BioCyc:RXN-8585

This enzyme, characterized from tobacco, is capable of catalysing both cisoid and transoid cyclization pathways |CITS: [20175559]|. When acting on (2E,6E)-farnesyl diphosphate, the enzyme produces |FRAME: ARISTOLOCHENE| as the major product, via the transoid pathway (|FRAME: ARISTOLOCHENE-SYNTHASE-RXN "EC 4.2.3.9, aristolochene synthase"|). When acting on (2Z,6E)-farnesyl-diphosphate, the enzyme produces several products via the cisoid pathway, the major ones being |FRAME: CPD-13069| (44%) (cf. |FRAME: RXN-12117 "EC 4.2.3.m"|), |FRAME: CPD-8776| (21.5%) and |FRAME: CPD-11392| (15.5%) (cf. |FRAME: RXN-10598 "EC 4.2.3.ap"|) |CITS: [20201526]|.

(-)-α-cedrene synthase

(2E,6E)-farnesyl diphosphate[C15H25O7P2] = alpha-Cedrene[C15H24] + diphosphate(3-)[HO7P2]

DB Links

  • BioCyc: RXN-8585
  • EC Number: 4.2.3.-
Alias

Metabolites

Substrates
metabolite compartment Structure
(2E,6E)-farnesyl diphosphate

Formula: C15H25O7P2
Cytoplasm
Products
metabolite compartment Structure
alpha-Cedrene

Formula: C15H24
Cytoplasm
diphosphate(3-)

Formula: HO7P2
Cytoplasm