D-Arginine

D-Arginine, also known as D-2-amino-5-guanidinovaleric acid or (2R)-2-amino-5-guanidinopentanoate, is a member of the class of compounds known as D-alpha-amino acids. D-alpha-Amino acids are alpha amino acids which have the D-configuration of the alpha-carbon atom. D-Arginine is slightly soluble (in water). D-Arginine can be found in human epidermis and platelet tissues. Within the cell, D-arginine is primarily located in the peroxisome. In humans, D-arginine is involved in D-arginine and D-ornithine metabolism. Arginine (abbreviated as Arg or R) is an alpha-amino acid that is used in the biosynthesis of proteins. It is encoded by the codons CGU, CGC, CGA, CGG, AGA, and AGG. It contains an alpha-amino group, an alpha-carboxylic acid group, and a side chain consisting of a 3-carbon aliphatic straight chain ending in a guanidino group. At physiological pH, the carboxylic acid is deprotonated, the amino group is protonated, and the guanidino group is also protonated to give the guanidinium form (-C-(NH2)2+), making arginine a charged, aliphatic amino acid. It is the precursor for the biosynthesis of nitric oxide. D-Arginine is an essential amino acid that is physiologically active in the L-form.

ID EC Number Name
KEGG:R00567 5.1.1.9 arginine racemase
KEGG:R02458 3.5.3.10 D-arginine amidinohydrolase
KEGG:R02923 1.4.3.3 D-arginine:oxygen oxidoreductase (deaminating)
KEGG:R02924 2.6.1.21 D-arginine:2-oxoglutarate aminotransferase
KEGG:R11016 1.4.99.6 C00792 + C00028<=>C21026 + C00030
KEGG:R11018 1.4.99.6 D-arginine:acceptor oxidoreductase (deaminating)
BioCyc:RXN-15849 CPD-220 + Acceptor --> CPD-17095 + Donor-H2
BioCyc:RXN-7563 1.4.99.6 CPD-220 + WATER + Acceptor --> CPD-824 + AMMONIUM + Donor-H2
BioCyc:ARGININE-RACEMASE-RXN 5.1.1.9 ARG<=>CPD-220
BioCyc:D-ARGINASE-RXN 3.5.3.10 WATER + CPD-220<=>UREA + CPD-217