO-74160 |
Gene expression (Transcription) |
| Reactome:R-RNO-73857 |
RNA Polymerase II Transcription |
| Reactome:R-RNO-195721 |
Signaling by WNT |
| Reactome:R-RNO-9006925 |
Intracellular signaling by second messengers |
| Reactome:R-RNO-199418 |
Negative regulation of the PI3K/AKT network |
| Reactome:R-RNO-8964043 |
Plasma lipoprotein clearance |
| Reactome:R-RNO-5693532 |
DNA Double-Strand Break Repair |
| Reactome:R-RNO-5693538 |
Homology Directed Repair |
| Reactome:R-RNO-5696398 |
Nucleotide Excision Repair |
| Reactome:R-RNO-6782135 |
Dual incision in TC-NER |
| Reactome:R-RNO-5357801 |
Programmed Cell Death |
| Reactome:R-RNO-111463 |
SMAC (DIABLO) binds to IAPs |
| Reactome:R-RNO-202403 |
TCR signaling |
| Reactome:R-RNO-202424 |
Downstream TCR signaling |
| Reactome:R-RNO-937042 |
IRAK2 mediated activation of TAK1 complex |
| Reactome:R-RNO-450302 |
activated TAK1 mediates p38 MAPK activation |
| Reactome:R-RNO-168164 |
Toll Like Receptor 3 (TLR3) Cascade |
| Reactome:R-RNO-975155 |
MyD88 dependent cascade initiated on endosome |
| Reactome:R-RNO-166058 |
MyD88:MAL(TIRAP) cascade initiated on plasma membrane |
| Reactome:R-RNO-937072 |
TRAF6-mediated induction of TAK1 complex within TLR4 complex |
| Reactome:R-RNO-5607764 |
CLEC7A (Dectin-1) signaling |
| Reactome:R-SCE-6781827 |
Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| Reactome:R-SPO-72203 |
Processing of Capped Intron-Containing Pre-mRNA |
| Reactome:R-SPO-392499 |
Metabolism of proteins |
| Reactome:R-SPO-2990846 |
SUMOylation |
| Reactome:R-SPO-6782135 |
Dual incision in TC-NER |
| Reactome:R-SSC-209560 |
NF-kB is activated and signals survival |
| Reactome:R-SSC-193692 |
Regulated proteolysis of p75NTR |
| Reactome:R-SSC-1280218 |
Adaptive Immune System |
| Reactome:R-SSC-937042 |
IRAK2 mediated activation of TAK1 complex |
| Reactome:R-SSC-450302 |
activated TAK1 mediates p38 MAPK activation |
| Reactome:R-SSC-168164 |
Toll Like Receptor 3 (TLR3) Cascade |
| Reactome:R-SSC-975155 |
MyD88 dependent cascade initiated on endosome |
| Reactome:R-SSC-166058 |
MyD88:MAL(TIRAP) cascade initiated on plasma membrane |
| Reactome:R-SSC-937041 |
IKK complex recruitment mediated by RIP1 |
| Reactome:R-SSC-168179 |
Toll Like Receptor TLR1:TLR2 Cascade |
| Reactome:R-SSC-2454202 |
Fc epsilon receptor (FCERI) signaling |
| Reactome:R-SSC-446652 |
Interleukin-1 family signaling |
| Reactome:R-XTR-74160 |
Gene expression (Transcription) |
| Reactome:R-XTR-73857 |
RNA Polymerase II Transcription |
| Reactome:R-XTR-168256 |
Immune System |
| Reactome:R-XTR-168898 |
Toll-like Receptor Cascades |
| Reactome:R-XTR-450321 |
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| Reactome:R-XTR-168164 |
Toll Like Receptor 3 (TLR3) Cascade |
| Reactome:R-XTR-975155 |
MyD88 dependent cascade initiated on endosome |
| Reactome:R-XTR-166058 |
MyD88:MAL(TIRAP) cascade initiated on plasma membrane |
| Reactome:R-XTR-181438 |
Toll Like Receptor 2 (TLR2) Cascade |
