EC: 2.7.6.2

thiamine diphosphokinase (ATP:thiamine diphosphotransferase)

enzyme lambda metabolic reaction experiment
uniprot:P41888 [Mg2+]

ATP + Thiamin -> AMP + Thiamine_diphosphate		 (( (Vmax * B) ) / (Km + B)) buffer: 20 mM Tris-HCl
PH: 8.6
Temperature: 37
uniprot:F4IV16 [Mg2+]

ATP + Thiamin -> AMP + Thiamine_diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.02 M Tris-HCl
PH: 7.5
Temperature: 37
uniprot:B9DGU7 [Mg2+]

ATP + Thiamin -> AMP + Thiamine_diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.02 M Tris-HCl
PH: 7.5
Temperature: 37
uniprot:P41888 [Mg2+]

Thiamin + ATP -> AMP + Thiamine_diphosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 20 mM Tris-HCl
PH: 8.6
Temperature: 37
uniprot:P41888 [Mg2+]

ATP + Thiamin -> Thiamine_diphosphate + AMP		 (( (Vmax * Ac) ) / (Km + Ac)) buffer: 20 mM Tris-HCl
PH: 8.6
Temperature: 37

Pathways

pathway id name
BioCyc:META_PWY-6898 thiamine salvage III
BioCyc:YEAST_PWY-7356 thiamin salvage IV
BioCyc:META_PWY-7356 thiamine salvage IV (yeast)
BioCyc:META_PWY-6908 thiamine diphosphate biosynthesis IV (eukaryotes)
BioCyc:YEAST_PWY-6908 thiamin diphosphate biosynthesis IV (eukaryotes)
BioCyc:META_THISYNARA-PWY superpathway of thiamine diphosphate biosynthesis III (eukaryotes)
BioCyc:YEAST_THISYNARA-PWY-1 superpathway of thiamin diphosphate biosynthesis III (eukaryotes)
BioCyc:YEAST_PWY-6898 thiamin salvage III
BioCyc:BSUB_PWY-6898 thiamine salvage III
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-196819 Vitamin B1 (thiamin) metabolism
Reactome:R-CEL-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-CEL-196819 Vitamin B1 (thiamin) metabolism
Reactome:R-SCE-196819 Vitamin B1 (thiamin) metabolism
Reactome:R-SPO-196854 Metabolism of vitamins and cofactors
Reactome:R-CEL-1430728 Metabolism
Reactome:R-CEL-196854 Metabolism of vitamins and cofactors
Reactome:R-SCE-196854 Metabolism of vitamins and cofactors
Reactome:R-SPO-196849 Metabolism of water-soluble vitamins and cofactors
PathBank:SMP0002385 Vitamin B1/Thiamine Metabolism