KEGG:R00382

NAD+ + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Nicotinamide D-ribonucleotide + DNA(n+m)

(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming, NMN-forming)

NAD+[C21H28N7O14P2] + DNA[C10H17O8PR2(C5H8O5PR)n] + 5'-Phospho-DNA[C10H18O11P2R2(C5H8O5PR)n] = AMP[C10H14N5O7P] + Nicotinamide D-ribonucleotide[C11H15N2O8P] + DNA[C10H17O8PR2(C5H8O5PR)n]

DB Links

Alias

Metabolites

Substrates
metabolite compartment Structure
NAD+

Formula: C21H28N7O14P2 		Cytoplasm
DNA

Formula: C10H17O8PR2(C5H8O5PR)n 		Cytoplasm
5'-Phospho-DNA

Formula: C10H18O11P2R2(C5H8O5PR)n 		Cytoplasm
Products
metabolite compartment Structure
AMP

Formula: C10H14N5O7P		 Cytoplasm
Nicotinamide D-ribonucleotide

Formula: C11H15N2O8P		 Cytoplasm
DNA

Formula: C10H17O8PR2(C5H8O5PR)n		 Cytoplasm