EC: 1.1.1.41

isocitrate dehydrogenase (NAD+) (isocitrate:NAD+ oxidoreductase (decarboxylating))

enzyme lambda metabolic reaction experiment
- [Ca2+]

Isocitrate + NAD+ -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (( (Vmax * (M ^ n)) ) / (( (K05 ^ n) ) + (M ^ n))) ) + v0) buffer: 1 mM ADP, 2 µg/ml Rotenone, 1 mM Mg2+, 2 mM EGTA
PH: 7
Temperature: 30
- [Ca2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + H+ + CO2 + NADH		 (( (( (Vmax * (M ^ n)) ) / (( (K05 ^ n) ) + (M ^ n))) ) + v0) buffer: 1 mM ADP, 2 µg/ml Rotenone, 1 mM Mg2+, 2 mM EGTA
PH: 7
Temperature: 30
- [Ca2+]

NAD+ + Isocitrate -> CO2 + 2_Oxoglutarate + NADH + H+		 (( (Vmax * (B ^ n)) ) / (( (Km ^ n) ) + (B ^ n))) buffer: 1 mM ADP, 2 µg/ml Rotenone, 1 mM Mg2+, 2 mM EGTA
PH: 7
Temperature: 30
- [Ca2+]

NAD+ + Isocitrate -> NADH + CO2 + H+ + 2_Oxoglutarate		 (( (Vmax * (B ^ n)) ) / (( (Km ^ n) ) + (B ^ n))) buffer: 1 mM ADP, 2 µg/ml Rotenone, 1 mM Mg2+, 2 mM EGTA
PH: 7
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 50 mM Hepes
PH: 7.6
Temperature: 25
- [Mg2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 50 mM Hepes
PH: 7.6
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + NADH		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [ADP]

NAD+ + D_threo_Isocitrate -> CO2 + NADH + 2_Oxoglutarate		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [ADP]

D_threo_Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + CO2		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [ADP]

D_threo_Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + CO2		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [Mn2+]

Isocitrate + NAD+ -> CO2 + 2_Oxoglutarate + NADH + H+		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> H+ + CO2 + 2_Oxoglutarate + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> NADH + CO2 + H+ + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> 2_Oxoglutarate + H+ + NADH + CO2		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> NADH + CO2 + H+ + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + H+ + CO2		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + H+ + CO2		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

NAD+ + Isocitrate -> CO2 + 2_Oxoglutarate + H+ + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

NAD+ + Isocitrate -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> CO2 + 2_Oxoglutarate + H+ + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> CO2 + 2_Oxoglutarate + H+ + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + CO2 + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

NAD+ + Isocitrate -> NADH + H+ + 2_Oxoglutarate + CO2		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + CO2 + H+		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> H+ + NADH + CO2 + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + H+ + CO2		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> CO2 + 2_Oxoglutarate + H+ + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + D_threo_Isocitrate -> 2_Oxoglutarate + NADH + CO2		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [Citrate]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Citrate]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + NADH + H+		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Citrate]

Isocitrate + NAD+ -> 2_Oxoglutarate + H+ + CO2 + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

NAD+ + Isocitrate -> H+ + 2_Oxoglutarate + CO2 + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + H+ + CO2 + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + NADH + H+		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [ADP]

D_threo_Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + CO2		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [ADP]

D_threo_Isocitrate + NAD+ -> NADH + CO2 + 2_Oxoglutarate		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [ADP]

NAD+ + D_threo_Isocitrate -> CO2 + 2_Oxoglutarate + NADH		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [ADP]

NAD+ + D_threo_Isocitrate -> 2_Oxoglutarate + CO2 + NADH		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [ADP]

NAD+ + D_threo_Isocitrate -> CO2 + 2_Oxoglutarate + NADH		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [Ca2+]

D_threo_Isocitrate + NAD+ -> NADH + CO2 + 2_Oxoglutarate		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [ADP]

D_threo_Isocitrate + NAD+ -> CO2 + NADH + 2_Oxoglutarate		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [EGTA]

D_threo_Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + CO2		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [ADP]

NAD+ + D_threo_Isocitrate -> NADH + CO2 + 2_Oxoglutarate		 (V / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM 4-Morpholinepropanesulphonic acid, 2 µg/ml Rotenone
PH: 7
Temperature: 30
- [Citrate]