| Reactome:R-XTR-5607764 |
CLEC7A (Dectin-1) signaling |
| Reactome:R-XTR-392499 |
Metabolism of proteins |
| Reactome:R-BTA-202403 |
TCR signaling |
| Reactome:R-BTA-202424 |
Downstream TCR signaling |
| Reactome:R-BTA-168142 |
Toll Like Receptor 10 (TLR10) Cascade |
| Reactome:R-BTA-445989 |
TAK1-dependent IKK and NF-kappa-B activation |
| Reactome:R-BTA-168176 |
Toll Like Receptor 5 (TLR5) Cascade |
| Reactome:R-BTA-975144 |
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation |
| Reactome:R-BTA-166016 |
Toll Like Receptor 4 (TLR4) Cascade |
| Reactome:R-BTA-937061 |
TRIF (TICAM1)-mediated TLR4 signaling |
| Reactome:R-BTA-937072 |
TRAF6-mediated induction of TAK1 complex within TLR4 complex |
| Reactome:R-BTA-168638 |
NOD1/2 Signaling Pathway |
| Reactome:R-BTA-5607764 |
CLEC7A (Dectin-1) signaling |
| Reactome:R-BTA-203754 |
NOSIP mediated eNOS trafficking |
| Reactome:R-BTA-70268 |
Pyruvate metabolism |
| Reactome:R-BTA-5693607 |
Processing of DNA double-strand break ends |
| Reactome:R-BTA-6781827 |
Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| Reactome:R-BTA-201681 |
TCF dependent signaling in response to WNT |
| Reactome:R-BTA-9006925 |
Intracellular signaling by second messengers |
| Reactome:R-BTA-199418 |
Negative regulation of the PI3K/AKT network |
| Reactome:R-CEL-8953854 |
Metabolism of RNA |
| Reactome:R-CEL-72163 |
pre-mRNA splicing |
| Reactome:R-CEL-6781827 |
Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| Reactome:R-CEL-5673001 |
RAF/MAP kinase cascade |
| Reactome:R-CEL-198323 |
AKT phosphorylates targets in the cytosol |
| Reactome:R-CEL-6807070 |
PTEN Regulation |
| Reactome:R-CFA-1500931 |
Cell-Cell communication |
| Reactome:R-CFA-168256 |
Immune System |
| Reactome:R-CFA-168898 |
Toll-like Receptor Cascades |
| Reactome:R-CFA-166166 |
MyD88-independent TLR4 cascade |
| Reactome:R-CFA-69580 |
p53-Dependent G1/S DNA damage checkpoint |
| Reactome:R-CFA-73857 |
RNA Polymerase II Transcription |
| Reactome:R-CFA-6804757 |
Regulation of TP53 Degradation |
| Reactome:R-CFA-8941858 |
Regulation of RUNX3 expression and activity |
| Reactome:R-CFA-8953750 |
Transcriptional Regulation by E2F6 |
| Reactome:R-DRE-8863795 |
Downregulation of ERBB2 signaling |
| Reactome:R-DRE-8948751 |
Regulation of PTEN stability and activity |
| Reactome:R-DRE-5693532 |
DNA Double-Strand Break Repair |
| Reactome:R-DRE-74160 |
Gene expression (Transcription) |
| Reactome:R-DRE-73857 |
RNA Polymerase II Transcription |
| Reactome:R-DRE-5633007 |
Regulation of TP53 Activity |
| Reactome:R-DRE-6804756 |
Regulation of TP53 Activity through Phosphorylation |
| Reactome:R-DRE-2559585 |
Oncogene Induced Senescence |
| Reactome:R-DRE-1640170 |
Cell Cycle |
| Reactome:R-DRE-69563 |
p53-Dependent G1 DNA Damage Response |
| Reactome:R-DRE-421270 |
Cell-cell junction organization |
| Reactome:R-DRE-196791 |
Vitamin D (calciferol) metabolism |
| Reactome:R-DRE-597592 |
Post-translational protein modification |
