Humulene
alpha-Humulene, also known as alpha-caryophyllene, belongs to the class of organic compounds known as sesquiterpenoids. These are terpenes with three consecutive isoprene units. Thus, alpha-humulene is considered to be an isoprenoid lipid molecule. alpha-Humulene is found in allspice. alpha-Humulene is a constituent of many essential oils including hops (Humulus lupulus) and cloves (Syzygium aromaticum).
| ID | EC Number | Name |
|---|---|---|
| KEGG:R08373 | 4.2.3.104 | (2E,6E)-farnesyl-diphosphate diphosphate-lyase (alpha-humulene-forming) |
| KEGG:R09934 | 1.14.14.113 | alpha-humulene,[reduced NADPH---hemoprotein reductase]:oxygen 10-oxidoreductase |
| Rhea:RHEA:31896 | 4.2.3.104 | (2E,6E)-farnesyl diphosphate => α-humulene + diphosphate |
| Rhea:RHEA:31897 | 4.2.3.104 | α-humulene + diphosphate => (2E,6E)-farnesyl diphosphate |
| Rhea:RHEA:31898 | 4.2.3.104 | (2E,6E)-farnesyl diphosphate <=> α-humulene + diphosphate |
| Rhea:RHEA:32492 | 1.14.14.113 | α-humulene + reduced [NADPH—hemoprotein reductase] + O2 => 10-hydroxy-α-humulene + oxidized [NADPH—hemoprotein reductase] + H2O + H+ |
| Rhea:RHEA:32493 | 1.14.14.113 | 10-hydroxy-α-humulene + oxidized [NADPH—hemoprotein reductase] + H2O + H+ => α-humulene + reduced [NADPH—hemoprotein reductase] + O2 |
| Rhea:RHEA:32494 | 1.14.14.113 | α-humulene + reduced [NADPH—hemoprotein reductase] + O2 <=> 10-hydroxy-α-humulene + oxidized [NADPH—hemoprotein reductase] + H2O + H+ |
| Rhea:RHEA:68781 | (2Z,6Z)-farnesyl diphosphate => α-humulene + diphosphate | |
| Rhea:RHEA:68782 | α-humulene + diphosphate => (2Z,6Z)-farnesyl diphosphate | |
| Rhea:RHEA:68783 | (2Z,6Z)-farnesyl diphosphate <=> α-humulene + diphosphate | |
| BioCyc:RXN-10628 | 1.14.14.113 | CPD-8233 + Red-NADPH-Hemoprotein-Reductases + OXYGEN-MOLECULE --> CPD-11422 + Ox-NADPH-Hemoprotein-Reductases + WATER |
| BioCyc:RXN-8415 | 4.2.3.104 | FARNESYL-PP --> CPD-8233 + PPI |