NAD+ + Isocitrate -> H+ + CO2 + 2_Oxoglutarate + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Citrate]

NAD+ + Isocitrate -> H+ + NADH + CO2 + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Citrate]

NAD+ + Isocitrate -> H+ + CO2 + 2_Oxoglutarate + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Citrate]

Isocitrate + NAD+ -> H+ + CO2 + 2_Oxoglutarate + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Citrate]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + H+ + CO2		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Citrate]

NAD+ + Isocitrate -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Citrate]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Citrate]

NAD+ + Isocitrate -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> CO2 + H+ + 2_Oxoglutarate + NADH		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P08200 [isocitrate dehydrogenase (NAD+)(Enzyme) mutant K344D, Y345I, V351A, Y391K, R395S, C332Y]

NAD+ + Isocitrate -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Mops, 100 mM NaCl, 5 mM MgCl2, 1 mM DTT
PH: 7.5
Temperature: 21
uniprot:P08200 [isocitrate dehydrogenase (NAD+)(Enzyme) mutant K344D, Y345I, V351A, Y391K, R395S, C332Y, C201I]

NAD+ + Isocitrate -> H+ + CO2 + 2_Oxoglutarate + NADH		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Mops, 100 mM NaCl, 5 mM MgCl2, 1 mM DTT
PH: 7.5
Temperature: 21
uniprot:P08200 [isocitrate dehydrogenase (NAD+)(Enzyme) mutant K344D, Y345I, V351A, Y391G, R395G]

NAD+ + Isocitrate -> NADH + CO2 + 2_Oxoglutarate + H+		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Mops, 100 mM NaCl, 5 mM MgCl2, 1 mM DTT
PH: 7.5
Temperature: 21
uniprot:P08200 [isocitrate dehydrogenase (NAD+)(Enzyme) mutant K344D, Y345I, V351A, Y391K, R395S, Q316L, V317P, G319S, I320L]

NAD+ + Isocitrate -> CO2 + H+ + 2_Oxoglutarate + NADH		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Mops, 100 mM NaCl, 5 mM MgCl2, 1 mM DTT
PH: 7.5
Temperature: 21
uniprot:P50213 [ADP]

NAD+ + Isocitrate -> NADH + H+ + 2_Oxoglutarate + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [ADP]

NAD+ + Isocitrate -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (Vmax * A) ) / (Km + A)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> CO2 + H+ + NADH + 2_Oxoglutarate		 (( (Vmax * B) ) / (Km + B)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * B) ) / (Km + B)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> H+ + NADH + 2_Oxoglutarate + CO2		 (( (Vmax * M) ) / (Km + M)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> CO2 + 2_Oxoglutarate + H+ + NADH		 (( (Vmax * A) ) / (Km + A)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * A) ) / (Km + A)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (Vmax * M) ) / (Km + M)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + NADH + H+		 (( (Vmax * M) ) / (Km + M)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P08200 [isocitrate dehydrogenase (NAD+)(Enzyme) mutant K344D, Y345I, V351A]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + H+ + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Mops, 100 mM NaCl, 5 mM MgCl2, 1 mM DTT
PH: 7.5
Temperature: 21
uniprot:P08200 [isocitrate dehydrogenase (NAD+)(Enzyme) mutant K344D, Y345I, V351A, Y391K, R395S, R292D]

Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + CO2 + H+		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Mops, 100 mM NaCl, 5 mM MgCl2, 1 mM DTT
PH: 7.5
Temperature: 21
uniprot:P08200 [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

Isocitrate + NAD+ -> NADH + H+ + 2_Oxoglutarate + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Mops, 100 mM NaCl, 5 mM MgCl2, 1 mM DTT
PH: 7.5
Temperature: 21
uniprot:P08200 [isocitrate dehydrogenase (NAD+)(Enzyme) mutant K344D, Y345I]

NAD+ + Isocitrate -> NADH + CO2 + H+ + 2_Oxoglutarate		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Mops, 100 mM NaCl, 5 mM MgCl2, 1 mM DTT
PH: 7.5
Temperature: 21
uniprot:P08200 [isocitrate dehydrogenase (NAD+)(Enzyme) mutant K344D, Y345I, V351A, Y391K, R395S]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Mops, 100 mM NaCl, 5 mM MgCl2, 1 mM DTT
PH: 7.5
Temperature: 21
uniprot:Q8G490 [Mg2+]