| Reactome:R-DRE-3108232 |
SUMO E3 ligases SUMOylate target proteins |
| Reactome:R-DRE-3232142 |
SUMOylation of ubiquitinylation proteins |
| Reactome:R-DRE-5688426 |
Deubiquitination |
| Reactome:R-DRE-8866654 |
E3 ubiquitin ligases ubiquitinate target proteins |
| Reactome:R-DRE-168249 |
Innate Immune System |
| Reactome:R-DRE-975871 |
MyD88 cascade initiated on plasma membrane |
| Reactome:R-DRE-450294 |
MAP kinase activation |
| Reactome:R-DRE-168176 |
Toll Like Receptor 5 (TLR5) Cascade |
| Reactome:R-DRE-975144 |
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation |
| Reactome:R-DRE-166016 |
Toll Like Receptor 4 (TLR4) Cascade |
| Reactome:R-DDI-6782210 |
Gap-filling DNA repair synthesis and ligation in TC-NER |
| Reactome:R-DDI-8852135 |
Protein ubiquitination |
| Reactome:R-DME-72766 |
Translation |
| Reactome:R-DME-3108214 |
SUMOylation of DNA damage response and repair proteins |
| Reactome:R-DME-5689880 |
Ub-specific processing proteases |
| Reactome:R-DME-8852135 |
Protein ubiquitination |
| Reactome:R-DME-1980143 |
Signaling by NOTCH1 |
| Reactome:R-DME-5358351 |
Signaling by Hedgehog |
| Reactome:R-DME-1257604 |
PI3K/AKT Signaling |
| Reactome:R-DME-2559580 |
Oxidative Stress Induced Senescence |
| Reactome:R-DME-212436 |
Generic Transcription Pathway |
| Reactome:R-DME-8939243 |
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known |
| Reactome:R-DME-8953750 |
Transcriptional Regulation by E2F6 |
| Reactome:R-GGA-3214847 |
HATs acetylate histones |
| Reactome:R-HSA-382551 |
Transport of small molecules |
| Reactome:R-HSA-174824 |
Lipoprotein metabolism |
| Reactome:R-HSA-5653656 |
Vesicle-mediated transport |
| Reactome:R-HSA-8856825 |
Cargo recognition for clathrin-mediated endocytosis |
| Reactome:R-HSA-446728 |
Cell junction organization |
| Reactome:R-HSA-202733 |
Cell surface interactions at the vascular wall |
| Reactome:R-HSA-1430728 |
Metabolism |
| Reactome:R-HSA-8957322 |
Metabolism of steroids |
| Reactome:R-HSA-109581 |
Apoptosis |
| Reactome:R-HSA-3371378 |
Regulation by c-FLIP |
| Reactome:R-HSA-111458 |
Formation of apoptosome |
| Reactome:R-HSA-111464 |
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes |
| Reactome:R-HSA-5218859 |
Regulated Necrosis |
| Reactome:R-HSA-73894 |
DNA Repair |
| Reactome:R-HSA-5656169 |
Termination of translesion DNA synthesis |
| Reactome:R-HSA-5693607 |
Processing of DNA double-strand break ends |
| Reactome:R-HSA-5693537 |
Resolution of D-Loop Structures |
| Reactome:R-HSA-5696394 |
DNA Damage Recognition in GG-NER |
| Reactome:R-HSA-6781827 |
Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| Reactome:R-HSA-162582 |
Signaling Pathways |
| Reactome:R-HSA-190236 |
Signaling by FGFR |
| Reactome:R-HSA-5654726 |
Negative regulation of FGFR1 signaling |
| Reactome:R-HSA-5654727 |
Negative regulation of FGFR2 signaling |
| Reactome:R-HSA-1433557 |
Signaling by SCF-KIT |
| Reactome:R-HSA-6807004 |
Negative regulation of MET activity |
