数据之源，洞见之始

3-oxo-dodecanoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> R-3-hydroxydodecanoyl-TYPE-I-FAS-ACPs + NADP

[] + NADP(3-)[C21H25N7O17P3] = [] + NADPH(4-)[C21H26N7O17P3] + H+[H]

DB Links

• BioCyc: RXN66-631
• EC Number: 2.3.1.85
• EC Number: 2.3.1.86

Alias

• [BioCyc:RXN-13387] CPD-14357 + NADPH + PROTON --> CPD-14358 + NADP
• [BioCyc:RXN1G-951] cis,cis-delta19,31-3-oxo-C50:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-21720] 3-oxo-icosanoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> R-3-hydroxyicosanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-21679] 4-Methylpent-2-enoyl-ACP + NADPH + PROTON --> 4-Methylpentanoyl-ACP + NADP
• [BioCyc:RXN-13358] all-trans-3-hydroxyretinol dehydrogenase
• [BioCyc:RXN-9515] crotonyl-[acyl-carrier protein] reductase (NADP)
• [BioCyc:RXN66-625] 2-Octenoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Octanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-21676] 4-Methyl-3-Oxopentanoyl-ACP + NADPH + PROTON --> 4-Methyl-3-Hydroxypentanoyl-ACP + NADP
• [BioCyc:RXN1G-364] cis-delta7-3-oxo-C26:1-[acyl-carrier protein] reductase
• [BioCyc:RXN-21643] 12-Methyltetradec-2-enoyl-ACPs + NADPH + PROTON --> 12-methyltetradecanoyl-ACPs + NADP
• [BioCyc:RXN-21626] 10-Methyl-3-Oxododecanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-10-Methyldodecanoyl-ACPs + NADP
• [BioCyc:RXN1G-1050] cis,cis-delta13,31-3-oxo-C50:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-13008] 3-OXO-EICOSAPENTAENOYL-ACP + NADPH + PROTON --> 3-HYDROXY-DOCOSAPENTAENOYL-ACP + NADP
• [BioCyc:RXN66-638] Tetradec-2-enoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Myristoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-16626] 9Z-3-oxo-octadec-9-enoyl-ACPs + NADPH + PROTON --> 3R-9Z-3-hydroxy-octadec-9-enoyl-ACPs + NADP
• [BioCyc:RXN1G-637] cis,cis-delta11,23-3-oxo-C42:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-21689] 8-Methyl-Non-2-enoyl-ACPs + NADPH + PROTON --> 8-Methylnonanoyl-ACPs + NADP
• [BioCyc:RXN1G-481] cis,cis-delta15,27-3-oxo-C46:2-[acyl-carrier protein] reductase
• [BioCyc:RXN1G-409] cis-cis-D19-37-3-oxo-C56-2-ACPs + NADPH + PROTON --> cis-cis-D19-37-3-hydroxyC56-2-ACPs + NADP
• [BioCyc:RXN1G-358] cis-delta15-3-oxo-C34:1-[acyl-carrier protein] reductase
• [BioCyc:RXN-21640] 6-Methyl-Oct-2-enoyl-ACPs + NADPH + PROTON --> 6-Methyloctanoyl-ACPs + NADP
• [BioCyc:RXN1G-260] cis-delta13-3-oxo-C32:1-[acyl-carrier protein] reductase
• [BioCyc:RXN-9552] 3-oxo-petroslinoyl-[acyl-carrier protein] reductase
• [BioCyc:RXN-9530] trans-Δ²-decenoyl-[acp]reductase
• [BioCyc:RXN66-619] 3-oxo-hexanoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> R-3-hydroxyhexanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-21686] 8-Methyl-3-Oxononanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-8-Methylnonanoyl-ACPs + NADP
• [BioCyc:RXN-21653] 7-Methyl-Oct-2-enoyl-ACPs + NADPH + PROTON --> 7-Methyloctanoyl-ACPs + NADP
• [BioCyc:RXN-9526] trans oct-2-enoyl-[acyl-carrier protein] reductase
• [BioCyc:RXN-21724] 3-oxo-docosanoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> R-3-hydroxydocosanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-21700] 12-Methyltridec-2-enoyl-ACPs + NADPH + PROTON --> 12-methyltridecanoyl-ACPs + NADP
• [BioCyc:RXN-21650] 7-Methyl-3-Oxooctanoyl-ACP + NADPH + PROTON --> 3-Hydroxy-7-Methyloctanoyl-ACPs + NADP
• [BioCyc:RXN1G-240] cis-delta9-3-oxo-C28:1-[acyl-carrier protein] reductase
• [BioCyc:RXN1G-163] cis-delta11-3-oxo-C30:1-[acyl-carrier protein] reductase
• [BioCyc:RXN-9521] trans hex-2-enoyl-[acp] reductase
• [BioCyc:RXN-10060] 3-oxo-cerotoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> R-3-hydroxycerotoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN66-645] 3-Oxo-Acyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> 3R-Hydroxyacyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN66-629] Trans-D2-decenoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Decanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-16616] 5Z-3-oxo-tetradec-5-enoyl-ACPs + NADPH + PROTON --> 3R-5Z-3-hydroxy-tetradec-5-enoyl-ACPs + NADP
