BioCyc:RXN-14736

This reaction is represented as a composite reaction that is composed of the three sub-reactions shown below it. As indicated in the sub-reactions, the monooxygenase reaction mechanism was proposed to proceed via 26-hydroxylation of |FRAME: CPD-276| to form |FRAME: CPD-15601|, oxidation of the latter compound to a putative aldehyde intermediate |FRAME: CPD-15603|, and further oxidation of the aldehyde to |FRAME: CPD-15602| (20-hydroxyecdysonic acid) |CITS: [20932968][8037696]|. The reaction equations are drawn by analogy with |FRAME: RXN-13713 "EC 1.14.13.15"|.

ecdysone 26-hydroxylase

20-Hydroxyecdysone[C27H44O7] + 3 [] + 3 Oxygen[O2] = 20-hydroxyecdysonate[C27H41O9] + 3 [] + 4 H2O[H2O] + H+[H]

DB Links

Alias

Metabolites

Substrates
metabolite compartment Structure
20-Hydroxyecdysone

Formula: C27H44O7
Cytoplasm


Formula:
Cytoplasm
Oxygen

Formula: O2
Cytoplasm
Products
metabolite compartment Structure
20-hydroxyecdysonate

Formula: C27H41O9
Cytoplasm


Formula:
Cytoplasm
H2O

Formula: H2O
Cytoplasm
H+

Formula: H
Cytoplasm