Isocitrate + NAD+ -> H+ + NADH + CO2 + 2_Oxoglutarate		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 35 mM Tris-HCl
PH: 8
Temperature: 25
uniprot:P50213 [ADP]

Isocitrate + NAD+ -> H+ + NADH + 2_Oxoglutarate + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * B) ) / (Km + B)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * A) ) / (Km + A)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (Vmax * M) ) / (Km + M)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [ADP]

Isocitrate + NAD+ -> NADH + H+ + 2_Oxoglutarate + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 30 mM MES
PH: 6.1
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * B) ) / (Km + B)) buffer: 30 mM MES
PH: 6.1
Temperature: 25
uniprot:P50213 [ADP]

Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + H+ + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 30 mM MES
PH: 6.1
Temperature: 25
uniprot:P50213 [ADP]

Isocitrate + NAD+ -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * A) ) / (Km + A)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + H+ + CO2 + NADH		 (( (Vmax * A) ) / (Km + A)) buffer: 30 mM MES
PH: 6.1
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * B) ) / (Km + B)) buffer: 30 mM MES
PH: 6.1
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * M) ) / (Km + M)) buffer: 30 mM MES
PH: 6.1
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> CO2 + H+ + NADH + 2_Oxoglutarate		 (( (Vmax * A) ) / (Km + A)) buffer: 30 mM MES
PH: 6.1
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * M) ) / (Km + M)) buffer: 30 mM MES
PH: 6.1
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + H+ + CO2		 (( (Vmax * B) ) / (Km + B)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + H+ + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

NAD+ + Isocitrate -> CO2 + 2_Oxoglutarate + NADH + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 25 mM KH2PO4-KOH, 10 mM MgCl2
PH: 7.5
Temperature: 30
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + H+ + CO2		 (( (Vmax * S) ) / (Km + S)) buffer: 25 mM KH2PO4-KOH, 10 mM MgCl2
PH: 7.5
Temperature: 30
- [ADP]

Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + CO2 + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [Mg2+]

NAD+ + Isocitrate -> H+ + NADH + 2_Oxoglutarate + CO2		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.2
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> NADH + CO2 + 2_Oxoglutarate + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> NADH + CO2 + H+ + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> CO2 + H+ + NADH + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [dADP]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [D-ara-ADP]

NAD+ + Isocitrate -> CO2 + H+ + NADH + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [2'-O-methyl-ADP]

NAD+ + Isocitrate -> 2_Oxoglutarate + H+ + CO2 + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [3'-deoxy-ADP]

NAD+ + Isocitrate -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> H+ + 2_Oxoglutarate + CO2 + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + NADH + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> H+ + NADH + CO2 + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [7-Deazaadenosine 5'-diphosphate]

Isocitrate + NAD+ -> H+ + CO2 + 2_Oxoglutarate + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [2-NH2-ADP]

NAD+ + Isocitrate -> NADH + CO2 + H+ + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [2-NH2-ADP]

NAD+ + Isocitrate -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [2',3'-dideoxy-ADP]

NAD+ + Isocitrate -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
uniprot:complex [Adenylyl imidodiphosphate]

NAD+ + Isocitrate -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + CO2 + NADH		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> H+ + 2_Oxoglutarate + CO2 + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

Isocitrate + NAD+ -> CO2 + H+ + 2_Oxoglutarate + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + NADH + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP-alpha-S]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP-beta-S]

Isocitrate + NAD+ -> H+ + NADH + CO2 + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP-amide]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 167 mM Na-Hepes
PH: 7.4
Temperature: 25
- [ADP]

NAD+ + D_threo_Isocitrate -> 2_Oxoglutarate + CO2 + NADH		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 33.3 mM potassium cacodylate
PH: 6.5
Temperature: 25
- [ADP]

D_threo_Isocitrate + NAD+ -> NADH + CO2 + 2_Oxoglutarate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 33.3 mM Tris-acetate
PH: 7.2
Temperature: 25
- [Mn2+]

