alpha-Tocotrienol
alpha-Tocotrienol (CAS: 1721-51-3), also known as 5,7,8-trimethyltocotrienol, belongs to the class of organic compounds known as tocotrienols. These are vitamin E derivatives containing an unsaturated trimethyltrideca-3,7,11-trien-1-yl chain attached to the carbon C6 atom of a benzopyran ring system. They differ from tocopherols that contain a saturated trimethyltridecyl chain. Thus, alpha-tocotrienol is considered to be a quinone lipid molecule. alpha-Tocotrienol is found in the blood plasma and all lipoprotein subfractions. Compared to tocopherols, alpha-tocotrienols are poorly studied. Its presence in the blood plasma at nanomolar concentrations is thought to help to prevent stroke-related neurodegeneration (PMID: 16771695). alpha-Tocotrienol has been found to have vitamin E activity.
| ID | EC Number | Name |
|---|---|---|
| KEGG:R10491 | 2.1.1.95 | S-adenosyl-L-methionine:gamma-tocotrienol 5-O-methyltransferase |
| Rhea:RHEA:38096 | 2.1.1.95 | γ-tocotrienol + S-adenosyl-L-methionine => α-tocotrienol + S-adenosyl-L-homocysteine + H+ |
| Rhea:RHEA:38097 | 2.1.1.95 | α-tocotrienol + S-adenosyl-L-homocysteine + H+ => γ-tocotrienol + S-adenosyl-L-methionine |
| Rhea:RHEA:38098 | 2.1.1.95 | γ-tocotrienol + S-adenosyl-L-methionine <=> α-tocotrienol + S-adenosyl-L-homocysteine + H+ |
| BioCyc:RXN-14918 | 2.1.1.95 | S-ADENOSYLMETHIONINE + CPD-15838 --> ADENOSYL-HOMO-CYS + CPD-15836 + PROTON |