| Reactome:R-HSA-2173789 |
TGF-beta receptor signaling activates SMADs |
| Reactome:R-HSA-2173796 |
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| Reactome:R-HSA-9604323 |
Negative regulation of NOTCH4 signaling |
| Reactome:R-HSA-4641258 |
Degradation of DVL |
| Reactome:R-HSA-5358351 |
Signaling by Hedgehog |
| Reactome:R-HSA-5610785 |
GLI3 is processed to GLI3R by the proteasome |
| Reactome:R-HSA-5673001 |
RAF/MAP kinase cascade |
| Reactome:R-HSA-198323 |
AKT phosphorylates targets in the cytosol |
| Reactome:R-HSA-6807070 |
PTEN Regulation |
| Reactome:R-HSA-73887 |
Death Receptor Signaling |
| Reactome:R-HSA-5357786 |
TNFR1-induced proapoptotic signaling |
| Reactome:R-HSA-193704 |
p75 NTR receptor-mediated signalling |
| Reactome:R-HSA-205043 |
NRIF signals cell death from the nucleus |
| Reactome:R-HSA-209543 |
p75NTR recruits signalling complexes |
| Reactome:R-HSA-8953897 |
Cellular responses to stimuli |
| Reactome:R-HSA-397014 |
Muscle contraction |
| Reactome:R-HSA-69580 |
p53-Dependent G1/S DNA damage checkpoint |
| Reactome:R-HSA-69601 |
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A |
| Reactome:R-HSA-69242 |
S Phase |
| Reactome:R-HSA-69052 |
Switching of origins to a post-replicative state |
| Reactome:R-HSA-69273 |
Cyclin A/B1/B2 associated events during G2/M transition |
| Reactome:R-HSA-3232118 |
SUMOylation of transcription factors |
| Reactome:R-HSA-4085377 |
SUMOylation of SUMOylation proteins |
| Reactome:R-HSA-5689603 |
UCH proteinases |
| Reactome:R-HSA-1643713 |
Signaling by EGFR in Cancer |
| Reactome:R-HSA-5637810 |
Constitutive Signaling by EGFRvIII |
| Reactome:R-HSA-5655302 |
Signaling by FGFR1 in disease |
| Reactome:R-HSA-1839117 |
Signaling by cytosolic FGFR1 fusion mutants |
| Reactome:R-HSA-2219528 |
PI3K/AKT Signaling in Cancer |
| Reactome:R-HSA-2644603 |
Signaling by NOTCH1 in Cancer |
| Reactome:R-HSA-2894862 |
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants |
| Reactome:R-HSA-5387390 |
Hh mutants abrogate ligand secretion |
| Reactome:R-HSA-5663205 |
Infectious disease |
| Reactome:R-HSA-8876493 |
InlA-mediated entry of Listeria monocytogenes into host cells |
| Reactome:R-HSA-3247509 |
Chromatin modifying enzymes |
| Reactome:R-HSA-6806003 |
Regulation of TP53 Expression and Degradation |
| Reactome:R-HSA-8878166 |
Transcriptional regulation by RUNX2 |
| Reactome:R-HSA-8941858 |
Regulation of RUNX3 expression and activity |
| Reactome:R-HSA-1280218 |
Adaptive Immune System |
| Reactome:R-HSA-168898 |
Toll-like Receptor Cascades |
| Reactome:R-HSA-937039 |
IRAK1 recruits IKK complex |
| Reactome:R-HSA-450321 |
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| Reactome:R-HSA-975155 |
MyD88 dependent cascade initiated on endosome |
| Reactome:R-HSA-975110 |
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| Reactome:R-HSA-166058 |
MyD88:MAL(TIRAP) cascade initiated on plasma membrane |
| Reactome:R-HSA-937041 |
IKK complex recruitment mediated by RIP1 |