NAD+ + D_threo_Isocitrate -> 2_Oxoglutarate + CO2 + NADH		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 33.3 mM Tris-acetate
PH: 7.2
Temperature: 25
- [Mn2+]

D_threo_Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + CO2		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 33.3 mM potassium cacodylate
PH: 6.5
Temperature: 25
- [Mn2+]

NAD+ + D_threo_Isocitrate -> NADH + CO2 + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 33.3 mM Tris-acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + H+ + CO2		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> NADH + 2_Oxoglutarate + H+ + CO2		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Cd2+]

Isocitrate + NAD+ -> NADH + CO2 + 2_Oxoglutarate + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
- [Ca2+]

NAD+ + Isocitrate -> CO2 + NADH + H+ + 2_Oxoglutarate		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [Ca2+]

NAD+ + Isocitrate -> NADH + H+ + 2_Oxoglutarate + CO2		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [Ca2+]

NAD+ + Isocitrate -> NADH + 2_Oxoglutarate + CO2 + H+		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + NADH + CO2		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

NAD+ + Isocitrate -> NADH + H+ + CO2 + 2_Oxoglutarate		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

Isocitrate + NAD+ -> CO2 + 2_Oxoglutarate + H+ + NADH		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 10 mM MOPS, 120 mM KCl, 1 mM DTT, 1 µM rotenone, 5 mM EGTA
PH: 7
Temperature: 22
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 10 mM MOPS, 120 mM KCl, 1 mM DTT, 1 µM rotenone, 5 mM EGTA
PH: 7
Temperature: 22
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> CO2 + 2_Oxoglutarate + H+ + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> NADH + CO2 + H+ + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + H+ + CO2 + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
- [Mg2+]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> NADH + CO2 + 2_Oxoglutarate + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M imidazole/HCl
PH: 6.5
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 8.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M glycine/NaOH
PH: 9.5
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + NADH + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 8.6
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> H+ + NADH + CO2 + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M glycine/NaOH
PH: 9.5
Temperature: 30
- [Mn2+]

NAD+ + Isocitrate -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tes-NaOH
PH: 7.4
Temperature: 25
- [Mg2+]

Isocitrate + NAD+ -> CO2 + 2_Oxoglutarate + H+ + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tes-NaOH
PH: 7.4
Temperature: 25
- [Mn2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tes-NaOH
PH: 7.4
Temperature: 25
- [Mg2+]

Isocitrate + NAD+ -> CO2 + H+ + NADH + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tes-NaOH
PH: 7.4
Temperature: 25
- [Ca2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 10 mM MOPS, 120 mM KCl, 1 mM DTT, 1 µM rotenone, 5 mM EGTA
PH: 7
Temperature: 22
uniprot:complex [AMP]

Isocitrate + NAD+ -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [AMP]

Isocitrate + NAD+ -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [AMP]

NAD+ + Isocitrate -> CO2 + 2_Oxoglutarate + H+ + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Citrate]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + NADH + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> H+ + 2_Oxoglutarate + CO2 + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [ADP]

Isocitrate + NAD+ -> CO2 + H+ + 2_Oxoglutarate + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.2
Temperature: 25
- [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.2
Temperature: 25
- [Ca2+]

NAD+ + Isocitrate -> NADH + CO2 + 2_Oxoglutarate + H+		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [Ca2+]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + CO2 + NADH		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [Ca2+]

Isocitrate + NAD+ -> CO2 + NADH + H+ + 2_Oxoglutarate		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

NAD+ + Isocitrate -> H+ + CO2 + NADH + 2_Oxoglutarate		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + NADH + CO2		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + H+ + CO2		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [AMP]

NAD+ + Isocitrate -> NADH + CO2 + 2_Oxoglutarate + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Citrate]

Isocitrate + NAD+ -> CO2 + 2_Oxoglutarate + NADH + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> NADH + H+ + 2_Oxoglutarate + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + H+ + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> H+ + NADH + 2_Oxoglutarate + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + CO2 + NADH + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> NADH + H+ + 2_Oxoglutarate + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> CO2 + H+ + NADH + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + NADH + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> NADH + H+ + 2_Oxoglutarate + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> H+ + CO2 + 2_Oxoglutarate + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> CO2 + H+ + 2_Oxoglutarate + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> H+ + NADH + 2_Oxoglutarate + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> NADH + CO2 + 2_Oxoglutarate + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mg2+]

