BioCyc:RXN-16016
This is a hypothetical reaction. No information about the exact order of events leading to the biosynthesis of |FRAME: ARACHIDONIC_ACID| by the polyketide synthase complex is available at this time |CITS: [25263707]|.
ACETYL-COA + 9 MALONYL-COA + 14 NADPH + 22 PROTON --> ARACHIDONIC_ACID + 9 CARBON-DIOXIDE + 10 CO-A + 8 WATER + 14 NADP
acetyl-CoA(4-)[C23H34N7O17P3S] + 9 Malonyl-CoA[C24H38N7O19P3S] + 14 NADPH(4-)[C21H26N7O17P3] + 22 H+[H] = Arachidonate[C20H32O2] + 9 CO2[CO2] + 10 coenzyme A(4-)[C21H32N7O16P3S] + 8 H2O[H2O] + 14 NADP(3-)[C21H25N7O17P3]
DB Links
- BioCyc: RXN-16016
- EC Number: 2.3.1.-
Alias
Metabolites
Substrates
| metabolite | compartment | Structure |
|---|---|---|
| acetyl-CoA(4-) Formula: C23H34N7O17P3S |
Cytoplasm | |
| Malonyl-CoA Formula: C24H38N7O19P3S |
Cytoplasm | |
| NADPH(4-) Formula: C21H26N7O17P3 |
Cytoplasm | |
| H+ Formula: H |
Cytoplasm |
Products
| metabolite | compartment | Structure |
|---|---|---|
| Arachidonate Formula: C20H32O2 |
Cytoplasm | |
| CO2 Formula: CO2 |
Cytoplasm | |
| coenzyme A(4-) Formula: C21H32N7O16P3S |
Cytoplasm | |
| H2O Formula: H2O |
Cytoplasm | |
| NADP(3-) Formula: C21H25N7O17P3 |
Cytoplasm |