KEGG:R00557

multi-step reaction (see R00558+R00111)

L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming)

2 L-Arginine[C6H14N4O2] + 4 Oxygen[O2] + 3 NADPH[C21H30N7O17P3] + 3 H+[H] = 2 Nitric oxide[NO] + 2 L-Citrulline[C6H13N3O3] + 3 NADP+[C21H29N7O17P3] + 4 H2O[H2O]

DB Links

Alias

Metabolites

Substrates
metabolite compartment Structure
L-Arginine

Formula: C6H14N4O2 		Cytoplasm
Oxygen

Formula: O2 		Cytoplasm
NADPH

Formula: C21H30N7O17P3 		Cytoplasm
H+

Formula: H 		Cytoplasm
Products
metabolite compartment Structure
Nitric oxide

Formula: NO		 Cytoplasm
L-Citrulline

Formula: C6H13N3O3		 Cytoplasm
NADP+

Formula: C21H29N7O17P3		 Cytoplasm
H2O

Formula: H2O		 Cytoplasm