| Reactome:R-HSA-168179 |
Toll Like Receptor TLR1:TLR2 Cascade |
| Reactome:R-HSA-1606322 |
ZBP1(DAI) mediated induction of type I IFNs |
| Reactome:R-HSA-3270619 |
IRF3-mediated induction of type I IFN |
| Reactome:R-HSA-3134975 |
Regulation of innate immune responses to cytosolic DNA |
| Reactome:R-HSA-2454202 |
Fc epsilon receptor (FCERI) signaling |
| Reactome:R-HSA-1280215 |
Cytokine Signaling in Immune system |
| Reactome:R-HSA-9020702 |
Interleukin-1 signaling |
| Reactome:R-HSA-512988 |
Interleukin-3, Interleukin-5 and GM-CSF signaling |
| Reactome:R-HSA-1059683 |
Interleukin-6 signaling |
| Reactome:R-HSA-5676594 |
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway |
| Reactome:R-MMU-69615 |
G1/S DNA Damage Checkpoints |
| Reactome:R-MMU-349425 |
Autodegradation of the E3 ubiquitin ligase COP1 |
| Reactome:R-MMU-69278 |
Cell Cycle, Mitotic |
| Reactome:R-MMU-69242 |
S Phase |
| Reactome:R-MMU-69052 |
Switching of origins to a post-replicative state |
| Reactome:R-MMU-69273 |
Cyclin A/B1/B2 associated events during G2/M transition |
| Reactome:R-MMU-69306 |
DNA Replication |
| Reactome:R-MMU-166166 |
MyD88-independent TLR4 cascade |
| Reactome:R-MMU-3270619 |
IRF3-mediated induction of type I IFN |
| Reactome:R-MMU-3134975 |
Regulation of innate immune responses to cytosolic DNA |
| Reactome:R-MMU-6783589 |
Interleukin-6 family signaling |
| Reactome:R-MMU-5676594 |
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway |
| Reactome:R-MMU-110313 |
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template |
| Reactome:R-MMU-5693532 |
DNA Double-Strand Break Repair |
| Reactome:R-MMU-5693538 |
Homology Directed Repair |
| Reactome:R-MMU-5696398 |
Nucleotide Excision Repair |
| Reactome:R-MMU-5696400 |
Dual Incision in GG-NER |
| Reactome:R-MMU-6782135 |
Dual incision in TC-NER |
| Reactome:R-MMU-72203 |
Processing of Capped Intron-Containing Pre-mRNA |
| Reactome:R-MMU-72187 |
mRNA 3'-end processing |
| Reactome:R-MMU-382551 |
Transport of small molecules |
| Reactome:R-MMU-174824 |
Lipoprotein metabolism |
| Reactome:R-MMU-9609507 |
Protein localization |
| Reactome:R-MMU-109582 |
Hemostasis |
| Reactome:R-MMU-210991 |
Basigin interactions |
| Reactome:R-MMU-5357769 |
Caspase activation via extrinsic apoptotic signalling pathway |
| Reactome:R-MMU-111471 |
Apoptotic factor-mediated response |
| Reactome:R-MMU-75153 |
Apoptotic execution phase |
| Reactome:R-MMU-5218859 |
Regulated Necrosis |
| Reactome:R-MMU-8953897 |
Cellular responses to stimuli |
| Reactome:R-MMU-2262752 |
Cellular responses to stress |
| Reactome:R-MMU-1234176 |
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha |
| Reactome:R-MMU-2559583 |
Cellular Senescence |
| Reactome:R-MMU-446728 |
Cell junction organization |
| Reactome:R-MMU-4839726 |
Chromatin organization |
| Reactome:R-MMU-2173796 |
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| Reactome:R-MMU-6804115 |
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain |
| Reactome:R-MMU-6804760 |
Regulation of TP53 Activity through Methylation |
| Reactome:R-MMU-8939902 |
Regulation of RUNX2 expression and activity |
| Reactome:R-MMU-8941858 |
Regulation of RUNX3 expression and activity |
| Reactome:R-MMU-8953750 |
Transcriptional Regulation by E2F6 |
| Reactome:R-MMU-177929 |
Signaling by EGFR |
| Reactome:R-MMU-5654738 |
Signaling by FGFR2 |
| Reactome:R-MMU-5654732 |
Negative regulation of FGFR3 signaling |
| Reactome:R-MMU-1433559 |
Regulation of KIT signaling |
| Reactome:R-MMU-8863795 |
Downregulation of ERBB2 signaling |
| Reactome:R-MMU-170834 |
Signaling by TGF-beta Receptor Complex |
| Reactome:R-MMU-201681 |
TCF dependent signaling in response to WNT |
| Reactome:R-MMU-3769402 |
Deactivation of the beta-catenin transactivating complex |
| Reactome:R-MMU-5358351 |
Signaling by Hedgehog |
| Reactome:R-MMU-5610785 |
GLI3 is processed to GLI3R by the proteasome |
| Reactome:R-MMU-5683057 |
MAPK family signaling cascades |
| Reactome:R-MMU-9006925 |
Intracellular signaling by second messengers |
| Reactome:R-MMU-8849469 |
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 |
| Reactome:R-MMU-72766 |
Translation |
| Reactome:R-MMU-3108232 |
SUMO E3 ligases SUMOylate target proteins |
| Reactome:R-MMU-4551638 |
SUMOylation of chromatin organization proteins |
| Reactome:R-MMU-3232142 |
SUMOylation of ubiquitinylation proteins |
| Reactome:R-MMU-5688426 |
Deubiquitination |
| Reactome:R-MMU-8866654 |
E3 ubiquitin ligases ubiquitinate target proteins |
| Reactome:R-MMU-8951664 |
Neddylation |
| Reactome:R-MMU-199991 |
Membrane Trafficking |
| Reactome:R-MMU-112316 |
Neuronal System |
| Reactome:R-MMU-399719 |
Trafficking of AMPA receptors |
| Reactome:R-RNO-8953854 |
Metabolism of RNA |
| Reactome:R-RNO-72163 |
pre-mRNA splicing |
| Reactome:R-RNO-5689603 |
UCH proteinases |
| Reactome:R-RNO-212436 |
Generic Transcription Pathway |
| Reactome:R-RNO-212165 |
Epigenetic regulation of gene expression |
| Reactome:R-RNO-201681 |
TCF dependent signaling in response to WNT |
| Reactome:R-RNO-3769402 |
Deactivation of the beta-catenin transactivating complex |
| Reactome:R-RNO-1257604 |
PI3K/AKT Signaling |
| Reactome:R-RNO-6811558 |
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling |
| Reactome:R-RNO-8948751 |
Regulation of PTEN stability and activity |
| Reactome:R-RNO-75893 |
TNF signaling |
| Reactome:R-RNO-5357905 |
Regulation of TNFR1 signaling |
| Reactome:R-RNO-204998 |
Cell death signalling via NRAGE, NRIF and NADE |
| Reactome:R-RNO-193639 |
p75NTR signals via NF-kB |
| Reactome:R-RNO-8866427 |
VLDLR internalisation and degradation |
| Reactome:R-RNO-9033241 |
Peroxisomal protein import |
| Reactome:R-RNO-5693606 |
DNA Double Strand Break Response |
| Reactome:R-RNO-5693567 |
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| Reactome:R-RNO-5685938 |
HDR through Single Strand Annealing (SSA) |
| Reactome:R-RNO-6782210 |
Gap-filling DNA repair synthesis and ligation in TC-NER |