Isocitrate + NAD+ -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> NADH + CO2 + H+ + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + H+ + CO2		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Cd2+]

NAD+ + Isocitrate -> NADH + CO2 + 2_Oxoglutarate + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Cd2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + NADH + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Cd2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + H+ + CO2 + NADH		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
- [isocitrate dehydrogenase (NAD+)(Enzyme) wildtype]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + CO2 + H+		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> CO2 + H+ + 2_Oxoglutarate + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M imidazole/HCl
PH: 6.5
Temperature: 30
- [Mg2+]

NAD+ + Isocitrate -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 0.2 M Tris/acetate
PH: 7.6
Temperature: 30
- [Mn2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + H+ + NADH + CO2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tes-NaOH
PH: 7.4
Temperature: 25
- [Mg2+]

NAD+ + Isocitrate -> NADH + 2_Oxoglutarate + CO2 + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tes-NaOH
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> NADH + CO2 + 2_Oxoglutarate + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> NADH + CO2 + H+ + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
uniprot:P50213 [Cd2+]

NAD+ + Isocitrate -> CO2 + NADH + H+ + 2_Oxoglutarate		 (( (Vmax * S) ) / (Km + S)) buffer: 33 mM Tris acetate
PH: 7.2
Temperature: 25
- [Ca2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + H+ + CO2		 (Vmax / (1 + (( (Km / S) ) ^ n))) buffer: 50 mM Mops, 2 µg/ml rotenone, 1 mM DTT, 1 mM MgCl2, 5 mM EGTA, 1 mM ADP
PH: 7
Temperature: 30
uniprot:P50213 [ADP]

Isocitrate + NAD+ -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ADP]

NAD+ + Isocitrate -> H+ + NADH + CO2 + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [AMP-PNP]

Isocitrate + NAD+ -> CO2 + H+ + 2_Oxoglutarate + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [AMP-PNP]

NAD+ + Isocitrate -> CO2 + H+ + NADH + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> NADH + 2_Oxoglutarate + CO2 + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> CO2 + 2_Oxoglutarate + H+ + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> H+ + 2_Oxoglutarate + CO2 + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + CO2 + H+ + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> 2_Oxoglutarate + H+ + NADH + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> CO2 + H+ + 2_Oxoglutarate + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

NAD+ + Isocitrate -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ADP]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ADP]

NAD+ + Isocitrate -> H+ + NADH + CO2 + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Citrate]

NAD+ + Isocitrate -> CO2 + 2_Oxoglutarate + H+ + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Citrate]

NAD+ + Isocitrate -> CO2 + H+ + NADH + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ADP]

NAD+ + Isocitrate -> 2_Oxoglutarate + NADH + CO2 + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ADP]

NAD+ + Isocitrate -> NADH + 2_Oxoglutarate + CO2 + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> CO2 + NADH + 2_Oxoglutarate + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ATP]

Isocitrate + NAD+ -> H+ + 2_Oxoglutarate + CO2 + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ADP]

NAD+ + Isocitrate -> 2_Oxoglutarate + H+ + CO2 + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ATP]

Isocitrate + NAD+ -> NADH + H+ + CO2 + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ADP]

NAD+ + Isocitrate -> H+ + 2_Oxoglutarate + NADH + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Citrate]

Isocitrate + NAD+ -> H+ + CO2 + 2_Oxoglutarate + NADH		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ATP]

NAD+ + Isocitrate -> H+ + NADH + CO2 + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ATP]

NAD+ + Isocitrate -> CO2 + 2_Oxoglutarate + NADH + H+		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [ADP]

NAD+ + Isocitrate -> NADH + 2_Oxoglutarate + H+ + CO2		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25
uniprot:P50213 [Mn2+]

Isocitrate + NAD+ -> H+ + CO2 + NADH + 2_Oxoglutarate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 33 mM Tris-acetate
PH: 7.4
Temperature: 25

