KEGG:R08664

multi-step reaction (similar to R10671, R00730+R04460+R07190)

L-leucine,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)

L-Leucine[C6H13NO2] + 2 Oxygen[O2] + 2 NADPH[C21H30N7O17P3] + 2 H+[H] = 3-Methylbutyraldehyde oxime[C5H11NO] + 3 H2O[H2O] + 2 NADP+[C21H29N7O17P3] + CO2[CO2]

DB Links

Alias

Metabolites

Substrates
metabolite compartment Structure
L-Leucine

Formula: C6H13NO2
Cytoplasm
Oxygen

Formula: O2
Cytoplasm
NADPH

Formula: C21H30N7O17P3
Cytoplasm
H+

Formula: H
Cytoplasm
Products
metabolite compartment Structure
3-Methylbutyraldehyde oxime

Formula: C5H11NO
Cytoplasm
H2O

Formula: H2O
Cytoplasm
NADP+

Formula: C21H29N7O17P3
Cytoplasm
CO2

Formula: CO2
Cytoplasm