| Reactome:R-RNO-109581 |
Apoptosis |
| Reactome:R-RNO-111464 |
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes |
| Reactome:R-RNO-388841 |
Costimulation by the CD28 family |
| Reactome:R-RNO-168142 |
Toll Like Receptor 10 (TLR10) Cascade |
| Reactome:R-RNO-445989 |
TAK1-dependent IKK and NF-kappa-B activation |
| Reactome:R-RNO-975138 |
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation |
| Reactome:R-RNO-168138 |
Toll Like Receptor 9 (TLR9) Cascade |
| Reactome:R-RNO-166166 |
MyD88-independent TLR4 cascade |
| Reactome:R-RNO-181438 |
Toll Like Receptor 2 (TLR2) Cascade |
| Reactome:R-RNO-2871837 |
FCERI mediated NF-kB activation |
| Reactome:R-RNO-1280215 |
Cytokine Signaling in Immune system |
| Reactome:R-RNO-9020702 |
Interleukin-1 signaling |
| Reactome:R-SCE-73894 |
DNA Repair |
| Reactome:R-SCE-9033241 |
Peroxisomal protein import |
| Reactome:R-SCE-392499 |
Metabolism of proteins |
| Reactome:R-SCE-3108214 |
SUMOylation of DNA damage response and repair proteins |
| Reactome:R-SPO-72172 |
mRNA Splicing |
| Reactome:R-SPO-9609507 |
Protein localization |
| Reactome:R-SPO-72766 |
Translation |
| Reactome:R-SPO-597592 |
Post-translational protein modification |
| Reactome:R-SPO-3108232 |
SUMO E3 ligases SUMOylate target proteins |
| Reactome:R-SPO-73894 |
DNA Repair |
| Reactome:R-SPO-5696398 |
Nucleotide Excision Repair |
| Reactome:R-SPO-6782210 |
Gap-filling DNA repair synthesis and ligation in TC-NER |
| Reactome:R-SSC-162582 |
Signaling Pathways |
| Reactome:R-SSC-73887 |
Death Receptor Signaling |
| Reactome:R-SSC-193704 |
p75 NTR receptor-mediated signalling |
| Reactome:R-SSC-202403 |
TCR signaling |
| Reactome:R-SSC-202424 |
Downstream TCR signaling |
| Reactome:R-SSC-168142 |
Toll Like Receptor 10 (TLR10) Cascade |
| Reactome:R-SSC-445989 |
TAK1-dependent IKK and NF-kappa-B activation |
| Reactome:R-SSC-975138 |
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation |
| Reactome:R-SSC-168138 |
Toll Like Receptor 9 (TLR9) Cascade |
| Reactome:R-SSC-166166 |
MyD88-independent TLR4 cascade |
| Reactome:R-SSC-168188 |
Toll Like Receptor TLR6:TLR2 Cascade |
| Reactome:R-SSC-5621481 |
C-type lectin receptors (CLRs) |
| Reactome:R-SSC-597592 |
Post-translational protein modification |
| Reactome:R-SSC-5689896 |
Ovarian tumor domain proteases |
| Reactome:R-XTR-212436 |
Generic Transcription Pathway |
| Reactome:R-XTR-2173793 |
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| Reactome:R-XTR-1280218 |
Adaptive Immune System |
| Reactome:R-XTR-937042 |
IRAK2 mediated activation of TAK1 complex |
| Reactome:R-XTR-450302 |
activated TAK1 mediates p38 MAPK activation |
| Reactome:R-XTR-975138 |
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation |
| Reactome:R-XTR-168138 |
Toll Like Receptor 9 (TLR9) Cascade |
| Reactome:R-XTR-166166 |
MyD88-independent TLR4 cascade |
| Reactome:R-XTR-168179 |
Toll Like Receptor TLR1:TLR2 Cascade |
| Reactome:R-XTR-2871837 |