• [BioCyc:RXN1G-717] cis,cis-delta17,29-3-oxo-C48:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-21696] 12-Methyl-3-Oxotridecanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-12-Methyltridecanoyl-ACPs + NADP
• [BioCyc:RXN-21663] 11-Methyl-Dodec-2-enoyl-ACPs + NADPH + PROTON --> 11-Methyldodecanoyl-ACPs + NADP
• [BioCyc:RXN-21631] 12-Methyl-3-Oxotetradecanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-12-Methyltetradecanoyl-ACPs + NADP
• [BioCyc:RXN1G-287] cis-delta21-3-oxo-C40:1-[acyl-carrier protein] reductase
• [BioCyc:RXN66-642] 2-Hexadecenoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Palmitoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-16630] 11Z-3-oxo-icos-11-enoyl-ACPs + NADPH + PROTON --> 3R-11Z-3-hydroxy-icos-11-enoyl-ACPs + NADP
• [BioCyc:RXN-21660] 11-Methyl-3-Oxododecanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-11-Methyldodecanoyl-ACPs + NADP
• [BioCyc:RXN-21644] 14-Methyl-Hexadec-2-enoyl-ACPs + NADPH + PROTON --> 14-Methylhexadecanoyl-ACPs + NADP
• [BioCyc:RXN1G-203] cis,cis-delta13,25-3-oxo-C44:2-[acyl-carrier protein] reductase
• [BioCyc:RXN1G-1053] cis-delta19-3-oxo-C38:1-[acyl-carrier protein] reductase
• [BioCyc:RXN-9534] trans dodec-2-enoyl-[acyl-carrier protein] reductase
• [BioCyc:RXN66-623] 3-Oxo-octanoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> 3-Hydroxy-octanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-21673] 15-Methyl-Hexadec-2-enoyl-ACPs + NADPH + PROTON --> 15-Methylhexadecanoyl-ACPs + NADP
• [BioCyc:RXN-21641] 8-Methyl-Dec-2-enoyl-ACPs + NADPH + PROTON --> 8-Methyldecanoyl-ACPs + NADP
• [BioCyc:RXN1G-262] cis,cis-delta7,19-3-oxo-C38:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-18471] 3-oxoacyl-meromycolyl-ACP + NADPH + PROTON --> 3R-hydroxy-meromycolyl-ACP + NADP
• [BioCyc:RXN-20769] 3-oxo-octadecanoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> R-3-hydroxyoctadecanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN66-636] 3-oxo-myristoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> R-3-hydroxymyristoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN1G-853] cis,cis-delta11,29-3-oxo-C48:2-[acyl-carrier protein] reductase
• [BioCyc:RXN1G-613] cis,cis-delta9,27-3-oxo-C46:2-[acyl-carrier protein] reductase
• [BioCyc:RXN1G-469] 3-oxobehenoyl-[acyl-carrier protein] reductase
• [BioCyc:RXN-21670] 15-Methyl-3-Oxohexadecanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-15-Methylhexadecanoyl-ACPs + NADP
• [BioCyc:RXN1G-349] 3-oxo-arachidoyl-ACPs + NADPH + PROTON --> R-3-hydroxyarachidoyl-ACPs + NADP
• [BioCyc:RXN1G-182] cis,cis-delta5,23-3-oxo-C42:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-13369] 11-cis-3-hydroxyretinol-RBPs + NADP --> 11-cis-3-hydroxyretinal-RBPs + NADPH + PROTON
• [BioCyc:RXN1G-1247] cis,cis-delta15,33-3-oxo-C52:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-17986] Nonaketamide-OxyC + NADPH + PROTON --> C9-Reduced-Nonaketamide-OxyC + NADP
• [BioCyc:RXN66-633] Dodec-2-enoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Dodecanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN66-617] Crotonyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Butanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-21684] 6-Methyl-Hept-2-enoyl-ACPs + NADPH + PROTON --> 6-Methylheptanoyl-ACPs + NADP
• [BioCyc:RXN1G-384] cis,cis-delta7,25-3-oxo-C44:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-21635] 14-Methyl-3-Oxohexadecanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-14-Methylhexadecanoyl-ACPs + NADP
• [BioCyc:RXN-21618] 6-Methyl-3-Oxooctanoyl-ACP + NADPH + PROTON --> 3-Hydroxy-6-Methyloctanoyl-ACPs + NADP
• [BioCyc:RXN-9542] trans hexadecenoyl-[acp] reductase (NADPH, B-specific)
• [BioCyc:RXN3O-5293] Octadec-2-enoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Stearoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-21722] Icos-2-enoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Icosanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN1G-72] cis-delta5-3-oxo-C24:1-[acyl-carrier protein] reductase