Pathways

pathway id name
BioCyc:META_PWY-5690 TCA cycle II (plants and fungi)
BioCyc:META_PWY-6549 L-glutamine biosynthesis III
BioCyc:META_PWY-5464 superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle
BioCyc:MOUSE_PWY-5690-1 TCA cycle variation III (eukaryotic)
BioCyc:HUMAN_PWY66-407 superpathway of conversion of glucose to acetyl CoA and entry into the TCA cycle
BioCyc:HUMAN_PWY66-398 TCA cycle
BioCyc:META_PWY66-398 TCA cycle III (animals)
BioCyc:YEAST_PWY-5690 TCA cycle II (plants and fungi)
Reactome:R-DME-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-DME-71403 Citric acid cycle (TCA cycle)
Reactome:R-MMU-1430728 Metabolism
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-SPO-71403 Citric acid cycle (TCA cycle)
Reactome:R-DME-1430728 Metabolism
Reactome:R-SCE-1430728 Metabolism
Reactome:R-CEL-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-CEL-71403 Citric acid cycle (TCA cycle)
Reactome:R-HSA-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-HSA-71403 Citric acid cycle (TCA cycle)
Reactome:R-MMU-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-MMU-71403 Citric acid cycle (TCA cycle)
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-RNO-71403 Citric acid cycle (TCA cycle)
Reactome:R-SCE-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-SCE-71403 Citric acid cycle (TCA cycle)
Reactome:R-CEL-1430728 Metabolism
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DDI-1428517 Aerobic respiration and respiratory electron transport
Reactome:R-DDI-71403 Citric acid cycle (TCA cycle)
Reactome:R-HSA-1430728 Metabolism
WikiPathways:WP2624 TCA cycle (Krebs cycle)
PathBank:SMP0120830 Fumarase Deficiency
PathBank:SMP0120834 Pyruvate Dehydrogenase Deficiency (E2)
PathBank:SMP0120613 2-Ketoglutarate Dehydrogenase Complex Deficiency
PathBank:SMP0121182 Citrate Cycle
PathBank:SMP0000548 Mitochondrial Complex II Deficiency
PathBank:SMP0002295 The Oncogenic Action of Fumarate
PathBank:SMP0002358 The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria
PathBank:SMP0087270 Warburg Effect
PathBank:SMP0087274 Citric Acid Cycle
PathBank:SMP0120829 Congenital Lactic Acidosis
PathBank:SMP0120833 Pyruvate Dehydrogenase Deficiency (E3)
PathBank:SMP0108760 Glutaminolysis and Cancer
PathBank:SMP0108771 The Oncogenic Action of 2-Hydroxyglutarate
PathBank:SMP0120612 Mitochondrial Complex II Deficiency
PathBank:SMP0000547 Fumarase Deficiency
PathBank:SMP0000551 Pyruvate Dehydrogenase Deficiency (E2)
PathBank:SMP0002292 The Oncogenic Action of Succinate
PathBank:SMP0120832 2-Ketoglutarate Dehydrogenase Complex Deficiency
PathBank:SMP0108758 The Oncogenic Action of 2-Hydroxyglutarate
PathBank:SMP0108773 Glutaminolysis and Cancer
PathBank:SMP0120610 Congenital Lactic Acidosis
PathBank:SMP0120614 Pyruvate Dehydrogenase Deficiency (E3)
PathBank:SMP0000057 Citric Acid Cycle
PathBank:SMP0000549 2-Ketoglutarate Dehydrogenase Complex Deficiency
PathBank:SMP0000654 Warburg Effect
PathBank:SMP0002359 The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria
PathBank:SMP0002414 TCA Cycle
PathBank:SMP0002426 Glutamine Metabolism
PathBank:SMP0087163 Citric Acid Cycle
PathBank:SMP0087424 Citric Acid Cycle
PathBank:SMP0120831 Mitochondrial Complex II Deficiency
PathBank:SMP0120611 Fumarase Deficiency
PathBank:SMP0120615 Pyruvate Dehydrogenase Deficiency (E2)
PathBank:SMP0000546 Congenital Lactic Acidosis
PathBank:SMP0000550 Pyruvate Dehydrogenase Deficiency (E3)
PathBank:SMP0002291 The Oncogenic Action of 2-Hydroxyglutarate
PathBank:SMP0002298 Glutaminolysis and Cancer
PathBank:SMP0086930 Warburg Effect
PathBank:SMP0087363 Warburg Effect
PathBank:SMP0087527 Warburg Effect
PathBank:SMP0063477 Citric Acid Cycle