FCERI mediated NF-kB activation |
| Reactome:R-XTR-162582 |
Signaling Pathways |
| Reactome:R-XTR-8948751 |
Regulation of PTEN stability and activity |
| Reactome:R-XTR-193704 |
p75 NTR receptor-mediated signalling |
| Reactome:R-XTR-193639 |
p75NTR signals via NF-kB |
| WikiPathways:WP5287 |
17q12 copy number variation syndrome |
| WikiPathways:WP5381 |
Smith-Magenis and Potocki-Lupski syndrome copy number variation |
| WikiPathways:WP1971 |
Integrated cancer pathway |
| WikiPathways:WP2516 |
ATM signaling pathway |
| WikiPathways:WP3959 |
DNA IR-double strand breaks and cellular response via ATM |
| WikiPathways:WP4016 |
DNA IR-damage and cellular response via ATR |
| WikiPathways:WP5098 |
T-cell activation SARS-CoV-2 |
| WikiPathways:WP2263 |
Androgen receptor network in prostate cancer |
| WikiPathways:WP5322 |
CKAP4 signaling pathway map |
| WikiPathways:WP5182 |
Pro-survival signaling of neuroprotectin D1 |
| WikiPathways:WP1984 |
Integrated breast cancer pathway |
| PathBank:SMP0031696 |
Dasatinib Inhibition of BCR-ABL |
| PathBank:SMP0031700 |
Ponatinib Inhibition of BCR-ABL |
| PathBank:SMP0120931 |
Toll-Like Receptor Pathway 1 |
| PathBank:SMP0120955 |
Toll-Like Receptor Pathway 1 |
| PathBank:SMP0089759 |
CD40L Signalling Pathway |
| PathBank:SMP0063810 |
EGF Signalling Pathway |
| PathBank:SMP0063899 |
Toll-Like Receptor Pathway 1 |
| PathBank:SMP0066977 |
T Cell Receptor Signaling Pathway |
| PathBank:SMP0031694 |
Imatinib Inhibition of BCR-ABL |
| PathBank:SMP0031699 |
Bafetinib Inhibition of BCR-ABL |
| PathBank:SMP0069695 |
FAS signaling pathway ( CD95 ) |
| PathBank:SMP0120926 |
NF-kB Signaling Pathway |
| PathBank:SMP0120942 |
CD40L Signalling Pathway |
| PathBank:SMP0120946 |
LPS and Citrate Signaling and Inflammation |
| PathBank:SMP0120950 |
NF-kB Signaling Pathway |
| PathBank:SMP0120966 |
CD40L Signalling Pathway |
| PathBank:SMP0120970 |
LPS and Citrate Signaling and Inflammation |
| PathBank:SMP0063795 |
Rac 1 Cell Motility Signaling Pathway |
| PathBank:SMP0100483 |
TNF/Stress Related Signaling |
| PathBank:SMP0100498 |
TNF/Stress Related Signaling |
| PathBank:SMP0031692 |
BCR-ABL Action in CML Pathogenesis |
| PathBank:SMP0031698 |
Bosutinib Inhibition of BCR-ABL |
| PathBank:SMP0069871 |
BCR Signaling Pathway |
| PathBank:SMP0000320 |
Intracellular Signalling Through Adenosine Receptor A2a and Adenosine |
| PathBank:SMP0063792 |
TNF/Stress Related Signaling |
| PathBank:SMP0063813 |
NF-kB Signaling Pathway |
| PathBank:SMP0100046 |
LPS and Citrate Signaling and Inflammation |
| PathBank:SMP0031697 |
Nilotinib Inhibition of BCR-ABL |
| PathBank:SMP0069593 |
Toll-Like Receptor Pathway 2 |
| PathBank:SMP0120937 |
Toll-Like Receptor Pathway 2 |
| PathBank:SMP0120961 |
Toll-Like Receptor Pathway 2 |
| PathBank:SMP0000321 |
Intracellular Signalling Through Adenosine Receptor A2b and Adenosine |
| PathBank:SMP0063811 |
GnRH Signaling Pathway |
| PathBank:SMP0063816 |
Ubiquitin Proteasome Pathway |