BioCyc:3.4.21.38-RXN

This enzyme catalyzes the selective cleavage of Arg | Ile bonds in |FRAME: Factor-VII "factor VII"| to form |FRAME: Factor-VIIa "factor VIIa"| and and |FRAME: Factor-XI "factor XI"| to form |FRAME: Factor-XIa "factor XIa"|.Also activates plasminogen and plasma prokallikrein. Formed from the proenzyme, |FRAME: Factor-XII "factor XII"|, by plasma kallikrein or |FRAME: Factor-XIIa "factor XIIa"| itself. In peptidase family S1 (trypsin family).

WATER + Factor-VII --> Factor-VIIa

H2O[H2O] + [] = []

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Alias

Metabolites

Substrates
metabolite compartment Structure
H2O

Formula: H2O 		Cytoplasm


Formula: 		Cytoplasm
Products
metabolite compartment Structure


Formula: 		Cytoplasm