2 S-ADENOSYLMETHIONINE + a-pyruvate-dehydrogenase-E2-protein-Nsup + 2 Sulfurated-Sulfur-Acceptors + 2 Reduced-2Fe-2S-Ferredoxins --> Pyruvate-dehydrogenase-lipoate + 2 MET + 2 CH33ADO + 2 Unsulfurated-Sulfur-Acceptors + 2 Oxidized-2Fe-2S-Ferredoxins - 数据之源，洞见之始

BioCyc:RXN-14957

2 S-ADENOSYLMETHIONINE + a-pyruvate-dehydrogenase-E2-protein-Nsup + 2 Sulfurated-Sulfur-Acceptors + 2 Reduced-2Fe-2S-Ferredoxins --> Pyruvate-dehydrogenase-lipoate + 2 MET + 2 CH33ADO + 2 Unsulfurated-Sulfur-Acceptors + 2 Oxidized-2Fe-2S-Ferredoxins

2 S-Adenosylmethionine[C15H23N6O5S] + a [pyruvate dehydrogenase E2 protein] N⁶-octanoyl-L-lysine[] + 2 [] + 2 [] = a [pyruvate dehydrogenase E2 protein] N⁶-lipoyl-L-lysine[] + 2 L-Methionine[C5H11NO2S] + 2 5'-Deoxyadenosine[C10H13N5O3] + 2 [] + 2 []

DB Links

BioCyc: RXN-14957
EC Number: 2.8.1.8

Alias

[BioCyc:RXN-14957] 2 S-ADENOSYLMETHIONINE + a-pyruvate-dehydrogenase-E2-protein-Nsup + 2 Sulfurated-Sulfur-Acceptors + 2 Reduced-2Fe-2S-Ferredoxins --> Pyruvate-dehydrogenase-lipoate + 2 MET + 2 CH33ADO + 2 Unsulfurated-Sulfur-Acceptors + 2 Oxidized-2Fe-2S-Ferredoxins

Metabolites

Substrates

metabolite	compartment	Structure
S-Adenosylmethionine Formula: C15H23N6O5S	Cytoplasm
a [pyruvate dehydrogenase E2 protein] N⁶-octanoyl-L-lysine Formula:	Cytoplasm
Formula:	Cytoplasm
Formula:	Cytoplasm

Products

metabolite	compartment	Structure
a [pyruvate dehydrogenase E2 protein] N⁶-lipoyl-L-lysine Formula:	Cytoplasm
L-Methionine Formula: C5H11NO2S	Cytoplasm
5'-Deoxyadenosine Formula: C10H13N5O3	Cytoplasm
Formula:	Cytoplasm
Formula:	Cytoplasm