• [BioCyc:RXN-21681] 6-Methyl-3-Oxoheptanoyl-ACP + NADPH + PROTON --> 3-Hydroxy-6-Methylheptanoyl-ACPs + NADP
• [BioCyc:RXN-21648] 5-Methylhexenoyl-ACP + NADPH + PROTON --> 5-Methylhexanoyl-ACP + NADP
• [BioCyc:RXN-9538] trans tetradec-2-enoyl-[acyl-carrier-protein] reductase
• [BioCyc:RXN66-627] 3-oxo-decanoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Beta-hydroxydecanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-22455] Octadec-2-enoyl-ACPs + NADPH + PROTON --> Stearoyl-ACPs + NADP
• [BioCyc:RXN-21694] 10-Methyl-Undec-2-enoyl-ACPs + NADPH + PROTON --> 10-Methylundecanoyl-ACPs + NADP
• [BioCyc:RXN-21645] 5-Methyl-3-Oxohexanoyl-ACP + NADPH + PROTON --> 5-Methyl-3-Hydroxyhexanoyl-ACP + NADP
• [BioCyc:RXN66-640] 3-oxo-palmitoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> R-3-Hydroxypalmitoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-21691] 10-Methyl-3-Oxoundecanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-10-Methylundecanoyl-ACPs + NADP
• [BioCyc:RXN1G-508] 3-oxo-lignoceroyl-[acyl-carrier protein] reductase
• [BioCyc:RXN-21658] 9-Methyl-Dec-2-enoyl-ACPs + NADPH + PROTON --> 9-Methyldecanoyl-ACPs + NADP
• [BioCyc:RXN-21642] 10-Methyl-Dodec-2-enoyl-ACPs + NADPH + PROTON --> 10-Methyldodecanoyl-ACPs + NADP
• [BioCyc:RXN-9554] Petrosel-2-enoyl-[acyl-carrier protein] reductase (NADPH, B-specific)
• [BioCyc:RXN66-621] Hex-2-enoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Hexanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN1G-881] cis-delta17-3-oxo-C36:1-[acyl-carrier protein] reductase
• [BioCyc:RXN-21705] 14-Methyl-Pentadec-2-enoyl-ACPs + NADPH + PROTON --> 14-Methylpentadecanoyl-ACPs + NADP
• [BioCyc:RXN1G-617] cis,cis-delta21,39-3-oxo-C58:2-[acyl-carrier protein] reductase
• [BioCyc:RXN1G-408] cis,cis-delta5,17-3-oxo-C36:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-21655] 9-Methyl-3-Oxo-Decanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-9-Methyldecanoyl-ACPs + NADP
• [BioCyc:RXN-21639] 4-Methylhexenoyl-ACP + NADPH + PROTON --> 4-Methylhexanoyl-ACP + NADP
• [BioCyc:RXN-21622] 8-Methyl-3-Oxo-Decanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-8-Methyldecanoyl-ACPs + NADP
• [BioCyc:RXN1G-184] cis,cis-delta17,35-3-oxo-C54:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-16622] 7Z-3-oxo-hexadec-7-enoyl-ACPs + NADPH + PROTON --> 3R-7Z-3-hydroxy-hexadec-7-enoyl-ACPs + NADP
• [BioCyc:RXN-21726] Docos-2-enoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> docosanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-21702] 14-Methyl-3-Oxopentadecanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-14-Methylpentadecanoyl-ACPs + NADP
• [BioCyc:RXN-21668] 13-Methyltetradec-2-enoyl-ACPs + NADPH + PROTON --> 13-methyltetradecanoyl-ACPs + NADP
• [BioCyc:RXN1G-252] cis,cis-delta9,21-3-oxo-C40:2-[acyl-carrier protein] reductase
• [BioCyc:RXN-13367] NADPH + PROTON + All-trans-3-hydroxyretinal-RBPs --> All-trans-3-hydroxyretinol-RBPs + NADP
• [BioCyc:RXN-10062] trans-hexacos-2-enoyl-[acp] reductase
• [BioCyc:RXN66-647] Trans-23-Dehydroacyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> Acyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN66-631] 3-oxo-dodecanoyl-TYPE-I-FAS-ACPs + NADPH + PROTON --> R-3-hydroxydodecanoyl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN66-614] Acetoacetyl-TYPE-I-FAS-ACP + NADPH + PROTON --> Beta-3-hydroxybutyryl-TYPE-I-FAS-ACPs + NADP
• [BioCyc:RXN-21665] 13-Methyl-3-Oxotetradecanoyl-ACPs + NADPH + PROTON --> 3-Hydroxy-13-Methyltetradecanoyl-ACPs + NADP
• [BioCyc:RXN1G-157] 3-oxo-behenoyl-[acyl-carrier protein] reductase
• [BioCyc:RXN-13361] 3S-11-cis-3-hydroxyretinol-RBPs + NADP --> 3S-11-cis-3-hydroxyretinal-RBPs + NADPH + PROTON
• [BioCyc:RXN-14664] Beta-OH-Tyr-S-NovH + NADP --> Beta-keto-Tyr-S-NovH + NADPH + PROTON

Metabolites

Substrates

metabolite	compartment	Structure
Formula:	Cytoplasm
NADP(3-) Formula: C21H25N7O17P3	Cytoplasm

Products

metabolite	compartment	Structure
Formula:	Cytoplasm
NADPH(4-) Formula: C21H26N7O17P3	Cytoplasm
H+ Formula: H	Cytoplasm