Androstanediol
The unspecified form of the steroid, normally a major metabolite of testosterone with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.3a,17a-Dihydroxy-5b-androstane is a metabolite of natural androgens (testosterone, epitestosterone, dihydrotestosterone, and dehydroepiandrosterone) present in small amount in the urine of normal individuals (PMID 9381514).
| ID | EC Number | Name |
|---|---|---|
| Rhea:RHEA:42005 | 1.1.1.53 | 5α-androstane-3α,17β-diol + NAD+ => 17β-hydroxy-5α-androstan-3-one + NADH + H+ |
| Rhea:RHEA:42006 | 1.1.1.53 | 17β-hydroxy-5α-androstan-3-one + NADH + H+ => 5α-androstane-3α,17β-diol + NAD+ |
| Rhea:RHEA:42007 | 1.1.1.53 | 5α-androstane-3α,17β-diol + NAD+ <=> 17β-hydroxy-5α-androstan-3-one + NADH + H+ |
| Rhea:RHEA:42117 | 5α-androstane-3α,17β-diol + NADP+ => 17β-hydroxy-5α-androstan-3-one + NADPH + H+ | |
| Rhea:RHEA:42118 | 17β-hydroxy-5α-androstan-3-one + NADPH + H+ => 5α-androstane-3α,17β-diol + NADP+ | |
| Rhea:RHEA:42119 | 5α-androstane-3α,17β-diol + NADP+ <=> 17β-hydroxy-5α-androstan-3-one + NADPH + H+ | |
| Rhea:RHEA:42125 | 5α-androstane-3α,17β-diol + NAD+ => androsterone + NADH + H+ | |
| Rhea:RHEA:42126 | androsterone + NADH + H+ => 5α-androstane-3α,17β-diol + NAD+ | |
| Rhea:RHEA:42127 | 5α-androstane-3α,17β-diol + NAD+ <=> androsterone + NADH + H+ | |
| Rhea:RHEA:42157 | androsterone + NADPH + H+ => 5α-androstane-3α,17β-diol + NADP+ | |
| Rhea:RHEA:42158 | 5α-androstane-3α,17β-diol + NADP+ => androsterone + NADPH + H+ | |
| Rhea:RHEA:42159 | androsterone + NADPH + H+ <=> 5α-androstane-3α,17β-diol + NADP+ |